|
IL121860A0
(en)
|
1997-08-14 |
1998-02-22 |
Yeda Res & Dev |
Interleukin-18 binding proteins their preparation and use
|
|
US7220717B2
(en)
|
1997-08-14 |
2007-05-22 |
Yeda Research And Development Company Ltd. |
Interleukin-18 binding proteins, their preparation and use
|
|
US7704944B2
(en)
|
1997-08-14 |
2010-04-27 |
Yeda Research And Development Company Ltd. |
Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis
|
|
FR2781483A1
(fr)
*
|
1998-07-21 |
2000-01-28 |
Hoechst Marion Roussel Inc |
Derives de thioazepinone, procede de preparation et intermediaires de ce procede, application a titre de medicament et compositions pharmaceutiques les renfermant
|
|
US7015212B1
(en)
|
1999-05-12 |
2006-03-21 |
The United States Of America As Represented By The Department Of Health And Human Services |
Thiazepine inhibitors of HIV-1 integrase
|
|
HU229164B1
(en)
*
|
2001-01-29 |
2013-09-30 |
Serono Sa Coinsins Lab |
Use of il-18 inhibitors for the treatment and/or prevention of heart disease
|
|
WO2002066063A1
(en)
*
|
2001-02-23 |
2002-08-29 |
Nippon Organon K.K. |
Remedies for metabolic bone diseases
|
|
US7001899B2
(en)
*
|
2002-06-10 |
2006-02-21 |
The Procter & Gamble Company |
Interleukin converting enzyme inhibitors
|
|
WO2004003142A2
(en)
|
2002-06-28 |
2004-01-08 |
Xcyte Therapies, Inc. |
Compositions and methods for restoring immune repertoire in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
DK1585546T3
(da)
*
|
2002-12-30 |
2008-12-08 |
Biogen Idec Inc |
KIM- 1- Antagonister og Brug til at Modulere Immunsystem
|
|
MXPA06013256A
(es)
*
|
2004-05-15 |
2007-02-08 |
Vertex Pharma |
Tratamiento de crisis convulsivas utilizando inhibidores ice.
|
|
US9512125B2
(en)
*
|
2004-11-19 |
2016-12-06 |
The Regents Of The University Of California |
Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents
|
|
EP2251037B1
(en)
|
2005-03-02 |
2015-01-14 |
Biogen Idec MA Inc. |
KIM-1 antibodies for treatment of TH1/TH2-mediated conditions
|
|
WO2007114926A2
(en)
|
2006-04-04 |
2007-10-11 |
The Regents Of The University Of California |
Kinase antagonists
|
|
GB2467670B
(en)
|
2007-10-04 |
2012-08-01 |
Intellikine Inc |
Chemical entities and therapeutic uses thereof
|
|
EP3613743B1
(en)
|
2008-01-04 |
2022-03-16 |
Intellikine, LLC |
Processes for the preparation of 1h-pyrazolo[3,4-d]pyrimidin-4-amine derivatives
|
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
|
US8993580B2
(en)
|
2008-03-14 |
2015-03-31 |
Intellikine Llc |
Benzothiazole kinase inhibitors and methods of use
|
|
US8637542B2
(en)
*
|
2008-03-14 |
2014-01-28 |
Intellikine, Inc. |
Kinase inhibitors and methods of use
|
|
US20110224223A1
(en)
*
|
2008-07-08 |
2011-09-15 |
The Regents Of The University Of California, A California Corporation |
MTOR Modulators and Uses Thereof
|
|
JP5788316B2
(ja)
*
|
2008-07-08 |
2015-09-30 |
インテリカイン， エルエルシー |
キナーゼインヒビターおよび使用方法
|
|
US8703778B2
(en)
|
2008-09-26 |
2014-04-22 |
Intellikine Llc |
Heterocyclic kinase inhibitors
|
|
WO2010045542A2
(en)
|
2008-10-16 |
2010-04-22 |
The Regents Of The University Of California |
Fused ring heteroaryl kinase inhibitors
|
|
BRPI0914035A2
(pt)
*
|
2008-10-17 |
2015-11-03 |
Koninkl Philips Electronics Nv |
ventilador e método para ventilar um paciente usando um ventilador
|
|
US8476431B2
(en)
|
2008-11-03 |
2013-07-02 |
Itellikine LLC |
Benzoxazole kinase inhibitors and methods of use
|
|
EP2427195B1
(en)
|
2009-05-07 |
2019-05-01 |
Intellikine, LLC |
Heterocyclic compounds and uses thereof
|
|
US8980899B2
(en)
|
2009-10-16 |
2015-03-17 |
The Regents Of The University Of California |
Methods of inhibiting Ire1
|
|
CA2799579A1
(en)
|
2010-05-21 |
2011-11-24 |
Intellikine, Inc. |
Chemical compounds, compositions and methods for kinase modulation
|
|
MX2013004655A
(es)
|
2010-10-26 |
2013-08-27 |
Presidio Pharmaceuticals Inc |
Inhibidores del virus de la hepatitis c.
|
|
JP2013545749A
(ja)
|
2010-11-10 |
2013-12-26 |
インフィニティー ファーマシューティカルズ， インコーポレイテッド |
複素環化合物及びその使用
|
|
TWI674262B
(zh)
|
2011-01-10 |
2019-10-11 |
美商英菲尼提製藥股份有限公司 |
製備異喹啉酮之方法及異喹啉酮之固體形式
|
|
US9295673B2
(en)
|
2011-02-23 |
2016-03-29 |
Intellikine Llc |
Combination of mTOR inhibitors and P13-kinase inhibitors, and uses thereof
|
|
WO2013012915A1
(en)
|
2011-07-19 |
2013-01-24 |
Infinity Pharmaceuticals Inc. |
Heterocyclic compounds and uses thereof
|
|
MX2014000648A
(es)
|
2011-07-19 |
2014-09-25 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos y sus usos.
|
|
US9956260B1
(en)
|
2011-07-22 |
2018-05-01 |
The J. David Gladstone Institutes |
Treatment of HIV-1 infection and AIDS
|
|
KR20140075693A
(ko)
|
2011-08-29 |
2014-06-19 |
인피니티 파마슈티칼스, 인코포레이티드 |
헤테로사이클릭 화합물 및 그의 용도
|
|
MX370814B
(es)
|
2011-09-02 |
2020-01-08 |
Univ California |
Pirazolo[3,4-d]pirimidinas sustituidas y usos de las mismas.
|
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
US8828998B2
(en)
|
2012-06-25 |
2014-09-09 |
Infinity Pharmaceuticals, Inc. |
Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
|
|
MX2015003874A
(es)
|
2012-09-26 |
2015-12-16 |
Univ California |
Modulacion de ire1.
|
|
EP2914296B2
(en)
|
2012-11-01 |
2021-09-29 |
Infinity Pharmaceuticals, Inc. |
Treatment of cancers using pi3 kinase isoform modulators
|
|
US9481667B2
(en)
|
2013-03-15 |
2016-11-01 |
Infinity Pharmaceuticals, Inc. |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
|
WO2015051241A1
(en)
|
2013-10-04 |
2015-04-09 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
MX2021012208A
(es)
|
2013-10-04 |
2023-01-19 |
Infinity Pharmaceuticals Inc |
Compuestos heterocíclicos y usos de los mismos.
|
|
CN103804367B
(zh)
*
|
2014-02-28 |
2016-09-14 |
天津药物研究院 |
苯并氮杂卓衍生物、其制备方法和用途
|
|
NZ724368A
(en)
|
2014-03-19 |
2023-07-28 |
Infinity Pharmaceuticals Inc |
Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders
|
|
WO2015160975A2
(en)
|
2014-04-16 |
2015-10-22 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
|
WO2016054491A1
(en)
|
2014-10-03 |
2016-04-07 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
TWI763630B
(zh)
|
2015-07-02 |
2022-05-11 |
瑞士商赫孚孟拉羅股份公司 |
雙環內醯胺及其使用方法
|
|
EP4585268A3
(en)
|
2015-09-14 |
2025-10-15 |
Twelve Therapeutics, Inc. |
Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same
|
|
MA44007A
(fr)
|
2016-02-05 |
2018-12-19 |
Denali Therapeutics Inc |
Inhibiteurs du récepteur interagissant avec protéine kinase 1
|
|
US10759806B2
(en)
|
2016-03-17 |
2020-09-01 |
Infinity Pharmaceuticals, Inc. |
Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as PI3K kinase inhibitors
|
|
WO2017214269A1
(en)
|
2016-06-08 |
2017-12-14 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
RU2754507C2
(ru)
|
2016-06-24 |
2021-09-02 |
Инфинити Фармасьютикалз, Инк. |
Комбинированная терапия
|
|
EP3526219B1
(en)
|
2016-10-17 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Bicyclic pyridone lactams and methods of use thereof
|
|
HRP20220636T1
(hr)
|
2016-12-09 |
2022-07-22 |
Denali Therapeutics Inc. |
Spojevi korisni kao inhibitori ripk1
|
|
US11072607B2
(en)
|
2016-12-16 |
2021-07-27 |
Genentech, Inc. |
Inhibitors of RIP1 kinase and methods of use thereof
|
|
WO2019204537A1
(en)
|
2018-04-20 |
2019-10-24 |
Genentech, Inc. |
N-[4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-5,6-dihydro-4h-pyrrolo[1,2-b]pyrazol e-2-carboxamide derivatives and related compounds as rip1 kinase inhibitors for treating e.g. irritable bowel syndrome (ibs)
|
|
IL314082A
(en)
|
2022-01-12 |
2024-09-01 |
Denali Therapeutics Inc |
Crystal forms of (S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydropyrido[3,2-b][1,4]oxazapin-3-yl)- H4- 1,2,4-triazole-3-carboxamide
|