JP2000515546A - 新規ホウ素酸含有核酸類及び診断剤としてのそれらの使用 - Google Patents
新規ホウ素酸含有核酸類及び診断剤としてのそれらの使用Info
- Publication number
- JP2000515546A JP2000515546A JP10507945A JP50794598A JP2000515546A JP 2000515546 A JP2000515546 A JP 2000515546A JP 10507945 A JP10507945 A JP 10507945A JP 50794598 A JP50794598 A JP 50794598A JP 2000515546 A JP2000515546 A JP 2000515546A
- Authority
- JP
- Japan
- Prior art keywords
- group
- acid
- polynucleotide
- modified
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/692,429 US5831046A (en) | 1996-08-05 | 1996-08-05 | Boronic acid-contaning nucleic acid monomers |
| US08/692,429 | 1996-08-05 | ||
| PCT/US1997/012834 WO1998005672A1 (en) | 1996-08-05 | 1997-07-31 | Novel boronic acid-containing nucleic acids and their use as diagnostic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2000515546A true JP2000515546A (ja) | 2000-11-21 |
| JP2000515546A5 JP2000515546A5 (enExample) | 2005-09-08 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10507945A Pending JP2000515546A (ja) | 1996-08-05 | 1997-07-31 | 新規ホウ素酸含有核酸類及び診断剤としてのそれらの使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US5831046A (enExample) |
| EP (1) | EP0923591A4 (enExample) |
| JP (1) | JP2000515546A (enExample) |
| AU (1) | AU729907B2 (enExample) |
| CA (1) | CA2262618C (enExample) |
| WO (1) | WO1998005672A1 (enExample) |
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| US7041510B2 (en) * | 1996-04-25 | 2006-05-09 | Bioarray Solutions Ltd. | System and method for programmable illumination pattern generation |
| WO1997040385A1 (en) | 1996-04-25 | 1997-10-30 | Bioarray Solutions, Llc | Light-controlled electrokinetic assembly of particles near surfaces |
| US6630577B2 (en) | 1996-08-05 | 2003-10-07 | Prolinx, Inc. | 1,2-Phenylenediboronic acid reagents and complexes |
| US6051251A (en) * | 1997-11-20 | 2000-04-18 | Alza Corporation | Liposome loading method using a boronic acid compound |
| US6232103B1 (en) * | 1998-03-23 | 2001-05-15 | Invitrogen Corporation | Methods useful for nucleic acid sequencing using modified nucleotides comprising phenylboronic acid |
| US6013783A (en) * | 1999-03-19 | 2000-01-11 | Prolinx Incorporated | Boronic acid containing oligonucleotides and polynucleotides |
| US20010049438A1 (en) * | 1999-03-19 | 2001-12-06 | Dix Connie Kim | Purification of primer extension products |
| KR100541842B1 (ko) * | 1999-03-19 | 2006-01-16 | 프로링스, 인코포레이티드 | 붕산을 함유하는 시약과 올리고누클레오티드 |
| US6248884B1 (en) | 1999-06-03 | 2001-06-19 | The Perkin-Elmer Corporation | Extended rhodamine compounds useful as fluorescent labels |
| JP2001183368A (ja) * | 1999-12-27 | 2001-07-06 | Fuji Photo Film Co Ltd | 固相担体表面へのｄｎａ断片の固定方法及びｄｎａチップ |
| US7102024B1 (en) | 2000-08-01 | 2006-09-05 | Schwartz David A | Functional biopolymer modification reagents and uses thereof |
| US6686461B1 (en) * | 2000-03-22 | 2004-02-03 | Solulink Bioscience, Inc. | Triphosphate oligonucleotide modification reagents and uses thereof |
| US9709559B2 (en) | 2000-06-21 | 2017-07-18 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
| ATE319087T1 (de) | 2000-06-21 | 2006-03-15 | Bioarray Solutions Ltd | Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays |
| US20040039129A1 (en) * | 2000-08-16 | 2004-02-26 | Hall Dennis G. | Non-pressurized methods for the preparation of conjugrated solid supports for boronic acids |
| US6919382B2 (en) | 2000-08-31 | 2005-07-19 | The Governors Of The University Of Alberta | Preparation and uses of conjugated solid supports for boronic acids |
| US7666588B2 (en) * | 2001-03-02 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy |
| US20030027135A1 (en) * | 2001-03-02 | 2003-02-06 | Ecker David J. | Method for rapid detection and identification of bioagents |
| US7226739B2 (en) | 2001-03-02 | 2007-06-05 | Isis Pharmaceuticals, Inc | Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations |
| WO2004060278A2 (en) * | 2002-12-06 | 2004-07-22 | Isis Pharmaceuticals, Inc. | Methods for rapid identification of pathogens in humans and animals |
| US20040121311A1 (en) | 2002-12-06 | 2004-06-24 | Ecker David J. | Methods for rapid detection and identification of bioagents in livestock |
| KR20040082273A (ko) | 2001-05-21 | 2004-09-24 | 아클라라 바이오사이언시스 인코퍼레이티드 | 단백질 분석을 위한 방법 및 조성물 |
| US7262063B2 (en) | 2001-06-21 | 2007-08-28 | Bio Array Solutions, Ltd. | Directed assembly of functional heterostructures |
| US8073627B2 (en) * | 2001-06-26 | 2011-12-06 | Ibis Biosciences, Inc. | System for indentification of pathogens |
| US7217510B2 (en) | 2001-06-26 | 2007-05-15 | Isis Pharmaceuticals, Inc. | Methods for providing bacterial bioagent characterizing information |
| ES2661167T3 (es) | 2001-10-15 | 2018-03-27 | Bioarray Solutions Ltd. | Análisis multiplexado de loci polimórficos mediante consulta simultánea y detección mediada por enzimas |
| EP1448800A4 (en) | 2001-11-21 | 2007-05-16 | Applera Corp | DIGITAL ASSAY |
| US20050221318A1 (en) * | 2002-03-15 | 2005-10-06 | Gouliaev Alex H | Building block forming a c-c bond upon reaction |
| WO2004047007A1 (en) | 2002-11-15 | 2004-06-03 | Bioarray Solutions, Ltd. | Analysis, secure access to, and transmission of array images |
| WO2004065000A1 (en) * | 2003-01-21 | 2004-08-05 | Illumina Inc. | Chemical reaction monitor |
| US8046171B2 (en) | 2003-04-18 | 2011-10-25 | Ibis Biosciences, Inc. | Methods and apparatus for genetic evaluation |
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| US8158354B2 (en) * | 2003-05-13 | 2012-04-17 | Ibis Biosciences, Inc. | Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture |
| US7964343B2 (en) * | 2003-05-13 | 2011-06-21 | Ibis Biosciences, Inc. | Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture |
| US8288523B2 (en) | 2003-09-11 | 2012-10-16 | Ibis Biosciences, Inc. | Compositions for use in identification of bacteria |
| US20060240412A1 (en) * | 2003-09-11 | 2006-10-26 | Hall Thomas A | Compositions for use in identification of adenoviruses |
| US20080138808A1 (en) * | 2003-09-11 | 2008-06-12 | Hall Thomas A | Methods for identification of sepsis-causing bacteria |
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- 1997-07-31 JP JP10507945A patent/JP2000515546A/ja active Pending
- 1997-07-31 EP EP97935061A patent/EP0923591A4/en not_active Withdrawn
- 1997-07-31 AU AU38090/97A patent/AU729907B2/en not_active Ceased
- 1997-07-31 WO PCT/US1997/012834 patent/WO1998005672A1/en not_active Ceased
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| EP0923591A4 (en) | 2001-01-31 |
| AU729907B2 (en) | 2001-02-15 |
| EP0923591A1 (en) | 1999-06-23 |
| CA2262618A1 (en) | 1998-02-12 |
| US5876938A (en) | 1999-03-02 |
| US5831045A (en) | 1998-11-03 |
| AU3809097A (en) | 1998-02-25 |
| CA2262618C (en) | 2007-10-02 |
| US5831046A (en) | 1998-11-03 |
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