JP2000514779A5 - - Google Patents

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Publication number
JP2000514779A5
JP2000514779A5 JP1997519715A JP51971597A JP2000514779A5 JP 2000514779 A5 JP2000514779 A5 JP 2000514779A5 JP 1997519715 A JP1997519715 A JP 1997519715A JP 51971597 A JP51971597 A JP 51971597A JP 2000514779 A5 JP2000514779 A5 JP 2000514779A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP1997519715A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000514779A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1996/016761 external-priority patent/WO1997019068A1/en
Publication of JP2000514779A publication Critical patent/JP2000514779A/ja
Publication of JP2000514779A5 publication Critical patent/JP2000514779A5/ja
Abandoned legal-status Critical Current

Links

JP09519715A 1995-11-17 1996-10-18 マトリックスメタロプロティナーゼのスルホンアミド阻害剤 Abandoned JP2000514779A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US737295P 1995-11-17 1995-11-17
US60/007,372 1995-11-17
PCT/US1996/016761 WO1997019068A1 (en) 1995-11-17 1996-10-18 Sulfonamide inhibitors of matrix metalloproteinases

Publications (2)

Publication Number Publication Date
JP2000514779A JP2000514779A (ja) 2000-11-07
JP2000514779A5 true JP2000514779A5 (enExample) 2004-10-28

Family

ID=21725784

Family Applications (1)

Application Number Title Priority Date Filing Date
JP09519715A Abandoned JP2000514779A (ja) 1995-11-17 1996-10-18 マトリックスメタロプロティナーゼのスルホンアミド阻害剤

Country Status (20)

Country Link
US (3) US5977141A (enExample)
EP (1) EP0874836B1 (enExample)
JP (1) JP2000514779A (enExample)
AT (1) ATE225779T1 (enExample)
AU (1) AU727569B2 (enExample)
BG (1) BG63967B1 (enExample)
BR (1) BR9611487A (enExample)
CZ (1) CZ291659B6 (enExample)
DE (1) DE69624262T2 (enExample)
DK (1) DK0874836T3 (enExample)
ES (1) ES2184893T3 (enExample)
HU (1) HUP9902083A3 (enExample)
IL (1) IL123901A (enExample)
NO (1) NO310231B1 (enExample)
NZ (1) NZ321293A (enExample)
PL (1) PL326700A1 (enExample)
PT (1) PT874836E (enExample)
SK (1) SK282833B6 (enExample)
WO (1) WO1997019068A1 (enExample)
ZA (1) ZA969584B (enExample)

Families Citing this family (53)

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US6613804B2 (en) 1993-05-20 2003-09-02 Encysive Pharmaceuticals, Inc. Biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin
US6500948B1 (en) 1995-12-08 2002-12-31 Agouron Pharmaceuticals, Inc. Metalloproteinase inhibitors-compositions, uses preparation and intermediates thereof
NZ325559A (en) * 1995-12-08 2000-01-28 Agouron Pharmaceuticals Inc Ag Metalloproteinase inhibitors, pharmaceutical compoMetalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical usitions containing them and their pharmaceutical uses, and methods and intermediates useful for theises, and methods and intermediates useful for their preparation r preparation
US6747027B1 (en) * 1996-07-22 2004-06-08 Pharmacia Corporation Thiol sulfonamide metalloprotease inhibitors
US6624177B1 (en) 1996-09-04 2003-09-23 Warner-Lambert Company Matrix metalloproteinase inhibitors and their therapeutic uses
EP0929542A1 (en) 1996-09-04 1999-07-21 Warner-Lambert Company Compounds for and a method of inhibiting matrix metalloproteinases
AU735013B2 (en) * 1996-09-04 2001-06-28 Warner-Lambert Company Matrix metalloproteinase inhibitors and their therapeutic uses
US5929097A (en) * 1996-10-16 1999-07-27 American Cyanamid Company Preparation and use of ortho-sulfonamido aryl hydroxamic acids as matrix metalloproteinase and tace inhibitors
US5977408A (en) * 1996-10-16 1999-11-02 American Cyanamid Company Preparation and use of β-sulfonamido hydroxamic acids as matrix metalloproteinase and TACE inhibitors
US6228869B1 (en) 1996-10-16 2001-05-08 American Cyanamid Company Ortho-sulfonamido bicyclic hydroxamic acids as matrix metalloproteinase and TACE inhibitors
US5962481A (en) * 1996-10-16 1999-10-05 American Cyanamid Company Preparation and use of ortho-sulfonamido heteroaryl hydroxamic acids as matrix metalloproteinase and tace inhibitors
US6548524B2 (en) 1996-10-16 2003-04-15 American Cyanamid Company Preparation and use of ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and TACE inhibitors
US6174915B1 (en) 1997-03-25 2001-01-16 Agouron Pharmaceuticals, Inc. Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses
US6008243A (en) * 1996-10-24 1999-12-28 Agouron Pharmaceuticals, Inc. Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use
WO1998025597A2 (en) * 1996-12-09 1998-06-18 Warner-Lambert Company Method for treating and preventing heart failure and ventricular dilatation
EP1366765A1 (en) * 1996-12-17 2003-12-03 Warner-Lambert Company Llc Use of matrix metalloproteinase inhibitors for treating neurological disorders and promoting wound healing
DK0946166T3 (da) 1996-12-17 2004-05-03 Warner Lambert Co Anvendelse af matrixmetalloproteinaseinhibitorer til fremme af sårheling
US5985900A (en) * 1997-04-01 1999-11-16 Agouron Pharmaceuticals, Inc. Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses
HU227183B1 (en) 1997-04-28 2010-09-28 Encysive Pharmaceuticals Inc Sulfonamide derivatives and pharmaceutical compositions containing them for the treatment of endothelin-mediated disorders
DE19719621A1 (de) 1997-05-09 1998-11-12 Hoechst Ag Sulfonylaminocarbonsäuren
ES2165640T3 (es) 1997-05-09 2002-03-16 Hoechst Ag Acidos diaminocarboxilicos sustituidos.
US6410580B1 (en) 1998-02-04 2002-06-25 Novartis Ag Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases
EP1918278A1 (en) 1998-02-04 2008-05-07 Novartis AG Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases
WO2000015213A1 (en) * 1998-09-11 2000-03-23 Shionogi & Co., Ltd. Remedal or preventive agent for congestive heart failure
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6313123B1 (en) 1999-01-27 2001-11-06 American Cyanamid Company Acetylenic sulfonamide thiol tace inhibitors
US6762178B2 (en) 1999-01-27 2004-07-13 Wyeth Holdings Corporation Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6225311B1 (en) 1999-01-27 2001-05-01 American Cyanamid Company Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors
US6946473B2 (en) 1999-01-27 2005-09-20 Wyeth Holdings Corporation Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors
US6340691B1 (en) 1999-01-27 2002-01-22 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors
US6200996B1 (en) 1999-01-27 2001-03-13 American Cyanamid Company Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors
US6753337B2 (en) 1999-01-27 2004-06-22 Wyeth Holdings Corporation Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
US6277885B1 (en) 1999-01-27 2001-08-21 American Cyanamid Company Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6358980B1 (en) 1999-01-27 2002-03-19 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
US6326516B1 (en) 1999-01-27 2001-12-04 American Cyanamid Company Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors
US6465508B1 (en) 2000-02-25 2002-10-15 Wyeth Preparation and use of ortho-sulfonamido aryl hydroxamic acids as matrix metalloproteinase inhibitors
US20030105144A1 (en) 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition
BR0213736A (pt) 2001-11-01 2004-10-19 Wyeth Corp ácidos hidroxâmicos de sulfonamida de arila alênica como metaloproteinase matriz e inibidores de tace
WO2003053912A1 (en) * 2001-12-20 2003-07-03 Bristol-Myers Squibb Company α-(N-SULPHONAMIDO)ACETAMIDE DERIVATIVES AS β-AMYLOID INHIBITORS
US6864478B2 (en) * 2002-04-22 2005-03-08 Visx, Incorporation Beam position monitoring for laser eye surgery
US7199155B2 (en) 2002-12-23 2007-04-03 Wyeth Holdings Corporation Acetylenic aryl sulfonate hydroxamic acid TACE and matrix metalloproteinase inhibitors
CA2511521C (en) 2002-12-30 2012-02-07 Angiotech International Ag Drug delivery from rapid gelling polymer composition
US7537774B2 (en) * 2005-12-23 2009-05-26 Orion Therapeautics, Llc Therapeutic formulation
JPWO2007102392A1 (ja) * 2006-03-03 2009-07-23 塩野義製薬株式会社 Mmp−13選択的阻害剤
US20100099676A1 (en) * 2006-11-02 2010-04-22 Shionogi & Co., Ltd. Sulfonylurea derivative capable of selectively inhibiting mmp-13
US8084477B2 (en) 2007-10-31 2011-12-27 Bristol-Myers Squibb Company Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production
US8093276B2 (en) * 2007-10-31 2012-01-10 Bristol-Myers Squibb Company Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production
JP2011523633A (ja) * 2008-05-08 2011-08-18 ブリストル−マイヤーズ スクイブ カンパニー 2−アリールグリシンアミド誘導体
US8044077B2 (en) * 2009-03-19 2011-10-25 Bristol-Myers Squibb Company Alpha-(N-sulfonamido)acetamide compounds incorporating deuterium as inhibitors of beta amyloid peptide production
US20110071199A1 (en) * 2009-03-20 2011-03-24 Bristol-Myers Squibb Company Thiophenyl Sulfonamides for the Treatment of Alzheimer's Disease
US7977362B2 (en) * 2009-03-20 2011-07-12 Bristol-Myers Squibb Company Alpha-(N-benzenesulfonamido)cycloalkyl derivatives
US8252821B2 (en) * 2009-04-14 2012-08-28 Bristol-Myers Squibb Company Bioavailable capsule compositions of amorphous alpha-(N-sulfonamido)acetamide compound
TW201043269A (en) * 2009-04-14 2010-12-16 Bristol Myers Squibb Co Bioavailable compositions of amorphous alpha-(N-sulfonamido)acetamide compound

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
EP0100158A3 (en) * 1982-07-28 1985-03-27 The Upjohn Company (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
DE3330603A1 (de) * 1983-08-25 1985-03-21 Hoechst Ag, 6230 Frankfurt Neue 2-amino-alkenylsulfonylharnstoffe
GB8609630D0 (en) * 1986-04-19 1986-05-21 Pfizer Ltd Anti-arrhythmia agents
AU675689B2 (en) * 1992-12-01 1997-02-13 Merck & Co., Inc. Fibrinogen receptor antagonists
CA2110524A1 (en) * 1992-12-10 1994-06-11 Gerald Burr Grindey Antitumor compositions and methods of treatment
US5506242A (en) * 1993-01-06 1996-04-09 Ciba-Geigy Corporation Arylsufonamido-substituted hydroxamic acids
US5552419A (en) * 1993-01-06 1996-09-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
US5455258A (en) * 1993-01-06 1995-10-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
PL310889A1 (en) * 1993-03-29 1996-01-08 Zeneca Ltd Heterocyclic derivatives as inhibitors of thrombocytes aggregation
IT1266582B1 (it) * 1993-07-30 1997-01-09 Recordati Chem Pharm Derivati (di)azacicloesanici e diazacicloeptanici
PL179997B1 (pl) * 1994-01-20 2000-11-30 British Biotech Pharm Nowe pochodne kwasu hydroksamowego i kwasu karboksylowego PL PL PL PL PL PL
US5514716A (en) * 1994-02-25 1996-05-07 Sterling Winthrop, Inc. Hydroxamic acid and carboxylic acid derivatives, process for their preparation and use thereof
US5817822A (en) * 1994-06-24 1998-10-06 Novartis Corporation Certain alpha-azacycloalkyl substituted arylsulfonamido acetohydroxamic acids
US5919940A (en) * 1995-01-20 1999-07-06 British Biotech Pharmaceuticals Limited Metalloproteinase inhibitors
WO1998025597A2 (en) * 1996-12-09 1998-06-18 Warner-Lambert Company Method for treating and preventing heart failure and ventricular dilatation
DK0946166T3 (da) * 1996-12-17 2004-05-03 Warner Lambert Co Anvendelse af matrixmetalloproteinaseinhibitorer til fremme af sårheling

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