JP2000506723A5 - - Google Patents

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Publication number
JP2000506723A5
JP2000506723A5 JP1997529893A JP52989397A JP2000506723A5 JP 2000506723 A5 JP2000506723 A5 JP 2000506723A5 JP 1997529893 A JP1997529893 A JP 1997529893A JP 52989397 A JP52989397 A JP 52989397A JP 2000506723 A5 JP2000506723 A5 JP 2000506723A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997529893A
Other languages
English (en)
Japanese (ja)
Other versions
JP4574750B2 (ja
JP2000506723A (ja
Filing date
Publication date
Priority claimed from GBGB9603507.6A external-priority patent/GB9603507D0/en
Application filed filed Critical
Publication of JP2000506723A publication Critical patent/JP2000506723A/ja
Publication of JP2000506723A5 publication Critical patent/JP2000506723A5/ja
Application granted granted Critical
Publication of JP4574750B2 publication Critical patent/JP4574750B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP52989397A 1996-02-20 1997-02-20 抗体変異物 Expired - Lifetime JP4574750B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9603507.6 1996-02-20
GBGB9603507.6A GB9603507D0 (en) 1996-02-20 1996-02-20 Antibody variants
PCT/GB1997/000472 WO1997031024A1 (en) 1996-02-20 1997-02-20 Antibody variants

Publications (3)

Publication Number Publication Date
JP2000506723A JP2000506723A (ja) 2000-06-06
JP2000506723A5 true JP2000506723A5 (enExample) 2004-11-25
JP4574750B2 JP4574750B2 (ja) 2010-11-04

Family

ID=10789047

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52989397A Expired - Lifetime JP4574750B2 (ja) 1996-02-20 1997-02-20 抗体変異物

Country Status (11)

Country Link
US (2) US20020048578A1 (enExample)
EP (1) EP0970127B1 (enExample)
JP (1) JP4574750B2 (enExample)
AT (1) ATE373016T1 (enExample)
AU (1) AU723366B2 (enExample)
CA (1) CA2246715C (enExample)
DE (1) DE69738138T2 (enExample)
ES (1) ES2294793T3 (enExample)
GB (1) GB9603507D0 (enExample)
NZ (1) NZ331299A (enExample)
WO (1) WO1997031024A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU725609C (en) * 1995-08-18 2002-01-03 Morphosys Ag Protein/(poly)peptide libraries
US6037454A (en) * 1996-11-27 2000-03-14 Genentech, Inc. Humanized anti-CD11a antibodies
ATE384792T1 (de) 1998-11-18 2008-02-15 Genentech Inc Antikörpervarianten mit höheren bindungsaffinitäten im vergleich zu parentalen antikörpern
CA2423850C (en) 2000-10-09 2017-07-04 Isis Innovation Limited Therapeutic antibodies
US7465790B2 (en) 2000-10-09 2008-12-16 Isis Innovation, Inc. Therapeutic antibodies
US20040109855A1 (en) * 2002-07-23 2004-06-10 Herman Waldmann Therapeutic antibodies with reduced side effect
JPWO2004087210A1 (ja) * 2003-03-31 2006-06-29 麒麟麦酒株式会社 抗cd52抗体による調節性t細胞分化誘導・増殖方法およびそのための医薬組成物
NZ550815A (en) * 2004-05-19 2009-04-30 Immunocore Ltd Method of improving T cell receptors
JP2008532559A (ja) * 2005-03-19 2008-08-21 メディカル リサーチ カウンシル ウイルス感染の治療及び予防又は治療及び予防の改善
PE20070207A1 (es) * 2005-07-22 2007-03-09 Genentech Inc Tratamiento combinado de los tumores que expresan el her
CN101820898B (zh) * 2007-05-16 2013-10-30 中国抗体制药有限公司 互补决定区(CDRs)功能人源化
WO2009025846A2 (en) 2007-08-22 2009-02-26 The Regents Of The University Of California Activatable binding polypeptides and methods of identification and use thereof
RU2636046C2 (ru) 2009-01-12 2017-11-17 Сайтомкс Терапьютикс, Инк Композиции модифицированных антител, способы их получения и применения
EP2398494A4 (en) 2009-02-23 2015-10-28 Cytomx Therapeutics Inc Proproteins and their methods of use
JP5894912B2 (ja) 2009-05-13 2016-03-30 ジェンザイム・コーポレーション 抗ヒトcd52免疫グロブリン
US8685896B2 (en) 2009-05-29 2014-04-01 Morphosys Ag Collection and methods for its use
CN103237809B (zh) 2010-11-19 2016-09-07 莫佛塞斯公司 一个集合及其使用方法
GB201109238D0 (en) * 2011-06-01 2011-07-13 Antitope Ltd Antibodies
WO2013152011A1 (en) * 2012-04-02 2013-10-10 Ab Biosciences, Inc. Novel human control antibodies and uses therefor
US9120853B2 (en) 2012-04-27 2015-09-01 Cytomx Therapeutics, Inc. Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof
KR20150139955A (ko) 2013-04-09 2015-12-14 보스톤 바이오메디칼, 인크. 암 치료에 사용하기 위한 2-아세틸나프토[2,3-b]푸란-4,9-디온
WO2015066279A2 (en) 2013-10-30 2015-05-07 Cytomx Therapeutics, Inc. Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof
WO2015089283A1 (en) 2013-12-11 2015-06-18 Cytomx Therapeutics, Inc. Antibodies that bind activatable antibodies and methods of use thereof
US20160120158A1 (en) * 2014-11-03 2016-05-05 The Johns Hopkins University Compositions and methods for the study and treatment of acute kidney injury
BR112017026025A2 (pt) 2015-06-03 2018-08-14 Boston Biomedical Inc composições que compreendem um inibidor de stemness de câncer e um agente imunoterápico para uso no tratamento de câncer
US11299469B2 (en) 2016-11-29 2022-04-12 Sumitomo Dainippon Pharma Oncology, Inc. Naphthofuran derivatives, preparation, and methods of use thereof
US10646464B2 (en) 2017-05-17 2020-05-12 Boston Biomedical, Inc. Methods for treating cancer
WO2020223273A2 (en) 2019-04-30 2020-11-05 Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center Compositions and methods for modulation of antibody activity

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2216126B (en) * 1988-02-12 1992-06-03 Medical Res Council Antibodies to the antigen campath-1
US5846534A (en) * 1988-02-12 1998-12-08 British Technology Group Limited Antibodies to the antigen campath-1
US5858725A (en) * 1990-10-10 1999-01-12 Glaxo Wellcome Inc. Preparation of chimaeric antibodies using the recombinant PCR strategy
WO1994004679A1 (en) * 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
ATE174515T1 (de) * 1991-10-15 1999-01-15 Btg Int Ltd Verwendung eines cdw52-spezifischen antikörpers zur behandlung von durch t-zellen vermittelten gelenkentzündungen
GB9125768D0 (en) * 1991-12-04 1992-02-05 Hale Geoffrey Therapeutic method

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