JP2000264833A - Skin cosmetic - Google Patents

Skin cosmetic

Info

Publication number
JP2000264833A
JP2000264833A JP11074344A JP7434499A JP2000264833A JP 2000264833 A JP2000264833 A JP 2000264833A JP 11074344 A JP11074344 A JP 11074344A JP 7434499 A JP7434499 A JP 7434499A JP 2000264833 A JP2000264833 A JP 2000264833A
Authority
JP
Japan
Prior art keywords
skin
ceramide
cosmetic
effect
parsley
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11074344A
Other languages
Japanese (ja)
Inventor
Masanori Uda
正紀 宇田
Tatsu Miyamoto
達 宮本
Takao Ishida
隆男 石田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fancl Corp
Original Assignee
Fancl Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fancl Corp filed Critical Fancl Corp
Priority to JP11074344A priority Critical patent/JP2000264833A/en
Publication of JP2000264833A publication Critical patent/JP2000264833A/en
Pending legal-status Critical Current

Links

Landscapes

  • Cosmetics (AREA)

Abstract

PROBLEM TO BE SOLVED: To obtain the subject cosmetic having excellent moisturizing effect, rough skin improving effect, senility preventive effect and skin condition- improving effect, and useful as a facial cleansing cosmetic, lotion, milky lotion or the like, by including parsley essence and a ceramide and/or the like. SOLUTION: This skin cosmetic is obtained by including (A) pref. 0.001-10.0 wt.%, more pref. 0.01-2.0 wt.%, of essence extracted from parsley and (B) pref. 0.001-5.0 wt.%, more pref. 0.01-2.0 wt.%, of one or two kind(s) of ingredients selected from glycoceramides such as a ceramide and a glucoceramide. The compounding weight ratio of the ingredient A to the ingredient B is desirable to be 0.01 to 100.0. The ingredient A is extracted from the leaves, stalks, roots and whole grass of parsley using an extraction solvent such as water. This skin cosmetic is useful as a cream, pack or the like.

Description

【発明の詳細な説明】DETAILED DESCRIPTION OF THE INVENTION

【0001】[0001]

【発明の属する技術分野】この発明は優れた保湿効果、
荒れ肌改善効果、老化防止効果、皮膚状態改善効果を持
つ皮膚化粧料に関するものである。
TECHNICAL FIELD The present invention provides an excellent moisturizing effect,
The present invention relates to a skin cosmetic having a rough skin improving effect, an anti-aging effect, and a skin condition improving effect.

【0002】[0002]

【従来の技術】紫外線などにより皮膚で発生する活性酸
素は皮膚の角質層及び表皮細胞、真皮細胞にダメージを
与え、老化の原因のひとつと考えられている。老化皮膚
とは角質層が乾燥して滑らかさがなく、荒れ肌や角質層
の剥離が見られる。また、表皮の細胞数は減少し、表皮
細胞の代謝が低下して皮膚のターンオーバー速度が遅く
なることが知られている。真皮においてはヒアルロン酸
の減少、コラーゲンやエラスチンなどの変性によりしわ
やたるみが認められる。従来の活性酸素消去作用を持つ
皮膚化粧料としてはパセリから抽出されるエキス(以下
パセリエキスという)を配合するものがあった(特開平
9−221410号公報)。一方、セラミドや糖セラミ
ドは角質層の細胞間脂質を整え、皮膚の水分蒸散を抑
え、皮膚のバリヤ機能を高める作用を有していることは
知られており、化粧料などに使用されている(特開昭6
1−260008号公報、特開昭62−56414号公
報)。
2. Description of the Related Art Active oxygen generated in the skin due to ultraviolet rays or the like damages the stratum corneum, epidermal cells, and dermal cells of the skin, and is considered to be one of the causes of aging. With aging skin, the stratum corneum is dry and not smooth, and rough skin and exfoliation of the stratum corneum are seen. It is also known that the number of cells in the epidermis decreases, the metabolism of epidermal cells decreases, and the turnover speed of the skin decreases. In the dermis, wrinkles and sagging are observed due to a decrease in hyaluronic acid and denaturation of collagen and elastin. As a conventional skin cosmetic having an active oxygen scavenging action, there has been one containing an extract extracted from parsley (hereinafter referred to as parsley extract) (Japanese Patent Application Laid-Open No. 9-22410). On the other hand, ceramide and sugar ceramide are known to have an effect of adjusting intercellular lipids in the stratum corneum, suppressing water evaporation of the skin, and enhancing the barrier function of the skin, and are used in cosmetics and the like. (JP 6
1-260008, JP-A-62-56414).

【0003】[0003]

【発明が解決しようとする課題】しかしながらパセリエ
キスを配合する化粧料では活性本質は皮膚に容易に浸透
し難く、単独ではその効果は十分であるとはいえない。
また近年ではオゾン層の破壊による紫外線量の増大が考
えられ、肌にとって有害であり、老化の原因のひとつと
して知られている活性酸素の対策やそれに伴ってダメー
ジを受けた肌細胞の賦活化、また環境の破壊や変化によ
る肌の乾燥、に対応する化粧品の開発が待望されてい
た。
However, in cosmetics containing parsley extract, the active essence hardly penetrates the skin easily, and the effect alone cannot be said to be sufficient.
In recent years, an increase in the amount of ultraviolet rays due to the destruction of the ozone layer is considered, which is harmful to the skin and measures against active oxygen, which is known as one of the causes of aging, and activation of damaged skin cells, Also, there has been a long-awaited demand for development of cosmetics that cope with drying of the skin due to destruction or change of the environment.

【0004】この発明は、こうした課題に鑑み、優れた
保湿効果、荒れ肌改善効果、老化防止効果、皮膚状態改
善効果を持つ皮膚化粧料を提供することにより上記課題
を解決しようとするものである。
[0004] In view of the above-mentioned problems, the present invention aims to solve the above-mentioned problems by providing a skin cosmetic having an excellent moisturizing effect, an effect of improving rough skin, an effect of preventing aging, and an effect of improving skin conditions.

【0005】[0005]

【課題を解決するための手段】そこでこの発明者らは鋭
意研究を重ねた結果、活性酸素消去作用を有するパセリ
から抽出されるエキスとセラミド及び糖セラミドから選
択される一種または二種を組み合わせて配合した場合、
それぞれを単独で配合した場合に比較して画期的に活性
酸素消去作用、細胞賦活作用、保湿作用が高まり、皮膚
内の活性酸素を消去し、日常の紫外線により受けた皮膚
細胞の損傷を回復させ、さらに皮膚内の表皮細胞に働き
かけてるターンオーバーを整え、皮膚のハリを保ち若々
しい肌を維持するという美肌効果を有することを見出
し、この発明を完成した。
The inventors of the present invention have conducted intensive studies and have found that the extract extracted from parsley having an active oxygen eliminating action is combined with one or two selected from ceramide and sugar ceramide. When combined
Efficiently enhances active oxygen scavenging, cell stimulating and moisturizing effects compared to when each is used alone, eliminating active oxygen in the skin and recovering skin cells damaged by daily ultraviolet rays Further, the present inventors have found that it has a beautiful skin effect of adjusting the turnover acting on the epidermal cells in the skin, keeping the skin firm and maintaining a youthful skin, and completed the present invention.

【0006】すなわち、この発明は、活性酸素消去効果
の優れた皮膚化粧料であり、パセリから抽出されるエキ
スとセラミド及び糖セラミドから選択される一種または
二種を組み合わせて配合する皮膚化粧料を提供するもの
である。
[0006] That is, the present invention is a skin cosmetic composition having an excellent effect of scavenging active oxygen, comprising an extract extracted from parsley and one or a combination of two or more selected from ceramide and sugar ceramide. To provide.

【0007】[0007]

【発明の実施の形態例】以下、この発明の構成を詳細に
説明する。この発明に用いられるパセリエキスはパセリ
(Petroseliumsativum)の葉、茎、
根及び全草から抽出されるエキスであり、抽出溶媒は特
に限定されないが、水、1,3−ブチレングリコール、
エタノール、グリセリン等の溶媒であり、単独もしくは
二種以上の混液により抽出されるエキスである。
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The structure of the present invention will be described below in detail. The parsley extract used in the present invention is parsley (Petroselium sativum) leaves, stems,
It is an extract extracted from roots and whole plants, and the extraction solvent is not particularly limited, but water, 1,3-butylene glycol,
It is a solvent such as ethanol and glycerin, and is an extract extracted alone or as a mixture of two or more.

【0008】この発明に用いられるセラミドは、例え
ば、牛、馬等の哺乳動物の組織より抽出されるものや、
米糠から得られる植物由来のもの、または化学合成によ
り得られるもの等がある。また、糖セラミドはグルコセ
ラミド、ガラクトシルセラミドなどであり、例えば、
牛、馬等の哺乳動物の組織より抽出されるものや、米糠
から得られる植物由来のもの、または化学合成により得
られるもの等がある。
Ceramides used in the present invention include those extracted from mammalian tissues such as cows and horses,
There are plants derived from rice bran and those obtained by chemical synthesis. The sugar ceramide is glucoceramide, galactosylceramide, etc., for example,
Examples include those extracted from the tissues of mammals such as cows and horses, those derived from plants obtained from rice bran, and those obtained by chemical synthesis.

【0009】この発明に用いられるパセリエキスの配合
量は皮膚化粧料の総量を基準として0.001〜10.
0重量%、より好ましくは0.01〜2.0重量%であ
り、用いられるセラミド及び糖セラミドの配合量は皮膚
化粧料の総量を基準として0.001〜5.0重量%、
より好ましくは0.01〜2.0重量%である。また、
パセリエキスとセラミド又は糖セラミドの配合比率とし
て、パセリエキス/セラミド又は糖セラミドが0.01
〜100.0が好ましい。この範囲でパセリエキスとセ
ラミドまたは糖セラミドを組み合わせて配合した皮膚化
粧料はこの発明の目的とする効果が得られる。
The amount of the parsley extract used in the present invention is 0.001 to 10.1 based on the total amount of the skin cosmetic.
0% by weight, more preferably 0.01 to 2.0% by weight, and the amount of ceramide and sugar ceramide used is 0.001 to 5.0% by weight based on the total amount of skin cosmetics.
More preferably, the content is 0.01 to 2.0% by weight. Also,
As a blending ratio of parsley extract and ceramide or sugar ceramide, parsley extract / ceramide or sugar ceramide is 0.01
-100.0 is preferred. Skin cosmetics containing a combination of parsley extract and ceramide or sugar ceramide within this range can achieve the effects intended by the present invention.

【0010】この発明の皮膚化粧料は、例えば洗顔料
類、ローション類、乳液類、クリーム類、パック類等に
適用することができる。尚、この発明の皮膚化粧料には
上記の他に色素、香料、防腐剤、界面活性剤、植物抽出
液、顔料、抗酸化剤等をこの発明の目的を達成する範囲
内で適宜配合することができる。
The skin cosmetic of the present invention can be applied to, for example, facial cleansers, lotions, emulsions, creams, packs and the like. The skin cosmetic of the present invention may contain, in addition to the above, dyes, fragrances, preservatives, surfactants, plant extracts, pigments, antioxidants, and the like, as long as the object of the present invention is achieved. Can be.

【0011】[0011]

【実施例】以下、実施例及び比較例に基づいてこの発明
を詳説する。また、この発明に使用した荒れ肌改善効果
試験、角質層のターンオーバー測定試験、官能テストは
下記の通りである。
The present invention will be described below in detail with reference to examples and comparative examples. The rough skin improvement effect test, the stratum corneum turnover measurement test, and the sensory test used in the present invention are as follows.

【0012】[荒れ肌改善効果試験]下脚部に荒れ肌を
有する中高年被験者10名を対象に4週間連続塗布し、
その効果を評価した。すなわち、被験者の左側下脚外側
試験部位に1日1回、約0.5gの試料を塗布し、試験
開始前および試験終了後の皮膚の状態を表1の判定基準
により判定した。右側下脚部は試料を塗布せずに対照と
した。
[Rough Skin Improving Effect Test] Apply to 10 middle-aged and elderly subjects having rough skin on lower legs for 4 weeks continuously.
The effect was evaluated. That is, about 0.5 g of a sample was applied once a day to the test site on the left lower leg outside of the test subject, and the skin condition before the start of the test and after the test was determined according to the criteria shown in Table 1. The right lower leg was used as a control without applying the sample.

【0013】[0013]

【表1】 [Table 1]

【0014】試験前後の試験部位と対照部位の判定結果
を比較し、皮膚乾燥度が2段階以上改善された場合(例
えば+→−、++→±)を有効、1段階改善された場合
をやや有効、変化がなかった場合を無効とした。試験結
果は有効、やや有効となった被験者の人数で示した。
By comparing the results of the judgment between the test site and the control site before and after the test, it is effective if the degree of dryness of the skin is improved by two or more steps (for example, + →-, ++ → ±). Valid, no change if not. The test results were indicated by the number of subjects who were effective or slightly effective.

【0015】[角質層のターンオーバー測定試験]蛍光
色素のダンシルクロライドを白色ワセリン中に5重量%
配合した軟膏を作り、被験者10名の前腕部の皮膚に2
4時間閉塞貼布し、角質層にダンシルクロライドを浸透
結合させた。その後同じ部位に1日2回(朝・夕)被験
試料を約0.2g塗布し、毎日1回暗所で紫外線ランプ
を用いて、ダンシルクロライドの蛍光を調べ、その蛍光
が消滅するまでの日数を皮膚角質層のターンオーバーと
した。
[Measurement test for turnover of stratum corneum] 5% by weight of fluorescent dye dansyl chloride was added to white petrolatum.
Make a blended ointment and apply it to the skin of the forearm of 10 subjects.
Closure was applied for 4 hours, and dansyl chloride was penetrated into the stratum corneum. Thereafter, about 0.2 g of the test sample was applied to the same site twice a day (morning and evening), and the fluorescence of dansyl chloride was examined once a day in a dark place using an ultraviolet lamp, and the number of days until the fluorescence disappeared Was used as the skin stratum corneum turnover.

【0016】[官能テスト(美肌効果試験)]荒れ肌、
小じわ、乾燥肌等を訴える女子被験者(35〜55才)
10人に試料を1日2回(朝・夕)連続4週間塗布して
4週間後の効果を評価した。試験結果は、皮膚の湿潤
性、平滑性、弾力性の各項目に対して、皮膚に潤いが生
じた、皮膚が滑らかになった、皮膚に張りが生じたと回
答した人数で示した。
[Sensory test (Beautiful skin effect test)]
Female subjects (35-55 years old) who complain of fine lines and dry skin
The samples were applied to 10 persons twice a day (morning / evening) for 4 consecutive weeks, and the effect after 4 weeks was evaluated. The test results were expressed by the number of people who answered that the skin was moistened, the skin became smooth, and the skin became taut for each item of skin wettability, smoothness, and elasticity.

【0017】[比較例1〜4及び実施例1〜12]表2
記載の組成の化粧液、比較例1〜4及び実施例1〜12
をそれぞれ常法に従って調製し、前記諸試験を実施し、
結果を表3に記載する。
Comparative Examples 1-4 and Examples 1-12 Table 2
Cosmetic liquid of the described composition, Comparative Examples 1 to 4 and Examples 1 to 12
Is prepared according to a conventional method, and the above-described tests are performed.
The results are shown in Table 3.

【0018】[0018]

【表2】 [Table 2]

【0019】[0019]

【表3】 [Table 3]

【0020】結果から基本となる比較例1の化粧液及び
比較例1の化粧液にパセリエキスとセラミドまたは糖セ
ラミドをそれぞれ単独に配合した化粧液、比較例2及び
比較例3及び比較例4に比べ、パセリエキスとセラミド
を組み合わせて配合した化粧液、実施例1、実施例2、
実施例3、実施例4、及び比較例1の化粧液にパセリエ
キスと糖セラミドを組み合わせて配合した化粧液、実施
例5、実施例6、実施例7、実施例8が荒れ肌改善効
果、ターンオーバー促進作用、美肌効果ともに高いこと
が示された。また、パセリエキスとセラミド及び糖セラ
ミドを組み合わせて配合した化粧液、実施例9、実施例
10、実施例11、実施例12に同様の効果が得られ
た。
Based on the results, the basic cosmetic liquid of Comparative Example 1 and the cosmetic liquid of Comparative Example 1 in which parsley extract and ceramide or sugar ceramide were individually added, Comparative Example 2, Comparative Example 3 and Comparative Example 4 were obtained. In comparison, a cosmetic liquid prepared by combining a parsley extract and a ceramide, Example 1, Example 2,
Cosmetic solutions prepared by combining parsley extract and sugar ceramide in combination with the cosmetic solutions of Examples 3, 4 and Comparative Example 1, and Examples 5, 6, 6, 7 and 8 show a rough skin improving effect, It was shown that both the over-promoting action and the beautiful skin effect were high. In addition, the same effects were obtained in the cosmetic liquids prepared by combining the parsley extract with ceramide and sugar ceramide, and in Examples 9, 10, 10, and 12.

【0021】[比較例5〜8及び実施例13〜24]表
4記載の組成のクリーム、比較例5〜8及び実施例13
〜24をそれぞれ常法に従って調製し、前記諸試験を実
施し、結果を表5に記載する。
[Comparative Examples 5 to 8 and Examples 13 to 24] Creams having the compositions shown in Table 4, Comparative Examples 5 to 8 and Example 13
To 24 were prepared according to a conventional method, and the above tests were carried out. The results are shown in Table 5.

【0022】[0022]

【表4】 [Table 4]

【0023】[0023]

【表5】 [Table 5]

【0024】結果から基本となる比較例5のクリーム及
び比較例5のクリームにパセリエキスとセラミド又は糖
セラミドをそれぞれ単独に配合したクリーム、比較例
6、比較例7、比較例8に比べ、パセリエキスとセラミ
ドを組み合わせて配合したクリーム、実施例13、実施
例14、実施例15、実施例16、及びパセリエキスと
糖セラミドを組み合わせて配合したクリーム、実施例1
7、実施例18、実施例19、実施例20が荒れ肌改善
効果、ターンオーバー促進作用、美肌効果ともに高いこ
とが示された。また、パセリエキスとセラミド及び糖セ
ラミドを組み合わせて配合したクリーム、実施例21、
実施例22、実施例23、実施例24に同様の効果が得
られた。
Based on the results, the cream of Comparative Example 5 and the cream of Comparative Example 5 each containing a parsley extract and ceramide or sugar ceramide alone were used. Example 13 and Example 14, Example 15, and Example 16 and cream containing a combination of extract and ceramide, and cream containing a combination of parsley extract and sugar ceramide, Example 1
7, Example 18, Example 19, and Example 20 showed that both the rough skin improving effect, the turnover promoting effect, and the beautiful skin effect were high. Further, a cream containing a combination of parsley extract, ceramide and sugar ceramide, Example 21,
The same effects as in Examples 22, 23 and 24 were obtained.

【0025】[0025]

【発明の効果】以上記載のごとく、この発明は、荒れ肌
改善効果、ターンオーバー促進作用、美肌効果の優れた
皮膚化粧料を提供することができる。
As described above, the present invention can provide a skin cosmetic which is excellent in rough skin improving effect, turnover promoting effect, and beautiful skin effect.

───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.7 識別記号 FI テーマコート゛(参考) A61P 17/16 A61K 31/00 617J Fターム(参考) 4C083 AA111 AA112 AB052 AC022 AC072 AC092 AC102 AC122 AC182 AC242 AC392 AC432 AC641 AC642 AD042 CC04 CC05 DD23 DD31 EE06 EE07 EE10 EE12 EE13 ──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. 7 Identification symbol FI Theme coat ゛ (Reference) A61P 17/16 A61K 31/00 617J F-term (Reference) 4C083 AA111 AA112 AB052 AC022 AC072 AC092 AC102 AC122 AC182 AC242 AC392 AC432 AC641 AC642 AD042 CC04 CC05 DD23 DD31 EE06 EE07 EE10 EE12 EE13

Claims (1)

【特許請求の範囲】[Claims] 【請求項1】 パセリから抽出されるエキスとセラミド
及び糖セラミドから選ばれる一種または二種を配合して
なることを特徴とする、皮膚化粧料。
1. A skin cosmetic comprising a mixture of an extract extracted from parsley and one or two selected from ceramide and sugar ceramide.
JP11074344A 1999-03-18 1999-03-18 Skin cosmetic Pending JP2000264833A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11074344A JP2000264833A (en) 1999-03-18 1999-03-18 Skin cosmetic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11074344A JP2000264833A (en) 1999-03-18 1999-03-18 Skin cosmetic

Publications (1)

Publication Number Publication Date
JP2000264833A true JP2000264833A (en) 2000-09-26

Family

ID=13544419

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11074344A Pending JP2000264833A (en) 1999-03-18 1999-03-18 Skin cosmetic

Country Status (1)

Country Link
JP (1) JP2000264833A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1454620A3 (en) * 2003-03-06 2005-04-13 Kao Corporation Skin aging-preventing or improving agent
JP2010100657A (en) * 2002-06-25 2010-05-06 Shiseido Co Ltd Antiaging preparation
JP2013189394A (en) * 2012-03-13 2013-09-26 Tsutsumi Planning:Kk Cosmetic material and cosmetic including the cosmetic material
KR101738974B1 (en) 2011-07-22 2017-05-23 (주)아모레퍼시픽 Skin external composition for anti-aging containing glucoceramide and 7,8,4'-trihydroxyisoflavone
KR20210109835A (en) * 2020-02-28 2021-09-07 (주)인터케어 Skin moisturizing and anti-wrinkle cosmetic composition containing a mixed extract using okra, molokhia and parsley

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010100657A (en) * 2002-06-25 2010-05-06 Shiseido Co Ltd Antiaging preparation
EP1454620A3 (en) * 2003-03-06 2005-04-13 Kao Corporation Skin aging-preventing or improving agent
KR101738974B1 (en) 2011-07-22 2017-05-23 (주)아모레퍼시픽 Skin external composition for anti-aging containing glucoceramide and 7,8,4'-trihydroxyisoflavone
JP2013189394A (en) * 2012-03-13 2013-09-26 Tsutsumi Planning:Kk Cosmetic material and cosmetic including the cosmetic material
KR20210109835A (en) * 2020-02-28 2021-09-07 (주)인터케어 Skin moisturizing and anti-wrinkle cosmetic composition containing a mixed extract using okra, molokhia and parsley
KR102580399B1 (en) * 2020-02-28 2023-09-20 주식회사 태영 Skin moisturizing and anti-wrinkle cosmetic composition containing a mixed extract using okra, molokhia and parsley

Similar Documents

Publication Publication Date Title
US20070134175A1 (en) Panthenol and natural organic extracts for reducing skin irritation
KR100767974B1 (en) A cosmetic composition for reducing the skin pore containing arctium lappa extracts and cold materials
FR2929511A1 (en) NEW ACTIVE PRINCIPLE STIMULATING THE PROLIFERATION AND / OR THE ACTIVITY OF FIBROBLASTS.
EP1837013B1 (en) Composition comprising hydroxyapatite and a calcium salt for reinforcing the barrier function of the skin and/or semi-mucus membranes.
CN110974767A (en) Composition for skin barrier regeneration repair and application thereof
JP2000229834A (en) Cosmetic
FR2902340A1 (en) COSMETIC COMPOSITION FOR TOPICAL USE COMPRISING WASABI
JP3908126B2 (en) Epidermal keratinization normalizing agent and skin external preparation containing the same
EP3616681A1 (en) Topical compositions comprising pichia anomala and retinol
JP3193542B2 (en) Anti-aging skin cosmetics
JP2000344655A (en) Skin cosmetic
FR3033699A1 (en) EXTRACT OF CHINA PEPPER, COMPOSITION COMPRISING SAID EXTRACT AND COSMETIC USE
WO2015147137A1 (en) Ceramide-formulated external agent composition
JPH0733637A (en) Skin cosmetic
JPH09315931A (en) Cosmetic material for skin
JP2000264833A (en) Skin cosmetic
KR100534185B1 (en) Moisturizing cosmetic compositions containing a beta-1,6-branched-beta-1,3-glucan
JPH10212225A (en) Wrinkle preventive
JP3939857B2 (en) Skin cosmetics
JP4216866B2 (en) Skin cosmetics
JP2001131031A (en) Composition for scalp and hair
JPH0429919A (en) Moisture-retaining cosmetic
JP3877914B2 (en) Skin cosmetics
JP3615001B2 (en) Skin cosmetics
JP2000264832A (en) Skin cosmetic