JP2001515593A - 組織学上の試料を処理しかつ浸潤させる装置 - Google Patents
組織学上の試料を処理しかつ浸潤させる装置Info
- Publication number
- JP2001515593A JP2001515593A JP54040598A JP54040598A JP2001515593A JP 2001515593 A JP2001515593 A JP 2001515593A JP 54040598 A JP54040598 A JP 54040598A JP 54040598 A JP54040598 A JP 54040598A JP 2001515593 A JP2001515593 A JP 2001515593A
- Authority
- JP
- Japan
- Prior art keywords
- casing
- ring
- histological
- processing
- container
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007788 liquid Substances 0.000 claims abstract description 59
- 230000008595 infiltration Effects 0.000 claims abstract description 16
- 238000001764 infiltration Methods 0.000 claims abstract description 16
- 239000000463 material Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 description 9
- 239000003153 chemical reaction reagent Substances 0.000 description 6
- 239000001993 wax Substances 0.000 description 6
- 238000005119 centrifugation Methods 0.000 description 4
- 239000012188 paraffin wax Substances 0.000 description 4
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 2
- 238000005352 clarification Methods 0.000 description 2
- 230000018044 dehydration Effects 0.000 description 2
- 238000006297 dehydration reaction Methods 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 1
- 239000008395 clarifying agent Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- -1 for example Substances 0.000 description 1
- 239000008098 formaldehyde solution Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N2001/315—Basket-type carriers for tissues
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1. 組織学上の試料を処理しかつ浸潤させる装置であって、ケーシング内に取り 付けられ組織学上の試料を入れたカセットのための容器を取り付けられている回 転軸を有している回転手段と、可変の速度で回転軸を回転させるための手段と、 ケーシングの外方に配置されている処理液体タンク及び浸潤液体タンクと、これ らの液体をケーシング内に供給しかつケーシングから取り出すための短管とを有 している形式のものにおいて、回転軸がケーシング内で水平に配置されているこ とを特徴とする、組織学上の試料を処理しかつ浸潤させる装置。 2. 組織学上の試料を入れたカセットのための容器がリングセクタの形に構成さ れていることを特徴とする、請求項1記載の装置。 3. 組織学上の試料を入れたリングセクタの形に構成されたカセットがリング形 に配置されていることを特徴とする、請求項1記載の装置。 4. 容器リングの内径が組織学上の試料を入れたカセットの幅の2〜4倍である ことを特徴とする、請求項3記載の装置。 5. リング形に配置されている容器が回転軸上で、回転軸に対して垂直な平面内 に固定されていることを特徴とする、請求項1記載の装置。 6. 組織学上の試料を入れたカセットのための容器が有孔であることを特徴とす る、請求項2記載の装置。 7. 液面センサを備えており、この液面センサはケーシング壁に、回転軸よりも 高くなく、容器リングの内筒の最下点よりも低くない高さのところで取り付けら れていることを特徴とする、請求項1記載の装置。 8. 組織学上の試料を処理しかつ浸潤させる装置であって、ケーシング内に取り 付けられ組織学上の試料を入れたカセットのための容器を取り付けられている回 転軸を有している回転手段と、可変の速度で回転軸を回転させるための手段と、 ケーシングの外方に配置されている処理液体タンク及び浸潤液体タンクと、これ らの液体をケーシング内に供給しかつケーシングから取り出すための短管とを有 している形式のものにおいて、回転手段の回転軸がケーシング内で水平に配置さ れていて、組織学上の試料を入れたカセットのための容器がリングセクタの形に 構成されていて、リング形に配置されており、このリングの内径は組織学上の試 料を入れたカセットの幅の2〜4倍であり、容器リングが回転軸上で鉛直平面内 に配置されていることを特徴とする、組織学上の試料を処理しかつ浸潤させる装 置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU97104413 | 1997-03-17 | ||
RU97104413A RU2150097C1 (ru) | 1997-03-17 | 1997-03-17 | Устройство для обработки и пропитки гистологических образцов |
PCT/RU1998/000053 WO1998041837A1 (en) | 1997-03-17 | 1998-02-27 | Device for the processing and infiltration of histological specimens |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2001515593A true JP2001515593A (ja) | 2001-09-18 |
JP3973696B2 JP3973696B2 (ja) | 2007-09-12 |
Family
ID=20191034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP54040598A Expired - Lifetime JP3973696B2 (ja) | 1997-03-17 | 1998-02-27 | 組織学上の試料を処理しかつ浸潤させる装置 |
Country Status (6)
Country | Link |
---|---|
US (1) | US6413767B1 (ja) |
EP (1) | EP0969277B1 (ja) |
JP (1) | JP3973696B2 (ja) |
DE (1) | DE59814164D1 (ja) |
RU (1) | RU2150097C1 (ja) |
WO (1) | WO1998041837A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2020112464A (ja) * | 2019-01-15 | 2020-07-27 | サクラ精機株式会社 | 組織片処理装置 |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10163487B4 (de) * | 2001-12-21 | 2005-05-25 | Microm International Gmbh | Behandlungskammer für die Behandlung von histologischen Proben |
DE10163488A1 (de) | 2001-12-21 | 2003-07-10 | Microm Int Gmbh | Vorrichtung zur Behandlung von histologischen Proben |
US7541161B2 (en) * | 2002-10-31 | 2009-06-02 | University Of Massachusetts | Method and apparatus for preparing cells for microtome sectioning and archiving nucleic acids and proteins |
ES2372169T3 (es) * | 2002-10-31 | 2012-01-16 | University Of Massachusetts | Método y aparato de empotramiento rápido de bloques con células. |
US7769962B2 (en) * | 2005-12-12 | 2010-08-03 | Jeda Technologies, Inc. | System and method for thread creation and memory management in an object-oriented programming environment |
US20080145891A1 (en) * | 2006-12-15 | 2008-06-19 | Brian Christopher Burton | Apparatus and method for processing histological specimens |
US7906076B2 (en) * | 2007-07-02 | 2011-03-15 | University Of Massachusetts | Method and apparatus for biopsy sample processing |
DE102011002195B4 (de) | 2011-04-20 | 2020-07-02 | Leica Biosystems Nussloch Gmbh | Verfahren und Vorrichtung zum Ablösen und/oder Vereinzeln einer histologischen Probe |
DE102011002197B4 (de) * | 2011-04-20 | 2019-03-07 | Leica Biosystems Nussloch Gmbh | Verfahren und Vorrichtung zum Ablösen und/oder Vereinzeln einer histologischen Probe |
CN102961998B (zh) * | 2012-11-23 | 2014-10-22 | 西安医学院第二附属医院 | 一种用于微生物和分子生物实验的旋转摇床 |
WO2015072876A1 (ru) * | 2013-11-14 | 2015-05-21 | Илья Борисович ИЗВОЗЧИКОВ | Устройство для очистки гистологического тканевого процессора |
EP2927664A1 (de) | 2014-04-04 | 2015-10-07 | Aurel Popa | Vorrichtung zur gleichzeitigen Präparation einer Mehrzahl von Frischgewebeschnitten sowie ein Durchführungsverfahren |
WO2019216783A1 (ru) | 2018-05-07 | 2019-11-14 | Tjan Eleonora Iljinichna | Устройство для обработки и пропитки гистологических и биологических образцов |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU93155A1 (ru) * | 1950-10-19 | 1951-11-30 | мастерские при Экспериментальном институте биологии и патологии им. акад. А.А. Богомольца Министерства здравоохранения УССР Экспериментально-конструкторские | Автомат дл гистологической обработки тканей |
US3491778A (en) * | 1967-01-17 | 1970-01-27 | Kabel Metallwerke Ghh | Method and apparatus for cleaning and degreasing metal articles |
US3435835A (en) * | 1967-05-10 | 1969-04-01 | American Home Prod | Cap washing machine |
US4089989A (en) * | 1975-04-04 | 1978-05-16 | White Ronald D | Method for preparing microscope slides by rotating during coating |
SE7801564L (sv) * | 1978-02-10 | 1979-08-11 | Lkb Produkter Ab | Anordning for infergning av biologiska preparat |
DE3042578A1 (de) | 1980-11-12 | 1982-06-24 | C. Reichert Optische Werke Ag, Wien | Inkubationseinrichtung zur fixation, entwaesserung und einbettung biologischer objekte fuer mikroskopische, insbesondere elektronenmikroskopische untersuchungen |
US4353381A (en) * | 1981-02-27 | 1982-10-12 | Winters Stephen G | Fluid cleaner apparatus |
DE3270449D1 (en) | 1981-10-20 | 1986-05-15 | Shandon Southern Prod | Tissue processing apparatus |
US4576796A (en) * | 1984-01-18 | 1986-03-18 | Pelam, Inc. | Centrifugal tissue processor |
NZ212428A (en) * | 1984-06-19 | 1988-05-30 | William Mcclean | Identification marker for identification of histology samples |
GB8628371D0 (en) | 1986-11-27 | 1986-12-31 | Shandon Southern Prod | Tissue specimen treatment apparatus |
EP0418026B1 (en) * | 1989-09-13 | 1994-11-30 | Kabushiki Kaisha Tiyoda Seisakusho | Apparatus for pretreating cells for flow cytometry |
GB9004596D0 (en) * | 1990-03-01 | 1990-04-25 | Amersham Int Plc | Apparatus for treating analytes |
DE4200446C2 (de) * | 1991-12-14 | 1994-04-07 | Will Prof Dr Minuth | Zellträgeranordnung |
-
1997
- 1997-03-17 RU RU97104413A patent/RU2150097C1/ru not_active IP Right Cessation
-
1998
- 1998-02-27 WO PCT/RU1998/000053 patent/WO1998041837A1/ru active IP Right Grant
- 1998-02-27 EP EP98914176A patent/EP0969277B1/de not_active Expired - Lifetime
- 1998-02-27 US US09/380,232 patent/US6413767B1/en not_active Expired - Lifetime
- 1998-02-27 JP JP54040598A patent/JP3973696B2/ja not_active Expired - Lifetime
- 1998-02-27 DE DE59814164T patent/DE59814164D1/de not_active Expired - Lifetime
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2020112464A (ja) * | 2019-01-15 | 2020-07-27 | サクラ精機株式会社 | 組織片処理装置 |
JP7215909B2 (ja) | 2019-01-15 | 2023-01-31 | サクラ精機株式会社 | 組織片処理装置 |
Also Published As
Publication number | Publication date |
---|---|
WO1998041837A8 (fr) | 1999-09-02 |
US6413767B1 (en) | 2002-07-02 |
EP0969277A4 (de) | 2006-09-06 |
DE59814164D1 (de) | 2008-03-20 |
EP0969277B1 (de) | 2008-02-06 |
RU2150097C1 (ru) | 2000-05-27 |
EP0969277A1 (de) | 2000-01-05 |
WO1998041837A1 (en) | 1998-09-24 |
JP3973696B2 (ja) | 2007-09-12 |
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