JP2000327510A - Fungicide for agricultural and horticultural purposes - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain the subject fungicide that exhibits high activity against plant pathogenic microbes of both filamentous fungi and bacteria by allowing the agent to include tetrahydroxymethylphosphonium sulfate as an active ingredient. SOLUTION: The objective fungicide includes (A) tetrahydroxymethylphosphonium sulfate, when necessary, (B) an ergosterol biosynthesis inhibitor as active ingredients. In a preferred embodiment, the component B is 2-(4-fluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-trimethylsilyl-2- ppropanol or the like. The formulation ratio of the component B to the component A is (0.01-100 pts.wt., more preferably 0.2-5 pts.wt., per 1 pt.wt. of the component A. The fungicide can be formulated into paste, liquid, suspension, emulsion, wettable powder on the like. This fungicide is applied to the farm land preferably in an amout of 0.01-1,000 g per are as an active ingredient.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a fungicide for agricultural and horticultural use containing tetrahydroxymethylphosphonium sulfate as an active ingredient, and an agricultural and horticultural product containing tetrahydroxymethylphosphonium sulfate and an ergosterol biosynthesis inhibitor as active ingredients. Related to fungicides.

[0002]

2. Description of the Related Art In Japanese Patent Publication No. 5-50481, tetrahydroxymethylphosphonium sulfate is already known as a growth inhibitor for aquatic aquatic microorganisms, and is used for industrial cooling water, treated water and water as base materials. It is used to prevent microbial contamination of the product to be used.For example, it is described that it can be used as an aqueous microbial growth inhibitor in water-based products selected from weed killers or pesticides. No activity as an agricultural and horticultural fungicide against plant diseases is described. On the other hand, the plant disease fungi targeted by the agricultural and horticultural fungicide of the present invention does not grow in an aquatic environment, but is parasitic on a plant and proliferates. It is completely different.

On the other hand, ergosterol biosynthesis inhibitors are
Widely used as an agricultural and horticultural fungicide, rice, wheat,
For controlling disease of many crops such as vegetables and fruit trees, it can be treated by methods such as foliage application, seed treatment, soil application, and water surface application. However, in general, an ergosterol biosynthesis inhibitor is ineffective against bacteria such as seedling blight, and has an activity of controlling fungi such as stupid seedling disease. not enough.

[0004]

The present inventors have made intensive studies to overcome such problems, and as a result, tetrahydroxymethylphosphonium sulfate has been used as an agricultural and horticultural fungicide for both filamentous fungi and bacteria. It has been found that it exhibits high activity against plant pathogens, and by mixing an ergosterol biosynthesis inhibitor with tetrahydroxymethylphosphonium sulfate, a higher control effect at a lower concentration than when each is used alone, that is, The present inventors have found that a synergistic effect is exhibited, and completed the present invention.

[0005]

The present invention relates to tetrahydroxymethylphosphonium sulfate (hereinafter referred to as compound 1).
And ) As an active ingredient, and a fungicide for agricultural and horticultural use comprising tetrahydroxymethylphosphonium sulfate and an ergosterol biosynthesis inhibitor as active ingredients.

The ergosterol biosynthesis inhibitor used in the agricultural and horticultural fungicidal composition of the present invention includes, for example, 2- (4
A triazole fungicide such as -fluorophenyl) -1- (1H-1,2,4-triazol-1-yl) -3-trimethylsilyl-2-propanol, tebuconazole, triticonazole; and triflumizole; Perfurazoate, imidazole fungicides such as prochloraz, and the like, preferably 2- (4-fluorophenyl) -1- (1H-1,2,4-triazol-1-yl) -3-trimethylsilyl-2 -Propanol (hereinafter referred to as compound 2). Compound 2 is, for example, a compound described as compound No. 3 in JP-A-5-222060, and its production method is described in Example 2 of the publication.

In the fungicidal composition for agricultural and horticultural use of the present invention, the mixing ratio of the compound 1 and the ergosterol biosynthesis inhibitor can be changed within a relatively wide range. Ergosterol biosynthesis inhibitor
It is 0.01 to 100 parts by weight, preferably 0.2 to 5 parts by weight.

[0008]

BEST MODE FOR CARRYING OUT THE INVENTION The agricultural or horticultural fungicide or the agricultural or horticultural fungicidal composition of the present invention comprises, besides the above-mentioned compound 1 and ergosterol biosynthesis inhibitor, an auxiliary usually used in the field of agricultural chemical formulations. Can be contained.

Examples of the adjuvants include mineral fine powders such as clay, talc, calcium carbonate, white carbon and titanium dioxide; starch derivatives such as starch and esterified starch, dextrin, glucose, fructose and saccharose. Such saccharides; polyoxyethylene alkyl ether, polyoxyethylene alkyl allyl ether, oxyethylene / oxypropylene block copolymer, sorbitan fatty acid ester,
Nonionic surfactants such as polyoxyethylene sorbitan fatty acid esters; alkyl benzene sulfonates;
Alkyl naphthalene sulfonate, dioctyl sulfosuccinate, phosphoric acid or sulfate of polyoxyethylene alkyl or alkyl allyl ether, β-naphthalene sulfonic acid formalin condensate, lignin sulfonate, polycarboxylic acid type and / or polysulfone Acid type polymer surfactants, anionic surfactants such as condensed phosphates (sodium hexametaphosphate, sodium tripolyphosphate); alginic acid and its salts, carboxymethylcellulose and its salts, methylcellulose, polyvinyl alcohol, sodium polyacrylate Water-soluble polymer compounds such as water-soluble polysaccharides such as polyethylene oxide, polyvinylpyrrolidone, and xanthan gum; ethylene-vinyl chloride copolymer resin powder, ethylene-vinyl acetate copolymer powder,
Thermoplastic resin powders such as vinyl chloride resin powders, solvents such as ethylene glycol, propylene glycol, N-methylpyrrolidone, 3-methyl-3-methoxybutanol, dipropylene glycol; lower alkyls of parahydroxybenzoic acid (methyl, Ethyl, propyl, butyl) esters, 1,2-benzisothiazoline-3-
And antimicrobial agents such as ON (BIT).

The fungicide for agricultural and horticultural use or the fungicidal composition for agricultural and horticultural use of the present invention can be formulated by a known method. Examples thereof include pastes, liquids, suspensions, emulsions, wettable powders, water solvents, It can be made into a powder or a capsule made of a polymer substance.

The agricultural or horticultural fungicide or the agricultural or horticultural fungicidal composition of the present invention is prepared by applying the original drug substance or the above-mentioned preparation to a spray liquid without dilution or by diluting it with water or the like. It can be sprayed or dusted, sprayed or dusted on the water surface of a paddy field or the surface of soil, or mixed with soil, or can be applied to a rice seedling raising box. Furthermore,
When the preparation is used as a seed treating agent, for example, seed dressing treatment or seed immersion treatment can be performed.

The fungicide for agricultural and horticultural use or the fungicidal composition for agricultural and horticultural use of the present invention comprises other fungicides, insecticides, acaricides, nematicides,
Planting agents, herbicides, seed disinfectants, fertilizers or soil conditioners can be used with or without mixing at the same time or at intervals, especially for the purpose of enhancing germicidal efficacy, other fungicides or Can be mixed with pesticides. Fungicides used include, for example, benomyl, thiuram, hydroxyisoxazole, TPN and fludioxonil, and pesticides used include, for example, thiocyclam.

The application rate of the fungicide for agricultural or horticultural use or the fungicidal composition for agricultural or horticultural use according to the present invention is determined by the mixing ratio of active ingredients, weather conditions, formulation, application time, application method, application place, target disease, target place, etc. Although it depends on the amount of the active ingredient per are is usually 0.01 g to 1000 g, preferably 1 to 200 g
It is.

When the agricultural, horticultural fungicide or the agricultural or horticultural fungicidal composition of the present invention is applied after diluting the emulsion, wettable powder, suspending agent, solution, etc. with water, the concentration of the active ingredient applied is usually 0.0001. ~ 1
%, Preferably 0.001 to 0.5%.

The agricultural or horticultural fungicide of the present invention or the granule or powder of the agricultural or horticultural fungicidal composition can be applied as it is without any dilution.

When the fungicide for agricultural and horticultural use or the fungicidal composition for agricultural and horticultural use of the present invention is treated with seeds, the application rate of the active ingredient is usually 0.001 to 50 g per 1 kg of seed, preferably 0.01 to 50 g.
10 g, especially when seed immersion treatment, the concentration of the active ingredient in the immersion liquid is usually 0.001-1%, preferably,
It is 0.01 to 0.5%.

When the agricultural / horticultural fungicide or the agricultural / horticultural fungicidal composition of the present invention is subjected to soil treatment, the application rate of the active ingredient is usually 0.01 to 1000 g, preferably 0.1 g, per are.
~ 100g.

When the agricultural or horticultural fungicide or the agricultural or horticultural fungicidal composition of the present invention is treated in a nursery box, the application rate of the active ingredient is 3
Normally, 0.times.60 cm.times.3 cm per nursery box is 0.1 mL.
1 to 100 g, preferably 1 to 50 g.

When the agricultural and horticultural composition of the present invention is used in rice cultivation, the present composition is used from the time when rice seedlings are grown in a nursery box or from the time of preparation to the time after rice transplanting or harvesting. And the effect is long lasting.

When the agricultural and horticultural composition of the present invention is used in a fruit tree / vegetable scene, the present composition can be used in all the growth stages of each crop.

Hereinafter, the present invention will be described in more detail with reference to Examples and Test Examples, but the present invention is not limited thereto. In the examples, "parts" indicates% by weight unless otherwise specified.

[0022]

【Example】

[0023]

Example 1 Suspension Thorside PS75 (registered trademark, Albright & Inc.)
Made by Wilson. Compound 1 contained 75%. 33 parts. 25 parts in terms of compound 1), polyoxyethylene sorbitan monooleate (3 parts), carboxymethyl cellulose (CM
C) (3 parts) and water (remainder) were mixed and wet-ground to a particle size of 5 microns or less to obtain a suspension containing 25% of compound 1.

[0024]

Example 2 Suspension Thorside PS75 (registered trademark, Albright & Inc.)
Made by Wilson. Compound 1 contained 75%. 33 parts. Compound 2 (5 parts), Compound 2 (5 parts), polyoxyethylene sorbitan monooleate (3 parts), carboxymethyl cellulose (CMC) (3 parts) and water (remainder) were mixed to give a particle size of 5 parts. Wet milling to submicron yielded a suspension containing 25% of compound 1 and 5% of compound 2.

[0025]

Example 3 Suspension Thorside PS75 (registered trademark, Albright & Inc.)
Made by Wilson. Compound 1 contained 75%. 33 parts. 25 parts in terms of compound 1), compound 2 (10 parts), polyoxyethylene sorbitan monooleate (3 parts), carboxymethyl cellulose (CMC) (3 parts) and water (remainder) were mixed to give a particle size of 5 parts. Wet milling to submicron yielded a suspension containing 25% Compound 1 and 10% Compound 2.

[0026]

[Test Example 1] Rice seed treatment test (idiot disease) The suspension prepared according to Examples 1 to 3 was diluted with water,
A test solution having a predetermined concentration was obtained. Affected paddy (variety: Tan Ginbozu) inoculated with idiot disease fungus during the flowering period of the previous year was immersed in the above test solution for 24 hours, air-dried, immersed in water for further 4 days, and then raised in a seedling box (30 cm × The seeds were cultivated in a greenhouse. Three weeks later, the number of diseased seedlings of idiot disease was examined, the rate of diseased seedlings was determined, and the control value was calculated. Table 1 shows the results. In the following table, "-" indicates that there is no value, and Colby's expected value E is calculated by the formula

[0027]

[Equation 1] E = (X + Y) − (X × Y) ÷ 100 [where, X represents the control value (%) of one active ingredient, Y represents the control value (%) of the other active ingredient, and E Indicates the control value (%) expected for the combination of the two active ingredients. ] According to Colby's formula. In general, when two given active ingredients are mixed and processed, the effect actually measured is the expected value E calculated by the above Colby equation.
If it is larger than this, it is determined that the action of the combination of the two active ingredients is synergistic.

[0028]

[Table 1] Rice seed treatment test (idiot disease) ────────────────────────────────── Test Active ingredient Active ingredient concentration Control value (ppm) Measured value Colby's calculated value １ 1 Compound 1 + Compound 2 500 + 200 93.0 77.4 2 Compound 1 + Compound 2 500 + 100 86.2 66.2 3 Compound 1 2000 80.2 -4 Compound 1 1000 54.8 -5 Compound 1 500 41.7-------------- ----6 Compound 2 200 61.2 -7 Compound 2 100 42.0 -8 No treatment (Rice diseased seedling rate: 63.5%) ─────────────────────── ───────────

[0029]

[Test Example 2] Rice seed treatment test (fungal disease of seedling blight) Thorside PS75 (registered trademark, Albright &)
Made by Wilson. Compound 1 contained 75%. ) Was diluted with water to obtain a test solution having a predetermined concentration. Affected paddy (variety: Koshihikari), which was inoculated in advance with seedling dead bacterial bacterium under reduced pressure, was immersed in the test solution for 24 hours, air-dried, immersed in water for further 4 days, and then raised in a nursery box (30 cm × 60 cm × 3 cm). ) And cultivated in a greenhouse. Three weeks later, the number of seedlings that were infected with the bacterial wilt disease was examined to determine the rate of the diseased seedlings. Table 2 shows the results. For comparison, Techlead C (registered trademark) containing ipconazole and cupric hydroxide as active ingredients.
Kumiai Chemical) was used.

[0030]

[Table 2] Rice Seed Treatment Test (Bacterial Seedling Blight) Test number Active ingredient Active ingredient amount (ppm) Diseased seedling rate (%) ────────────────────────────────── １ 1 compound 1 2000 0 2 compound 1 1000 0 3 compound 1 800 0.24 compound 1 600 1.0------------------5 ipconazole + cupric hydroxide (comparative) 250 + 230 21.0 6 No treatment 88.0 ───────────────────────────────────

[0031]

[Test Example 3] Cabbage foliage spray test (black rot) Thorside PS75 (registered trademark, Albright &)
Made by Wilson. Compound 1 contained 75%. ) Was diluted with water to obtain a test solution having a predetermined concentration. The test solution was sprayed twice every 10 days onto cabbage cultivated in the open field in autumn. The cabbage black rot fungus suspension was spray-inoculated on the cabbage the day before the final spraying. Fourteen days after the last application, the disease incidence was investigated, and the control value was calculated. Table 3 shows the results.
Shown in As a comparison, Z Bordeaux (registered trademark: Tomonoaglica) containing basic copper sulfate as an active ingredient was used.

[0032]

[Table 3] Cabbage foliage spray test (black rot) ─────────────────────────────────── Test number Active ingredient Amount of active ingredient (ppm) Control value ─────────────────────────────────── 1 Compound 1 1000 78.0 2 Compound 1 500 71.5------------------3 Basic copper sulfate (comparison) 1450 61.3 4 No treatment (degree of disease: 95.2) ──────── ───────────────────────────

[0033]

[Test Example 4] Cucumber foliage spray test (anthrax) Thorside PS75 (registered trademark, Albright & Co., Ltd.)
Made by Wilson. Compound 1 contained 75%. ) Was diluted with water to obtain a test solution having a predetermined concentration. The test solution was sprayed on foliage every three days on cucumber grown in an autumn house.
Immediately after the first spraying, the cucumber was spray-inoculated with the cucumber anthrax spore suspension. Ten days after the final application, the degree of onset was investigated, and the control value was calculated. Table 4 shows the results. For comparison, dimandaisen water-dispersible powder (manufactured by Rohm and Haas Japan) containing manzeb as an active ingredient was used.

[0034]

[Table 4] Cucumber foliage spray test (anthrax disease) ──────────────────────────────────── Test number Active ingredient Amount of active ingredient (ppm) Control value ──────────────────────────────────── 1 Compound 1 1000 100.0 2 Compound 1 500 100.0-----------------3 Manzeb (comparison) 1250 90.4 4 No treatment (degree of disease: 73.2) ─────────── ─────────────────────────

[0035]

The fungicide for agricultural and horticultural use containing the tetrahydroxymethylphosphonium sulfate of the present invention as an active ingredient has a high control effect on various plant diseases. Agricultural and horticultural fungicides containing a sterol biosynthesis inhibitor as an active ingredient exhibit a high synergistic effect, can be expected to expand the application range, and are characterized in terms of reducing the amount of active ingredient to be applied and saving labor.

Examples of the plant disease in which the agricultural and horticultural fungicide of the present invention exerts an excellent effect include, for example, idiot disease of rice (Gibb
erella fujikuroi), seedling blight disease (Pseudomonas plan)
tarii), bacterial wilt (Pseudomonas glumae), blast (Pyricularia oryzae), Rhizoctonia sola
ni), baldness (Cochliobolus miyabeanus, Mycronect)
riella nivalis, Sphaerulina oryzina, Leptoshaeria
salvinii, Helminthosporium sigmodeum var.irregula
re), wheat powdery mildew (Erysiphe graminis), rust (Puccinia recondita, P.graminis, P.hordei, P.
striiformis), eye spot disease (Pseudocercosporella herpotr)
ichoides), strain rot (Rhizoctonia cerealis), naked smut (Ustilago tritici, U.nuda), brown patch (Rhizoctonia solani) such as mackerel, and scab of apple (Gymnos)
porangium yamadae), scab (Venturia inaquali)
s), powdery mildew (Podosphaera leucotricha), pear scab (Gymnosporangium asiaticum), powdery mildew (P
hyllactinia pyri), scab (Venturia nashicola),
Cabbage black rot (Pseudomonas campestris), cucumber anthracnose (Colletotrichum lagenarium), powdery mildew (Sphaerotheca fuliginea), cucumber spot bacterial disease (Ps
eudomonus syringae) and the like, and the efficacy spectrum of the present invention is not limited to these. However, the agricultural and horticultural fungicide and the agricultural and horticultural fungicidal composition of the present invention are particularly useful for rice germ disease and seedling. It is effective against seed-borne diseases of rice such as bacterial wilt, rice blast and blast.

Claims (3)

[Claims] 1. A fungicide for agricultural and horticultural use comprising tetrahydroxymethylphosphonium sulfate as an active ingredient. 2. A fungicide for agricultural and horticultural use comprising tetrahydroxymethylphosphonium sulfate and an ergosterol biosynthesis inhibitor as active ingredients. 3. The method of claim 2, wherein the ergosterol biosynthesis inhibitor is 2- (4-fluorophenyl) -1- (1H-1,2,4-triazol-1-yl) -3.
3. The fungicide for agricultural and horticultural use according to claim 2, which is -trimethylsilyl-2-propanol.