JP2000507588A5 - - Google Patents

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Publication number
JP2000507588A5
JP2000507588A5 JP1997535525A JP53552597A JP2000507588A5 JP 2000507588 A5 JP2000507588 A5 JP 2000507588A5 JP 1997535525 A JP1997535525 A JP 1997535525A JP 53552597 A JP53552597 A JP 53552597A JP 2000507588 A5 JP2000507588 A5 JP 2000507588A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1997535525A
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English (en)
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JP2000507588A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/005274 external-priority patent/WO1997036580A1/en
Publication of JP2000507588A publication Critical patent/JP2000507588A/ja
Publication of JP2000507588A5 publication Critical patent/JP2000507588A5/ja
Ceased legal-status Critical Current

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Description

Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
Figure 2000507588
JP9535525A 1996-03-29 1997-03-27 プロテアーゼインヒビターとしてのアミジノヒドラゾン Ceased JP2000507588A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1431796P 1996-03-29 1996-03-29
US60/014,317 1996-03-29
PCT/US1997/005274 WO1997036580A1 (en) 1996-03-29 1997-03-27 Amidinohydrazones as protease inhibitors

Publications (2)

Publication Number Publication Date
JP2000507588A JP2000507588A (ja) 2000-06-20
JP2000507588A5 true JP2000507588A5 (ja) 2004-12-02

Family

ID=21764747

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9535525A Ceased JP2000507588A (ja) 1996-03-29 1997-03-27 プロテアーゼインヒビターとしてのアミジノヒドラゾン

Country Status (10)

Country Link
US (1) US5891909A (ja)
EP (1) EP0906091B1 (ja)
JP (1) JP2000507588A (ja)
AT (1) ATE341317T1 (ja)
AU (1) AU722161B2 (ja)
CA (1) CA2250426C (ja)
DE (1) DE69736777T2 (ja)
ES (1) ES2273365T3 (ja)
NZ (1) NZ332073A (ja)
WO (1) WO1997036580A1 (ja)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW499412B (en) 1996-11-26 2002-08-21 Dimensional Pharm Inc Aminoguanidines and alkoxyguanidines as protease inhibitors
ATE344246T1 (de) 1997-11-26 2006-11-15 Ortho Mcneil Pharm Inc Heteroaryl aminoguanidin- und alkoxyguanidinderivate und ihre verwendung als proteasehemmer
US6344486B1 (en) * 1998-04-03 2002-02-05 3-Dimensional Pharmaceuticals, Inc. Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors
NZ508005A (en) 1998-04-24 2003-05-30 Dimensional Pharm Inc Amino acid amidinohydrazones, alkoxyguanidines and aminoguanidines useful as serine protease inhibitors
DK1086122T3 (da) 1998-06-11 2006-01-09 Johnson & Johnson Pharm Res Pyrazinonproteaseinhibitorer
FR2786181B1 (fr) * 1998-11-24 2001-10-26 Hoechst Marion Roussel Inc Nouveaux derives d'iminoguanidines, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
WO2000038683A1 (en) * 1998-12-23 2000-07-06 Du Pont Pharmaceuticals Company THROMBIN OR FACTOR Xa INHIBITORS
EP1194428B1 (en) 1999-07-09 2003-09-17 3-Dimensional Pharmaceuticals, Inc. Heteroaryl protease inhibitors and diagnostic imaging agents
JP2003509409A (ja) * 1999-09-13 2003-03-11 ３−ディメンショナル ファーマシューティカルズ， インコーポレイテッド アザシクロアルカノンセリンプロテアーゼ阻害剤
AU2001278927A1 (en) 2000-07-17 2002-01-30 3-Dimensional Pharmaceuticals, Inc. Cyclic oxyguanidine pyrazinones as protease inhibitors
EP1307432A1 (en) 2000-08-04 2003-05-07 3-Dimensional Pharmaceuticals, Inc. Cyclic oxyguanidine protease inhibitors
US6486174B2 (en) 2000-08-07 2002-11-26 3-Dimensional Pharmaceuticals, Inc. Tetrahydroisoquinoline-3-carboxylic acid alkoxyguanidines as integrin antagonists
US6589504B1 (en) * 2000-09-22 2003-07-08 Pharmacia & Upjohn Company Compounds and methods for diagnosing and treating amyloid-related conditions
CA2445160A1 (en) * 2001-04-24 2002-10-31 Aryx Therapeutics Coumarin derivatives to be used as anticoagulants
CA2465115A1 (en) 2001-11-06 2003-05-15 Wyeth Process for the preparation of 2-[alkyl(aryl)]sulfonylbenzene-sulfonyl chlorides and their intermediates
CN100513398C (zh) 2002-12-03 2009-07-15 Axys药物公司 作为因子viia抑制剂的2-(2-羟基联苯-3-基)-1h-苯并咪唑-5-甲脒衍生物
US7276608B2 (en) 2003-07-11 2007-10-02 Bristol-Myers Squibb Company Tetrahydroquinoline derivatives as cannabinoid receptor modulators
GB0507577D0 (en) * 2005-04-14 2005-05-18 Novartis Ag Organic compounds
US20070086958A1 (en) * 2005-10-14 2007-04-19 Medafor, Incorporated Formation of medically useful gels comprising microporous particles and methods of use
US20070087061A1 (en) * 2005-10-14 2007-04-19 Medafor, Incorporated Method and composition for creating and/or activating a platelet-rich gel by contact with a porous particulate material, for use in wound care, tissue adhesion, or as a matrix for delivery of therapeutic components
US7893080B2 (en) 2006-10-20 2011-02-22 Neurendo Pharma, Llc Method of restoring the incretin effect
RU2353619C2 (ru) * 2007-06-28 2009-04-27 Общество С Ограниченной Ответственностью "Бионика" Новые соединения, обладающие функцией антикоагулянтов, фармацевтические композиции на их основе для лечения тромботических состояний и плазмозамещающий раствор для коррекции гиперкоагуляционных нарушений при гемодилюции
RU2354647C2 (ru) * 2007-06-28 2009-05-10 Общество С Ограниченной Ответственностью "Бионика" Новые соединения, обладающие функцией ингибиторов тромбина, и фармацевтические композиции на их основе
GB0815784D0 (en) * 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
WO2012091757A1 (en) 2010-12-31 2012-07-05 Corridor Pharmaceuticals, Inc. Arginase inhibitors and methods of use thereof
EP3209641A4 (en) * 2014-05-05 2018-06-06 Lycera Corporation Benzenesulfonamido and related compounds for use as agonists of ror and the treatement of disease
US10034871B2 (en) 2014-11-07 2018-07-31 Regents Of The University Of Minnesota Salts and compositions useful for treating disease
CN110407721A (zh) * 2019-08-13 2019-11-05 上海毕得医药科技有限公司 一种4-氰基-3-(三氟甲基)苯-1-磺酰氯的合成方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3131218A (en) * 1961-02-15 1964-04-28 Smith Kline French Lab N-amino guanidine derivatives
US3271448A (en) * 1961-11-21 1966-09-06 Pfizer & Co C Phenoxyalkyl aminoguanidines
DE1263762B (de) * 1964-04-20 1968-03-21 Bayer Ag Verfahren zur Herstellung von Steroidguanylhydrazonen
BE663481A (ja) * 1964-05-05
US3413303A (en) * 1965-09-27 1968-11-26 Ciba Geigy Corp Aralkenyloxyguanidines
FR2390954A1 (fr) * 1976-10-13 1978-12-15 Choay Sa Nouvelles guanylhydrazones, leurs procedes de preparation et medicaments les contenant
FR2549049B1 (fr) * 1983-07-13 1986-06-20 Chauvin Blache Lab Nouvelles amidines, leur procede de preparation et leur application therapeutique
US4499082A (en) * 1983-12-05 1985-02-12 E. I. Du Pont De Nemours And Company α-Aminoboronic acid peptides
US4727064A (en) * 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
US4824849A (en) * 1985-06-03 1989-04-25 Merck & Co., Inc. α2 -adrenoceptor antagonistic arylquinolizines
US5002935A (en) * 1987-12-30 1991-03-26 University Of Florida Improvements in redox systems for brain-targeted drug delivery
FR2669927B1 (fr) * 1990-11-29 1994-04-08 Adir Cie Nouveaux derives de guanidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5466811A (en) * 1994-07-18 1995-11-14 Merck & Co., Inc. Dioxolenylmethyl carbamates pro moieties for amine drugs

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