JP2001516732A - 置換テトラヒドロナフタリンおよび類似化合物 - Google Patents

置換テトラヒドロナフタリンおよび類似化合物

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Publication number
JP2001516732A
JP2001516732A JP2000511728A JP2000511728A JP2001516732A JP 2001516732 A JP2001516732 A JP 2001516732A JP 2000511728 A JP2000511728 A JP 2000511728A JP 2000511728 A JP2000511728 A JP 2000511728A JP 2001516732 A JP2001516732 A JP 2001516732A
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JP
Japan
Prior art keywords
carbon atoms
straight
chain
phenyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000511728A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001516732A5 (https=
Inventor
ブランデス，アルント
レゲルス，ミヒヤエル
シユトルテフス，ユルゲン
シユミツト，グンター
ブレム，クラウス−デイーター
ビシヨフ，ヒルマー
シユミツト，デルフ
アントンス，シユテフアン
パウルゼン，ホルガー
ミユラー，シユテフアン・ニコラス
ナープ，パウル
シユメク，カルステン
Original Assignee
バイエル・アクチエンゲゼルシヤフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19832159A external-priority patent/DE19832159A1/de
Application filed by バイエル・アクチエンゲゼルシヤフト filed Critical バイエル・アクチエンゲゼルシヤフト
Publication of JP2001516732A publication Critical patent/JP2001516732A/ja
Publication of JP2001516732A5 publication Critical patent/JP2001516732A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/48—Halogenated derivatives
    • C07C35/52—Alcohols with a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/18—Ethers having an ether-oxygen atom bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C43/192—Ethers having an ether-oxygen atom bound to a carbon atom of a ring other than a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP2000511728A 1997-09-18 1998-09-16 置換テトラヒドロナフタリンおよび類似化合物 Pending JP2001516732A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19741050 1997-09-18
DE19741050.2 1997-09-18
DE19832159.7 1998-07-17
DE19832159A DE19832159A1 (de) 1997-09-18 1998-07-17 Substituierte Tetrahydro-naphthaline
PCT/EP1998/005874 WO1999014174A1 (de) 1997-09-18 1998-09-16 Substituierte tetrahydro-naphtaline und analoge verbindungen

Publications (2)

Publication Number Publication Date
JP2001516732A true JP2001516732A (ja) 2001-10-02
JP2001516732A5 JP2001516732A5 (https=) 2006-01-05

Family

ID=26040079

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000511728A Pending JP2001516732A (ja) 1997-09-18 1998-09-16 置換テトラヒドロナフタリンおよび類似化合物

Country Status (9)

Country Link
US (1) US6586613B1 (https=)
EP (1) EP1017659B1 (https=)
JP (1) JP2001516732A (https=)
AT (1) ATE294152T1 (https=)
AU (1) AU9744298A (https=)
ES (1) ES2242302T3 (https=)
MA (1) MA24643A1 (https=)
PT (1) PT1017659E (https=)
WO (1) WO1999014174A1 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009530322A (ja) * 2006-03-18 2009-08-27 バイエル・ヘルスケア・アクチェンゲゼルシャフト 置換クロマノール誘導体およびそれらの使用
EP2316447A1 (en) 2003-09-26 2011-05-04 Japan Tobacco, Inc. Method of inhibiting remnant lipoprotein production
KR101764458B1 (ko) 2010-07-09 2017-08-02 다이이찌 산쿄 가부시키가이샤 치환 피리딘 화합물
JP2017526750A (ja) * 2014-09-09 2017-09-14 ベーリンガー インゲルハイム インターナショナル トレイディング （シャンハイ） カンパニー リミテッド スピロ［２．５］オクタン−５，７−ジオンおよびスピロ［３．５］ノナン−６，８−ジオンの調製のための新規なプロセス

Families Citing this family (26)

* Cited by examiner, † Cited by third party
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US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6489366B1 (en) 1998-12-23 2002-12-03 G. D. Searle, Llc Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acid derivatives for cardiovascular indications
DE19935966A1 (de) * 1999-07-30 2001-02-01 Bayer Ag Verfahren zur Reduktion von Ketoalkoholen
US7115279B2 (en) 2000-08-03 2006-10-03 Curatolo William J Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors
EP1269994A3 (en) 2001-06-22 2003-02-12 Pfizer Products Inc. Pharmaceutical compositions comprising drug and concentration-enhancing polymers
EE200400034A (et) 2001-06-22 2004-06-15 Pfizer Products Inc. Amorfse ravimaine adsorbaatide farmatseutilised kompositsioonid
WO2003000235A1 (en) 2001-06-22 2003-01-03 Pfizer Products Inc. Pharmaceutical compositions of dispersions of drugs and neutral polymers
DE10148436A1 (de) * 2001-10-01 2003-04-17 Bayer Ag Tetrahydrochinoline
FR2832919B1 (fr) 2001-12-04 2004-02-20 Imv Technologies Seringue d'injection du contenu d'une paillette pour l'insemination artificielle d'un animal ou le transfert embryonnaire
AU2002361811A1 (en) 2001-12-19 2003-07-09 Atherogenics, Inc. 1,3-bis-(substituted-phenyl)-2-propyn-1-ones and their use to treat disorders
CN1596240A (zh) 2001-12-19 2005-03-16 阿特罗吉尼克斯公司 查耳酮衍生物及其治疗疾病的用途
BR0306643A (pt) 2002-01-17 2004-10-19 Pharmacia Corp Novos compostos de hidroxi alquil/aril ou ceto tiepina como inibidores do transporte co-dependente de ácido biliar-sódio apical
ATE395044T1 (de) 2002-02-01 2008-05-15 Pfizer Prod Inc Pharmazeutische zusammensetzungen amorpher dispersionen von wirkstoffen und lipophiler mikrophasenbildender materialien
AR038375A1 (es) 2002-02-01 2005-01-12 Pfizer Prod Inc Composiciones farmaceuticas de inhibidores de la proteina de transferencia de esteres de colesterilo
EP1961419B1 (en) 2002-12-20 2010-03-24 Pfizer Products Inc. Dosage forms comprising a CETP inhibitor and an HMG-CoA reductase inhibitor
MXPA05009848A (es) 2003-03-17 2005-12-06 Japan Tobacco Inc Composiciones farmaceuticas de inhibidores de la proteina de transferencia del ester de colesterilo.
TWI494102B (zh) * 2003-05-02 2015-08-01 Japan Tobacco Inc 包含ｓ-〔２（〔〔１-（２-乙基丁基）環己基〕羰基〕胺基）苯基〕２-甲基丙烷硫酯及ｈｍｇ輔酶ａ還原酶抑制劑之組合
CL2004001884A1 (es) 2003-08-04 2005-06-03 Pfizer Prod Inc Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
JP2007501218A (ja) 2003-08-04 2007-01-25 ファイザー・プロダクツ・インク 非晶質薬物の吸着物および親油性ミクロ相形成物質の医薬組成物
WO2006063828A1 (de) * 2004-12-18 2006-06-22 Bayer Healthcare Ag 4-cycloalkyl-substituierte tetrahydrochinolinderivate und deren verwendung als medikamente
EP1844078B1 (en) 2005-02-03 2016-09-28 Bend Research, Inc Pharmaceutical compositions with enhanced performance
US7737155B2 (en) 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
WO2007048027A2 (en) 2005-10-21 2007-04-26 Novartis Ag Combination of a renin-inhibitor and an anti-dyslipidemic agent and/or an antiobesity agent
DK2268644T3 (da) * 2008-03-05 2011-10-10 Boehringer Ingelheim Int Tricycliske pyridinderivater, medikamenter indeholdende sådanne forbindelser, deres anvendelse og fremgangsmåde til deres fremstilling
US20110245209A1 (en) 2008-12-16 2011-10-06 Schering Corporation Pyridopyrimidine derivatives and methods of use thereof
WO2010075069A1 (en) 2008-12-16 2010-07-01 Schering Corporation Bicyclic pyranone derivatives as nicotinic acid receptor agonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169857A (en) 1988-01-20 1992-12-08 Bayer Aktiengesellschaft 7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis
US5446207A (en) * 1993-09-01 1995-08-29 Harbor Branch Oceanographic Institution, Inc. Anti-dyslipidemic agents
HRP970330B1 (en) 1996-07-08 2004-06-30 Bayer Ag Cycloalkano pyridines

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2316447A1 (en) 2003-09-26 2011-05-04 Japan Tobacco, Inc. Method of inhibiting remnant lipoprotein production
EP2319509A1 (en) 2003-09-26 2011-05-11 Japan Tobacco, Inc. Method of Inhibiting remnant lipoprotein production
JP2009530322A (ja) * 2006-03-18 2009-08-27 バイエル・ヘルスケア・アクチェンゲゼルシャフト 置換クロマノール誘導体およびそれらの使用
KR101764458B1 (ko) 2010-07-09 2017-08-02 다이이찌 산쿄 가부시키가이샤 치환 피리딘 화합물
JP2017526750A (ja) * 2014-09-09 2017-09-14 ベーリンガー インゲルハイム インターナショナル トレイディング （シャンハイ） カンパニー リミテッド スピロ［２．５］オクタン−５，７−ジオンおよびスピロ［３．５］ノナン−６，８−ジオンの調製のための新規なプロセス

Also Published As

Publication number Publication date
AU9744298A (en) 1999-04-05
ES2242302T3 (es) 2005-11-01
PT1017659E (pt) 2005-09-30
MA24643A1 (fr) 1999-04-01
EP1017659A1 (de) 2000-07-12
ATE294152T1 (de) 2005-05-15
EP1017659B1 (de) 2005-04-27
US6586613B1 (en) 2003-07-01
WO1999014174A1 (de) 1999-03-25

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