JP2001354526A - Hair restoration or hair tonic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a hair occurrence or hair tonic having excellent effects on hair growth, hair restoration promotion or hair nutrition and high safety. SOLUTION: This hair restoration or hair tonic comprises one or more kinds of crude medicines selected from Lepidium meyenii Walp and Uncaria tomentosa, crude medicines produced in Andes in South America or their active ingredient.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001] The present invention relates to the field of hair growth or hair growth agents.

[Background Art] In general, a hair restorer, a hair growth enhancer or a hair restorer is used continuously for a relatively long period of time, so that components used as a hair restorer, a hair restorer or a hair restorer are excellent in hair growth and promotion of hair growth. Alternatively, it is required to have a hair-growing effect and high safety.

[0003] Components conventionally used for this purpose include a vasodilator component (calpronum chloride), a male hormone (testosterone) inhibitory component (cash), a hair root energy component (pentadecanoic acid), and a scalp stimulating component (capsicum). In addition, there are corticosteroids and female hormones.

[0004] However, none of the various components conventionally used are satisfactory, having both effects.

[Problems to be Solved by the Invention] The present inventors have newly found crude drugs that can solve the above-mentioned problems.

[0006] The present invention relates to one or two kinds selected from crude drugs, maca and unyadegato produced in the Andes region of South America.
The present invention relates to pharmaceuticals, quasi-drugs, cosmetics, and miscellaneous goods containing seeds or their active ingredients.

[Embodiment of the Invention] Maca and unyadegato which are crude drugs according to the present invention will be described.

[0008] Maka is in the Andes in South America at an altitude of 4,000
Brassicaceae plants (scientific name,
The roots of Lepidium meyenii Walp have long been used by Indians for bread and cooking, and widely used as health foods. Its effects include enhancement of vitality, immunity, promotion of sperm formation, normalization of menstruation, reduction of symptoms before and after menopause, improvement of sex life, improvement of mental concentration and memory. However, no full-scale research on these human bodies has yet been found.

Unya de Gato (English name, Cat's Cl)
aw) is a vine-shaped tree that grows naturally in the upper part of the eastern jungle of the Andes in South America.
Indigenous Indians, who belong to the genus Ncaria tomentosa, have decocted their endothelium and used it to treat dysentery and tumors. In recent years, research by scientists from all over the world has shown an improvement in immune activity, an anti-inflammatory effect, etc., and it has been reported in Japan that it is effective for back pain and neuralgia.

[0010] In the present invention, the crude drug means one or two kinds of crude drug extracts of maca and unya degato, or a mixture of each crude drug extract.

The used part of the crude drug will be described. Maca is dried roots and used as an extraction material. Unyadegat is used to dry the endothelium and extract it.

The form of the crude drug can be freely adjusted as required, and can be cut or crushed into small pieces or small pieces. The crude drug extract can be used as it is or can be concentrated to a viscous liquid, and further dried and solidified.

[0013] The extract refers to a liquid leached by adding a suitable leaching agent to a crude drug or a liquid obtained by concentrating the leached liquid, and specifically, "extract", "tincture" and the like can be mentioned. Examples of the leaching agent include water, lower monohydric alcohols such as methanol and ethanol, ketones such as acetone, esters such as ethyl acetate, ethers such as diethyl ether, halogen alkanes such as chloroform, benzene and toluene. And aromatic hydrocarbons. These leaching agents may be used alone or in combination of two or more.

The hair growth or hair growth agent of the present invention can be administered orally or parenterally, but is preferably administered parenterally. As a preparation for parenteral administration,
External preparations are preferred, and specific examples of preparations include extracts, tinctures, alcoholic drinks, suspensions, plasters, ointments, haptics, liniments, lotions, aerosols, and the like. . These preparations can be provided as pharmaceuticals, quasi-drugs, cosmetics, and miscellaneous goods. Further, one or two types of crude drugs according to the present invention, or their active ingredients may be combined with cosmetics such as shampoos, rinses, conditioners, hair tonics, hair creams, and hair liquids.

The preparation can be carried out by a known preparation technique, and an appropriate preparation additive can be added to the preparation. Specific examples of the pharmaceutical additive include an excipient, a suspending agent, an emulsifier, a preservative, a humectant, and a fragrance.

The amount of the crude drug of the present invention or the active ingredient in the preparation may be appropriately determined in consideration of sex, age, symptoms, etc., and is 0.0001 to 30% by weight in terms of the crude drug. Is preferred. Further, 0.01 to 10% by weight is more preferable.

To the hair growth and growth agent of the present invention, those which are already known as components having a hair growth, hair growth promotion or hair growth effect may be added.

The hair growth or hair growth agent of the present invention is specifically used for hair growth, hair growth or hair growth. Therefore, the effects of hair growth or the hair restorer according to the present invention include hair growth, thinning hair, promotion of hair growth, promotion of hair growth, prevention of hair loss (hair loss), post-disease, postpartum hair loss, hair growth, hair growth failure, circular shape. Alopecia, seborrheic alopecia, diffuse alopecia, young baldness (mature alopecia), senile baldness and the like can be mentioned.

As a method of using the present invention, an appropriate amount may be applied, sprayed, or adhered to the site where hair is generated and its surroundings in accordance with the purpose of treatment or prevention.

Hereinafter, the present invention will be described in more detail with reference to Examples, but the present invention is not limited thereto.

Embodiment 1 A method for producing maca extract. Place 250 g of dried maca root powder in a 2 liter bottle, 5
Add 1500 ml of 0% ethanol and stopper tightly.
Let sit for a week. This is filtered, and the total amount is adjusted to 1500 ml by adding 50% ethanol.

Embodiment 2 FIG. A method for producing unya degato extract. 250 g of the dried shredded endothelium of Unya de Gato is placed in a 4 liter bottle, and 50% ethanol 2,000 m
(1), stopper tightly, and leave at room temperature for 2 weeks. This is filtered and 50% ethanol is added to bring the total volume to 2000 ml.

Embodiment 3 FIG. A method for producing a maca hair growth or hair restorer. 4,700 ml of 50% ethanol was added to 300 ml of the maca eluate of Example 1 to make the total amount 5,000 ml, and after stirring and filtering, a small amount of fragrance was added to give perfume.

Embodiment 4 FIG. A method for producing unya degato hair generation or hair restorer. Unyadegato extract 40 of Example 2
To 0 ml, 4,600 ml of 50% ethanol is added to make the total amount 5,000 ml, and after stirring and filtering, a small amount of fragrance is added to give flavor.

Embodiment 5 FIG. A method for producing a maca, unyadegato hair generation or hair restorer. 600 ml of maca extract of Example 1
Was added with 800 ml of the unya degato extract of Example 2, and 50% ethanol was further added to make the total amount 10,000.
After stirring and filtering, a small amount of fragrance is added to perfume.

Effects of the invention. A description will be given of examples of a maca hair growth or growth agent, unyadegato hair growth or growth agent, and clinical applications using the maca and unyadegato hair growth or growth agent.

Embodiment 6 FIG. Clinical application examples using maca hair development or hair restorer. When a 35-year-old man passed the age of 27, hair loss began to be noticeable during hair washing, the hair on the entire frontal region became thinner, and the hair on the left and right sides of the forehead became bald. Daily use of 1-2 ml of the maca hair development or hair restorer of Example 3 in the morning and evening
Twenty times, the entire frontal region was rubbed and massaged lightly.
From about one year later, looking at the thinned hair of the frontal hair,
0.5cm black hair was observed, and after 1 year and 6 months,
At the height of the forehead, 1-2 cm thin, but black hair appeared. Two years later, the amount of hair on the entire frontal region became considerably large, and black hair began to appear even on the bald hairline on the right and left sides of the forehead, and a clear hair growth effect was recognized.

Embodiment 7 FIG. Clinical Example using Unyadegato Hair Development or Hair Restorative. A 32-year-old woman, after finishing her third childbirth, suffers from physical weakness and mental fatigue, hair loss occurs on the entire head immediately after childbirth, and 1-2 months later,
Especially at the crown, the hair became thin enough to see the scalp. 1-2 ml of the unya degato hair-generating or hair-restoring agent of Example 4 was rubbed all over the head twice daily in the morning and evening to give a light massage. About 1-2 months later, 0.5-1c on the whole head
m black hair has grown. After 3-4 months, this 0.
Black hair of 5-1 cm grew, and after 6 months, the amount of hair also increased, and the state of thin hair on the crown was not recognized.

Embodiment 8 FIG. Clinical examples using maca, unya degato hair generation or hair restorer 1. 64-year-old man, gray hair starts to be noticeable from around 55 years old, hair from frontal region becomes thin from around 60 years old, and recently baldness on left and right forehead I'm up. Maca, unyadegato hair growth or hair restorer 1-2 of Example 5
ml was sprinkled on the scalp every morning and massaged lightly. No change was observed up to two months later, but the hair increased and the hair grew faster from about three months later. About 4-5 months later,
The hair on the forehead had black hair of 0.5 cm. Six months later, it was observed that the black hair that had grown had grown longer, and when the frontal white hair was divided, a large number of 0.5 cm black hair was growing.

Embodiment 9 FIG. Clinical application example using maca, unya degato hair generation or hair restorer 2.68-year-old man, hair quality was hard and gray hair, but recently hair loss was large and hair became like sleeping. 1-2 ml of the maca and unyadegato hair development or hair restorer of Example 5 was sprinkled evenly and twice daily in the morning and evening on the scalp and lightly massaged. Almost no change was felt until two months later, but less hair loss occurred after about three months, and after 4 to 5 months, the hair began to stand up, and the hair grew faster. Six months later, the proportion of black hair increased. During this time, there was no trouble due to the generation of the real hair or the use of the hair restorer.

Embodiment 10 FIG. Maca, Unyadegato Hair application or clinical application using hair restorer 3.63 year old male.
The hair was mixed with white hair as a whole, and the frontal part became thin, and the left and right sides of the forehead became bald. 1-2 ml of baldness on the left side was sprinkled twice daily in the morning and evening with a light massage using 1-2 ml of a maca and unya degato hair development or hair restorer. No change was observed until 2-3 months later, but 4-5
A month later, black hair of about 0.5 cm grew.
Six months later, the black hair that had grown on the left bald area grew as they grew. The right side maca, unyadegato hair development or the place where no hair restorer was sprinkled, was still bald.

The crude drugs (maca and unyadegato) according to the present invention have been used for a long time in the Andes region of South America, and have been used not only as foods but also for the treatment of various diseases, and are highly safe. Things. Further, no clinical problems were observed in the clinical test of the hair growth or hair growth agent of the present invention.

Claims (2)

[Claims] (1) Maca, Unya de Gato (English name, Cat's
Claw), a hair-generating or hair-growing agent containing one or two crude drugs or active ingredients thereof. 2. one selected from maca, unya de gato,
Or two kinds of crude drugs or pharmaceuticals, quasi-drugs, cosmetics, and miscellaneous goods containing those active ingredients.