JP2000507819A - 遺伝子ｓｍ２２の上流の配列、これらの配列を含むベクター、および特に血管疾患の処置のためのそれらの治療的使用 - Google Patents
遺伝子ｓｍ２２の上流の配列、これらの配列を含むベクター、および特に血管疾患の処置のためのそれらの治療的使用Info
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- KXGVEGMKQFWNSR-LLQZFEROSA-N deoxycholic acid Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 KXGVEGMKQFWNSR-LLQZFEROSA-N 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
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- YQGOJNYOYNNSMM-UHFFFAOYSA-N eosin Chemical compound [Na+].OC(=O)C1=CC=CC=C1C1=C2C=C(Br)C(=O)C(Br)=C2OC2=C(Br)C(O)=C(Br)C=C21 YQGOJNYOYNNSMM-UHFFFAOYSA-N 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
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- 210000003754 fetus Anatomy 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
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- IRSCQMHQWWYFCW-UHFFFAOYSA-N ganciclovir Chemical compound O=C1NC(N)=NC2=C1N=CN2COC(CO)CO IRSCQMHQWWYFCW-UHFFFAOYSA-N 0.000 description 1
- 229960002963 ganciclovir Drugs 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000001415 gene therapy Methods 0.000 description 1
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- 239000003446 ligand Substances 0.000 description 1
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- 238000003468 luciferase reporter gene assay Methods 0.000 description 1
- 239000006166 lysate Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
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- 210000004379 membrane Anatomy 0.000 description 1
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- 210000003975 mesenteric artery Anatomy 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
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- 210000002464 muscle smooth vascular Anatomy 0.000 description 1
- DILRJUIACXKSQE-UHFFFAOYSA-N n',n'-dimethylethane-1,2-diamine Chemical compound CN(C)CCN DILRJUIACXKSQE-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
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- 102000020233 phosphotransferase Human genes 0.000 description 1
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- -1 potassium ferricyanide Chemical compound 0.000 description 1
- 239000000276 potassium ferrocyanide Substances 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
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- 238000010998 test method Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- XOGGUFAVLNCTRS-UHFFFAOYSA-N tetrapotassium;iron(2+);hexacyanide Chemical compound [K+].[K+].[K+].[K+].[Fe+2].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] XOGGUFAVLNCTRS-UHFFFAOYSA-N 0.000 description 1
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- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
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- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4716—Muscle proteins, e.g. myosin, actin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Vascular Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9603750A FR2746815A1 (fr) | 1996-03-26 | 1996-03-26 | Sequences en amont du gene sm 22, vecteurs les contenant et leurs utilisations therapeutiques, notamment dans le traitement des maladies vasculaires |
| FR96/03750 | 1996-03-26 | ||
| PCT/FR1997/000543 WO1997035974A1 (fr) | 1996-03-26 | 1997-03-26 | Sequences en amont du gene sm22, vecteurs les contenant et leurs utilisations therapeutiques, notamment dans le traitement des maladies vasculaires |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2000507819A true JP2000507819A (ja) | 2000-06-27 |
Family
ID=9490554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9534091A Pending JP2000507819A (ja) | 1996-03-26 | 1997-03-26 | 遺伝子ｓｍ２２の上流の配列、これらの配列を含むベクター、および特に血管疾患の処置のためのそれらの治療的使用 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0914426A1 (fr) |
| JP (1) | JP2000507819A (fr) |
| AU (1) | AU2390797A (fr) |
| CA (1) | CA2250099A1 (fr) |
| FR (1) | FR2746815A1 (fr) |
| WO (1) | WO1997035974A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9146232B2 (en) | 2008-12-19 | 2015-09-29 | Jnc Corporation | Method for stabilizing protein |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7169764B1 (en) | 1995-10-05 | 2007-01-30 | Arch Development Corporation | Promoter for smooth muscle cell expression |
| US6090618A (en) | 1996-10-07 | 2000-07-18 | Arch Development Corporation | DNA constructs and viral vectors comprising a smooth muscle promoter |
| WO2003083105A1 (fr) * | 2002-03-28 | 2003-10-09 | Medicalseed Co., Ltd. | Traitement et prevention de l'angiostenose |
| DK1648931T3 (da) | 2003-07-21 | 2011-03-07 | Transgene Sa | Multifunktionelle cytokiner |
| EP2476703A1 (fr) | 2011-01-14 | 2012-07-18 | Bracco Imaging S.p.A | Anticorps humains à réaction croisée avec des antigènes bactériens et propres de plaques athérosclérotiques |
| WO2012095516A1 (fr) | 2011-01-14 | 2012-07-19 | Bracco Imaging Spa | Anticorps humain à réaction croisée avec un antigène bactérien et un auto-antigène de plaques athéroscléreuses |
| EP2912069B1 (fr) | 2012-10-23 | 2019-07-31 | Emory University | Conjugués de gm-csf et d'il-4, compositions et procédés associés |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0174608A1 (fr) * | 1984-09-13 | 1986-03-19 | The Board Of Trustees Of The Leland Stanford Junior University | Gène de bêta-actine et éléments régulateurs, leur préparation et utilisation |
| JPH0779703B2 (ja) * | 1989-12-28 | 1995-08-30 | 東洋紡績株式会社 | リポプロテインリパーゼの遺伝情報を有するｄｎａ |
| FR2699191B1 (fr) * | 1992-12-16 | 1995-02-10 | Univ Paris Curie | Nouveaux vecteurs rétroviraux, lignées cellulaires les contenant, et leur utilisation dans le traitement des tumeurs. |
| FR2709761B1 (fr) * | 1993-09-10 | 1995-11-24 | Pasteur Institut | Procédé de détection de molécules contenant des mésappariements nucléotidiques et de localisation de ces mésappariements, et application à la détection de substitutions ou de délétions de bases . |
| FR2710846B1 (fr) * | 1993-10-04 | 1995-12-22 | Rhone Poulenc Rorer Sa | Compositions pharmaceutiques et leur utilisation, notamment dans le traitement des maladies neurogénératives. |
| EP0802792A1 (fr) * | 1994-01-14 | 1997-10-29 | Mallinckrodt Medical, Inc. | Traitement therapeutique visant a inhiber la restenose vasculaire |
| AU689214B2 (en) * | 1994-02-01 | 1998-03-26 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Fusion proteins that include antibody and nonantibody portions |
-
1996
- 1996-03-26 FR FR9603750A patent/FR2746815A1/fr not_active Withdrawn
-
1997
- 1997-03-26 EP EP97919424A patent/EP0914426A1/fr not_active Withdrawn
- 1997-03-26 CA CA002250099A patent/CA2250099A1/fr not_active Abandoned
- 1997-03-26 WO PCT/FR1997/000543 patent/WO1997035974A1/fr not_active Application Discontinuation
- 1997-03-26 JP JP9534091A patent/JP2000507819A/ja active Pending
- 1997-03-26 AU AU23907/97A patent/AU2390797A/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9146232B2 (en) | 2008-12-19 | 2015-09-29 | Jnc Corporation | Method for stabilizing protein |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0914426A1 (fr) | 1999-05-12 |
| AU2390797A (en) | 1997-10-17 |
| CA2250099A1 (fr) | 1997-10-02 |
| WO1997035974A1 (fr) | 1997-10-02 |
| FR2746815A1 (fr) | 1997-10-03 |
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