JP2001502331A - 脳腫瘍に対するサイトカインで増強した免疫療法 - Google Patents

脳腫瘍に対するサイトカインで増強した免疫療法

Info

Publication number
JP2001502331A
JP2001502331A JP10518504A JP51850498A JP2001502331A JP 2001502331 A JP2001502331 A JP 2001502331A JP 10518504 A JP10518504 A JP 10518504A JP 51850498 A JP51850498 A JP 51850498A JP 2001502331 A JP2001502331 A JP 2001502331A
Authority
JP
Japan
Prior art keywords
cytokine
tumor
cells
formulation
days
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10518504A
Other languages
English (en)
Japanese (ja)
Inventor
ブレム,ヘンリー
エム. パードル,ドリュー
シー. トンプソン,レイド
エム. ジャフィー,エリザベス
ダブリュー. レオン,カム
ジー. エウェンド,マシュー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Publication of JP2001502331A publication Critical patent/JP2001502331A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0085Brain, e.g. brain implants; Spinal cord
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP10518504A 1996-10-16 1997-10-15 脳腫瘍に対するサイトカインで増強した免疫療法 Pending JP2001502331A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73159796A 1996-10-16 1996-10-16
US08/731,597 1996-10-16
PCT/US1997/018455 WO1998016246A1 (fr) 1996-10-16 1997-10-15 Immunotherapie amelioree par cytokine pour tumeurs cerebrales

Publications (1)

Publication Number Publication Date
JP2001502331A true JP2001502331A (ja) 2001-02-20

Family

ID=24940192

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10518504A Pending JP2001502331A (ja) 1996-10-16 1997-10-15 脳腫瘍に対するサイトカインで増強した免疫療法

Country Status (5)

Country Link
EP (1) EP0930892A1 (fr)
JP (1) JP2001502331A (fr)
AU (1) AU4818297A (fr)
CA (1) CA2267977A1 (fr)
WO (1) WO1998016246A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09506866A (ja) * 1993-12-14 1997-07-08 ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン 医薬として活性のある物質の免疫療法のための放出制御
US6277368B1 (en) 1996-07-25 2001-08-21 The Regents Of The University Of California Cancer immunotherapy using autologous tumor cells combined with cells expressing a membrane cytokine
DE69939821D1 (de) * 1998-04-02 2008-12-11 Univ California Zusammensetzungen zur erhöhung der zahl antigen präsentierender zellen und der antitumoralen antwort in menschlichen patienten
AU2457701A (en) * 1999-12-28 2001-07-09 Brown University Research Foundation Methods and products for tumor immunotherapy using cytokines
RU2272644C2 (ru) * 2000-06-29 2006-03-27 Мерк Патент Гмбх Усиление иммунной реакции, медиатором которой является слитый протеин антитело-цитокин, при помощи комбинированного лечения агентами, увеличивающими поглощение иммуноцитокина
US6911204B2 (en) 2000-08-11 2005-06-28 Favrille, Inc. Method and composition for altering a B cell mediated pathology
CA2479528A1 (fr) * 2002-03-25 2003-10-02 Technologies Biolactis Inc. Agents chimiotherapeutiqes utilises en tant qu'adjuvants vaccinaux contre le cancer et procedes therapeutiques correspondants
EP1374893A1 (fr) 2002-06-17 2004-01-02 NovImmune S.A. Vaccination au moyen de cellules immuno-isolées produisant un immunomodulateur
US7695723B2 (en) * 2002-12-31 2010-04-13 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
WO2017064571A1 (fr) 2015-09-25 2017-04-20 Maxivax Sa Vaccination avec des cellules immuno-isolées produisant un immunomodulateur
US20220403001A1 (en) 2018-06-12 2022-12-22 Obsidian Therapeutics, Inc. Pde5 derived regulatory constructs and methods of use in immunotherapy
WO2020123716A1 (fr) 2018-12-11 2020-06-18 Obsidian Therapeutics, Inc. Il12 liée à la membrane, compositions et procédés de régulation accordable
EP3935159A1 (fr) 2019-03-08 2022-01-12 Obsidian Therapeutics, Inc. Compositions d'anhydrase carbonique humaine 2 et procédés de régulation accordable
US20220267398A1 (en) 2019-06-12 2022-08-25 Obsidian Therapeutics, Inc. Ca2 compositions and methods for tunable regulation
US20220259284A1 (en) 2019-06-12 2022-08-18 Obsidian Therapeutics, Inc. Ca2 compositions and methods for tunable regulation
WO2021040736A1 (fr) 2019-08-30 2021-03-04 Obsidian Therapeutics, Inc. Compositions à base de car cd19 tandem et méthodes d'immunothérapie
US20220332780A1 (en) 2019-09-10 2022-10-20 Obsidian Therapeutics, Inc. Ca2-il15 fusion proteins for tunable regulation

Also Published As

Publication number Publication date
AU4818297A (en) 1998-05-11
CA2267977A1 (fr) 1998-04-23
EP0930892A1 (fr) 1999-07-28
WO1998016246A1 (fr) 1998-04-23

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