|
US5674908A
(en)
|
1993-12-20 |
1997-10-07 |
Life Technologies, Inc. |
Highly packed polycationic ammonium, sulfonium and phosphonium lipids
|
|
US6989434B1
(en)
|
1994-02-11 |
2006-01-24 |
Invitrogen Corporation |
Reagents for intracellular delivery of macromolecules
|
|
DE69735382T2
(de)
*
|
1996-11-04 |
2006-11-30 |
Qiagen Gmbh |
Kationische reagenzien zür transfektion
|
|
NZ512244A
(en)
|
1998-11-12 |
2003-12-19 |
Invitrogen Corp |
Polycationic transfection reagents for introducing anions into a cell
|
|
US7683035B1
(en)
*
|
1999-02-23 |
2010-03-23 |
Qiagen, Gmbh |
Method of stabilizing and/or isolating nucleic acids
|
|
US20030096414A1
(en)
|
2001-03-27 |
2003-05-22 |
Invitrogen Corporation |
Culture medium for cell growth and transfection
|
|
EP1638919B1
(en)
*
|
2003-06-18 |
2012-09-26 |
Biolab Ltd. |
Sphingolipids polyalkylamines conjugates
|
|
US7906122B2
(en)
|
2003-06-18 |
2011-03-15 |
Yissum Research Development Company Of The Hebrew University Of Jersusalem |
Sphingoid polyalkylamine conjugates for Hepatitis B virus vaccination
|
|
US20060211004A1
(en)
|
2005-02-15 |
2006-09-21 |
Ilsley Diane D |
Methods and compositions for determining non-specific cytotoxicity of a transfection agent
|
|
US20060257858A1
(en)
*
|
2005-04-01 |
2006-11-16 |
Invitrogen Corporation |
Methods and compositions for introducing biopolymers into cells
|
|
NZ569541A
(en)
|
2006-01-13 |
2012-05-25 |
Us Gov Health & Human Serv |
Codon optimized IL-15 and IL-15R-alpha genes for expression in mammalian cells
|
|
HUE040417T2
(hu)
|
2007-05-04 |
2019-03-28 |
Marina Biotech Inc |
Aminosavlipidek és alkalmazásuk
|
|
WO2009155100A1
(en)
|
2008-05-30 |
2009-12-23 |
Yale University |
Targeted oligonucleotide compositions for modifying gene expression
|
|
JP2012505913A
(ja)
|
2008-10-16 |
2012-03-08 |
マリーナ バイオテック,インコーポレイテッド |
遺伝子発現を抑制する治療におけるリポソームによる効率的な送達のプロセスおよび組成物
|
|
EP3318248B1
(en)
|
2009-12-01 |
2019-04-10 |
Translate Bio, Inc. |
Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
|
|
US20130052221A1
(en)
|
2010-02-26 |
2013-02-28 |
The Govt. of the U.S, as represented by The Sec. of The Dept. of Health and Human Services |
Dna-protein vaccination protocols
|
|
WO2011120023A1
(en)
|
2010-03-26 |
2011-09-29 |
Marina Biotech, Inc. |
Nucleic acid compounds for inhibiting survivin gene expression uses thereof
|
|
WO2011133584A2
(en)
|
2010-04-19 |
2011-10-27 |
Marina Biotech, Inc. |
Nucleic acid compounds for inhibiting hras gene expression and uses thereof
|
|
WO2011139843A2
(en)
|
2010-04-28 |
2011-11-10 |
Marina Biotech, Inc. |
Multi-sirna compositions for reducing gene expression
|
|
FR2964569B1
(fr)
|
2010-09-10 |
2012-10-19 |
Ct De Cooperation Internationale En Rech Agronomique Pour Le Dev Cirad |
Nouveaux liposomes de vaccination genique
|
|
US8853377B2
(en)
|
2010-11-30 |
2014-10-07 |
Shire Human Genetic Therapies, Inc. |
mRNA for use in treatment of human genetic diseases
|
|
NZ703649A
(en)
|
2010-12-06 |
2016-08-26 |
Penn State Res Found |
Compositions and methods relating to proliferative diseases
|
|
RU2013154295A
(ru)
|
2011-06-08 |
2015-07-20 |
Шир Хьюман Дженетик Терапис, Инк. |
КОМПОЗИЦИИ ЛИПИДНЫХ НАНОЧАСТИЦ И СПОСОБЫ ДЛЯ ДОСТАВКИ мРНК
|
|
ES2567091T3
(es)
*
|
2012-04-05 |
2016-04-19 |
F. Hoffmann-La Roche Ag |
Compuestos de amina para la preparación selectiva de muestras biológicas
|
|
WO2013185067A1
(en)
|
2012-06-08 |
2013-12-12 |
Shire Human Genetic Therapies, Inc. |
Nuclease resistant polynucleotides and uses thereof
|
|
RS57739B1
(sr)
|
2013-03-14 |
2018-12-31 |
Translate Bio Inc |
Kompozicije cftr irnk i postupci i upotrebe u vezi sa njima
|
|
JP6586075B2
(ja)
|
2013-03-14 |
2019-10-02 |
トランスレイト バイオ, インコーポレイテッド |
メッセンジャーrnaの精製方法
|
|
WO2014142995A1
(en)
|
2013-03-15 |
2014-09-18 |
The Penn State Research Foundation |
Compositions and methods including leelamine and arachidonyl trifluoromethyl ketone relating to treatment of cancer
|
|
AU2013381866A1
(en)
|
2013-03-15 |
2015-09-24 |
The Penn State Research Foundation |
Compositions and methods including celecoxib and plumbagin relating to treatment of cancer
|
|
JP6506749B2
(ja)
|
2013-10-22 |
2019-04-24 |
シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド |
フェニルケトン尿症のためのmRNA療法
|
|
CN106413811A
(zh)
|
2013-10-22 |
2017-02-15 |
夏尔人类遗传性治疗公司 |
精氨基琥珀酸合成酶缺乏症的mrna疗法
|
|
US9850269B2
(en)
|
2014-04-25 |
2017-12-26 |
Translate Bio, Inc. |
Methods for purification of messenger RNA
|
|
EP3169310A1
(en)
|
2014-07-15 |
2017-05-24 |
Life Technologies Corporation |
Compositions with lipid aggregates and methods for efficient delivery of molecules to cells
|
|
EA201991747A1
(ru)
|
2017-02-27 |
2020-06-04 |
Транслейт Био, Инк. |
НОВАЯ КОДОН-ОПТИМИЗИРОВАННАЯ мРНК CFTR
|
|
MX2019013752A
(es)
|
2017-05-16 |
2020-07-20 |
Translate Bio Inc |
Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr optimizado en codones.
|
|
KR102950141B1
(ko)
|
2018-08-24 |
2026-04-07 |
트랜슬레이트 바이오 인코포레이티드 |
전령 rna의 정제 방법
|
|
WO2020106946A1
(en)
|
2018-11-21 |
2020-05-28 |
Translate Bio, Inc. |
TREATMENT OF CYSTIC FIBROSIS BY DELIVERY OF NEBULIZED mRNA ENCODING CFTR
|
|
WO2020219531A1
(en)
|
2019-04-22 |
2020-10-29 |
The Penn State Research Foundation |
Methods and compositions relating to inhibition of aldehyde dehydrogenases for treatment of cancer
|
|
EP4031662A1
(en)
|
2019-09-20 |
2022-07-27 |
Translate Bio, Inc. |
Mrna encoding engineered cftr
|
|
CN114656422B
(zh)
*
|
2022-04-22 |
2023-05-23 |
重庆理工大学 |
一种新型氮杂冠醚化合物及其阳离子脂质体、制备方法与应用
|
|
US20230392188A1
(en)
|
2022-06-02 |
2023-12-07 |
Perkinelmer Health Sciences, Inc. |
Electrophoresis-mediated characterization of dna content of adeno-associated virus capsids
|