JP2001511463A5 - - Google Patents
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- Publication number
- JP2001511463A5 JP2001511463A5 JP2000504921A JP2000504921A JP2001511463A5 JP 2001511463 A5 JP2001511463 A5 JP 2001511463A5 JP 2000504921 A JP2000504921 A JP 2000504921A JP 2000504921 A JP2000504921 A JP 2000504921A JP 2001511463 A5 JP2001511463 A5 JP 2001511463A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- preventing
- metastatic growth
- reducing metastatic
- surgery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000006510 metastatic growth Effects 0.000 description 4
- RJGYJMFQWGPBGM-UHFFFAOYSA-N 1,2,4-thiadiazinane 1,1-dioxide Chemical compound O=S1(=O)CCNCN1 RJGYJMFQWGPBGM-UHFFFAOYSA-N 0.000 description 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- AJKIRUJIDFJUKJ-UHFFFAOYSA-N taurolidine Chemical compound C1NS(=O)(=O)CCN1CN1CNS(=O)(=O)CC1 AJKIRUJIDFJUKJ-UHFFFAOYSA-N 0.000 description 2
- 229960004267 taurolidine Drugs 0.000 description 2
- 229950007343 taurultam Drugs 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 239000002628 heparin derivative Substances 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 238000002357 laparoscopic surgery Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002324 minimally invasive surgery Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9716219.2 | 1997-07-31 | ||
| GBGB9716219.2A GB9716219D0 (en) | 1997-07-31 | 1997-07-31 | Prevention of metastases |
| PCT/GB1998/002311 WO1999006114A2 (en) | 1997-07-31 | 1998-07-31 | Use of taurolidine or taurultam for the manufacture of a medicament for the prevention of metastases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010029152A Division JP2010215615A (ja) | 1997-07-31 | 2010-02-12 | 転移予防のための医薬の製造のためのタウロリジンまたはタウルルタムの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001511463A JP2001511463A (ja) | 2001-08-14 |
| JP2001511463A5 true JP2001511463A5 (OSRAM) | 2006-01-05 |
Family
ID=10816777
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000504921A Pending JP2001511463A (ja) | 1997-07-31 | 1998-07-31 | 転移予防のための医薬の製造のためのタウロリジンまたはタウルルタムの使用 |
| JP2010029152A Pending JP2010215615A (ja) | 1997-07-31 | 2010-02-12 | 転移予防のための医薬の製造のためのタウロリジンまたはタウルルタムの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010029152A Pending JP2010215615A (ja) | 1997-07-31 | 2010-02-12 | 転移予防のための医薬の製造のためのタウロリジンまたはタウルルタムの使用 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1001781B1 (OSRAM) |
| JP (2) | JP2001511463A (OSRAM) |
| AT (1) | ATE318141T1 (OSRAM) |
| DE (1) | DE69833554T2 (OSRAM) |
| ES (1) | ES2255172T3 (OSRAM) |
| GB (1) | GB9716219D0 (OSRAM) |
| WO (1) | WO1999006114A2 (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9626795D0 (en) | 1996-12-23 | 1997-02-12 | Geistlich Soehne Ag | Combating infection in delivery systems |
| US20030027818A1 (en) | 2001-04-03 | 2003-02-06 | Redmond H. Paul | Treatment of cancers |
| US7132413B1 (en) | 1997-07-31 | 2006-11-07 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Anticoagulant/sterilizing compositions and methods |
| US6479481B1 (en) * | 1999-06-04 | 2002-11-12 | Ed. Geistlich Soehne Ag Fur Chemische Industrie | Methods and compositions for treating primary and secondary tumors of the central nervous system (CNS) |
| US8304390B2 (en) | 1997-07-31 | 2012-11-06 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treatment for preventing or reducing tumor growth in the liver of patient |
| CA2302720C (en) * | 1999-03-29 | 2009-07-14 | Ed Geistlich Sohne Ag Fur Chemische Industrie | Anticoagulant/sterilizing compositions and methods |
| US8030301B2 (en) | 1999-06-04 | 2011-10-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of cancers with methylol-containing compounds and at least one electrolyte |
| US7345039B2 (en) | 1999-06-04 | 2008-03-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer |
| US20020098164A1 (en) * | 2000-10-27 | 2002-07-25 | Redmond H. Paul | Treatment of tumor metastases and cancer |
| US7892530B2 (en) | 1999-06-04 | 2011-02-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of tumor metastases and cancer |
| CA2393252A1 (en) | 1999-12-06 | 2001-06-07 | Paul Calabresi | Use of methylol-containing compounds to treat tumors |
| CN100519525C (zh) | 1999-12-06 | 2009-07-29 | 葛兰素集团有限公司 | 芳香砜类及其医疗用途 |
| US6641571B2 (en) | 2000-01-05 | 2003-11-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery |
| CA2363973C (en) * | 2000-11-28 | 2009-03-10 | Ed. Geistlich Sohne Ag Fur Chemische Industrie | Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer |
| US20030092707A1 (en) * | 2001-10-19 | 2003-05-15 | Redmond H. Paul | Treatment of breast cancer |
| WO2003028642A2 (en) * | 2001-10-01 | 2003-04-10 | Rhode Island Hospital, A Lifespan Partner | Methods of inhibiting metastases |
| CA2412012C (en) | 2001-11-20 | 2011-08-02 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage |
| US8236794B2 (en) | 2003-09-29 | 2012-08-07 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of mesothelioma |
| WO2008029264A2 (en) * | 2006-09-07 | 2008-03-13 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treating bone cancer |
| AU2019331913B2 (en) * | 2018-08-31 | 2025-06-26 | Cormedix Inc. | Taurolidine treatment for myc-expressing tumors in mammalian bodies |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6117A (ja) * | 1984-06-11 | 1986-01-06 | Seikagaku Kogyo Co Ltd | ムコ多糖系癌転移抑制剤 |
| GB9015108D0 (en) * | 1990-07-09 | 1990-08-29 | Geistlich Soehne Ag | Chemical compositions |
| CA2122519C (en) * | 1994-04-29 | 2001-02-20 | Rudolf Edgar Dr. Falk | Cancer treatment and metastasis prevention |
| GB9400163D0 (en) * | 1994-01-06 | 1994-03-02 | Geistlich Soehne Ag | Membrane |
| DE19606897C2 (de) * | 1996-02-13 | 2002-08-29 | Geistlich Soehne Ag | Mittel zur Verhinderung der Tumorzellverschleppung und der Entstehung von Trokarmetastasen in der offenen und laparoskopischen Chirurgie maligner Tumoren |
-
1997
- 1997-07-31 GB GBGB9716219.2A patent/GB9716219D0/en active Pending
-
1998
- 1998-07-31 JP JP2000504921A patent/JP2001511463A/ja active Pending
- 1998-07-31 AT AT98937635T patent/ATE318141T1/de active
- 1998-07-31 EP EP98937635A patent/EP1001781B1/en not_active Expired - Lifetime
- 1998-07-31 DE DE69833554T patent/DE69833554T2/de not_active Expired - Lifetime
- 1998-07-31 ES ES98937635T patent/ES2255172T3/es not_active Expired - Lifetime
- 1998-07-31 WO PCT/GB1998/002311 patent/WO1999006114A2/en not_active Ceased
-
2010
- 2010-02-12 JP JP2010029152A patent/JP2010215615A/ja active Pending
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