JP2000513331A - 鬱病の治療におけるパロキセチン - Google Patents
鬱病の治療におけるパロキセチンInfo
- Publication number
- JP2000513331A JP2000513331A JP09533147A JP53314797A JP2000513331A JP 2000513331 A JP2000513331 A JP 2000513331A JP 09533147 A JP09533147 A JP 09533147A JP 53314797 A JP53314797 A JP 53314797A JP 2000513331 A JP2000513331 A JP 2000513331A
- Authority
- JP
- Japan
- Prior art keywords
- paroxetine
- depression
- severe
- post
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.ヒトまたはヒト以外の動物における、以下の鬱病サブタイプ:青年期、双極 性、初老期、重症、軽症、中程度、再発性、難治性、重度単極性、気分変調、出 産後、二重鬱病、精神病後、ウイルス感染後、死別、第1期、第2期、トラウマ 性ストレス疾患後、およびアルコール、ニコチン、コカイン、ヘロイン、ベンゾ ジアゼピンなどの濫用物質の投与中止に伴う鬱病の治療および/または予防方法 であって、これを必要とするヒトまたはヒト以外の動物に、パロキセチンまたは その医薬上許容される塩の効果的な、非毒性量を投与することを含む方法。 2.パロキセチンをパロキセチン塩酸塩として用いる請求項1記載の方法。 3.パロキセチン塩酸塩をヘミ水和物として用いる請求項2記載の方法。 4.ヒトまたはヒト以外の動物における、以下の鬱病サブタイプ:青年期、双極 性、初老期、重症、軽症、中程度、再発性、難治性、重度単極性、気分変調、出 産後、二重鬱病、精神病後、ウイルス感染後、死別、第1期、第2期、トラウマ 性ストレス疾患後、およびアルコール、ニコチン、コカイン、ヘロイン、ベンゾ ジアゼピンなどの濫用物質の投与中止に伴う鬱病の治療および/または予防のた めの薬剤を製造するためのパロキセチンまたはその医薬上許容される塩の使用。 5.パロキセチンをパロキセチン塩酸塩として用いる請求項4記載の使用。 6.パロキセチン塩酸塩をヘミ水和物として用いる請求項5記載の使用。 7.パロキセチンまたはその医薬上許容される塩と医薬上許容される担体の混合 物である、以下の鬱病サブタイプ:青年期、双極性、初老期、重症、軽症、中程 度、再発性、難治性、重度単極性、気分変調、出産後、二重鬱病、精神病後、ウ イルス感染後、死別、第1期、第2期、トラウマ性ストレス疾患後、およびアル コール、ニコチン、コカイン、ヘロイン、ベンゾジアゼピンなどの濫用物質の投 与中止に伴う鬱病の治療および/または治療における使用のための医薬組成物。 8.パロキセチンをパロキセチン塩酸塩として用いる請求項7記載の組成物。 9.パロキセチン塩酸塩をヘミ水和物として用いる請求項7記載の組成物。 10.以下の鬱病サブタイプ:青年期、双極性、初老期、重症、軽症、中程度、 再発性、難治性、重度単極性、気分変調、出産後、二重鬱病、精神病後、ウイル ス感染後、死別、第1期、第2期、トラウマ性ストレス疾患後、およびアルコー ル、ニコチン、コカイン、ヘロイン、ベンゾジアゼピンなどの濫用物質の投与中 止に伴う鬱病の治療および/または予防における薬剤としての使用説明書を伴う パック形態にて提供される、パロキセチンまたはその医薬上許容される塩を医薬 上許容される担体との混合物として含む、単位投与形態の薬剤。 11.パロキセチンをパロキセチン塩酸塩として用いる請求項10記載の薬剤。 12.パロキセチン塩酸塩をヘミ水和物として用いる請求項10記載の薬剤。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9605828.4 | 1996-03-20 | ||
GBGB9605828.4A GB9605828D0 (en) | 1996-03-20 | 1996-03-20 | Treatment method |
PCT/EP1997/001353 WO1997034602A1 (en) | 1996-03-20 | 1997-03-17 | Paroxetine in treatment of depression |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2000513331A true JP2000513331A (ja) | 2000-10-10 |
Family
ID=10790697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP09533147A Ceased JP2000513331A (ja) | 1996-03-20 | 1997-03-17 | 鬱病の治療におけるパロキセチン |
Country Status (8)
Country | Link |
---|---|
US (1) | US6121291A (ja) |
EP (2) | EP1300144A3 (ja) |
JP (1) | JP2000513331A (ja) |
CY (1) | CY2482B1 (ja) |
DE (1) | DE69721756T2 (ja) |
ES (1) | ES2199357T3 (ja) |
GB (1) | GB9605828D0 (ja) |
WO (1) | WO1997034602A1 (ja) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2193939C (en) * | 1996-12-24 | 2002-02-12 | K.S. Keshava Murthy | Useful form of anhydrous paroxetine hydrochloride |
ES2329739T3 (es) | 1997-04-07 | 2009-11-30 | Georgetown University | Analogos de cocaina. |
GB9812941D0 (en) * | 1998-06-16 | 1998-08-12 | Smithkline Beecham Plc | Method of treatment |
ES2159260B1 (es) * | 1999-06-22 | 2002-05-01 | Smithkline Beechan Plc | Nueva composicion de metanosulfonato de paroxetina |
GB0003232D0 (en) * | 2000-02-11 | 2000-04-05 | Smithkline Beecham Plc | Novel composition |
AU2003237524A1 (en) * | 2002-07-08 | 2004-01-23 | University Of Florida | Use of ssri inhibitors to prevent or ameliorate trauma-related psychological disorders |
US20040220153A1 (en) * | 2002-09-24 | 2004-11-04 | Jost-Price Edward Roydon | Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines |
US20050266082A1 (en) * | 2004-05-26 | 2005-12-01 | Patel Satishkumar A | Preparation of stable paroxetine HC1 ER tablets using a melt granulation process |
WO2006023347A1 (en) * | 2004-08-20 | 2006-03-02 | Alpharma, Inc. | Paroxetine formulations |
CA2629514A1 (en) * | 2005-11-14 | 2007-05-24 | Auspex Pharmaceuticals, Inc. | Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties |
US9138430B2 (en) * | 2007-12-27 | 2015-09-22 | Mylan Specialty L.P. | Formulation and method for the release of paroxetine in the large intestine |
TWI646971B (zh) * | 2015-12-04 | 2019-01-11 | 鄭恩哲 | 阻斷海洛因或嗎啡毒品中毒路徑的點滴處方及其應用 |
US11730706B1 (en) * | 2022-07-07 | 2023-08-22 | Antecip Bioventures Ii Llc | Treatment of depression in certain patient populations |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
ES2058061T3 (es) * | 1985-10-25 | 1994-11-01 | Beecham Group Plc | Derivado de piperidina, su preparacion y su uso como medicamento. |
US5114976A (en) * | 1989-01-06 | 1992-05-19 | Norden Michael J | Method for treating certain psychiatric disorders and certain psychiatric symptoms |
GB9325644D0 (en) * | 1993-12-15 | 1994-02-16 | Smithkline Beecham Plc | Novel formulation |
-
1996
- 1996-03-20 GB GBGB9605828.4A patent/GB9605828D0/en active Pending
-
1997
- 1997-03-17 US US09/142,990 patent/US6121291A/en not_active Expired - Fee Related
- 1997-03-17 ES ES97915381T patent/ES2199357T3/es not_active Expired - Lifetime
- 1997-03-17 WO PCT/EP1997/001353 patent/WO1997034602A1/en active IP Right Grant
- 1997-03-17 EP EP02078890A patent/EP1300144A3/en not_active Withdrawn
- 1997-03-17 EP EP97915381A patent/EP0893997B1/en not_active Expired - Lifetime
- 1997-03-17 DE DE69721756T patent/DE69721756T2/de not_active Expired - Fee Related
- 1997-03-17 JP JP09533147A patent/JP2000513331A/ja not_active Ceased
-
2004
- 2004-11-05 CY CY0400079A patent/CY2482B1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP1300144A2 (en) | 2003-04-09 |
DE69721756T2 (de) | 2003-12-04 |
WO1997034602A1 (en) | 1997-09-25 |
ES2199357T3 (es) | 2004-02-16 |
EP0893997A1 (en) | 1999-02-03 |
US6121291A (en) | 2000-09-19 |
EP0893997B1 (en) | 2003-05-07 |
GB9605828D0 (en) | 1996-05-22 |
DE69721756D1 (de) | 2003-06-12 |
EP1300144A3 (en) | 2003-05-21 |
CY2482B1 (en) | 2005-06-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20070417 |
|
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