JP2000511406A - レプチンアッセイ - Google Patents

レプチンアッセイ

Info

Publication number
JP2000511406A
JP2000511406A JP09538203A JP53820397A JP2000511406A JP 2000511406 A JP2000511406 A JP 2000511406A JP 09538203 A JP09538203 A JP 09538203A JP 53820397 A JP53820397 A JP 53820397A JP 2000511406 A JP2000511406 A JP 2000511406A
Authority
JP
Japan
Prior art keywords
leptin
promoter
nucleic acid
response element
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP09538203A
Other languages
English (en)
Japanese (ja)
Inventor
ローゼンブラム，チヤールズ・アイ
フアン・デル・プルウフ，レオナルドウス
クレシ，サジヤド・エイ
カリ，ドリス・エフ
ヘス，ジヨン・ダブリユ
トタ，マイケル・アール
チエン，フアン
Original Assignee
メルク エンド カンパニー インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9611785.8A external-priority patent/GB9611785D0/en
Application filed by メルク エンド カンパニー インコーポレーテッド filed Critical メルク エンド カンパニー インコーポレーテッド
Publication of JP2000511406A publication Critical patent/JP2000511406A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP09538203A 1996-04-22 1997-04-18 レプチンアッセイ Pending JP2000511406A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US1605196P 1996-04-22 1996-04-22
GBGB9611785.8A GB9611785D0 (en) 1996-06-06 1996-06-06 Leptin assay
US3100296P 1996-11-15 1996-11-15
US9611785.8 1996-11-15
US60/016,051 1996-11-15
US60/031,002 1996-11-15
PCT/US1997/006505 WO1997040380A1 (fr) 1996-04-22 1997-04-18 Dosage de la leptine

Publications (1)

Publication Number Publication Date
JP2000511406A true JP2000511406A (ja) 2000-09-05

Family

ID=27268306

Family Applications (1)

Application Number Title Priority Date Filing Date
JP09538203A Pending JP2000511406A (ja) 1996-04-22 1997-04-18 レプチンアッセイ

Country Status (4)

Country Link
EP (1) EP0914611A4 (fr)
JP (1) JP2000511406A (fr)
CA (1) CA2252443A1 (fr)
WO (1) WO1997040380A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6310034B1 (en) 1993-05-21 2001-10-30 Ut-Battelle, Llc Agouti polypeptide compositions
US6001968A (en) * 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
US7148004B1 (en) 1997-01-16 2006-12-12 The Rockefeller University Oligonucleotides of the OB-R isoforms and methods of diagnosing body weight
US7084252B1 (en) 1996-01-16 2006-08-01 The Rockefeller University DB, the receptor for leptin
US7063958B1 (en) 1996-01-16 2006-06-20 The Rockefeller University Nucleic acids db, the receptor for leptin
US7619079B2 (en) 1996-02-14 2009-11-17 The Rockefeller University Db, the receptor for leptin, nucleic acids encoding the receptor, and uses thereof
WO1998020158A1 (fr) * 1996-11-01 1998-05-14 Smithkline Beecham Plc Procede pour la detection de composes modulant les effets de la proteine de l'obesite (ob)
ATE278952T1 (de) * 1998-07-28 2004-10-15 Vlaams Interuniv Inst Biotech Leptin vermittelte geninduktion
IL132313A0 (en) 1999-10-11 2001-03-19 Yeda Res & Dev Leptin assay

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401629A (en) * 1990-08-07 1995-03-28 The Salk Institute Biotechnology/Industrial Associates, Inc. Assay methods and compositions useful for measuring the transduction of an intracellular signal
US5643748A (en) * 1994-09-14 1997-07-01 Progenitor, Inc. HU-B1.219, a novel human hematopoietin receptor
EP0832284A1 (fr) * 1995-05-30 1998-04-01 Smithkline Beecham Plc Procede de detection de composes modulant les effets de la proteine ob

Also Published As

Publication number Publication date
WO1997040380A1 (fr) 1997-10-30
EP0914611A4 (fr) 2002-10-16
CA2252443A1 (fr) 1997-10-30
EP0914611A1 (fr) 1999-05-12

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