JP2001342104A - Composition for vermin-controlling aerosol - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a composition for an easily applicable vermin-controlling aerosol having high vermin-controlling effect. SOLUTION: The composition for vermin-controlling aerosol is composed of an ester compound expressed by general formula (1) (R is methyl or methoxymethyl), a solvent having a boiling point of 30-210 deg.C and a propellant.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

[0001] The present invention relates to a composition for controlling aerosols.

[0002]

2. Description of the Related Art Various pest control aerosol formulations for controlling pests such as mosquitoes are known, but they are more effective in controlling pests and can be used easily. The development of aerosol preparations for medical use is always desired.

[0003]

Means for Solving the Problems The present inventors have made intensive studies under such circumstances and as a result, have found that a pesticidal aerosol composition comprising a specific pesticidal active ingredient, a specific solvent and a propellant, or the pesticidal composition. The present inventors have found that a composition for a pest control aerosol comprising an active ingredient and a propellant can exert an excellent control effect on pests, and have accomplished the present invention. That is, the present invention relates to the general formula (1) (Wherein, R represents a methyl group or a methoxymethyl group.) A composition for a pest control aerosol comprising an ester compound represented by the following formula (hereinafter referred to as the present compound), a solvent having a boiling point of 30 to 210 ° C, and a propellant. (Hereinafter referred to as the present composition 1), and a composition for a pest control aerosol comprising the present compound and a propellant (hereinafter referred to as the present composition 2).

[0004]

BEST MODE FOR CARRYING OUT THE INVENTION The present compound is disclosed in JP-A-12-633.
It is a compound described in JP-A No. 29, and can be produced according to the method described in the publication. The amount of the present compound in the present composition 1 is usually 0.0001 to 79.9991% by weight, and the amount of the present compound in the present composition 2 is generally 0.0001 to 80% by weight.

The propellant which can be used in the present composition 1 and the present composition 2 includes a liquid portion of the present composition 1 or the present composition 2 (for example, the present compound or the present compound and a compound having a boiling point of 30 to 30).
(Mixture of solvents at 210 ° C.), boiling point 2
Compounds having a temperature of 5 ° C. or lower, for example, dimethyl ether (boiling point −
24.8 ° C), propane (boiling point -42.1 ° C), n-butane (boiling point -0.5 ° C), isobutane (boiling point -12 ° C)
And the like, and these can be used alone or in a mixture of two or more. The amount of the propellant in the present composition 1 is usually 20 to 99.999% by weight,
The amount of the propellant in the present composition 2 is usually 20 to 99.9.
999% by weight.

The solvent which can be used in the present composition 1 is a solvent having a boiling point of 30 to 210 ° C. and a boiling point of 30 to 120 ° C.
C. is preferable, and a solvent having a boiling point of 30 to 100 C. is more preferable. Practically, the solvent has a boiling point of substantially 3
The present composition 1 containing only a solvent at 0 to 210 ° C is preferred.
Here, the solvent having a boiling point of 30 to 210 ° C means that the boiling points of all components constituting the solvent are substantially in the range of 30 to 210 ° C. Specifically, in the case of a single solvent, The boiling point of the solvent, and in the case of two or more mixed solvents, the boiling point of 95% by weight or more of the mixed solvent is 30 to 210%.
It is in the range of ° C. Boiling point 30-120 ° C
The same applies to the solvent having a boiling point of 30 to 100 ° C. Unless otherwise specified, the boiling point of the solvent means the boiling point at atmospheric pressure. Further, as the solvent,
A solvent that can keep the entire composition 1 uniform is preferable. Here, the term “the entire composition is uniform” means that it is in a so-called solution state, which does not substantially show a state of being separated between an aqueous layer and an oil layer, a state where crystals are precipitated, an emulsion state, a suspension state, and the like. Means

Examples of such a solvent include n-butyl alcohol (boiling point: 117.9 ° C.), sec.-butyl alcohol (boiling point: 99.5 ° C.), tert.-butyl alcohol (boiling point: 82.3 ° C.), n-butyl alcohol Propyl alcohol (boiling point 9
7.2 ° C.), isopropyl alcohol (boiling point 82.4)
° C), ethyl alcohol (boiling point 78.3 ° C), hexane (boiling point 69 ° C), heptane (boiling point 98.4 ° C), 2-methylpentane (boiling point 60 ° C), 2,2-dimethylbutane (boiling point 50 ° C) Octane (boiling point 125 ° C.), nonane (boiling point 149.5 ° C.), decane (boiling point 174 ° C.), undecane (boiling point 195.9 ° C.), IP1620 (trade name, manufactured by Idemitsu Petrochemical Co., Ltd., isoparaffin solvent, boiling point 1)
66-202 ° C), IP1016 (trade name, manufactured by Idemitsu Petrochemical Co., Ltd., isoparaffinic solvent, boiling point 73-140)
° C). In addition, water (boiling point 100
° C), but as described above, the composition 1
From the viewpoint of keeping the whole uniform, when water is used, it is compatible with water and compatible with the present compound and the propellant, and should be used as a mixed solvent with alcohols such as isopropanol. Is preferred.

[0008] The amount of the solvent in the present composition 1 is usually 0.00
09 to 79.9999% by weight, preferably 5 to 6%.
0% by weight. The composition 2 contains substantially no solvent.

The present composition 1 and the present composition 2 can appropriately contain other pest control active compounds, repellents, synergists, stabilizers and the like. This may be expected to further improve the efficacy or stabilize the efficacy for a long period of time. Other insecticidally active compounds include, for example, arethrin, tetramethrin, praethrin, phenothrin, resmethrin, cyphenothrin, permethrin, cypermethrin, deltamethrin, tralomethrin, cyfluthrin, framethrin, imiprotrin, etofenprox, fenvalerate, fenpropathrin, silaflufen , Transfluthrin, bifenthrin, empentrin, 2-methyl-4-oxo-3- (2-propynyl) -cyclopent-2-enyl 3- (2,2-dichlorovinyl) -2,2-dimethylcyclopropanecarboxylate Pyrethroid compounds, dichlorvos, fenitrothion, tetrachlorovinphos, phenthione, chlorpyrifos, diazonone, etc., organic phosphorus compounds, propoxer, carba Le, metoxadiazone, carbamate compounds such as Fenobucarb,
Lufenuron, chlorfluazuron, hexaflumuron, diflubenzuron, cyromazine, 1- (2,6-difluorobenzoyl) -3- [2-fluoro-4-
Chitin formation inhibitors such as (1,1,2,3,3,3-hexafluoropropoxy) phenyl] urea; juvenile hormone-like substances such as pyriproxyfen, methoprene, hydroprene, and phenoxycarb; neonicotinoids And N-phenylpyrazole compounds.

Examples of repellents include N, N-diethyl-m-toluamide, limonene, linalool, citronellal, menthol, menthon, hinokitiol, geraniol, eucalyptol, indoxacarb, carane-3,4-diol, MGK-R-326, MGK-
R-874, BAY-KBR-3023 and the like can be mentioned. As the synergist, for example, PBO, MGK2
64, S421, IBTA, Sinepirin 500 and the like.

As the stabilizer, for example, 2,6-di-t
And phenolic antioxidants such as -butyl-4-methylphenol.

An aerosol preparation comprising the present composition 1 or the present composition 2 can be obtained, for example, as follows. The aerosol container is filled with the present compound or the present compound and a solvent, and if necessary, other pest control active compounds, repellents, synergists, stabilizers and the like. This is achieved by mounting an aerosol valve on the container, filling the container with a propellant through a stem, shaking, and then mounting an actuator. As the actuator, for example, a button type, a trigger type, or the like can be used. When the aerosol preparation is a so-called full injection aerosol preparation in which all contents in the container are discharged by one injection, a full injection actuator is used instead of the actuator. You. The full-injection-type actuator has a mechanism in which once pressed, the pressed state is maintained.

The aerosol preparation comprising the present composition 1 or the present composition 2 is usually applied by spraying the insect body or habitat of the pest. The application rate depends on the type of pest to be controlled and the size of the place to be used.
0.001 to 10 of the present compound contained in the composition of the present invention.
In the aerosol preparation of the present invention that can be sprayed at 0 mg / sec, it is desirable to spray for about 0.1 to 100 seconds.
In addition, in the case of a full injection aerosol preparation, it is usually desirable to apply the preparation indoors.

Examples of the pests that can be controlled by the present composition 1 or the present composition 2 include the following. For example, sanitary pests include the house fly (Musca domestic)
a), flies such as housefly (Muscina stabulans),
Culex pipiens pallens, Culex pipiens pallens, Culex tritaeniorhynchus, and Culex pipiens pallens C
ulex quinquefasciatus, Aedes albopictus (Aedes alb)
opictus, Aedes aegypti and other mosquitoes; German cockroaches (Blattella germanica); black cockroaches (Periplaneta fuliginosa); (Che
yletus malaccensis) and the southern mites (Cheyletus moor)
ei) and other indoor mites, white lice (Pediculus humanus)
corporis). Wood pests include the termites (Reticulitermes speratus),
Examples include termites such as house termites (Coptotermes formosanus) and bark beetles. As an offending pest,
Midges, Drosophila, Ants, Bees and the like. Animal pests include cat flea (Ctenocephalides)
felis), dog flea (Ctenocephalides canis), human flea (Pulex irritans), and keops flea (Xenopsylla)
cheopis and other fleas, Haemaphysa
ticks such as lis longicornis, Ixodes ovatus and Boophilus microplus; lice such as bovine lice (Haematopinus eurysternus). Examples of the agricultural pests include aphids such as peach aphid (Myzus persicae), stink bugs such as a blue stink bug (Nezara antennata), planthoppers such as a brown planthopper (Laodelphax striatellus), and whiteflies such as silver leaf whitefly (Bemisia argentifolii). And the like.

[0015]

EXAMPLES Hereinafter, the present invention will be described in more detail with reference to Examples, but the present invention is not limited thereto.

Formulation Example 1 (1R) -trans-2,2-dimethyl-3- (1-propenyl (Z / E = 8/1)) cyclopropanecarboxylic acid (2,3,5,6-tetrafluoro- 4-methoxymethylphenyl) methyl (hereinafter referred to as compound A) 0.0
25 g was put in an aerosol can, and an aerosol valve was attached to the aerosol can. Then, 99.975 g of dimethyl ether was charged, shaken, and an actuator was attached to obtain an aerosol preparation 1.

Formulation Example 2 An aerosol preparation 2 was obtained in the same manner as in Preparation Example 1, except that the amount of compound A was 0.05 g and the amount of dimethyl ether was 99.95 g.

Formulation Example 3 An aerosol preparation 3 was obtained in the same manner as in Preparation Example 1, except that the amount of compound A was 0.1 g and the amount of dimethyl ether was 99.9 g.

Formulation Example 4 An aerosol formulation 4 was obtained in the same manner as in Formulation Example 1, except that the amount of Compound A was changed to 0.2 g and the amount of dimethyl ether was changed to 99.8 g.

Formulation Example 5 An aerosol preparation 5 is obtained by performing the same operation as in Preparation Example 1 except that the amount of compound A is 0.5 g and the amount of dimethyl ether is 99.5 g.

Formulation Example 6 The amount of compound A is 1 g, and the amount of dimethyl ether is 99
An aerosol preparation 6 is obtained by performing the same operation as in Preparation Example 1 except that the amount is changed to g.

Formulation Example 7 The amount of compound A was 5 g, and the amount of dimethyl ether was 95
An aerosol preparation 7 is obtained by performing the same operation as in Preparation Example 1 except that the amount is changed to g.

Formulation Example 8 0.025 g of the compound A and 49.975 g of a mixed solvent of water / isopropanol (1/1 (wt / wt)) are put in an aerosol can, an aerosol valve is attached, and 50 g of dimethyl ether is filled. Addition of a cap, and mounting of an actuator gave an aerosol formulation 8.

Formulation Example 9 The amount of compound A is 0.05 g, and the amount of water / isopropanol mixed solvent (1/1 (wt / wt)) is 49.95 g.
Aerosol preparation 9 was obtained by performing the same operation as in Preparation example 8 except that the above was used.

Formulation Example 10 The same operation as in Formulation Example 8 is carried out except that the amount of compound A is 0.1 g and the amount of water / isopropanol mixed solvent (1/1 (wt / wt)) is 49.9 g. Thereby, the aerosol preparation 10 was obtained.

Formulation Example 11 The same operation as in Formulation Example 8 is carried out except that the amount of compound A is 0.2 g and the amount of water / isopropanol mixed solvent (1/1 (wt / wt)) is 49.8 g. Thereby, the aerosol preparation 11 was obtained.

Formulation Examples 12-15 Water / isopropanol mixed solvent (1/1 (wt / w)
t)) instead of IP1620 (trade name, manufactured by Idemitsu Petrochemical Co., Ltd., isoparaffinic solvent, boiling point 166 to 202)
C)) to obtain Aerosol preparations 12 to 15 by performing the same operation as in Preparation examples 8 to 11.

Formulation Example 16 The amount of Compound A was 0.5 g, and IP1620 (trade name, manufactured by Idemitsu Petrochemical Co., Ltd., isoparaffin-based) was used instead of 49.975 g of a water / isopropanol mixed solvent (1/1 (wt / wt)). Solvent, boiling point 166-202 ° C) 49.5 g
An aerosol formulation 16 is obtained by performing the same operation as in Formulation Example 8 except that

Formulation Example 17 The amount of Compound A was 1 g, and IP1620 (trade name, manufactured by Idemitsu Petrochemical Co., Ltd., isoparaffinic solvent, boiling point 166)
Aerosol formulation 17 is obtained by performing the same operation as in Formulation Example 16 except that the amount is set to 49 g.

Formulation Example 18 The amount of Compound A was adjusted to 5 g, and IP1620 (trade name, manufactured by Idemitsu Petrochemical Co., Ltd., isoparaffinic solvent, boiling point 166)
The aerosol preparation 18 is obtained by performing the same operation as in Preparation Example 16 except that the amount of the mixture is adjusted to 45 g.

Formulation Examples 19 to 25 IP 1620 (trade name, manufactured by Idemitsu Petrochemical Co., Ltd., isoparaffinic solvent, boiling point: 166 to 202 ° C.)
Aerosol preparations 19 to 25 are obtained by performing the same operations as in Preparation examples 12 to 18 except that 1016 (trade name, manufactured by Idemitsu Petrochemical Co., Ltd., isoparaffin-based solvent, boiling point: 73 to 140 ° C.) is used.

Formulation Examples 26 to 32 The same operations as in Formulation Examples 12 to 18 are performed except that ethyl alcohol is used instead of IP1620 (trade name, manufactured by Idemitsu Petrochemical Co., Ltd., isoparaffinic solvent, boiling point: 166 to 202 ° C.). To obtain aerosol preparations 26 to 32.

Formulation Examples 33 to 39 By performing the same operation as in Formulation Examples 12 to 18 except that hexane is used instead of IP1620 (trade name, manufactured by Idemitsu Petrochemical Co., Ltd., isoparaffin solvent, boiling point: 166 to 202 ° C.). Aerosol preparations 33-39 are obtained.

Formulation Examples 40 to 78 Aerosol formulations 39 to 78 are obtained by performing the same operations as in Formulation Examples 1 to 39 except that a total release actuator is used instead of the actuator.

Formulation Examples 79 to 156 (1R) -trans-2,2-dimethyl-3- (1-propenyl (Z / E = 8/1)) cyclopropanecarboxylic acid (2,3 5,6-tetrafluoro-4-methylphenyl) methyl (hereinafter referred to as compound B)
Aerosol preparations 79 to 156 are obtained by performing the same operations as in Preparation examples 1 to 78, except for using.

Comparative Preparation Example 1 0.2 g of compound A and 49.8 g of neothiozole (Chuo Kasei Co., Ltd., boiling point: 200 to 280 ° C.) were placed in an aerosol can, and after mounting an aerosol valve, 25 g of dimethyl ether and 25 g of LPG were charged. Then, the mixture was shaken, and an actuator was attached thereto, thereby obtaining Comparative Aerosol Formulation 1.

Test Example 1 Approximately 50 adult Culex pipiens pallens females were released into a cubic test chamber (5.8 m ³ ) of 1.8 m on a side on which imitation paper was laid on the floor, and aerosol preparation 4 (composition) Compound A (0.2% by weight in the material) was sprayed once through a small window provided on each of the four side surfaces of the chamber such that the total spray amount was about 0.65 g, for a total of four times. After spraying, 2, 3, 5, 7, 10 and 15 minutes later, the number of Culex pipiens knocked down was counted, and KT50 (the time required for 50% of the test insects to be knocked down) was determined from the obtained data. Was. Further, the same test was carried out for Comparative Aerosol Formulation 1 (containing 0.2% by weight of Compound A in the composition). Table 1 shows the results.

[0038]

[Table 1]

Test Example 2 The same test as in Test Example 1 was conducted except that Aerosol Formulation 1 (containing 0.025% by weight of Compound A in the composition) was used instead of Aerosol Formulation 4. The results are shown in Table 2.

[0040]

[Table 2]

As shown in Tables 1 and 2, the aerosol preparation according to the present invention is different from the comparative aerosol preparation,
It can be seen that the aerosol preparation according to the present invention has a higher knock-down effect and even at a concentration as low as about 1/8 of the comparative aerosol preparation, exerts the same or higher efficacy as the comparative aerosol preparation.

Test Example 2 By conducting tests in the same manner as in Test Example 1 except that Compound B was used instead of Compound A, excellent pest control effect can be confirmed.

[0043]

According to the present invention, a pest control aerosol composition having a high pest control effect can be provided.

Claims (5)

[Claims] 1. The general formula (1) (Wherein, R represents a methyl group or a methoxymethyl group), having an boiling point of 30 to 210.
A composition for a pest control aerosol comprising a solvent at a temperature of ° C and a propellant. 2. The pest controlling aerosol composition according to claim 1, wherein the solvent has a boiling point of 30 to 120 ° C. 3. The pest controlling aerosol composition according to claim 1, wherein the solvent has a boiling point of 30 to 100 ° C. 4. The composition for controlling insect pests according to claim 3, wherein the solvent contains an alcohol. 5. The general formula (1) (In the formula, R represents a methyl group or a methoxymethyl group.) A pest controlling aerosol composition comprising an ester compound represented by the formula: and a propellant.