JP2000516579A5 - - Google Patents

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Publication number
JP2000516579A5
JP2000516579A5 JP1998506409A JP50640998A JP2000516579A5 JP 2000516579 A5 JP2000516579 A5 JP 2000516579A5 JP 1998506409 A JP1998506409 A JP 1998506409A JP 50640998 A JP50640998 A JP 50640998A JP 2000516579 A5 JP2000516579 A5 JP 2000516579A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998506409A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000516579A (ja
JP4026854B2 (ja
Filing date
Publication date
Priority claimed from US08/683,890 external-priority patent/US5994500A/en
Application filed filed Critical
Publication of JP2000516579A publication Critical patent/JP2000516579A/ja
Publication of JP2000516579A5 publication Critical patent/JP2000516579A5/ja
Application granted granted Critical
Publication of JP4026854B2 publication Critical patent/JP4026854B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP50640998A 1996-07-19 1997-07-18 腸栄養性glp―2ペプチドのアンタゴニスト Expired - Fee Related JP4026854B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/683,890 US5994500A (en) 1996-07-19 1996-07-19 Antagonists of intestinotrophic GLP-2 peptides
US08/683,890 1996-07-19
PCT/CA1997/000521 WO1998003547A1 (en) 1996-07-19 1997-07-18 Antagonists of intestinotrophic glp-2 peptides

Publications (3)

Publication Number Publication Date
JP2000516579A JP2000516579A (ja) 2000-12-12
JP2000516579A5 true JP2000516579A5 (Direct) 2005-02-10
JP4026854B2 JP4026854B2 (ja) 2007-12-26

Family

ID=24745881

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50640998A Expired - Fee Related JP4026854B2 (ja) 1996-07-19 1997-07-18 腸栄養性glp―2ペプチドのアンタゴニスト

Country Status (9)

Country Link
US (3) US5994500A (Direct)
EP (1) EP0914341B1 (Direct)
JP (1) JP4026854B2 (Direct)
AT (1) ATE338771T1 (Direct)
AU (1) AU739263B2 (Direct)
CA (1) CA2260291C (Direct)
DE (1) DE69736634T2 (Direct)
ES (1) ES2277676T3 (Direct)
WO (1) WO1998003547A1 (Direct)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6184201B1 (en) 1995-04-14 2001-02-06 Nps Allelix Corp. Intestinotrophic glucagon-like peptide-2 analogs
US5834428A (en) * 1995-04-14 1998-11-10 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
EP2218734B1 (en) 1996-04-12 2013-06-05 1149336 Ontario Inc. Glucagon-like peptide-2 analogs
US20020025933A1 (en) * 1996-08-30 2002-02-28 Knudsen Liselotte Bjerre GLP-2 derivatives
CA2236519C (en) * 1997-05-02 2011-09-13 1149336 Ontario Inc. Methods of enhancing functioning of the large intestine
SE9802080D0 (sv) * 1998-06-11 1998-06-11 Hellstroem Pharmaceutical composition for the treatment of functional dyspepsia and/or irritable bowel syndrome and new use of substances therein
CZ295890B6 (cs) 1998-12-07 2005-11-16 Societe De Conseils De Recherches Et D'application Analogy GLP-1, mající kyselinu aminoizomáselnou pozici 8 a D-arginin na pozici 36, jejich použití a farmaceutické prostředky je obsahující
GB9930882D0 (en) 1999-12-30 2000-02-23 Nps Allelix Corp GLP-2 formulations
US20070135345A1 (en) * 2000-09-18 2007-06-14 Henriksen Dennis B Use of GLP-2 for the treatment or prevention, of bone-related disorders
US7371721B2 (en) * 2000-09-18 2008-05-13 Sanos Bioscience A/S Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes
US20080249016A1 (en) * 2000-09-18 2008-10-09 Sanos Bioscience A/S Use of GLP-2 in a combination treatment for bone-related disorders
JP5161412B2 (ja) 2000-09-18 2013-03-13 サノス・バイオサイエンス・アクティーゼルスカブ Glp−1及びglp−2ペプチドの使用方法
EP1360202B1 (en) * 2001-02-16 2008-05-21 ConjuChem Biotechnologies Inc. Long lasting glucagon-like peptide 2 (glp-2) for the treatment of gastrointestinal diseases and disorders
WO2004035624A2 (en) * 2002-10-14 2004-04-29 Novo Nordisk A/S Glucagon - like peptide - 2 variants
ATE502665T1 (de) 2003-02-04 2011-04-15 Novo Nordisk As Injektionsvorrichtung mit drehbarer dosiseinstellungsvorrichtung
EP1608680A2 (en) * 2003-03-24 2005-12-28 Novo Nordisk A/S Glp-2 derivatives
ATE549028T1 (de) * 2003-05-15 2012-03-15 Tufts College Stabile analoga von glp-1
EP1711523B1 (en) 2003-12-16 2012-10-10 Ipsen Pharma Analogues of glp-1
ES2397241T3 (es) 2004-01-21 2013-03-05 Novo Nordisk Health Care Ag Conjugación de péptidos mediante transglutaminasa
ES2427150T3 (es) 2004-11-01 2013-10-29 Nps Pharmaceuticals, Inc. Tratamiento de pacientes con el síndrome del intestino corto con colon en continuidad
CN102659938B (zh) * 2005-05-04 2016-01-20 西兰制药公司 胰高血糖素样肽-2(glp-2)类似物
US7498141B2 (en) 2005-12-01 2009-03-03 Nps Pharmaceuticals, Inc. Assay system for GLP-2 receptor ligands
BRPI0718566A2 (pt) 2006-11-08 2014-03-11 Zealand Pharma As Peptídeo, análogo do mesmo, composição farmacêutica, usos de um análogo de peptídeo, e de uma molécula de ácido nucléico, de um vetor de expressão, ou de uma célula hospedeira, molécula de ácido nucléico, vetor de expressão, célula hospedeira, métodos para produzir o análogo de peptídeo-2 tipo-glucagon (glp-2), e, kit terapêutico.
EP2314616A1 (en) * 2009-10-23 2011-04-27 Ferring B.V. Peptidic GLP-2 agonists
CN103429742A (zh) 2010-10-15 2013-12-04 康奈尔大学 用于治疗内分泌、胃肠或自体免疫性疾病的组合物和方法
CN102924589B (zh) * 2011-08-11 2016-08-24 中肽生化有限公司 胰高血糖素样肽-2(glp-2)的类似物及其制备方法和用途
DK2755675T3 (en) 2011-09-12 2018-08-06 Amunix Operating Inc Glucagon-like peptide-2 compositions and methods for their preparation and use
CN107496932A (zh) 2012-02-27 2017-12-22 阿穆尼克斯运营公司 Xten缀合组合物和制造其的方法
CN104540850B (zh) 2012-05-03 2018-05-18 西兰制药公司 胰高血糖素样肽2(glp-2)类似物
SG11201903938XA (en) 2016-12-09 2019-05-30 Zealand Pharma As Acylated glp-1/glp-2 dual agonists
DK3638291T3 (da) 2017-06-16 2021-10-18 Zealand Pharma As Dosisregimer til indgivelse af glucagon-lignende-peptid-2 (GLP-2)-analoger
WO2020020904A1 (en) 2018-07-23 2020-01-30 Zealand Pharma A/S Therapeutic uses of glp-2 agonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2961045B2 (ja) * 1993-02-24 1999-10-12 日清製粉株式会社 腸管粘膜増強促進剤
US5990077A (en) * 1995-04-14 1999-11-23 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
US5912229A (en) * 1996-03-01 1999-06-15 Novo Nordisk Als Use of a pharmaceutical composition comprising an appetite-suppressing peptide

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