JP2000204079A5 - - Google Patents

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Publication number
JP2000204079A5
JP2000204079A5 JP1999053551A JP5355199A JP2000204079A5 JP 2000204079 A5 JP2000204079 A5 JP 2000204079A5 JP 1999053551 A JP1999053551 A JP 1999053551A JP 5355199 A JP5355199 A JP 5355199A JP 2000204079 A5 JP2000204079 A5 JP 2000204079A5
Authority
JP
Japan
Prior art keywords
alkyl
phenyl
pyridyl
cycloalkyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1999053551A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000204079A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2000204079A publication Critical patent/JP2000204079A/ja
Publication of JP2000204079A5 publication Critical patent/JP2000204079A5/ja
Withdrawn legal-status Critical Current

Links

JP11053551A 1999-01-13 1999-03-02 ジアリ―ルアミン Withdrawn JP2000204079A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11587399P 1999-01-13 1999-01-13
US115873 2005-04-27

Publications (2)

Publication Number Publication Date
JP2000204079A JP2000204079A (ja) 2000-07-25
JP2000204079A5 true JP2000204079A5 (enExample) 2006-04-27

Family

ID=22363895

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11053551A Withdrawn JP2000204079A (ja) 1999-01-13 1999-03-02 ジアリ―ルアミン

Country Status (2)

Country Link
JP (1) JP2000204079A (enExample)
ZA (1) ZA200105224B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID30439A (id) * 1999-01-13 2001-12-06 Warner Lambert Co Benzoheterosiklus dan penggunaannya sebagai penghambat mek
CA2532067C (en) * 2003-07-24 2010-12-21 Stephen Douglas Barrett N-methyle-substituted benzamidazoles
US7144907B2 (en) * 2003-09-03 2006-12-05 Array Biopharma Inc. Heterocyclic inhibitors of MEK and methods of use thereof
CA2660546A1 (en) * 2006-08-21 2008-02-28 Genentech, Inc. Aza-benzofuranyl compounds and methods of use
WO2008024724A1 (en) * 2006-08-21 2008-02-28 Genentech, Inc. Aza-benzothiophenyl compounds and methods of use
EP2370568B1 (en) 2008-12-10 2017-07-19 Dana-Farber Cancer Institute, Inc. Mek mutations conferring resistance to mek inhibitors
CA2789696C (en) 2010-02-25 2017-11-07 Dana-Farber Cancer Institute, Inc. Braf mutations conferring resistance to braf inhibitors
EP2545187B1 (en) 2010-03-09 2018-09-05 Dana-Farber Cancer Institute, Inc. Methods of diagnosing and treating cancer in patients having or developing resistance to a first cancer therapy
CN103204825B (zh) * 2012-01-17 2015-03-04 上海科州药物研发有限公司 作为蛋白激酶抑制剂的苯并噻唑化合物及其制备方法和用途
WO2013169858A1 (en) 2012-05-08 2013-11-14 The Broad Institute, Inc. Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5610398A (en) * 1997-02-28 1998-09-18 Warner-Lambert Company Method of treating or preventing septic shock by administering a mek inhibitor

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