JP2001503751A5 - - Google Patents

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Publication number
JP2001503751A5
JP2001503751A5 JP1998520843A JP52084398A JP2001503751A5 JP 2001503751 A5 JP2001503751 A5 JP 2001503751A5 JP 1998520843 A JP1998520843 A JP 1998520843A JP 52084398 A JP52084398 A JP 52084398A JP 2001503751 A5 JP2001503751 A5 JP 2001503751A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998520843A
Other languages
English (en)
Japanese (ja)
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JP4175667B2 (ja
JP2001503751A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP1997/006035 external-priority patent/WO1998019709A2/en
Publication of JP2001503751A publication Critical patent/JP2001503751A/ja
Publication of JP2001503751A5 publication Critical patent/JP2001503751A5/ja
Application granted granted Critical
Publication of JP4175667B2 publication Critical patent/JP4175667B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP52084398A 1996-11-04 1997-11-03 トランスフェクションのためのカチオン試薬 Expired - Lifetime JP4175667B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3031596P 1996-11-04 1996-11-04
US60/030,315 1996-11-04
PCT/EP1997/006035 WO1998019709A2 (en) 1996-11-04 1997-11-03 Cationic reagents for transfection

Publications (3)

Publication Number Publication Date
JP2001503751A JP2001503751A (ja) 2001-03-21
JP2001503751A5 true JP2001503751A5 (enExample) 2005-03-10
JP4175667B2 JP4175667B2 (ja) 2008-11-05

Family

ID=21853640

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52084398A Expired - Lifetime JP4175667B2 (ja) 1996-11-04 1997-11-03 トランスフェクションのためのカチオン試薬

Country Status (7)

Country Link
US (2) US6733777B2 (enExample)
EP (1) EP1003556B1 (enExample)
JP (1) JP4175667B2 (enExample)
AU (1) AU738384B2 (enExample)
CA (1) CA2270396C (enExample)
DE (1) DE69735382T2 (enExample)
WO (1) WO1998019709A2 (enExample)

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US7906122B2 (en) 2003-06-18 2011-03-15 Yissum Research Development Company Of The Hebrew University Of Jersusalem Sphingoid polyalkylamine conjugates for Hepatitis B virus vaccination
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WO2006110358A2 (en) * 2005-04-01 2006-10-19 Invitrogen Corporation Methods and compositions for introducing biopolymers into cells
EP2366787B1 (en) 2006-01-13 2019-12-11 The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services Codon optimized IL-15 and IL-15R-Alpha genes for expression in mammalian cells
EP3434259A1 (en) 2007-05-04 2019-01-30 Marina Biotech, Inc. Amino acid lipids and uses thereof
US20110212021A1 (en) 2008-05-30 2011-09-01 Slack Frank J Targeted oligonucleotide compositions for modifying gene expression
CN104382853A (zh) 2008-10-16 2015-03-04 玛瑞纳生物技术有限公司 基因沉默治疗剂的脂质体有效递送方法和组合物
SI2506857T1 (en) 2009-12-01 2018-08-31 Translate Bio, Inc. Delivery of mRNA for the enrichment of proteins and enzymes in human genetic diseases
WO2011106705A2 (en) 2010-02-26 2011-09-01 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Dna-protein vaccination protocols
WO2011120023A1 (en) 2010-03-26 2011-09-29 Marina Biotech, Inc. Nucleic acid compounds for inhibiting survivin gene expression uses thereof
WO2011133584A2 (en) 2010-04-19 2011-10-27 Marina Biotech, Inc. Nucleic acid compounds for inhibiting hras gene expression and uses thereof
WO2011139842A2 (en) 2010-04-28 2011-11-10 Marina Biotech, Inc. Nucleic acid compounds for inhibiting fgfr3 gene expression and uses thereof
FR2964569B1 (fr) 2010-09-10 2012-10-19 Ct De Cooperation Internationale En Rech Agronomique Pour Le Dev Cirad Nouveaux liposomes de vaccination genique
US8853377B2 (en) 2010-11-30 2014-10-07 Shire Human Genetic Therapies, Inc. mRNA for use in treatment of human genetic diseases
EP2648706A4 (en) 2010-12-06 2014-07-23 Penn State Res Found COMPOSITIONS AND METHODS RELATING TO PROLIFERATIVE DISEASES
KR20220025112A (ko) 2011-06-08 2022-03-03 샤이어 휴먼 지네틱 테라피즈 인크. Mrna 전달을 위한 지질 나노입자 조성물 및 방법
ES2567091T3 (es) 2012-04-05 2016-04-19 F. Hoffmann-La Roche Ag Compuestos de amina para la preparación selectiva de muestras biológicas
EP3536787A1 (en) 2012-06-08 2019-09-11 Translate Bio, Inc. Nuclease resistant polynucleotides and uses thereof
EA201591229A1 (ru) 2013-03-14 2016-01-29 Шир Хьюман Дженетик Терапис, Инк. Способы очистки матричной рнк
KR102311614B1 (ko) 2013-03-14 2021-10-08 샤이어 휴먼 지네틱 테라피즈 인크. Cftr mrna 조성물 및 관련 방법 및 사용
CA2905649A1 (en) 2013-03-15 2014-09-18 The Penn State Research Foundation Compositions and methods including celecoxib and plumbagin relating to treatment of cancer
EP2968216A1 (en) 2013-03-15 2016-01-20 The Penn State Research Foundation Compositions and methods including leelamine and arachidonyl trifluoromethyl ketone relating to treatment of cancer
EP3574923A1 (en) 2013-10-22 2019-12-04 Translate Bio, Inc. Mrna therapy for phenylketonuria
ES2707966T3 (es) 2013-10-22 2019-04-08 Translate Bio Inc Terapia de ARNm para la deficiencia en síntesis de argininosuccinato
EP4729528A3 (en) 2014-04-25 2026-06-24 Translate Bio, Inc. Methods for purification of messenger rna
US10195280B2 (en) 2014-07-15 2019-02-05 Life Technologies Corporation Compositions and methods for efficient delivery of molecules to cells
MX2019010155A (es) 2017-02-27 2020-12-10 Translate Bio Inc Arnm de cftr optimizado por codón novedoso.
IL270631B2 (en) 2017-05-16 2024-03-01 Translate Bio Inc Treatment of cystic fibrosis by delivery of codon-optimized mrna encoding cftr
US11174500B2 (en) 2018-08-24 2021-11-16 Translate Bio, Inc. Methods for purification of messenger RNA
AU2019384557B2 (en) 2018-11-21 2025-07-17 Translate Bio, Inc. Treatment of cystic fibrosis by delivery of nebulized mRNA encoding CFTR
US20220175723A1 (en) 2019-04-22 2022-06-09 The Penn State Research Foundation Methods and compositions relating to inhibition of aldehyde dehydrogenases for treatment of cancer
CA3155003A1 (en) 2019-09-20 2021-03-25 Translate Bio, Inc. Mrna encoding engineered cftr
US12616678B2 (en) 2020-06-10 2026-05-05 The Penn State Research Foundation Methods to of aldehyde dehydrogenases for treatment of cancer
CN114656422B (zh) * 2022-04-22 2023-05-23 重庆理工大学 一种新型氮杂冠醚化合物及其阳离子脂质体、制备方法与应用
CN119301272A (zh) 2022-06-02 2025-01-10 瑞孚迪健康科学公司 腺相关病毒衣壳的dna含量的电泳介导的表征

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US4022833A (en) * 1973-02-14 1977-05-10 Sterling Drug Inc. N,N'-bridged-bis[2-alkyl-2-hydroxyethylamines]
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US5744335A (en) * 1995-09-19 1998-04-28 Mirus Corporation Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein
US5780448A (en) * 1995-11-07 1998-07-14 Ottawa Civic Hospital Loeb Research DNA-based vaccination of fish
AU738384B2 (en) * 1996-11-04 2001-09-20 Qiagen Gmbh Cationic reagents for transfection

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