JP2001503028A - 内皮損傷の治療方法 - Google Patents
内皮損傷の治療方法Info
- Publication number
- JP2001503028A JP2001503028A JP10513794A JP51379498A JP2001503028A JP 2001503028 A JP2001503028 A JP 2001503028A JP 10513794 A JP10513794 A JP 10513794A JP 51379498 A JP51379498 A JP 51379498A JP 2001503028 A JP2001503028 A JP 2001503028A
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- Prior art keywords
- endothelial
- chemotherapeutic agent
- erythropoietin
- epo
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
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| PCT/US1997/015966 WO1998010650A1 (en) | 1996-09-11 | 1997-09-10 | Method of treating endothelial injury |
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| JP2008048009A Division JP2008133305A (ja) | 1996-09-11 | 2008-02-28 | 内皮細胞の阻止作用を強化する薬剤 |
| JP2009086240A Division JP2009196999A (ja) | 1996-09-11 | 2009-03-31 | 内皮細胞の損傷を減らす薬剤 |
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| JP2008048009A Pending JP2008133305A (ja) | 1996-09-11 | 2008-02-28 | 内皮細胞の阻止作用を強化する薬剤 |
| JP2009086240A Pending JP2009196999A (ja) | 1996-09-11 | 2009-03-31 | 内皮細胞の損傷を減らす薬剤 |
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| JP2008048009A Pending JP2008133305A (ja) | 1996-09-11 | 2008-02-28 | 内皮細胞の阻止作用を強化する薬剤 |
| JP2009086240A Pending JP2009196999A (ja) | 1996-09-11 | 2009-03-31 | 内皮細胞の損傷を減らす薬剤 |
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| US (5) | US20020052309A1 (https=) |
| EP (1) | EP0933995B8 (https=) |
| JP (3) | JP2001503028A (https=) |
| CN (2) | CN1113669C (https=) |
| AT (1) | ATE282425T1 (https=) |
| CA (1) | CA2265547C (https=) |
| DE (1) | DE69731652T2 (https=) |
| DK (1) | DK0933995T3 (https=) |
| ES (1) | ES2231889T3 (https=) |
| PT (1) | PT933995E (https=) |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2007510734A (ja) * | 2003-11-07 | 2007-04-26 | ザ ヘンリー エム． ジャクソン ファウンデイション | 低酸素誘導性遺伝子発現の活性化 |
| WO2008050836A1 (en) * | 2006-10-25 | 2008-05-02 | Ajinomoto Co., Inc. | Agent for ameliorating adverse side-effect of chemotherapeutic agent |
Families Citing this family (31)
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| FR2686899B1 (fr) * | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
| IL124015A0 (en) * | 1998-04-08 | 1999-01-26 | Yeda Res & Dev | Pharmaceutical compositions comprising a protein |
| FR2786104B1 (fr) * | 1998-11-25 | 2002-12-27 | Centre Nat Rech Scient | Inhibiteurs de l'activation de nf-kb, et leurs utilisations pharmaceutiques |
| AU784550B2 (en) * | 1999-04-13 | 2006-05-04 | Kenneth S. Warren Institute, Inc., The | Modulation of excitable tissue function by peripherally administered erythropoietin |
| US7345019B1 (en) * | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
| US7410941B1 (en) | 1999-04-13 | 2008-08-12 | The Kenneth S. Warren Institute, Inc. | Methods for treatment of neurodegenerative conditions by peripherally administered erythropoietin |
| US6171620B1 (en) | 1999-04-27 | 2001-01-09 | Health Research, Inc. | Method of enhancing the efficacy of anti-tumor agents |
| US6747002B2 (en) * | 1999-05-11 | 2004-06-08 | Ortho-Mcneil Pharmaceutical, Inc. | Pharmacokinetic and pharmacodynamic modeling of erythropoietin administration |
| US20030152562A1 (en) * | 2001-10-23 | 2003-08-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Vitro micro-organs, and uses related thereto |
| AU775373B2 (en) | 1999-10-01 | 2004-07-29 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| EP2206720A1 (en) | 2000-04-12 | 2010-07-14 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| AU2001254625B2 (en) * | 2000-05-02 | 2006-02-02 | Action Pharma A/S | Use of alpha-MSH and EPO for preventing or treating ischemic conditions |
| US20020061849A1 (en) * | 2000-05-02 | 2002-05-23 | Soren Nielsen | Methods for treatment of diseases associated with inflammation under non-ischemic conditions |
| US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
| US7767643B2 (en) | 2000-12-29 | 2010-08-03 | The Kenneth S. Warren Institute, Inc. | Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs |
| US20020169128A1 (en) * | 2001-04-09 | 2002-11-14 | Geroge Sigounas | Erythropoietin ameliorates chemotherapy-induced toxicity in vivo |
| EP1930023A3 (en) * | 2001-04-09 | 2008-08-06 | East Carolina University | Erythropoietin ameliorates chemotherapy-induced toxicity in vivo |
| WO2002097038A2 (en) * | 2001-05-25 | 2002-12-05 | Human Genome Sciences, Inc. | Chemokine beta-1 fusion proteins |
| EP1459762B1 (en) * | 2001-11-02 | 2008-07-02 | Yoshiko Yasuda | Use of emp9 for the prevention of proliferative organ diseases |
| EP2261250B1 (en) | 2001-12-21 | 2015-07-01 | Human Genome Sciences, Inc. | GCSF-Albumin fusion proteins |
| GB0211578D0 (en) * | 2002-05-21 | 2002-06-26 | Univ Belfast | Medicaments |
| DE10234192B4 (de) * | 2002-07-26 | 2009-11-26 | Epoplus Gmbh Co.Kg | Verwendung von Erythropoetin |
| CA2513213C (en) | 2003-01-22 | 2013-07-30 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| BRPI0414887A (pt) * | 2003-09-29 | 2006-12-12 | Warren Pharmaceuticals Inc E T | métodos de tratamento, prevenção, retardo do inìcio ou redução dos efeitos de citocinas pró-inflamatórias em um mamìfero e de tratamento, prevenção, retardo do inìcio de uma condição associada com um efeito de citocinas pró-inflamatórias em um mamìfero, e, composição farmacêutica |
| DE102004063927A1 (de) * | 2004-01-23 | 2005-12-15 | Epoplus Gmbh Co.Kg | Einsatz von niedrig dosiertem Erythropoietin zur Stimulation endothelialer Vorläuferzellen sowie zur Organregeneration und Progressionsverlangsamung von Endorganschäden |
| WO2005099773A1 (en) * | 2004-04-05 | 2005-10-27 | University Of Vermont And State Agricultural College | Use of erythropoietin for treatment of cancer |
| US20110076255A1 (en) * | 2005-11-07 | 2011-03-31 | Pecora Andrew L | Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency |
| RU2426174C1 (ru) * | 2010-03-29 | 2011-08-10 | Государственное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" | Способ фармакологической коррекции ишемии конечности, в том числе при l-name индуцированном дефиците оксида азота |
| US9533010B2 (en) * | 2011-10-31 | 2017-01-03 | Amorcyte, Llc | Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency |
| PT2970493T (pt) | 2013-03-15 | 2019-06-27 | Univ Leland Stanford Junior | Métodos para obter doses terapeuticamente eficazes de agentes anti-cd47 |
| EP4340865A4 (en) * | 2021-05-18 | 2025-04-02 | Attias, Eyal | USE OF ERYTHROPOIETIN (EPO) OR ERYTHROPOIESIS STIMULATING AGENT (ESA) FOR THE TREATMENT OF OSTEOMYELITIS, BONE INFECTION AND BONE INFLAMMATION |
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| JPS6045849B2 (ja) * | 1980-08-25 | 1985-10-12 | 林原 健 | ヒトエリトロポエチンの製造方法 |
| US4745099A (en) * | 1985-02-06 | 1988-05-17 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition for the treatment of the anemia of malignant tumors |
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1997
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- 1997-09-10 WO PCT/US1997/015966 patent/WO1998010650A1/en not_active Ceased
- 1997-09-10 JP JP10513794A patent/JP2001503028A/ja not_active Withdrawn
- 1997-09-10 DK DK97940974T patent/DK0933995T3/da active
- 1997-09-10 CA CA002265547A patent/CA2265547C/en not_active Expired - Fee Related
- 1997-09-10 DE DE69731652T patent/DE69731652T2/de not_active Expired - Lifetime
- 1997-09-10 AT AT97940974T patent/ATE282425T1/de active
- 1997-09-10 EP EP97940974A patent/EP0933995B8/en not_active Revoked
- 1997-09-10 PT PT97940974T patent/PT933995E/pt unknown
- 1997-09-10 ES ES97940974T patent/ES2231889T3/es not_active Expired - Lifetime
- 1997-09-10 CN CN97199338A patent/CN1113669C/zh not_active Expired - Fee Related
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2000
- 2000-03-15 US US09/525,797 patent/US7531501B1/en not_active Expired - Fee Related
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2002
- 2002-11-12 CN CNB021506884A patent/CN1250281C/zh not_active Expired - Fee Related
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2007
- 2007-06-29 US US11/771,470 patent/US7803408B2/en not_active Expired - Fee Related
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2008
- 2008-02-28 JP JP2008048009A patent/JP2008133305A/ja active Pending
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2009
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2007510734A (ja) * | 2003-11-07 | 2007-04-26 | ザ ヘンリー エム． ジャクソン ファウンデイション | 低酸素誘導性遺伝子発現の活性化 |
| WO2008050836A1 (en) * | 2006-10-25 | 2008-05-02 | Ajinomoto Co., Inc. | Agent for ameliorating adverse side-effect of chemotherapeutic agent |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0933995A4 (en) | 2002-08-28 |
| CN1235512A (zh) | 1999-11-17 |
| DK0933995T3 (da) | 2005-02-14 |
| CN1429623A (zh) | 2003-07-16 |
| US7531501B1 (en) | 2009-05-12 |
| CA2265547C (en) | 2009-12-01 |
| US5922674A (en) | 1999-07-13 |
| US20080124401A1 (en) | 2008-05-29 |
| HK1022810A1 (en) | 2000-08-25 |
| US20020052309A1 (en) | 2002-05-02 |
| DE69731652T2 (de) | 2005-12-15 |
| CA2265547A1 (en) | 1998-03-19 |
| US20090285908A1 (en) | 2009-11-19 |
| EP0933995B1 (en) | 2004-11-17 |
| DE69731652D1 (de) | 2004-12-23 |
| EP0933995B8 (en) | 2005-01-19 |
| JP2009196999A (ja) | 2009-09-03 |
| ES2231889T3 (es) | 2005-05-16 |
| ATE282425T1 (de) | 2004-12-15 |
| US7803408B2 (en) | 2010-09-28 |
| CN1113669C (zh) | 2003-07-09 |
| JP2008133305A (ja) | 2008-06-12 |
| PT933995E (pt) | 2005-02-28 |
| WO1998010650A1 (en) | 1998-03-19 |
| CN1250281C (zh) | 2006-04-12 |
| EP0933995A1 (en) | 1999-08-11 |
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