JP2001521504A5 - - Google Patents

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Publication number
JP2001521504A5
JP2001521504A5 JP1998541945A JP54194598A JP2001521504A5 JP 2001521504 A5 JP2001521504 A5 JP 2001521504A5 JP 1998541945 A JP1998541945 A JP 1998541945A JP 54194598 A JP54194598 A JP 54194598A JP 2001521504 A5 JP2001521504 A5 JP 2001521504A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998541945A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001521504A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/006365 external-priority patent/WO1998043963A1/en
Publication of JP2001521504A publication Critical patent/JP2001521504A/ja
Publication of JP2001521504A5 publication Critical patent/JP2001521504A5/ja
Ceased legal-status Critical Current

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JP54194598A 1997-04-01 1998-03-31 メタロプロテイナーゼ阻害薬、それらを含有する薬剤組成物および薬剤としてのそれらの使用 Ceased JP2001521504A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82531897A 1997-04-01 1997-04-01
US08/825,318 1997-04-01
PCT/US1998/006365 WO1998043963A1 (en) 1997-04-01 1998-03-31 Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses

Publications (2)

Publication Number Publication Date
JP2001521504A JP2001521504A (ja) 2001-11-06
JP2001521504A5 true JP2001521504A5 (https=) 2005-11-24

Family

ID=25243697

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54194598A Ceased JP2001521504A (ja) 1997-04-01 1998-03-31 メタロプロテイナーゼ阻害薬、それらを含有する薬剤組成物および薬剤としてのそれらの使用

Country Status (8)

Country Link
EP (1) EP0973748A1 (https=)
JP (1) JP2001521504A (https=)
KR (1) KR20010005940A (https=)
AU (1) AU747280B2 (https=)
BR (1) BR9809062A (https=)
CA (1) CA2285372A1 (https=)
NZ (1) NZ338082A (https=)
WO (1) WO1998043963A1 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3621427B2 (ja) * 1997-07-22 2005-02-16 塩野義製薬株式会社 糸球体障害治療または予防剤
CA2298617A1 (en) 1997-07-31 1999-02-11 Yetunde Olabisi Taiwo Acyclic metalloprotease inhibitors
IL127496A0 (en) * 1997-12-19 1999-10-28 Pfizer Prod Inc The use of MMP inhibitors for the treatment of ocular angiogenesis
JP4750272B2 (ja) 1998-02-04 2011-08-17 ノバルティス アーゲー マトリックス分解メタロプロテイナーゼを阻害するスルホニルアミノ誘導体
US6410580B1 (en) 1998-02-04 2002-06-25 Novartis Ag Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases
US6075136A (en) * 1998-02-17 2000-06-13 Incyte Pharmaceuticals, Inc. Prostate-associated serine protease
US6492394B1 (en) 1998-12-22 2002-12-10 Syntex (U.S.A.) Llc Sulfonamide hydroxamates
US6200996B1 (en) 1999-01-27 2001-03-13 American Cyanamid Company Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors
US6326516B1 (en) 1999-01-27 2001-12-04 American Cyanamid Company Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors
US6225311B1 (en) 1999-01-27 2001-05-01 American Cyanamid Company Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors
US6313123B1 (en) 1999-01-27 2001-11-06 American Cyanamid Company Acetylenic sulfonamide thiol tace inhibitors
US6753337B2 (en) 1999-01-27 2004-06-22 Wyeth Holdings Corporation Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
US6762178B2 (en) 1999-01-27 2004-07-13 Wyeth Holdings Corporation Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6946473B2 (en) 1999-01-27 2005-09-20 Wyeth Holdings Corporation Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors
US6277885B1 (en) 1999-01-27 2001-08-21 American Cyanamid Company Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6340691B1 (en) 1999-01-27 2002-01-22 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors
US6358980B1 (en) 1999-01-27 2002-03-19 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
MXPA01008857A (es) 1999-03-03 2002-07-02 Procter & Gamble Inhibidores de metaloproteasa dihetero sustituidos.
BR0008716A (pt) 1999-03-03 2002-09-24 Procter & Gamble Inibidores de metaloprotease contendo alquenil ou alquinil
US6696456B1 (en) * 1999-10-14 2004-02-24 The Procter & Gamble Company Beta disubstituted metalloprotease inhibitors
BR0213736A (pt) 2001-11-01 2004-10-19 Wyeth Corp ácidos hidroxâmicos de sulfonamida de arila alênica como metaloproteinase matriz e inibidores de tace
PE20030701A1 (es) 2001-12-20 2003-08-21 Schering Corp Compuestos para el tratamiento de trastornos inflamatorios
WO2003055851A1 (en) 2001-12-27 2003-07-10 Sumitomo Pharmaceuticals Company, Limited Hydroxamic acid derivative and mmp inhibitor containing the same as active ingredient
EP2436676A1 (en) * 2002-06-12 2012-04-04 Symphony Evolution, Inc. Human adam-10 inhibitors
US7199155B2 (en) 2002-12-23 2007-04-03 Wyeth Holdings Corporation Acetylenic aryl sulfonate hydroxamic acid TACE and matrix metalloproteinase inhibitors
WO2008070579A2 (en) * 2006-12-01 2008-06-12 Loma Linda University Medical Center Inhibition of brain enzymes involved in cerebral amyloid angiopathy and macular degeneration
CN113194954A (zh) 2018-10-04 2021-07-30 国家医疗保健研究所 用于治疗角皮病的egfr抑制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2193691A1 (en) * 1994-06-22 1995-12-28 Andrew Miller Metalloproteinase inhibitors
US5863949A (en) * 1995-03-08 1999-01-26 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
PT757984E (pt) * 1995-08-08 2003-02-28 Ono Pharmaceutical Co Derivados de acido hidroxamico uteis para inibir a gelatinase
ES2233275T3 (es) * 1995-12-08 2005-06-16 Agouron Pharmaceuticals, Inc. Intermediarios que sirven para la preparacion de inhibidores de metaloproteinasas.
BR9707010B1 (pt) * 1996-01-23 2009-05-05 compostos, composição farmacêutica e composições para inibir metaloproteinase e colagenase do tipo iv.

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