CN103503895B - A kind of Fungicidal composition containing pyrazole compound and triazole class compounds - Google Patents

A kind of Fungicidal composition containing pyrazole compound and triazole class compounds Download PDF

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CN103503895B
CN103503895B CN201210208204.5A CN201210208204A CN103503895B CN 103503895 B CN103503895 B CN 103503895B CN 201210208204 A CN201210208204 A CN 201210208204A CN 103503895 B CN103503895 B CN 103503895B
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composition
component
fungicidal composition
effect
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CN103503895A (en
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李志念
单中刚
司乃国
李淼
刘长令
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Shenyang Sinochem Agrochemicals R&D Co Ltd
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Shenyang Research Institute of Chemical Industry Co Ltd
Sinochem Corp
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Abstract

The invention discloses a kind of Fungicidal composition, containing A, B two kinds of active components, component A is selected from the compound shown in following general formula I: in formula: R 1be selected from H, 2-Cl, 2-CH 3, 2-OH, 4-Cl, 4-CH 3, 4-OCH 3, 4-OH, 2,4-2Cl or 2,4-2CH 3; R 2be selected from CH 3or C 2h 5; R 3be selected from H, Cl, CH 3or C 2h 5; Q is selected from structure Q as follows 1, Q 2or Q 3:

Description

A kind of Fungicidal composition containing pyrazole compound and triazole class compounds
Technical field
The invention belongs to disinfectant use in agriculture field, relate to the research of the double activated component agricultural bactericidal mixture preparation containing pyrazole compound, be specifically related to a kind of Fungicidal composition containing pyrazole compound and triazole class compounds.
Background technology
Bactericide azoles bacterium ester has efficiently, the bactericidal activity of wide spectrum, and structural formula of compound is as follows:
In the further research process of this compound, inventor finds that the isomer that generates in the preparation process of above-claimed cpd (and general formula compound) and analog (compound as shown in general formula I) thereof have good control efficiency to fungal diseases such as rice blast, powdery mildew, rust, banded sclerotial blight, downy mildew.
In formula: R 1be selected from H, 2-Cl, 2-CH 3, 2-OH, 4-Cl, 4-CH 3, 4-OCH 3, 4-OH, 2,4-2Cl or 2,4-2CH 3; R 2be selected from CH 3or C 2h 5; R 3be selected from H, Cl, CH 3or C 2h 5; Q is selected from structure Q as follows 1, Q 2or Q 3:
Bactericide uses history to show, reuses same class medicament for a long time, very easily makes the part bacterial strain of disease develop immunity to drugs, and drug effect is obviously declined.By the antimicrobial combination with the different mechanism of action being used, sometimes can being expanded the fungicidal spectrum of medicament, delay the drug-fast generation of pathogen, play the synergistic effect of combination medicament, extend the service life of medicament.
Summary of the invention
The object of the present invention is to provide a kind of is the Fungicidal composition of one of active component containing the pyrazole compound shown in general formula A, to improve the control efficiency to corps diseases.
By large quantity research and test, inventor determines with the suitable mixed ratio of pyrazole compound and triazole class compounds or its salt Fungicidal composition that is active component, obtain a kind of Fungicidal composition with outstanding synergistic effect, thus achieve object of the present invention, complete the present invention.
Technical scheme of the present invention is as follows:
A kind of Fungicidal composition, containing A, B two kinds of active components, the weight ratio between component A and B component two component is 1:100 ~ 100:1; In composition, the weight content of active component is 0.1 ~ 95%;
Component A is selected from the compound shown in following general formula I:
In formula: R 1be selected from H, 2-Cl, 2-CH 3, 2-OH, 4-Cl, 4-CH 3, 4-OCH 3, 4-OH, 2,4-2Cl or 2,4-2CH 3; R 2be selected from CH 3or C 2h 5; R 3be selected from H, Cl, CH 3or C 2h 5; Q is selected from structure Q as follows 1, Q 2or Q 3:
B component is selected from triazole bactericidal agent or its salt, described triazole bactericidal agent is selected from Tebuconazole B1, propiconazole B2, Difenoconazole B3, epoxiconazole B4, triazolone B5, Flusilazole B6, efficient olefin conversion B7, nitrile bacterium azoles B8, olefin conversion B9, penconazole B10, own azoles alcohol B11, Triadimenol B12, Cyproconazole B13, Fluquinconazole B14, Flutriafol B15, metconazole B16, glyoxalin B17, prothioconazoles B18, plant bacterium azoles B19, triticonazole B20, bitertanol B21, oxygen ring azoles B22, tetraconazole B23, imazalil B24 or efficient imazalil B25.
Biological activity test result shows, R in the compd A 1(in component A and general formula I 1=H, R 2=CH 3, R 3=CH 3, Q=Q 1compound) more excellent bactericidal effect is shown to various crop disease.Partial test the results are shown in Table 1-table 6.
Table 1 pyrazole compound A1 prevents and treats cucumber downy mildew effect (potted plant seedling)
Table 2 pyrazole compound A1 is to Phytophthora infestans germ sporangium Germination suppression effect
Table 3 pyrazole compound A1 prevents and treats wheat powdery mildew effect (potted plant seedling)
Table 4 pyrazole compound A1 prevents and treats cucumber anthracnose effect (potted plant seedling)
Table 5 pyrazole compound A1 prevents and treats Bean rust disease effect (potted plant seedling)
Table 6 pyrazole compound A1 is to magnaporthe grisea spore Germination suppression effect
Therefore, the present invention more preferably technical scheme is: in above-mentioned Fungicidal composition, and active component A is selected from compd A 1, and structural formula is as follows:
The present invention further preferred technical scheme is: in described Fungicidal composition,
Active component A is selected from compd A 1;
Active component B is selected from triazole bactericidal agent or its salt; Described triazole bactericidal agent is selected from Tebuconazole B1, propiconazole B2, Difenoconazole B3, epoxiconazole B4, triazolone B5, Flusilazole B6, efficient olefin conversion B7, nitrile bacterium azoles B8, olefin conversion B9, penconazole B10 or own azoles alcohol B11;
Weight ratio between A, B two kinds of active components is 1:50 ~ 50:1.
The present invention further preferred technical scheme is: in described Fungicidal composition,
Active component A is selected from compd A 1;
Active component B is selected from Tebuconazole B1, propiconazole B2, Difenoconazole B3, epoxiconazole B4, triazolone B5, Flusilazole B6, efficient olefin conversion B7 or nitrile bacterium azoles B8;
Weight ratio between A, B two kinds of active components is 1:20 ~ 20:1.
Present composition synergistic function is obvious, and the powdery mildew of the disease caused multiple disease fungus especially in Cereal (barley, wheat, corn, dogstail etc.), vegetables (as cucumber, beans etc.), fruit (apple, pears, strawberry etc.), ornamental plants, lawn and grape vine, rust, banded sclerotial blight, root rot, scab, (silk) smut etc. have good control efficiency.Therefore, technical scheme of the present invention also comprises the purposes that said composition is used as fungicide, as preparing fungicide medicine, for preventing and treating various plants pathogenic epiphyte disease.
When preparing the present composition, can be added other wherein to the effective active substance of pest, or there is active substance or the fertilizer of herbicide effect and growth regulating effect.
The present invention also comprises the using method of above-mentioned composition control harmful fungoid.Component A and at least one B component prepare in advance according to appropriate proportioning provided by the invention or are using extemporaneous preparation or using successively separately, all present significant protection effect or obviously expand disease control kind.
Fungicidal composition of the present invention is particularly suitable for preventing and treating following plants disease: powdery mildew of wheat and barley, wheat rust, Wheat sheath blight, stinking smut, wheat class root rot, maize head smut, head smut of sorghum, cucurbits powdery mildew, pepper powdery mildew, root rot, cotton seedling blight, apple mildew, pear scab, grape powdery mildew, Peanut Rust, powdery mildew of strawberry, coffee rust, oranges and tangerines powdery mildew, oranges and tangerines root rot, lawn powdery mildew, lawn fusarium wilt.
According to the occurrence degree of corps diseases, the working concentration of the present composition is 5 ~ 1500g/hm in proportion of crop planting region 2, preferably 20 ~ 500g/hm 2.
During process seed, the using dosage of composition is generally 1 ~ 1000g/100kg seed, preferably 5 ~ 200g/100kg seed.
Fungicidal composition of the present invention can be processed into the water-based or oily suspensions that directly use or be watered rear use, the multiple formulations such as powder, emulsion, oil dispersion, paste, paste, particle, fumicants.In all cases, use the guarantee present composition meticulous and equally distributed preparation.Above-mentioned various preparation all can be prepared in a known manner.Such as active component is mixed with solvent and/or carrier and prepares, if desired can add auxiliary agent and the surfactants such as emulsifier, dispersant, wetting agent.
Suitable solvent or auxiliary agent are mainly water, benzene, dimethylbenzene, toluene, alkylbenzene, aliphatic hydrocarbon, alcohols, ester class, ketone, also have vegetable oil and the molten fiber of methyl.Meanwhile, the mixture of different liquids is also applicable.
Suitable surfactant is lignin sulfonic acid, naphthalene sulfonic acids, phenolsulfonic acid, the alkali metal salt of dibutyl naphthalenesulfonic acid, alkali salt and ammonium salt, alkylaryl sulfonates, alkyl sulfate, alkylsulfonate, aliphatic alcohol sulfate etc.
Suitable wetting agent is sldium lauryl sulfate, lauryl sodium sulfate, dodecyl sodium sulfate, sodium alkyl benzene sulfonate, Negel, sorbitan fatty acid ester polyoxyethylene ether etc.
Powder formulation active substance can be mixed with solid carrier or together with grind to prepare.
Granular preparation can adhere to by making active component and solid carrier and prepare.
The present composition can be made into containing 0.1 ~ 95%(weight) preparation of active component, preferably containing 5 ~ 80%(weight) preparation of active component.
The example of preparing of certain formulations is listed below, and wherein said active component is pyrazole compound A in Fungicidal composition of the present invention and triazole class compounds B, and the suitable proportion between A, B two kinds of active components as previously mentioned.
Soluble liquid (SL)
By 10 parts of (weight ratio, lower with) active components in water-soluble or water-soluble solvent, be mixed with liquid preparation.Dilute with water obtains dispersion, for cauline leaf spraying or soil pouring.
Dispersible agent (DC)
20 parts of active components to be dissolved in cyclohexanone and to add PEF base pyrrolidones, being mixed with liquid preparation.Dilute with water obtains dispersion.
Missible oil (EC)
30 parts of active components to be dissolved in dimethylbenzene and to add calcium dodecyl benzene sulfonate and castor oil ethoxylate, being mixed with homogeneous liquid preparation.Dilute with water obtains emulsion, for cauline leaf spraying or soil pouring.
Aqueous emulsion (EW)
25 parts of active components to be dissolved in dimethylbenzene and to add calcium dodecyl benzene sulfonate and castor oil ethoxylate, by emulsifier, said composition being introduced in water, be mixed with liquid preparation.Dilute with water obtains emulsion, for cauline leaf spraying or soil pouring.
Suspending agent (SC)
In the ball mill stirred, 20 parts of active components pulverized and adds dispersant, wetting agent and water or organic solvent, obtaining active component suspension in small, broken bits.Dilute with water obtains suspension, for cauline leaf spraying or soil pouring.
Water dispersible granules (WG)
50 parts of active component grindings in small, broken bits are added dispersant and wetting agent, by extruder, spray tower, fluid bed, makes water dispersible or water-soluble granular.Dilute with water obtains dispersion or solution, for cauline leaf spraying or soil pouring.
Wetting powder (WP)
75 parts of active components ground in rotor-stator grinder and adds dispersant, wetting agent and silica gel, making powder preparation.Dilute with water obtains dispersion or solution, for cauline leaf spraying or soil pouring.
Example 8: pulvis (DP)
5 parts of active component grindings in small, broken bits are fully mixed to get the pulvis that can directly use with the kaolin in small, broken bits of 95 parts.
Example 9: granule (GR)
0.5 part of active component grinding in small, broken bits, in conjunction with the carrier of 99.5 parts, through extruder, spray dryer, is obtained granule.
Active component can directly or with its preparation by spraying, atomization, dusting, to broadcast sowing or pouring type uses.In addition, polytype oil, wetting agent, adjuvant, weed killer herbicide, fungicide, other agricultural chemicals can add in the present composition.These compositions mix with the weight ratio of 1:30 ~ 30:1 with the present composition usually.
Fungicidal composition of the present invention has good synergistic function, significantly improves the control efficiency to corps diseases.The antimicrobial combination with the different mechanism of action uses by the present invention, so not only expands the fungicidal spectrum of medicament, and can delay the drug-fast generation of pathogen, extend the service life of medicament.In agricultural production, the suitable proportion that two kinds of bactericide propose according to the present invention is used together, also can reach the effect of saving of work and time.
Embodiment
The synergistic function of the present composition to harmful fungoid is described further by the following example, but the present invention is only limitted to this absolutely not.Wherein said active component is compd A 1 and the triazole type part bactericide B of one of pyrazole compound in Fungicidal composition of the present invention.
Method of testing and evaluation method as follows:
By active ingredient matter sample acetone solution (volume ratio of amounts of acetone and spouting liquid is equal to or less than 0.05), dilutes with the water containing 0.1% Tween 80, be mixed with desired concn liquid to be measured, the another liquid to be measured by setting proportions composition.On crops sprayer, liquid to be measured is sprayed on disease host plant, after 24 hours, carry out disease inoculation.According to disease feature, cultivate being placed in climatic chamber after the disease plant inoculating needing temperature control moisturizing to cultivate, after disease completes and infects, immigration hot-house culture, the disease plant cultivated not needing moisturizing is directly cultivated at warm indoor inoculation.After contrasting fully morbidity, measure pathogen and infect Crop leaf area percentage, use Abbot formulae discovery, namely obtain observing effect (W):
W=（1-α/β）×100
In formula:
α: the fungal infection percentage of process crop;
β: the fungal infection percentage of untreated (blank) crop;
For " 0 ", effect represents that the level that infects of process crop is identical with the level that infects of untreated control crop; For " 100 ", effect represents that process crop is not infected.
The expection effect (calculating effect) of composition uses Colby formula (see R.S.Colby, weeds (Weeds), 1967,15,20-22) to determine, and compares with observation effect.
E=X+Y–XY/100
In formula:
E: the expection effect (the calculating effect in following table) when working concentration is the composition of the active component A of a and b and B, represents with the % of untreated control;
X: effect when working concentration is the active component A of a, represents with the % of untreated control;
Y: effect when working concentration is the active component B of b, represents with the % of untreated control.
When observing effect value and being greater than calculating effect value, represent that composition has synergistic effect; When observing effect value and equaling to calculate effect value, expression composition is adduction; When observing effect value and being less than calculating effect value, expression composition is antagonism.
Embodiment 1 prevents and treats wheat powdery mildew (Blumeria graminis) test
Be the aqueous solution (concentration is as described below) the spraying process of the potted plant two leaf phase wheat seedling active components in " the Liao Dynasty's spring 10 " by kind, after 24 hours, by the spore suspension inoculation test plants of wheat powdery mildew.Test plants to be placed in temperature be 24 ± 2 DEG C and relative moisture be 50 ± 5% climatic chamber cultivate, within 5 days, estimate the development degree of infection process on blade afterwards.The activity data of each independent active component and present composition control wheat powdery mildew the results are shown in Table 7 and table 8.The observation effect value of composition is all greater than calculating effect value, and composition shows as synergistic effect in test ratio range.
The activity of the independent active component of table 7
The activity of table 8 present composition
Tested number Composition Concentration (mg/L) Proportioning Observe effect (%) Calculate effect (%)
9 Compd A 1+ Tebuconazole B1 1.25 4:1 92.63 72.35
10 Compd A 1+ Tebuconazole B1 0.5 1:1 69.47 55.05
11 Compd A 1+ Tebuconazole B1 0.3125 1:4 44.21 33.45
12 Compd A 1+ propiconazole B2 1.25 4:1 87.37 71.64
13 Compd A 1+ propiconazole B2 0.5 1:1 76.84 53.90
14 Compd A 1+ propiconazole B2 0.3125 1:4 54.74 31.75
15 Compd A 1+ Difenoconazole B3 1.25 4:1 89.47 71.28
16 Compd A 1+ Difenoconazole B3 0.5 1:1 70.53 53.32
17 Compd A 1+ Difenoconazole B3 0.3125 1:4 48.42 30.89
18 Compd A 1+ triazolone B5 1.25 4:1 83.16 68.80
19 Compd A 1+ triazolone B5 0.5 1:1 70.53 49.29
20 Compd A 1+ triazolone B5 0.3125 1:4 40.00 24.92
21 The efficient olefin conversion B7 of compd A 1+ 1.25 4:1 85.26 70.22
22 The efficient olefin conversion B7 of compd A 1+ 0.5 1:1 69.47 51.59
23 The efficient olefin conversion B7 of compd A 1+ 0.3125 1:4 38.95 28.34
24 Compd A 1+ nitrile bacterium azoles B8 1.25 4:1 86.32 69.51
25 Compd A 1+ nitrile bacterium azoles B8 0.5 1:1 68.42 50.44
26 Compd A 1+ nitrile bacterium azoles B8 0.3125 1:4 38.95 26.63
Embodiment 2 prevents and treats powdery mildew of cucumber (Erysiphe cucurbitacearum) test
Be the aqueous solution (concentration is as described below) the spraying process of the potted plant two leaf phase cucumber seedling active components of " the close thorn in Shandong " by kind, after 24 hours, by the spore suspension inoculation test plants of cucumber powdery mildew's pathogen.Test plants to be placed in temperature be 24 ± 2 DEG C and relative moisture be 50 ± 5% greenhouse cultivate, within 8 days, estimate the development degree of infection process on blade afterwards.The activity data that each independent active component and the present composition prevent and treat powdery mildew of cucumber the results are shown in Table 9 and table 10.The observation effect value of composition is all greater than calculating effect value, and composition shows as synergistic effect in test ratio range.
The activity of the independent active component of table 9
The activity of table 10 present composition
Tested number Composition Concentration (mg/L) Proportioning Observe effect (%) Calculate effect (%)
35 Compd A 1+ Tebuconazole B1 21 20:1 78.49 53.94
36 Compd A 1+ Tebuconazole B1 6 5:1 55.91 35.70
37 Compd A 1+ Tebuconazole B1 2 1:1 38.71 25.15
38 Compd A 1+ Tebuconazole B1 1.2 1:5 29.03 14.59
39 Compd A 1+ Tebuconazole B1 1.05 1:20 18.28 10.75
40 Compd A 1+ propiconazole B2 21 20:1 76.34 51.72
41 Compd A 1+ propiconazole B2 6 5:1 52.69 32.61
42 Compd A 1+ propiconazole B2 2 1:1 32.26 21.54
43 Compd A 1+ propiconazole B2 1.2 1:5 24.73 10.47
44 Compd A 1+ propiconazole B2 1.05 1:20 15.05 6.45
45 Compd A 1+ Difenoconazole B3 21 20:1 77.42 52.83
46 Compd A 1+ Difenoconazole B3 6 5:1 51.61 34.15
47 Compd A 1+ Difenoconazole B3 2 1:1 37.63 23.34
48 Compd A 1+ Difenoconazole B3 1.2 1:5 25.81 12.53
49 Compd A 1+ Difenoconazole B3 1.05 1:20 17.20 8.60
50 Compd A 1+ epoxiconazole B4 21 20:1 82.80 54.49
51 Compd A 1+ epoxiconazole B4 6 5:1 58.06 36.48
52 Compd A 1+ epoxiconazole B4 2 1:1 39.78 26.05
53 Compd A 1+ epoxiconazole B4 1.2 1:5 29.03 15.62
54 Compd A 1+ epoxiconazole B4 1.05 1:20 19.35 11.83
55 The efficient olefin conversion B7 of compd A 1+ 21 20:1 75.27 50.61
56 The efficient olefin conversion B7 of compd A 1+ 6 5:1 51.61 31.06
57 The efficient olefin conversion B7 of compd A 1+ 2 1:1 29.03 19.74
58 The efficient olefin conversion B7 of compd A 1+ 1.2 1:5 18.28 8.42
59 The efficient olefin conversion B7 of compd A 1+ 1.05 1:20 12.90 4.30
60 Compd A 1+ nitrile bacterium azoles B8 21 20:1 79.57 53.38
61 Compd A 1+ nitrile bacterium azoles B8 6 5:1 54.84 34.93
62 Compd A 1+ nitrile bacterium azoles B8 2 1:1 36.56 24.45
63 Compd A 1+ nitrile bacterium azoles B8 1.2 1:5 24.73 13.56
64 Compd A 1+ nitrile bacterium azoles B8 1.05 1:20 16.13 9.68
Embodiment 3 prevents and treats wheat rust (Puccinia recondita tritici) test
Be the aqueous solution (concentration is as described below) the spraying process of the potted plant two leaf phase wheat seedling active components in " the Liao Dynasty's spring 10 " by kind, after 24 hours, be inoculated in test plants with the spore suspension of wheat rust bacterium.Test plants being placed in 22 ~ 24 DEG C with relative moisture is that 85 ~ 90% climatic chambers are cultivated 20 hours, then moves into hot-house culture (temperature is 24 ± 2 DEG C, and relative moisture is 50 ± 5%), within 7 days, estimates the development degree of infection process on blade afterwards.The activity data that each independent active component and the present composition prevent and treat wheat rust the results are shown in Table 11 and table 12.The observation effect value of composition is all greater than calculating effect value, and composition shows as synergistic effect in test ratio range.
The activity of the independent active component of table 11
The activity of table 12 present composition
Tested number Composition Concentration (mg/L) Proportioning Observe effect (%) Calculate effect (%)
72 Compd A 1+ Tebuconazole B1 2.5 4:1 87.50 77.14
73 Compd A 1+ Tebuconazole B1 1 1:1 76.14 62.67
74 Compd A 1+ Tebuconazole B1 0.625 1:4 55.68 45.90
75 Compd A 1+ propiconazole B2 2.5 4:1 81.82 72.50
76 Compd A 1+ propiconazole B2 1 1:1 69.32 55.08
77 Compd A 1+ propiconazole B2 0.625 1:4 44.32 34.91
78 Compd A 1+ epoxiconazole B4 2.5 4:1 90.91 78.69
79 Compd A 1+ epoxiconazole B4 1 1:1 78.41 65.20
80 Compd A 1+ epoxiconazole B4 0.625 1:4 57.95 49.58
81 Compd A 1+ triazolone B5 2.5 4:1 80.68 70.95
82 Compd A 1+ triazolone B5 1 1:1 63.64 52.54
83 Compd A 1+ triazolone B5 0.625 1:4 48.86 31.24
84 The efficient olefin conversion B7 of compd A 1+ 2.5 4:1 82.95 73.66
85 The efficient olefin conversion B7 of compd A 1+ 1 1:1 65.91 56.98
86 The efficient olefin conversion B7 of compd A 1+ 0.625 1:4 54.55 37.66
Embodiment 4 prevents and treats wheat sharp eyespot (Rhizoctonia cereas) test
Be the aqueous solution (concentration is as described below) the spraying process of the potted plant two leaf phase wheat seedling active components in " the Liao Dynasty's spring 10 " by kind, after 24 hours, be inoculated in test plants with wheat sharp eyespot mycelium.Test plants being placed in 24 ~ 26 DEG C with relative moisture is that 80 ~ 85% climatic chambers are cultivated.After 5 days, the development degree of infection process on range estimation leaf sheath.The activity data of each independent active component and present composition control wheat sharp eyespot the results are shown in Table 13 and table 14.The observation effect value of composition is all greater than calculating effect value, and composition shows as synergistic effect in test ratio range.
The activity of the independent active component of table 13
The activity of table 14 present composition
Tested number Composition Concentration (mg/L) Proportioning Observe effect (%) Calculate effect (%)
92 Compd A 1+ Difenoconazole B3 5 4:1 82.14 63.82
93 Compd A 1+ Difenoconazole B3 2 1:1 63.10 45.24
94 Compd A 1+ Difenoconazole B3 1.25 1:4 39.29 29.60
95 Compd A 1+ epoxiconazole B4 5 4:1 86.90 65.91
96 Compd A 1+ epoxiconazole B4 2 1:1 67.86 48.41
97 Compd A 1+ epoxiconazole B4 1.25 1:4 46.43 33.68
98 Compd A 1+ triazolone B5 5 4:1 77.38 60.14
99 Compd A 1+ triazolone B5 2 1:1 52.38 39.68
100 Compd A 1+ triazolone B5 1.25 1:4 33.33 22.45
Embodiment 5 prevents and treats scab of cucumber (Scolicotrichum melophthorum) test
Be the aqueous solution (concentration is as described below) the spraying process of the potted plant two leaf phase cucumber seedling active components of " the close thorn in Shandong " by kind, after 24 hours, by the spore suspension inoculation test plants of dosporium cucumerinumand its.Test plants to be placed in temperature be 24 ± 2 DEG C and relative moisture is that 85 ~ 90% climatic chambers are cultivated 24 hours, then moves into hot-house culture (temperature is 24 ± 2 DEG C, and relative moisture is 50 ± 5%), within 6 days, estimates the development degree of infection process on blade afterwards.The activity data that each independent active component and the present composition prevent and treat scab of cucumber the results are shown in Table 15 and table 16.The observation effect value of composition is all greater than calculating effect value, and composition shows as synergistic effect in test ratio range.
The activity of the independent active component of table 15
The activity of table 16 present composition
Tested number Composition Concentration (mg/L) Proportioning Observe effect (%) Calculate effect (%)
105 Compd A 1+ Flusilazole B6 21 20:1 85.39 66.37
106 Compd A 1+ Flusilazole B6 6 5:1 68.54 49.10
107 Compd A 1+ Flusilazole B6 2 1:1 52.81 37.28
108 Compd A 1+ Flusilazole B6 1.2 1:5 44.94 30.92
109 Compd A 1+ Flusilazole B6 1.05 1:20 35.96 24.55
110 Compd A 1+ nitrile bacterium azoles B8 21 20:1 83.15 65.44
111 Compd A 1+ nitrile bacterium azoles B8 6 5:1 65.17 47.68
112 Compd A 1+ nitrile bacterium azoles B8 2 1:1 47.19 35.54
113 Compd A 1+ nitrile bacterium azoles B8 1.2 1:5 39.33 29.00
114 Compd A 1+ nitrile bacterium azoles B8 1.05 1:20 31.46 22.46

Claims (4)

1. a Fungicidal composition, containing A, B two kinds of active components, the weight ratio between component A and B component two component is 1:20 ~ 20:1; In composition, the weight content of active component is 0.1 ~ 95%;
Component A is selected from A1, and structural formula is as follows:
Active component B is selected from triazole bactericidal agent or its salt; Described triazole bactericidal agent is selected from Tebuconazole B1, propiconazole B2, Difenoconazole B3, epoxiconazole B4, triazolone B5, Flusilazole B6, efficient olefin conversion B7 or nitrile bacterium azoles B8.
2. Fungicidal composition according to claim 1, is characterized in that: composition is mixed with water-based or oily suspensions, powder, emulsion, oil dispersion, paste, paste, particle, fumicants.
3. a purposes for Fungicidal composition, is characterized in that: Fungicidal composition is as preparing fungicide medicine as claimed in claim 1, for preventing and treating plant pathogenic fungi disease.
4. the purposes of Fungicidal composition according to claim 3, is characterized in that: for preventing and treating plant powdery mildew, rust, banded sclerotial blight, root rot, scab, head smut.
CN201210208204.5A 2012-06-19 2012-06-19 A kind of Fungicidal composition containing pyrazole compound and triazole class compounds Active CN103503895B (en)

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CN104186485A (en) * 2014-09-22 2014-12-10 江苏省绿盾植保农药实验有限公司 Microbicide composition for preventing and controlling wheat powdery mildew and application of composition
CN104336036B (en) * 2014-10-14 2017-04-12 沈阳中化农药化工研发有限公司 Fungicidal composition and application thereof

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CN1657524A (en) * 2004-02-20 2005-08-24 沈阳化工研究院 Substituted azole compounds and their preparation and application
CN1869034A (en) * 2005-05-26 2006-11-29 沈阳化工研究院 An arylether kind compound and its preparation and application
CN101406191A (en) * 2007-10-09 2009-04-15 中国中化集团公司 Fungicidal compositions
WO2010021121A1 (en) * 2008-08-18 2010-02-25 三井化学アグロ株式会社 Plant disease control agent comprising d-tagatose as active ingredient, and plant disease control method
CN102106355A (en) * 2009-12-23 2011-06-29 中国中化股份有限公司 Antifungal composition containing pyraoxystrobin

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CN1657524A (en) * 2004-02-20 2005-08-24 沈阳化工研究院 Substituted azole compounds and their preparation and application
CN1869034A (en) * 2005-05-26 2006-11-29 沈阳化工研究院 An arylether kind compound and its preparation and application
CN101406191A (en) * 2007-10-09 2009-04-15 中国中化集团公司 Fungicidal compositions
WO2010021121A1 (en) * 2008-08-18 2010-02-25 三井化学アグロ株式会社 Plant disease control agent comprising d-tagatose as active ingredient, and plant disease control method
CN102106355A (en) * 2009-12-23 2011-06-29 中国中化股份有限公司 Antifungal composition containing pyraoxystrobin

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