JP2001515480A5 - - Google Patents

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Publication number
JP2001515480A5
JP2001515480A5 JP1998538315A JP53831598A JP2001515480A5 JP 2001515480 A5 JP2001515480 A5 JP 2001515480A5 JP 1998538315 A JP1998538315 A JP 1998538315A JP 53831598 A JP53831598 A JP 53831598A JP 2001515480 A5 JP2001515480 A5 JP 2001515480A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP1998538315A
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English (en)
Japanese (ja)
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JP4095676B2 (ja
JP2001515480A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/IB1998/000508 external-priority patent/WO1998039000A1/en
Publication of JP2001515480A publication Critical patent/JP2001515480A/ja
Publication of JP2001515480A5 publication Critical patent/JP2001515480A5/ja
Application granted granted Critical
Publication of JP4095676B2 publication Critical patent/JP4095676B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP53831598A 1997-03-03 1998-03-03 注意障害を治療するためのコリンエステラーゼ阻害剤の使用 Expired - Lifetime JP4095676B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3983297P 1997-03-03 1997-03-03
US60/039,832 1997-03-03
PCT/IB1998/000508 WO1998039000A1 (en) 1997-03-03 1998-03-03 Use of cholinesterase inhibitors to treat disorders of attention

Publications (3)

Publication Number Publication Date
JP2001515480A JP2001515480A (ja) 2001-09-18
JP2001515480A5 true JP2001515480A5 (cg-RX-API-DMAC7.html) 2004-07-15
JP4095676B2 JP4095676B2 (ja) 2008-06-04

Family

ID=21907565

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53831598A Expired - Lifetime JP4095676B2 (ja) 1997-03-03 1998-03-03 注意障害を治療するためのコリンエステラーゼ阻害剤の使用

Country Status (12)

Country Link
US (2) US6455544B1 (cg-RX-API-DMAC7.html)
EP (1) EP0971713B1 (cg-RX-API-DMAC7.html)
JP (1) JP4095676B2 (cg-RX-API-DMAC7.html)
AT (1) ATE241358T1 (cg-RX-API-DMAC7.html)
AU (1) AU743609B2 (cg-RX-API-DMAC7.html)
CA (1) CA2282654C (cg-RX-API-DMAC7.html)
DE (1) DE69815090T2 (cg-RX-API-DMAC7.html)
DK (1) DK0971713T3 (cg-RX-API-DMAC7.html)
ES (1) ES2200313T3 (cg-RX-API-DMAC7.html)
NZ (1) NZ337515A (cg-RX-API-DMAC7.html)
PT (1) PT971713E (cg-RX-API-DMAC7.html)
WO (1) WO1998039000A1 (cg-RX-API-DMAC7.html)

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* Cited by examiner, † Cited by third party
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PT971713E (pt) * 1997-03-03 2003-09-30 Eisai Co Ltd Utilizacao de inibidores da colinesterase para tratamento de desordens da atencao
GB9716879D0 (en) * 1997-08-08 1997-10-15 Shire Int Licensing Bv Treatment of attention deficit disorders
US6429207B1 (en) 1997-11-21 2002-08-06 Nps Pharmaceuticals, Inc. Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases
EP1764101A1 (en) * 2000-03-03 2007-03-21 Eisai R&D Management Co., Ltd. Use of a cholinesterase inhibitor for the treatment of dementia and cognitive impairments
EP2133078A1 (en) * 2000-03-03 2009-12-16 Eisai R&D Management Co., Ltd. Use of a cholinesterase inhibitor for the treatment of dementia and cognitive impairments
US20060183776A9 (en) * 2000-03-03 2006-08-17 Eisai Co., Ltd. Liquid dosage formulations of donepezil
US20030153598A1 (en) * 2000-07-25 2003-08-14 Raymond Pratt Methods for treating Parkinson's disease with cholinesterase inhibitors
JP2006516948A (ja) * 2000-11-14 2006-07-13 ニュー リバー ファーマシューティカルズ インコーポレイテッド 硫酸アバカビルを含有する新規な薬剤化合物および同化合物の製造ならびに使用方法
WO2004034963A2 (en) * 2002-05-17 2004-04-29 Eisai Co., Ltd. Methods and compositions using cholinesterase inhibitors
US20070053976A1 (en) * 2002-05-17 2007-03-08 Eisai R & D Management Co., Ltd. Novel combination of drugs as antidepressant
US7842693B2 (en) * 2002-06-12 2010-11-30 Chemocentryx, Inc. Substituted piperazines
US20050256130A1 (en) * 2002-06-12 2005-11-17 Chemocentryx, Inc. Substituted piperazines
US7589199B2 (en) * 2002-06-12 2009-09-15 Chemocentryx, Inc. Substituted piperazines
AU2003236500B9 (en) 2002-06-12 2009-07-02 Chemocentryx, Inc. 1-aryl-4-substituted piperazine derivatives for use as CCR1 antagonists for the treatment of inflammation and immune disorders
EP1776089A2 (en) * 2003-12-31 2007-04-25 Actavis Group hf Donepezil formulations
US7435831B2 (en) 2004-03-03 2008-10-14 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
JP4845873B2 (ja) * 2004-03-03 2011-12-28 ケモセントリックス インコーポレーティッド 二環式および架橋した窒素複素環
WO2005105742A1 (ja) * 2004-04-28 2005-11-10 Eisai R&D Management Co., Ltd. 1-ベンジル-4-[(5,6-ジメトキシ-1-インダノン)-2-イル]メチルピペリジンおよびその塩酸塩の製造法
WO2006036936A2 (en) * 2004-09-27 2006-04-06 Bridge Pharma, Inc. The s-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents
US20060079558A1 (en) * 2004-09-27 2006-04-13 Bridge Pharma. Inc. R-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine and other dermal anesthetics
ATE523199T1 (de) 2004-11-02 2011-09-15 Univ Northwestern Pyridazinverbindungen und verfahren
AU2006209216A1 (en) 2005-01-25 2006-08-03 Galenea Corp Substituted arylamine compounds and their use as 5-HT6 modulators
EP1871368B1 (en) * 2005-04-04 2011-06-08 Eisai R&D Management Co., Ltd. Dihydropyridine compounds for neurodegenerative diseases and dementia
WO2007043440A1 (ja) * 2005-10-14 2007-04-19 Eisai R & D Management Co., Ltd. 1-ベンジル-4-[(5,6-ジメトキシ-1-インダノン)-2-イル]メチルピペリジンまたはその塩酸塩の製造法
EP1960357A2 (en) * 2005-11-14 2008-08-27 Medichem S.A. Synthesis and preparations of intermediates and polymorphs thereof useful for the preparation of donepezil hydrochloride
EP2015750A2 (en) 2006-04-28 2009-01-21 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
WO2008011161A2 (en) * 2006-07-21 2008-01-24 Bridge Pharma, Inc. Dermal anesthetic compounds
CA2671006A1 (en) * 2006-12-01 2008-06-05 Nitto Denko Corporation Method for suppressing discoloration over time of adhesive preparation containing donepezil
CN101588802A (zh) * 2006-12-01 2009-11-25 日东电工株式会社 含有稳定化的多奈哌齐的贴剂
US20100099714A1 (en) * 2007-03-05 2010-04-22 Eisai R&D Management Co., Ltd. AMPA and NMDA Receptor Antagonists for Neurodegenerative Diseases
JP2010524844A (ja) * 2007-04-26 2010-07-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 認知症のためのシンナミド化合物
KR100914691B1 (ko) * 2007-08-10 2009-08-28 주식회사유한양행 도네페질 또는 그의 제조용 중간체의 제조방법
CA2725484A1 (en) * 2008-05-30 2009-12-03 Eisai R&D Management Co., Ltd. Percutaneously absorbable preparation
CN102014905B (zh) * 2008-05-30 2012-11-14 日东电工株式会社 含有多奈哌齐的贴剂及其包装体
EA037187B1 (ru) 2010-02-09 2021-02-17 Дзе Джонс Хопкинс Юниверсити Способ и композиция для лечения когнитивного расстройства
WO2012071369A2 (en) 2010-11-24 2012-05-31 The Trustees Of Columbia University In The City Of New York A non-retinoid rbp4 antagonist for treatment of age-related macular degeneration and stargardt disease
WO2013166037A1 (en) 2012-05-01 2013-11-07 The Trustees Of Columbia University In The City Of New York Non-retinoid antagonists for treatment of eye disorders
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
US10273243B2 (en) 2013-03-14 2019-04-30 The Trustees Of Columbia University In The City Of New York 4-phenylpiperidines, their preparation and use
WO2014151936A1 (en) 2013-03-14 2014-09-25 The Trustees Of Columbia University In The City Of New York Octahydropyrrolopyrroles, their preparation and use
WO2014152018A1 (en) 2013-03-14 2014-09-25 The Trustees Of Columbia University In The City Of New York Octahydrocyclopentapyrroles, their preparation and use
US9938291B2 (en) 2013-03-14 2018-04-10 The Trustess Of Columbia University In The City Of New York N-alkyl-2-phenoxyethanamines, their preparation and use
CA2904767C (en) 2013-03-15 2022-06-21 Agenebio, Inc. Methods and compositions for improving cognitive function
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
CA2947174C (en) 2014-04-30 2023-02-28 The Trustees Of Columbia University In The City Of New York Substituted 4-phenylpiperidines, their preparaiton and use
KR101732776B1 (ko) * 2014-10-08 2017-05-04 영남대학교 산학협력단 신규한 인데노 피리디니움 유도체 화합물 및 이의 제조방법
EA034167B8 (ru) 2015-05-22 2021-04-27 Эйджинбайо, Инк. Фармацевтические композиции леветирацетама пролонгированного высвобождения

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
US5064858A (en) * 1988-08-17 1991-11-12 Spectrum Pharmaceutical Corporation Protected complex of procaine for the treatment of symptoms from narcotics addiction, tinnitus and Alzheimer's disease
MXPA98000395A (es) * 1995-07-14 2005-04-29 Medeva Europ Ltd Composicion que comprende d-treo-metilfenidato y otra droga.
RU2190603C2 (ru) * 1996-06-07 2002-10-10 Эйсай Ко., Лтд. Полиморфные модификации донепезила гидрохлорида, способы их получения и способ лечения заболевания, сопровождающегося активностью ацетилхолинэстеразы
PT971713E (pt) * 1997-03-03 2003-09-30 Eisai Co Ltd Utilizacao de inibidores da colinesterase para tratamento de desordens da atencao

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