JP2000516230A - Iib/iiia拮抗薬としての環状カルバメート類およびイソオキサゾリジン類 - Google Patents
Iib/iiia拮抗薬としての環状カルバメート類およびイソオキサゾリジン類Info
- Publication number
- JP2000516230A JP2000516230A JP10509820A JP50982098A JP2000516230A JP 2000516230 A JP2000516230 A JP 2000516230A JP 10509820 A JP10509820 A JP 10509820A JP 50982098 A JP50982098 A JP 50982098A JP 2000516230 A JP2000516230 A JP 2000516230A
- Authority
- JP
- Japan
- Prior art keywords
- acetyl
- cis
- alkyl
- amino
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
- C07D265/08—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D265/10—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2422596P | 1996-08-15 | 1996-08-15 | |
US60/024,225 | 1996-08-15 | ||
US70090696A | 1996-08-21 | 1996-08-21 | |
US08/700,906 | 1996-08-21 | ||
PCT/US1997/013761 WO1998006707A1 (fr) | 1996-08-15 | 1997-08-13 | Carbamates et isoxazolidines cycliques antagonistes de l'iib/iiia |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2000516230A true JP2000516230A (ja) | 2000-12-05 |
Family
ID=26698197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10509820A Pending JP2000516230A (ja) | 1996-08-15 | 1997-08-13 | Iib/iiia拮抗薬としての環状カルバメート類およびイソオキサゾリジン類 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0922039A1 (fr) |
JP (1) | JP2000516230A (fr) |
AU (1) | AU3970697A (fr) |
CA (1) | CA2263311A1 (fr) |
WO (1) | WO1998006707A1 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000000481A1 (fr) * | 1998-06-29 | 2000-01-06 | Du Pont Pharmaceuticals Company | Isoxazolidines et carbamates cycliques utilises comme antagonistes de iib/iiia |
TWI290136B (en) * | 2000-04-05 | 2007-11-21 | Daiichi Seiyaku Co | Ethylenediamine derivatives |
WO2010149684A1 (fr) * | 2009-06-24 | 2010-12-29 | Boehringer Ingelheim International Gmbh | Nouveaux composés, composition pharmaceutique et procédés correspondants |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ239846A (en) * | 1990-09-27 | 1994-11-25 | Merck & Co Inc | Sulphonamide derivatives and pharmaceutical compositions thereof |
DE4124942A1 (de) * | 1991-07-27 | 1993-01-28 | Thomae Gmbh Dr K | 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
TW223629B (fr) * | 1992-03-06 | 1994-05-11 | Hoffmann La Roche | |
ATE198748T1 (de) * | 1993-11-24 | 2001-02-15 | Du Pont Pharm Co | Isoxazoline und isoxazole derivate als fibrinogen rezeptor antagonisten |
JPH09505589A (ja) * | 1993-11-24 | 1997-06-03 | ザ・デュポン・メルク・ファーマシュウティカル・カンパニー | フィブリノーゲン受容体アンタゴニストとして有用なイソオキサゾリン化合物 |
IL118007A0 (en) * | 1995-05-24 | 1996-08-04 | Du Pont Merck Pharma | Isoxazoline compounds pharmaceutical compositions containing them and their use |
-
1997
- 1997-08-13 AU AU39706/97A patent/AU3970697A/en not_active Abandoned
- 1997-08-13 WO PCT/US1997/013761 patent/WO1998006707A1/fr not_active Application Discontinuation
- 1997-08-13 EP EP97937112A patent/EP0922039A1/fr not_active Withdrawn
- 1997-08-13 CA CA002263311A patent/CA2263311A1/fr not_active Abandoned
- 1997-08-13 JP JP10509820A patent/JP2000516230A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0922039A1 (fr) | 1999-06-16 |
CA2263311A1 (fr) | 1998-02-19 |
WO1998006707A1 (fr) | 1998-02-19 |
AU3970697A (en) | 1998-03-06 |
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