JP2001269348A - Spray nozzle of organism adhesive - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an organism adhesive spray nozzle that has a smaller gas delivery cross section, allows sufficient and homogeneous mixing atomization of two medicines to an optimal range, and is especially suitable for endoscope surgery, in a nozzle of a tool for spraying and applying the organism adhesive using mixture of two components by aseptic gas. SOLUTION: This spray nozzle comprises a pipe-like first nozzle as a first chemical passage, a pipe-like gas supply nozzle as a gas passage provided for the outer periphery of a circle concentric with the first nozzle, and a pipe-like second nozzle as a second chemical passage in parallel with and spaced from the gas supply nozzle. A delivery outlet of the first nozzle is projected than the spray outlet of the gas supply nozzle and provided on the straightly extension. A delivery outlet of the second nozzle is larger than the tip of the gas supply nozzle, and is formed in a bent shape so as to open to the extension line of the gas spray outlet of the gas supply nozzle.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a nozzle of a device for applying a bioadhesive which uses a mixture of two components, and more particularly, a two component mixture bioadhesion for hemostasis or suturing to an incised tissue or the like. The present invention relates to a nozzle of a spray device which is atomized and mixed and sprayed using an injection of a gas, particularly suitable for an endoscopic operation.

[0002]

2. Description of the Related Art Today, bioadhesives such as a mixture of two components, for example, a fibrinogen-containing solution and a thrombin-containing solution, are widely used for hemostasis of a diseased part such as an incised tissue, a substitute for suturing, or a suture assisting purpose. Coating devices for this application are also widely known. For example, JP
-25843, JP-A-64-40040, JP-A-11-104
76245 and the like. Basically, a syringe containing each of the liquid A and the liquid B is provided, and the plungers of the respective syringes are integrated so that two chemicals can be simultaneously discharged, and an appropriate length is provided at the tip of each syringe. The passages (nozzles) for the chemicals are arranged in parallel or concentrically, and the chemicals are discharged from the respective ends of the passages (nozzles) and mixed and applied at the ends.

[0003] As a means for more uniformly and efficiently mixing and applying, a spray-type instrument for atomizing and mixing and spraying two chemical solutions by utilizing the injection of sterile gas to a discharge portion of the chemical solution is also widely known. I have. For example, 3-4760
9, JP-A-5-57009, JP-A-6-205831,
There are JP-A-6-238001, JP-A-7-255729, JP-A-9-154848, actual climbing 2596623, etc.
Basically, these are configured such that various gas supply passages are provided in the device of the preceding configuration, opened at the chemical liquid discharge section at the tip, and aseptic gas is injected, and the chemical liquid is atomized and mixed and sprayed.

[0004]

Various proposals have been made for the nozzle portion of these spray-type instruments, including those having the structure disclosed in the above-mentioned publication. On the other hand, when using this device in endoscopic surgery, there are some clinically special requirements for this nozzle, one of which is the gas pressure inside the body cavity such as the abdominal cavity during endoscopic surgery. May not be increased more than necessary. This suggests that it is necessary to minimize the amount of sterile gas released when spraying the adhesive with a spray device, but on the other hand,
If the amount of release is suppressed, there is a conflicting problem that sufficient atomization and diffusion of the adhesive having viscosity cannot be obtained, and a nozzle structure that solves both conflicting problems is required. In other words, an ideal nozzle in this regard is a nozzle having a gas ejection port having a small ejection area (cross-sectional area) and having a shape capable of discharging to a certain extent.
Also, as another requirement, it is necessary to make the range of the tissue to be spray-applied moderate, and as a matter of course, it is necessary to ensure that the spray is applied to the entire area where the application is necessary, and that the unnecessary area is not sprayed as much as possible. Consideration is required.

[0005] Considering a conventional spray type nozzle, many chemical liquid supply nozzles have two passages arranged in parallel from a syringe containing a chemical liquid to a discharge port, and a discharge part at the tip is also provided. They are arranged in parallel and ejected separately. The reason for this is that when the two components of the adhesive are mixed, they harden in a short time when mixed, so that they are mixed outside of the appliance. This is because, in Japanese Patent Application Laid-Open No. 6-205831 in which the hood is provided, once the use is interrupted, the adhesive may harden at the tip end and may become unusable. On the other hand, gas outlets of gas supply nozzles are roughly classified into two types. One type is provided with one or two having a circular cross section corresponding to a chemical solution discharge port (Japanese Patent Application Laid-Open No. Hei 5 The other is on the outer side concentric with each of the chemical supply nozzles (Japanese Patent Application Laid-Open No. 9-154848, etc.) or on the outer periphery where two chemical supply nozzles are integrated (Japanese Patent Application Laid-Open No. 7-25572).
9) There is a doughnut-shaped cross section. In light of the requirements of the preceding stage, these nozzles, in order to reduce the injection amount of sterile gas, from the small cross-sectional area, as ideal in the above study, from a small cross-sectional area, high pressure, and a shape that can obtain a certain diffusion range The doughnut-shaped cross section is better than a circular shape having a larger relative cross-sectional area, and a single spout is naturally better. However, if the cross section is made into a donut shape without increasing the number of parts or complicating the structure, two gas outlets must be provided corresponding to the chemical solution supply port for uniform mixing and spraying of the chemical solution. One gas supply port
However, as in JP-A-7-255729,
If the two gas supply ports are surrounded by the gas supply ports, there is a problem that the cross-sectional area of gas ejection increases as a result. On the other hand, if the gas ejection port is made independent from the chemical liquid ejection port and becomes one, there is a problem that there is a concern that the two chemical liquids ejected from the two chemical liquid ejection ports are evenly mixed with each other.
The conventional one does not sufficiently satisfy the above requirements. Furthermore, in any of the conventional methods, since the discharge ports of the two chemicals are separately arranged in parallel, the application range of the sprayed adhesive is wide, and it can be imagined that the adhesive is diffused in an oval or cocoon shape. Depending on the application range, it may be unnecessarily wide and extend to the area that does not need to be applied. Further, although the chemical solution is atomized and sprayed, the discharge ports for the two chemical solutions are arranged in parallel with a certain width. Since the two components are separate, there is no problem at the center of the application range, but there is also a problem that the uniformity of the chemical solution is inferior toward the both ends in the longitudinal width direction.

[0006] In view of the above problems, the present invention is particularly suitable for endoscopic surgery, and it is possible to reduce the gas discharge cross-sectional area to achieve a sufficient and uniform mixing and atomization of two drugs. An object of the present invention is to provide a bioadhesive spray nozzle capable of spraying a medicine to an optimum application range.

[0007]

Means for Solving the Problems In order to solve the above problems, a bioadhesive spray nozzle of the present invention includes a pipe-shaped first nozzle serving as a first chemical liquid passage, and an outer peripheral side of a concentric circle with the first nozzle. And a pipe-shaped gas supply nozzle serving as a gas passage, and a second gas supply nozzle provided in parallel with the gas supply nozzle with a gap.
And a pipe-shaped second nozzle serving as a chemical liquid passage of the second nozzle. A tip portion serving as a discharge port of the first nozzle projects from a tip of a gas supply nozzle and is provided on this linear extension. The portion was provided to be longer than the tip of the gas supply nozzle and had a curved shape so as to open toward the extension of the gas outlet of the gas supply nozzle.

[0008] Further, an outer cylinder pipe accommodating the three nozzles of the first nozzle, the second nozzle, and the gas supply nozzle, and a bush for fixing each nozzle at a nozzle tip portion are provided at the tip of the outer cylinder pipe. The entire nozzle was provided integrally.

[0009]

According to the bioadhesive of the present configuration, even though each of the discharge ports of the two components of the liquid medicine is at the tip of another nozzle, the discharge port of the second nozzle is located on an extension of the discharge port of the tip of the first nozzle. Are opened, the two chemicals are mixed at the discharge section, and the liquid is mixed as if discharged from the same discharge port, so that highly uniform mixing can be achieved. If one is provided on the outer circumference on the concentric circle of the nozzle cross-section, the desired two drug solutions can be mixed and sprayed. Therefore, the requirements particularly required for the above-mentioned endoscopic surgery, that is,
In order not to increase the gas pressure inside the body cavity such as the abdominal cavity more than necessary,
It is possible to provide a gas supply nozzle having ideal requirements such as a shape capable of discharging a small amount of gas from a small area (cross-sectional area) to a high pressure and to some extent. at the same time,
With these structures, the application range of the adhesive becomes circular, so that it is possible to avoid unnecessary and wide application over a wide range.

[0010] Further, an outer cylinder pipe accommodating three nozzles of a first nozzle, a second nozzle and a gas supply nozzle, and a bush for fixing each nozzle at a nozzle tip portion is provided at the tip of the outer cylinder pipe. By integrating the whole, it becomes a single pipe and is effective for insertion into a trocar when used in endoscopic surgery, gas leakage prevention during pneumoperitoneum surgery, and is also suitable for endoscopic surgery It can be.

[0011]

An embodiment of a bioadhesive spray nozzle according to the present invention will be described in detail with reference to the drawings.

FIG. 1 shows a main part of a bioadhesive spray nozzle of the present invention, and a first nozzle (hereinafter, A liquid supply nozzle) of a stainless steel pipe serving as a first chemical liquid (hereinafter, A liquid) passage.
A liquid supply nozzle 1 is provided by providing a gap as a passage for aseptic gas on the outer peripheral side having a concentric circle section with the liquid A supply nozzle 1.
Gas supply nozzle 3 of a stainless steel pipe having a double pipe structure, and a second nozzle of a stainless steel pipe serving as a second chemical liquid (hereinafter referred to as B liquid) passage provided in parallel with the gas supply nozzle 3 at an interval. (Hereinafter referred to as a B liquid supply nozzle) 2, and the A liquid discharge port 11 at the tip of the A liquid supply nozzle 1 is provided on a linear extension line so as to slightly project from the gas ejection port 31 at the tip of the gas supply nozzle 3. The liquid B discharge port 21 at the tip of the liquid B supply nozzle 2 is provided to be longer than the distal end of the gas outlet 3 and is bent so as to open toward the discharge surface on the extension of the gas supply nozzle 3 so as to have a main structure. And In this embodiment, the discharge port 11 of the A liquid supply nozzle 1 is connected to the B liquid supply nozzle 2.
Although the discharge port 21 is shorter than the discharge port 21, the discharge port 11 side of the A liquid supply nozzle 1 may be longer.

FIGS. 2 and 3 are side sectional views, front views and AA of a nozzle showing an embodiment of the present invention including the main part of FIG.
In the cross-sectional view, the structure of the main part is the same as that of the previous stage except for the length of the gas supply nozzle 3, and in consideration of application in endoscopic surgery,
An outer pipe 4 made of a stainless steel pipe accommodating the A liquid supply nozzle 1, the B liquid supply nozzle 2, and the gas supply nozzle 3, and each of the nozzles bonded and attached to the inner surface at the tip of the outer pipe 4. A resin bush 5 fixed and integrated at the distal end is provided such that the distal end of the A liquid supply nozzle 1 and the distal end of the B liquid supply nozzle 2 protrude from the bush 5. Also, needless to say, the bush 5 is provided with a hole for penetrating or accommodating each of the nozzles, and a through hole for passing the A liquid supply nozzle 1 is provided in the bush 5.
Are provided as a hole diameter at which a gap serving as the gas passage 32 is generated. In the present embodiment, the gap serving as the gas supply passage 32 is provided to be smaller than the gap between the inner diameter of the gas supply nozzle 3 and the outer diameter of the A liquid supply nozzle 1, and the cross-sectional area of the gas outlet is set smaller. .

The bioadhesive spraying device having a nozzle according to the present invention is not shown in particular because it is common to conventional devices.
The components are connected to the syringes containing the liquid medicines A and B, respectively. The plunger is integrated as a general structure for this kind of device, and is pressed to simultaneously discharge the two liquid medicines. The base of the gas supply nozzle 3 is separated from the A liquid supply nozzle 1 by a Y-tube and a valve, and is connected to a gas supply device through a filter. Further, the whole base is preferably integrated and compacted as an operation part in consideration of usability, but is not particularly specified.

The means for spraying the adhesive by the spray nozzle according to the present invention comprises a chemical A supplied from the base of the A liquid supply nozzle 1,
The chemical liquid B supplied from the B liquid supply nozzle 2 passes through the A liquid passage 12 and the B liquid passage 22 inside each nozzle, and is discharged and mixed from each of the tip A liquid discharge ports 11 and the B liquid discharge ports 21,
The sterile gas supplied from the base of the gas supply nozzle 3 is supplied to the gas supply nozzle 3 and a part of the inner surface of the through hole of the bush 5,
The A liquid and the B liquid which are ejected from the gas ejection port 31 through the gas passage 32 in the gap with the outer surface of the liquid supply nozzle 1
The liquid is mixed and atomized and sprayed.

[0016]

According to the present invention, it is possible to minimize the amount of release of sterile gas which is particularly suitable for endoscopic surgery by the above-described operation, and to spray and mix the adhesive uniformly within an appropriate range. Can provide a bioadhesive spray nozzle that can maintain the gas pressure in the abdominal cavity during endoscopic surgery, such as the abdominal cavity, and reduce the effects of applying adhesive to unnecessary parts. In addition, the burden and adverse effects on the patient can be reduced.

[Brief description of the drawings]

FIG. 1 is a schematic side and front view showing a main part of a nozzle according to an embodiment of the present invention.

FIG. 2 is a side sectional view and a front view showing a nozzle according to an embodiment of the present invention.

FIG. 3 is a sectional view taken along the line AA in FIG. 2;

[Explanation of symbols]

 1. A liquid supply nozzle 11. A liquid discharge port 12. A liquid passage 2. B liquid supply nozzle 21. B liquid discharge port 22. B liquid passage Gas supply nozzle 31. Gas outlet 32. Gas passages 4. Outer pipe 5. bush

Claims (2)

[Claims] 1. A nozzle for mixing two chemicals, atomizing and spraying with a gas, wherein a first nozzle in the form of a pipe serving as a first chemical liquid passage, and a gas provided on an outer peripheral side having a cross section concentric with the first nozzle. A pipe-shaped gas supply nozzle as a passage,
The gas supply nozzle and a pipe-shaped second nozzle provided in parallel with a gap and serving as a second chemical liquid passage,
The tip of the nozzle serving as a discharge port protrudes from the gas supply nozzle and is provided on this linear extension. The tip of the discharge port of the second nozzle is provided longer than the tip of the gas supply nozzle. A bioadhesive spray nozzle having a curved shape so as to open toward the extension of the bioadhesive. 2. An outer pipe for accommodating the three nozzles of the first nozzle, the second nozzle, and the gas supply nozzle,
2. The bioadhesive spray nozzle according to claim 1, wherein a bush for fixing each nozzle at a nozzle tip is provided and integrated.