JP2001510450A - 骨欠損状態を処置するための組成物および方法 - Google Patents
骨欠損状態を処置するための組成物および方法Info
- Publication number
- JP2001510450A JP2001510450A JP51952998A JP51952998A JP2001510450A JP 2001510450 A JP2001510450 A JP 2001510450A JP 51952998 A JP51952998 A JP 51952998A JP 51952998 A JP51952998 A JP 51952998A JP 2001510450 A JP2001510450 A JP 2001510450A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- nrcr
- independently
- bone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73631896A | 1996-10-23 | 1996-10-23 | |
| US73587696A | 1996-10-23 | 1996-10-23 | |
| US73622096A | 1996-10-23 | 1996-10-23 | |
| US73631996A | 1996-10-23 | 1996-10-23 | |
| US73587496A | 1996-10-23 | 1996-10-23 | |
| US73622296A | 1996-10-23 | 1996-10-23 | |
| US73588196A | 1996-10-23 | 1996-10-23 | |
| US73587396A | 1996-10-23 | 1996-10-23 | |
| US73622896A | 1996-10-23 | 1996-10-23 | |
| US73587096A | 1996-10-23 | 1996-10-23 | |
| US73622196A | 1996-10-23 | 1996-10-23 | |
| US08/736,220 | 1996-10-23 | ||
| US08/735,873 | 1996-10-23 | ||
| US08/736,228 | 1996-10-23 | ||
| US08/735,870 | 1996-10-23 | ||
| US08/736,221 | 1996-10-23 | ||
| US08/736,318 | 1996-10-23 | ||
| US08/736,222 | 1996-10-23 | ||
| US08/736,319 | 1996-10-23 | ||
| US08/735,876 | 1996-10-23 | ||
| US08/735,881 | 1996-10-23 | ||
| US08/735,874 | 1996-10-23 | ||
| PCT/US1997/018864 WO1998017267A1 (fr) | 1996-10-23 | 1997-10-23 | Compositions et methodes pour traiter les etats associes a un deficit osseux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2001510450A true JP2001510450A (ja) | 2001-07-31 |
Family
ID=27582807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51952998A Pending JP2001510450A (ja) | 1996-10-23 | 1997-10-23 | 骨欠損状態を処置するための組成物および方法 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0973513A4 (fr) |
| JP (1) | JP2001510450A (fr) |
| AU (1) | AU4988997A (fr) |
| WO (1) | WO1998017267A1 (fr) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006513162A (ja) * | 2002-11-01 | 2006-04-20 | パラテック ファーマシューティカルズ インコーポレイテッド | 転写因子調節化合物およびその使用方法 |
| JP2007535488A (ja) * | 2004-04-30 | 2007-12-06 | 武田薬品工業株式会社 | 複素環アミド化合物及びｍｍｐ−１３阻害剤としてのその用途 |
| JP2010037215A (ja) * | 2008-07-31 | 2010-02-18 | Tokyo Ohka Kogyo Co Ltd | レジスト組成物、レジストパターン形成方法、新規な化合物および光塩基発生剤 |
| WO2012026491A1 (fr) * | 2010-08-26 | 2012-03-01 | 国立大学法人京都大学 | Agent favorisant la différenciation de cellules souches pluripotentes en cardiomyocytes |
| WO2013111875A1 (fr) * | 2012-01-27 | 2013-08-01 | 国立大学法人京都大学 | Procédé d'induction de différenciation myocardique de cellules souches pluripotentes |
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| US6919366B2 (en) | 1998-05-22 | 2005-07-19 | Avanir Pharmaceuticals | Benzimidazole derivatives as modulators of IgE |
| US6303645B1 (en) | 1998-05-22 | 2001-10-16 | Avanir Pharmaceuticals | Benzimidazole derivatives as modulators of IgE |
| DE69919707T2 (de) * | 1998-06-19 | 2005-09-01 | Chiron Corp., Emeryville | Glycogen synthase kinase 3 inhibitoren |
| US6902721B1 (en) | 1998-07-10 | 2005-06-07 | Osteoscreen, Inc. | Inhibitors of proteasomal activity for stimulating bone growth |
| US6462019B1 (en) | 1998-07-10 | 2002-10-08 | Osteoscreen, Inc. | Inhibitors of proteasomal activity and production for stimulating bone growth |
| US6838436B1 (en) | 1998-07-10 | 2005-01-04 | Osteoscreen Inc. | Inhibitors of proteasomal activity for stimulating bone growth |
| ES2377847T3 (es) | 1999-01-13 | 2012-04-02 | Bayer Healthcare Llc | Difenil ureas sustituidas con omega-carboxi arilo como agentes inhibidores de la cinasa p38 |
| US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| DE60037394T2 (de) | 1999-01-29 | 2009-01-02 | The Board Of Trustees For The University Of Illinois, Urbana | VERWENDUNG VON p53 INHIBITOREN ZUR BEHANDLUNG VON NEBENERSCHEINUNGEN BEI DER KREBSTHERAPIE |
| TR200102790T2 (tr) * | 1999-03-26 | 2002-06-21 | Euro-Celtique S.A. | Aril İkameli Pirazoller, İmidazoller, Oksazoller, Tiazoller ve Piroller Ve Bunların Kullanımı. |
| AU5250400A (en) * | 1999-06-18 | 2001-01-09 | Mitsubishi Pharma Corporation | Osteogenesis promoters |
| WO2001017562A1 (fr) * | 1999-09-02 | 2001-03-15 | Yamanouchi Pharmaceutical Co., Ltd. | Agents promoteurs de l'osteogenese |
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| JP5278983B2 (ja) * | 1999-11-17 | 2013-09-04 | 塩野義製薬株式会社 | アミド化合物の新規用途 |
| CA2403605A1 (fr) | 2000-03-31 | 2002-09-18 | Kazuya Mori | Derives et medicaments heterocycliques |
| US7270800B2 (en) | 2000-08-24 | 2007-09-18 | University Of Pittsburgh | Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition |
| JP5022554B2 (ja) * | 2000-08-24 | 2012-09-12 | ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | アルツハイマー病の生前診断ならびにアミロイド沈着物のインビボ画像化および予防に用いるためのチオフラビン誘導体 |
| WO2002072090A1 (fr) | 2001-03-12 | 2002-09-19 | Avanir Pharmaceuticals | Composes de benzimidazole modulateurs de l'ige et inhibiteurs de la proliferation cellulaire |
| TWI245764B (en) | 2001-04-23 | 2005-12-21 | Hank F Kung | Amyloid plaque aggregation inhibitors and diagnostic imaging agents |
| US7405235B2 (en) | 2001-05-04 | 2008-07-29 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
| US6660737B2 (en) | 2001-05-04 | 2003-12-09 | The Procter & Gamble Company | Medicinal uses of hydrazones |
| NZ530580A (en) | 2001-07-27 | 2007-02-23 | Curis Inc | Mediators of hedgehog signaling pathways, compositions and uses related thereto |
| US7429593B2 (en) | 2001-09-14 | 2008-09-30 | Shionogi & Co., Ltd. | Utilities of amide compounds |
| US7064139B2 (en) * | 2001-10-29 | 2006-06-20 | Uniroyal Chemical Company, Inc. | Method for treating retroviral infections |
| UA83620C2 (ru) | 2001-12-05 | 2008-08-11 | Уайт | Замещенные бензоксазолы и их аналоги как эстрогенные агенты |
| SI1478358T1 (sl) | 2002-02-11 | 2013-09-30 | Bayer Healthcare Llc | Sorafenib tozilat za zdravljenje bolezni, značilnih po abnormalni angiogenezi |
| EP1474393A1 (fr) | 2002-02-11 | 2004-11-10 | Bayer Pharmaceuticals Corporation | Aryle-urees en tant qu'inhibiteurs de kinase |
| JP4513566B2 (ja) | 2002-04-26 | 2010-07-28 | 日本新薬株式会社 | キナゾリン誘導体及び医薬 |
| SE0202134D0 (sv) * | 2002-07-08 | 2002-07-08 | Astrazeneca Ab | Therapeutic agents |
| US7247741B2 (en) | 2005-01-21 | 2007-07-24 | Ptc Therapeutics, Inc. | Acetylamino benzoic acid compounds and their use for nonsense suppression and the treatment of disease |
| CA2493457A1 (fr) * | 2002-07-24 | 2004-01-29 | Ptc Therapeutics, Inc. | Composes d'acide acetylamino benzoique et leur utilisation pour la suppression de non-sens et le traitement de maladie |
| TWI276631B (en) | 2002-09-12 | 2007-03-21 | Avanir Pharmaceuticals | Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation |
| AU2003270426A1 (en) | 2002-09-12 | 2004-04-30 | Avanir Pharmaceuticals | PHENYL-INDOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION |
| DK1626714T3 (da) | 2003-05-20 | 2007-10-15 | Bayer Pharmaceuticals Corp | Dirarylurinstoffer mod sygdomme medieret af PDGFR |
| RS52625B (en) | 2003-07-23 | 2013-06-28 | Bayer Healthcare Llc | FLUORO SUBSTITUTED OMEGA-CARBOXYARYL DIPHENYL UREA FOR TREATMENT AND PREVENTION OF DISEASES AND DISEASES |
| US8236282B2 (en) | 2003-08-22 | 2012-08-07 | University of Pittsburgh—of the Commonwealth System of Higher Education | Benzothiazole derivative compounds, compositions and uses |
| FR2860431A1 (fr) * | 2003-10-02 | 2005-04-08 | Oreal | Composition capillaire ou de mascara contenant un compose azoique, son utilisation pour stimuler ou induire la pousse des cheveux ou des cils et/ou freiner leur chute |
| ITTO20040125A1 (it) * | 2004-03-01 | 2004-06-01 | Rotta Research Lab | Nuove amidine eterocicliche inibitrici la produzione di ossido d'azoto (no) ad attivita' antinfiammatoria ed analgesica |
| CA2562763A1 (fr) | 2004-04-23 | 2006-07-20 | Paratek Pharmaceuticals, Inc. | Composes de modulation de facteur de transcription et leurs procedes d'utilisation |
| WO2008060693A2 (fr) * | 2006-05-17 | 2008-05-22 | Cylene Pharmaceuticals, Inc. | Analogues d'imidazole tétracycliques |
| CN102558091B (zh) * | 2011-12-22 | 2014-10-08 | 合肥工业大学 | 一种苯并噻唑类衍生物及其用途 |
| EP3147280B1 (fr) | 2012-07-18 | 2018-03-07 | University College Dublin, National University of Ireland, Dublin | Composé anti-angiogène |
| CN102942515A (zh) * | 2012-10-22 | 2013-02-27 | 暨南大学 | 一种乙烯桥连吲哚化合物及其合成方法和用途 |
| CN106188003B (zh) * | 2016-07-22 | 2019-01-22 | 清华大学深圳研究生院 | 基于喹啉骨架的Cu2+和Fe3+双靶点荧光探针及其制备方法和应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU532512B2 (en) * | 1979-09-07 | 1983-10-06 | Upjohn and Horton | Anti-allergenic compounds for bone mineral resorption |
| US4889851A (en) * | 1986-11-21 | 1989-12-26 | Fujisawa Pharmaceutical Co, Ltd. | Benzothiadiazine compounds, and pharmaceutical composition comprising the same |
| JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
| US5280040A (en) * | 1993-03-11 | 1994-01-18 | Zymogenetics, Inc. | Methods for reducing bone loss using centchroman derivatives |
| US6756388B1 (en) * | 1993-10-12 | 2004-06-29 | Pfizer Inc. | Benzothiophenes and related compounds as estrogen agonists |
| US5441964A (en) * | 1993-10-15 | 1995-08-15 | Eli Lilly And Company | Methods for inhibiting bone loss using substituted benzothiophene |
| US5622974A (en) * | 1995-03-10 | 1997-04-22 | Eli Lilly And Company | α-substituted-3-benzyl-benzofurans |
| US5523309A (en) * | 1995-03-10 | 1996-06-04 | Eli Lilly And Company | Benzofuran pharmaceutical compounds |
| FR2733685B1 (fr) * | 1995-05-05 | 1997-05-30 | Adir | Utilisation des derives du benzopyrane pour l'obtention de compositions pharmaceutiques destinees au traitement des pathologies liees a l'echangeur c1-/hc03-, na+ independant |
| AU706262B2 (en) * | 1995-10-23 | 1999-06-10 | Osteoscreen, Inc. | Compositions and methods for treating bone deficit conditions |
| EP0783888A1 (fr) * | 1995-12-26 | 1997-07-16 | Sankyo Company Limited | Utilisation de la troglitazone et de thiazolidinediones apparentées dans la fabrication d'un médicament destiné au traitement et la prévention de l'ostéoporose |
| PL330814A1 (en) * | 1996-06-20 | 1999-06-07 | Regents Board Of | Compounds for and methods of delivering pharmaceutical preparations and their application |
-
1997
- 1997-10-23 EP EP97912787A patent/EP0973513A4/fr not_active Withdrawn
- 1997-10-23 AU AU49889/97A patent/AU4988997A/en not_active Abandoned
- 1997-10-23 JP JP51952998A patent/JP2001510450A/ja active Pending
- 1997-10-23 WO PCT/US1997/018864 patent/WO1998017267A1/fr not_active Application Discontinuation
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006513162A (ja) * | 2002-11-01 | 2006-04-20 | パラテック ファーマシューティカルズ インコーポレイテッド | 転写因子調節化合物およびその使用方法 |
| JP2007535488A (ja) * | 2004-04-30 | 2007-12-06 | 武田薬品工業株式会社 | 複素環アミド化合物及びｍｍｐ−１３阻害剤としてのその用途 |
| JP4848286B2 (ja) * | 2004-04-30 | 2011-12-28 | 武田薬品工業株式会社 | 複素環アミド化合物及びｍｍｐ−１３阻害剤としてのその用途 |
| JP2010037215A (ja) * | 2008-07-31 | 2010-02-18 | Tokyo Ohka Kogyo Co Ltd | レジスト組成物、レジストパターン形成方法、新規な化合物および光塩基発生剤 |
| US8658425B2 (en) | 2010-08-26 | 2014-02-25 | Kyoto University | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells |
| WO2012026491A1 (fr) * | 2010-08-26 | 2012-03-01 | 国立大学法人京都大学 | Agent favorisant la différenciation de cellules souches pluripotentes en cardiomyocytes |
| JP5930205B2 (ja) * | 2010-08-26 | 2016-06-08 | 国立大学法人京都大学 | 多能性幹細胞の心筋分化促進剤 |
| US9499790B2 (en) | 2010-08-26 | 2016-11-22 | Kyoto University | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells |
| WO2013111875A1 (fr) * | 2012-01-27 | 2013-08-01 | 国立大学法人京都大学 | Procédé d'induction de différenciation myocardique de cellules souches pluripotentes |
| JPWO2013111875A1 (ja) * | 2012-01-27 | 2015-05-11 | 国立大学法人京都大学 | 多能性幹細胞の心筋分化誘導法 |
| US9587220B2 (en) | 2012-01-27 | 2017-03-07 | Kyoto University | Method for inducing cardiac differentiation of pluripotent stem cell |
| US10196609B2 (en) | 2013-03-08 | 2019-02-05 | Kyoto University | Composition for promoting cardiac differentiation of pluripotent stem cell comprising EGFR inhibitor |
| US10233426B2 (en) | 2014-05-30 | 2019-03-19 | Kyoto University | Method for inducing cardiac differentiation of pluripotent stem cell with low-molecular compounds |
| JP7558210B2 (ja) | 2019-06-26 | 2024-09-30 | ユーシービー バイオファルマ エスアールエル | Ｉｌ－１７調節剤としての縮合イミダゾール誘導体 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0973513A1 (fr) | 2000-01-26 |
| EP0973513A4 (fr) | 2003-03-19 |
| WO1998017267A1 (fr) | 1998-04-30 |
| AU4988997A (en) | 1998-05-15 |
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