JP2000511425A5 - - Google Patents

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Publication number
JP2000511425A5
JP2000511425A5 JP1997543071A JP54307197A JP2000511425A5 JP 2000511425 A5 JP2000511425 A5 JP 2000511425A5 JP 1997543071 A JP1997543071 A JP 1997543071A JP 54307197 A JP54307197 A JP 54307197A JP 2000511425 A5 JP2000511425 A5 JP 2000511425A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP1997543071A
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English (en)
Japanese (ja)
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JP2000511425A (ja
JP4318752B2 (ja
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Publication date
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Priority claimed from PCT/US1997/009610 external-priority patent/WO1997045450A1/en
Publication of JP2000511425A publication Critical patent/JP2000511425A/ja
Publication of JP2000511425A5 publication Critical patent/JP2000511425A5/ja
Application granted granted Critical
Publication of JP4318752B2 publication Critical patent/JP4318752B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP54307197A 1996-05-31 1997-05-30 抗エンドグリンモノクローナル抗体および抗血管新生治療におけるその使用 Expired - Lifetime JP4318752B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65595396A 1996-05-31 1996-05-31
US08/655,953 1996-05-31
PCT/US1997/009610 WO1997045450A1 (en) 1996-05-31 1997-05-30 Anti-endoglin monoclonal antibodies and their use in antiangiogenic therapy

Publications (3)

Publication Number Publication Date
JP2000511425A JP2000511425A (ja) 2000-09-05
JP2000511425A5 true JP2000511425A5 (cg-RX-API-DMAC10.html) 2005-01-13
JP4318752B2 JP4318752B2 (ja) 2009-08-26

Family

ID=24631047

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54307197A Expired - Lifetime JP4318752B2 (ja) 1996-05-31 1997-05-30 抗エンドグリンモノクローナル抗体および抗血管新生治療におけるその使用

Country Status (8)

Country Link
US (2) US5928641A (cg-RX-API-DMAC10.html)
EP (1) EP0938505B1 (cg-RX-API-DMAC10.html)
JP (1) JP4318752B2 (cg-RX-API-DMAC10.html)
AT (1) ATE214075T1 (cg-RX-API-DMAC10.html)
CA (1) CA2256413C (cg-RX-API-DMAC10.html)
DE (1) DE69710911T2 (cg-RX-API-DMAC10.html)
ES (1) ES2169864T3 (cg-RX-API-DMAC10.html)
WO (1) WO1997045450A1 (cg-RX-API-DMAC10.html)

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US5965132A (en) 1992-03-05 1999-10-12 Board Of Regents, The University Of Texas System Methods and compositions for targeting the vasculature of solid tumors
US6749853B1 (en) 1992-03-05 2004-06-15 Board Of Regents, The University Of Texas System Combined methods and compositions for coagulation and tumor treatment
DE19845798A1 (de) * 1998-09-29 2000-04-13 Schering Ag Verwendung von Neoangiogenese-Markern für Diagnose und Therapie von Tumoren, diese enthaltende Mittel, sowie Verfahren zu deren Herstellung
AU770381B2 (en) * 1999-01-22 2004-02-19 Burnham Institute, The Homing pro-apoptotic conjugates and methods of using same
ES2311507T3 (es) * 2000-02-10 2009-02-16 MASSACHUSETTS EYE & EAR INFIRMARY Terapia fotodinamica para tratamiento de afecciones oftalmicas.
AU2006203034B2 (en) * 2000-02-10 2006-09-07 Massachusetts Eye And Ear Infirmary Methods and compositions for treating conditions of the eye
DE10043481A1 (de) * 2000-09-04 2002-04-11 Vectron Therapeutics Ag Imt Humaner Antikörper gegen Endoglin (CD105) und seine Verwendung
JP2003021631A (ja) * 2001-05-10 2003-01-24 Chugai Pharmaceut Co Ltd 骨転移抑制剤のスクリーニング方法
US20030129193A1 (en) * 2001-09-27 2003-07-10 Board Of Regents, The University Of Texas System And Peregrine Pharmaceuticals, Inc. Combined methods for tumor vasculature coaguligand treatment
AP2012006644A0 (en) * 2003-08-01 2012-12-31 Genentech Inc Anti-VEGF antibodies
WO2005044853A2 (en) * 2003-11-01 2005-05-19 Genentech, Inc. Anti-vegf antibodies
US7758859B2 (en) 2003-08-01 2010-07-20 Genentech, Inc. Anti-VEGF antibodies
US20050106667A1 (en) 2003-08-01 2005-05-19 Genentech, Inc Binding polypeptides with restricted diversity sequences
EP1533617A1 (en) * 2003-11-19 2005-05-25 RMF Dictagene S.A. Angiogenesis inhibiting molecules, their selection, production and their use in the treatment and diagnosis of cancer
US20060052286A1 (en) * 2004-08-13 2006-03-09 Yale University Factor VII conjugates for selectively treating neovascularization disorders
US7740849B2 (en) * 2004-09-24 2010-06-22 Beth Israel Deaconess Medical Center Use of compounds that bind soluble endoglin and SFLT-1 for the treatment of pregnancy related hypertensive disorders
JP5270161B2 (ja) 2004-09-24 2013-08-21 ベス イスラエル デアコネス メディカル センター 妊娠合併症を診断および処置する方法
EP1839057B1 (en) * 2004-12-15 2010-08-25 Beth Israel Deaconess Medical Center Nucleic acids and polypeptides useful for diagnosing and treating complications of pregnancy
US20090286271A1 (en) * 2006-05-31 2009-11-19 Karumanchi Ananth S Methods of Diagnosing and Treating Complications of Pregnancy
EP2087001B1 (en) 2006-11-02 2016-10-26 Acceleron Pharma, Inc. Alk1 receptor and ligand antagonists and uses thereof
US8642031B2 (en) 2006-11-02 2014-02-04 Acceleron Pharma, Inc. Antagonists of BMP9, BMP10, ALK1 and other ALK1 ligands, and uses thereof
US10059756B2 (en) 2006-11-02 2018-08-28 Acceleron Pharma Inc. Compositions comprising ALK1-ECD protein
TWI468417B (zh) 2007-11-30 2015-01-11 Genentech Inc 抗-vegf抗體
CA2723449C (en) 2008-05-02 2020-01-21 Acceleron Pharma Inc. Methods and compositions based on alk1 antagonists for modulating angiogenesis and pericyte coverage
US20100082438A1 (en) * 2008-10-01 2010-04-01 Ronnie Jack Garmon Methods and systems for customer performance scoring
US8221753B2 (en) 2009-09-30 2012-07-17 Tracon Pharmaceuticals, Inc. Endoglin antibodies
KR101553740B1 (ko) 2009-08-17 2015-09-17 트라콘 파마수티칼즈, 인코포레이티드 항엔도글린 항체 및 항vegf 제제를 사용한 암 치료를 위한 병용 요법
EP3144323A3 (en) * 2009-12-09 2017-05-31 Bayer Pharma Aktiengesellschaft Anti-c4.4a antibodies and uses thereof
CN103619352A (zh) * 2011-02-23 2014-03-05 健康研究公司 抗内皮因子抗体和表达新人/鼠嵌合内皮因子的敲入小鼠
US9255595B2 (en) * 2011-04-29 2016-02-09 Bae Systems Information And Electronic Systems Integration Inc. Optical dome bezel
UA115789C2 (uk) 2012-09-05 2017-12-26 Трейкон Фармасутікалз, Інк. Композиція антитіла до cd105 та її застосування
ES2710203T3 (es) 2013-06-14 2019-04-23 Agilent Technologies Inc Sistema y método para facilitar la clasificación manual de objetos
GB201402006D0 (en) 2014-02-06 2014-03-26 Oncomatryx Biopharma S L Antibody-drug conjugates and immunotoxins
WO2016077451A1 (en) 2014-11-12 2016-05-19 Tracon Pharmaceuticals, Inc. Anti-endoglin antibodies and uses thereof
US9926375B2 (en) 2014-11-12 2018-03-27 Tracon Pharmaceuticals, Inc. Anti-endoglin antibodies and uses thereof
RU2763916C2 (ru) 2015-09-23 2022-01-11 Дженентек, Инк. Оптимизированные варианты анти-vegf антител
RU2607029C1 (ru) * 2015-10-20 2017-01-10 ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ "РОССИЙСКИЙ НАУЧНЫЙ ЦЕНТР РАДИОЛОГИИ И ХИРУРГИЧЕСКИХ ТЕХНОЛОГИЙ" МИНИСТЕРСТВА ЗДРАВООХРАНЕНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ / ФГБУ "РНЦРХТ" Минздрава России ШТАММ ГИБРИДНЫХ КУЛЬТИВИРУЕМЫХ КЛЕТОК ЖИВОТНЫХ Mus musculus L. - EN-4C9 - ПРОДУЦЕНТ МОНОКЛОНАЛЬНЫХ АНТИТЕЛ ПРОТИВ ЭНДОГЛИНА (CD105) ЧЕЛОВЕКА
CN106928359B (zh) * 2015-12-30 2020-10-13 广西医科大学 一种CD105纳米抗体Nb59
CN106928355B (zh) * 2015-12-30 2020-09-29 广西医科大学 一种CD105纳米抗体Nb184
GB2566221B (en) 2016-06-24 2021-08-04 Univ South Carolina Inhibin as targetable regulators of angiogenesis
EP3900733A1 (en) 2020-04-24 2021-10-27 Derma Innovate S.L. Src kinase activators and eng function inhibitors as enhancers of skin homeostasis/regeneration and hair growth
CN116063496B (zh) * 2022-08-15 2023-10-24 营龄(武汉)生物科技有限公司 载药的人血白蛋白联合单克隆抗体在制备药物组合物中的用途
CN115991773B (zh) * 2022-08-15 2023-11-17 营龄(武汉)生物科技有限公司 一种含有人血白蛋白的药物组合物
WO2026017807A1 (en) 2024-07-18 2026-01-22 Beech Biotech Sa Compositions and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL94389A0 (en) * 1989-06-01 1991-03-10 Health Research Inc Monoclonal antibody reactive to a unique antigen widely present on various human leukemia and lymphoma cells and method of using same for diagnosis and treatment
US5660827A (en) * 1992-03-05 1997-08-26 Board Of Regents, The University Of Texas System Antibodies that bind to endoglin

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