JP2000191553A - Readily swallowable auxiliary composition and food composition and pharmaceutical composition using the same - Google Patents
Readily swallowable auxiliary composition and food composition and pharmaceutical composition using the sameInfo
- Publication number
- JP2000191553A JP2000191553A JP10372188A JP37218898A JP2000191553A JP 2000191553 A JP2000191553 A JP 2000191553A JP 10372188 A JP10372188 A JP 10372188A JP 37218898 A JP37218898 A JP 37218898A JP 2000191553 A JP2000191553 A JP 2000191553A
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- Japan
- Prior art keywords
- composition
- gum
- swallowing
- gel
- food
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Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Tea And Coffee (AREA)
- Jellies, Jams, And Syrups (AREA)
- Non-Alcoholic Beverages (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
【0001】[0001]
【発明の属する技術分野】本発明は、のどへの付着性が
軽減された易嚥下補助組成物ならびにこれを用いた食品
用組成物および医薬品用組成物に関し、詳しくは高齢者
や嚥下障害者が食品本来の香味や食感を楽しみ且つ安全
に嚥下でき、更に常温で長時間放置しても嚥下適性が優
れている易嚥下補助組成物並びにこれを用いた食品用組
成物及び医薬品用組成物に関する。[0001] The present invention relates to an easy swallowing composition having reduced adhesion to the throat, and a food composition and a pharmaceutical composition using the composition. The present invention relates to an easy-to-swallow auxiliary composition that can enjoy the original flavor and texture of food and can be swallowed safely, and has excellent swallowability even when left at room temperature for a long time, and a food composition and a pharmaceutical composition using the same. .
【0002】[0002]
【従来の技術】高齢者の人口増加に伴い、食物を飲み込
む動作に障害をきたす嚥下障害者の人口も増加する傾向
にある。加えて、脳血管障害、腫瘍等の疾病によって嚥
下障害を伴うことも多い。嚥下障害者にとっては、水の
ようにさらっとした食品は、誤嚥(誤って気管に食物が
はいること)しやすく、激しい咳込みや誤嚥性肺炎をお
こすことがしばしば認められている。一方、硬い固形物
では喉につかえ、窒息の危険性がある。その為に、従来
は、食品に増粘剤を添加して適当に粘度をつけたり、固
形物を細かく刻んできざみ食にすることが行われてき
た。しかし、これらの処理を施すと、食品本来の美味し
さや食事の楽しさと言った食欲を喚起する要因が除去さ
れてしまう場合もある。また、誤嚥による咳き込みや誤
嚥性肺炎の恐怖から、嚥下障害者は摂食を拒み低水分、
低栄養状態に陥りやすい。従って重度の嚥下障害者に
は、鼻からの経管栄養等で水分や栄養補給を行っている
が、このような現状は嚥下障害者の人間としての尊厳を
著しく低下させているといっても過言ではない。2. Description of the Related Art As the population of the elderly increases, the population of dysphagia people who have difficulty in swallowing food tends to increase. In addition, dysphagia often accompanies diseases such as cerebrovascular disorders and tumors. For people with dysphagia, dry foods, such as water, are apt to be aspirated (accidentally having food in the trachea), and are often found to cause severe coughing and aspiration pneumonia. On the other hand, hard solids can be stuck in the throat and risk choking. For this reason, conventionally, thickeners have been added to foods to provide appropriate viscosity, and solids have been finely chopped into chopped foods. However, when these treatments are performed, factors that stimulate appetite, such as the original taste of food and the pleasure of eating, may be removed. In addition, because of the danger of coughing and aspiration pneumonia caused by aspiration, people with dysphagia refuse to eat and have low moisture,
It is easy to fall into undernutrition. Therefore, for people with severe dysphagia, water and nutrients are supplied by tube feeding from the nose, etc., but even if such a current situation significantly reduces the dignity of people with dysphagia as humans It's not too much to say.
【0003】近年、このような嚥下障害者のQOL(生
活の質)を向上させようとする動きが社会的にも高ま
り、嚥下に適した食品物性とは何かを明らかにし、嚥下
障害者でも経口摂食が可能で食べる楽しみが得られ、か
つ摂食機能を向上させることができる食品を提供しよう
とする研究が活発になっている。それらの研究による
と、嚥下に適した食品物性とは(1)嚥下しやすい適度
な硬さや粘度を有すること、(2)食塊形成性(食品の
口の中でのまとまり易さ)が優れていること、および
(3)口腔内及び咽頭部内への付着が少ないこと、が挙
げられる。[0003] In recent years, the movement to improve the quality of life (QOL) of the dysphagic person has been increasing in society, and what is the physical properties of food suitable for swallowing has been clarified. Research for providing foods that can be eaten orally, provide pleasure to eat, and improve the eating function has been active. According to those studies, food properties suitable for swallowing are (1) having appropriate hardness and viscosity that are easy to swallow, and (2) excellent bolus formation (easiness of uniting food in the mouth). And (3) little adhesion to the oral cavity and pharynx.
【0004】先にも述べたように、従来より病院等で
は、誤嚥を防ぐ為に、水のようにさらっとして流動性の
ありすぎる液状食品には食品増粘剤を添加して粘凋性を
持たせてきた。このような食品増粘剤としては、冷水で
簡単に分散溶解しpHや塩類等の影響を受けにくいこと
から、澱粉、とりわけα化澱粉が好ましく使用されてき
た。しかしながら、澱粉系増粘剤は、汎用性の点では良
好であるが、上記したような嚥下に適した物性を食品に
付与するという面では不充分であった。すなわち澱粉系
増粘剤では、粘度の増加とともに付着性が著しく増加
するので、口腔内及び咽頭部内への付着残留による誤嚥
の危険性があったり、付着感によって飲み込み難さが増
大することなどが最近の研究で指摘されている。また
経時的に著しく粘度が増加することから、適切な粘度で
摂食者に提供することが困難であった。さらに嗜好面
でも好ましくない性質を有している。すなわち、食品の
外観色調を乳白濁化させ、且つ食品本来の香味・食感を
著しく変化させ劣化させることから、摂食者の食欲を低
下させる原因となることが指摘されている。[0004] As described above, in the past, in order to prevent aspiration, hospitals and the like have conventionally added a food thickener to liquid foods that are too fluid and liquid like water to make them viscous. I have. As such a food thickener, starch, particularly pregelatinized starch, has been preferably used because it is easily dispersed and dissolved in cold water and is not easily affected by pH, salts and the like. However, starch-based thickeners are good in versatility, but insufficient in imparting the above-mentioned physical properties suitable for swallowing to foods. In other words, with starch-based thickeners, adhesion increases significantly with increasing viscosity, so there is a risk of aspiration due to residual adhesion in the oral cavity and pharynx, and the difficulty in swallowing due to the feeling of adhesion increases. Has been pointed out in a recent study. Further, since the viscosity increases remarkably with time, it has been difficult to provide the feeder with an appropriate viscosity. Furthermore, it has unfavorable properties in terms of taste. That is, it has been pointed out that the appearance color tone of the food becomes milky turbid, and that the original flavor and texture of the food are significantly changed and deteriorated.
【0005】そこで、他の増粘多糖類やそれと澱粉との
併用が検討されており、例えば次のような嚥下補助剤に
関する技術が公開されている。 ・特開平5−38262号公報には、液状食品に直接添
加して食品に粘稠性を与える補助剤であって、タピオカ
澱粉と馬鈴薯澱粉、デキストリンからなるものが記載さ
れている。このものを用いると、上記の嗜好面での劣
化の問題については、従来のα化澱粉と比較するとかな
り改善されるが、まだ不十分である。また上記の付着
性と上記の粘度の経時的増加については、全く言及さ
れておらず、付着性及び粘度の経時的安定性は従来と同
程度に留まる。 ・特開平10−108633号公報は、液状食品に直接
添加して食品に適度な粘凋性を与える補助剤において、
溶解時の「ダマ」防止を訴求したものであって、グア−
ガム、キサンタンガム、デキストリンからなるものが記
載されている。このものは、上記の粘度の経時的安定
性、およびの嗜好面では澱粉系に比較して著しい改善
が認められるものの、の付着残留性及び付着感による
飲み込み難さについては全く考慮がなされてない。基本
的には従来の澱粉系の嚥下補助剤と同じ考え方に基づい
ている。即ち、粘性でのみ食品の流動性を抑制しようと
するものであって、このものでは流動性の抑制の程度と
付着性のバランスをとることは困難である。 ・特開平10−182478号公報には、蛋白質、糖
質、脂質、ビタミン及びミネラル類にゲル化剤として馬
鈴薯澱粉、トウモロコシ澱粉、モチトウモロコシ澱粉の
1種以上を併用した組成物が記載されている。ここでは
栄養面の充実に重点がおかれ、嚥下に適した物性につい
ては何ら考慮がなされていない。すなわち、従来の澱粉
系嚥下補助剤の域を出ておらず、上記〜の問題点の
解決には至っていない。[0005] Therefore, other thickening polysaccharides and their use in combination with starch have been studied, and for example, the following techniques relating to swallowing aids have been disclosed. JP-A-5-38262 describes an auxiliary agent which is added directly to a liquid food to impart viscosity to the food, and which comprises tapioca starch, potato starch, and dextrin. When this is used, the above-mentioned problem of deterioration in taste is considerably improved as compared with the conventional pregelatinized starch, but it is still insufficient. No mention is made of the above-mentioned adhesion and the above-mentioned increase in viscosity over time, and the stability over time of adhesion and viscosity remains the same as in the prior art. JP-A-10-108633 discloses an auxiliary agent which is added directly to a liquid food to give the food an appropriate viscosity.
Claims to prevent "lumps" during dissolution.
Gum, xanthan gum and dextrin are described. In this product, although the above-mentioned stability with time of the viscosity and the palatability are markedly improved as compared with the starch system, no consideration is given to the persistence of adhesion and difficulty in swallowing due to the feeling of adhesion. . Basically, it is based on the same concept as conventional starch-based swallowing aids. That is, it is intended to suppress the fluidity of food only by viscousness, and in this case, it is difficult to balance the degree of fluidity suppression and adhesion. JP-A-10-182478 describes a composition in which one or more of potato starch, corn starch, and waxy corn starch are used as a gelling agent in combination with proteins, carbohydrates, lipids, vitamins, and minerals. . The emphasis here is on nutritional enhancement, and no consideration is given to physical properties suitable for swallowing. That is, it does not fall outside the range of conventional starch-based swallowing aids, and has not solved the above-mentioned problems.
【0006】[0006]
【発明が解決しようとする課題】本発明は、上記事情に
鑑みなされたもので、従来の澱粉系補助剤が持つ上記の
欠点の全てを改善して上述した嚥下物性(1)〜
(3)を同時に満足する汎用性に優れた易嚥下補助組成
物ならびにこれを用いた食品用組成物及び医薬品用組成
物を提供することを目的とする。DISCLOSURE OF THE INVENTION The present invention has been made in view of the above circumstances, and all of the above-mentioned disadvantages of the conventional starch-based adjuvants have been improved to improve the above-mentioned swallowing properties (1) to (4).
It is an object of the present invention to provide an easy-to-swallow auxiliary composition which satisfies (3) at the same time and is excellent in versatility, and a food composition and a pharmaceutical composition using the composition.
【0007】[0007]
【課題を解決するための手段】前記課題はタラガムおよ
び/またはローカストビーンガムと、キサンタンガムと
を併用してなる易嚥下補助組成物によって解決できる。
タラガムおよび/またはローカストビーンガムと、キサ
ンタンガムに加えて、さらにサイリウムシードガムを配
合することが好ましい。本発明の易嚥下補助組成物は特
に、食する際のゲルの付着性が100g/m2以下であ
ることが好ましい。本発明の易嚥下補助組成物は、各種
の食品用素材や医薬品用素材と組み合わせて食品用組成
物および医薬品用組成物を提供するのに好適である。Means for Solving the Problems The above-mentioned problems can be solved by an easy-to-swallow composition comprising a combination of tara gum and / or locust bean gum and xanthan gum.
It is preferable to add psyllium seed gum in addition to tara gum and / or locust bean gum and xanthan gum. In particular, the composition for assisting swallowing of the present invention preferably has a gel adhesion of 100 g / m 2 or less when consumed. The swallowing aid composition of the present invention is suitable for providing a food composition and a pharmaceutical composition in combination with various food materials and pharmaceutical ingredients.
【0008】すなわち本発明者らは、上記課題を解決す
るために鋭意検討した結果、タラガム、ローカストビー
ンガムの中から選ばれる少なくとも1種以上とキサンタ
ンガムとを併用した場合に限って上記の欠点を全
て克服することができ、嚥下補助剤として最適な特性が
得られることを見い出した。すなわち、ガラクトマンナ
ンの中でもタラガムとローカストビーンガムは、キサン
タンガムとゲル構造を形成する事は良く知られていた
が、タラガムおよび/またはローカストビーンガムとキ
サンタンガムの配合比がある特定の範囲では、この形成
された構造が全体としてはゾル的性質を有しながら水の
ような液状食品の流動性を適度に抑制し、且つ経時的な
粘度の増加がなく、更に口腔内付着や付着感も著しく少
ないという嚥下物性として最適な特性を有することを見
いだした。またキサンタンガムとタラガムおよび/また
はローカストビーンガムとの混合物の食品への配合割合
によって、形成されるゲル状構造の硬さを自由に嚥下に
適した硬さに決定することができる。更に、このゲル状
構造物は非常に透明度が高いため、食品の外観を損なう
ことがほとんどなく、しかも非常に軽い食感の構造物で
あることから食品本来の食感を損なうことが澱粉系増粘
剤に比較して著しく少ない。なお、これに比べて上述の
特開平10ー108633号公報に記載されているグア
ーガムの場合は、キサンタンガムとのゲル状構造形成性
能は非常に弱く、むしろ粘性の著しい増加をもたらすこ
とが知られている。この点で本発明とは本質的に考え方
を異にするものである。That is, the present inventors have conducted intensive studies in order to solve the above-mentioned problems. As a result, the above-mentioned drawbacks have been found only when xanthan gum is used in combination with at least one or more selected from tara gum and locust bean gum. It has been found that they can all be overcome and obtain optimal properties as a swallowing aid. That is, among galactomannans, it is well known that tara gum and locust bean gum form a gel structure with xanthan gum, but in a specific range of the mixing ratio of tara gum and / or locust bean gum and xanthan gum, this formation is While the structure as a whole has a sol-like property as a whole, it moderately suppresses the flowability of liquid foods such as water, and there is no increase in viscosity over time, and furthermore, there is very little adhesion to the oral cavity and feeling of adhesion. It has been found that it has optimal properties as physical properties for swallowing. Further, the hardness of the gel-like structure formed can be freely determined to be suitable for swallowing by the mixing ratio of the mixture of xanthan gum and cod gum and / or locust bean gum to food. Further, since the gel-like structure has a very high transparency, it hardly impairs the appearance of the food, and since it is a structure having a very light texture, it is likely that the original texture of the food is impaired and the starch-based structure increases. Significantly less than a thickener. In contrast, in the case of guar gum described in the above-mentioned JP-A-10-108633, it is known that the performance of forming a gel-like structure with xanthan gum is very weak, and rather, it causes a remarkable increase in viscosity. I have. In this respect, the concept is essentially different from the present invention.
【0009】また、更に本発明者等は検討を重ね、上記
タラガムおよび/またはローカストビーンガムとキサン
タンガムとの混合物へサイリウムシードガムを微量配合
すると、飲み込み易さと食塊形成性が改善されることを
見いだした。サイリウムシードガムは糊感のない卵白様
の流動特性(塊を維持しようとする性質)を有してお
り、この特異な流動特性を持つサイリウムシードガムの
溶液が、上記のゲル状構造物が咀嚼されたときにその表
面を覆うことによって、飲み込み易さと食塊形成性の改
善が得られるものと考えられる。Further, the present inventors have further studied and found that when a small amount of psyllium seed gum is added to the above-mentioned mixture of cod and / or locust bean gum and xanthan gum, ease of swallowing and bolus formation are improved. I found it. The psyllium seed gum has an egg white-like flow property (property of maintaining a lump) without a feeling of glue, and the solution of the psyllium seed gum having this unique flow property is used to chew the above gel-like structure. It is thought that by covering the surface when it is done, it is easy to swallow and improved bolus formation.
【0010】[0010]
【発明の実施の形態】以下、本発明を詳しく説明する。
本発明で使用されるキサンタンガムとは、キサントモナ
ス・キャンペストリス(Xanthomonas ca
npestris)が産生する天然多糖類である。グル
コース、マンノース及びグルクロン酸(カリウム、ナト
リウム、カルシウムの混合塩)から構成され、主鎖はグ
ルコース、側鎖は二個のマンノースとグルクロン酸から
なるものが多い構造をしている。キサンタンガム製剤と
して種々のものが市販されているが、本発明ではいずれ
も使用可能である。DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below in detail.
Xanthan gum used in the present invention refers to Xanthomonas campestris (Xanthomonas ca).
npestris). It is composed of glucose, mannose, and glucuronic acid (a mixed salt of potassium, sodium, and calcium), and has a structure in which the main chain is composed of glucose and the side chain is composed mainly of two mannose and glucuronic acid. Although various xanthan gum preparations are commercially available, any of them can be used in the present invention.
【0011】次に本発明で用いられるタラガムとは、タ
ラ(Cesalpinia Spinosa)の種子の
胚乳部分を分離精製して粉末化した水溶性天然高分子多
糖類のことであり、ガラクトマンナンの一種である。ま
た本発明で用いられるローカストビーンガムは、タラガ
ムと同じくガラクトマンナンの仲間であるが、ローカス
トビーンガムは豆科の多年性常緑樹であるカロブ樹(C
arob tree)の種子の胚乳から得られる水溶性
天然多糖類である。ガラクトースとマンノースの比がタ
ラガムの場合は1:3、ローカストビーンガムの場合は
1:4である。タラガムおよびローカストビーンガムは
微粉化や精製等の処理を施されたものが市販されている
が、本発明ではいずれも使用可能である。Next, the cod gum used in the present invention is a water-soluble natural high molecular polysaccharide obtained by separating and purifying the endosperm portion of cod (Cesalpinia Spinosa) seeds and powdering the cod (Galactomannan). . The locust bean gum used in the present invention is a member of galactomannan like tara gum, but locust bean gum is a perennial evergreen tree of the legume family, carob tree (C
Arob tree) is a water-soluble natural polysaccharide obtained from endosperm of seeds. The ratio of galactose to mannose is 1: 3 for tara gum and 1: 4 for locust bean gum. Tara gum and locust bean gum are commercially available after being subjected to treatments such as pulverization and purification, but any of them can be used in the present invention.
【0012】本発明においてタラガム、ローカストビー
ンガムから選ばれる少なくとも1種とキサンタンガムの
配合比(タラガム、ローカストビーンガム/キサンタン
ガム)は、これらの混合物全体を100とした重量%で
25/75〜85/15、好ましくは、30/70〜7
5/25、より好ましくは40/60〜60/40であ
る。タラガムおよび/またはローカストビーンガムの割
合が25重量%より少なくても、また85重量%より多
くてもゲル形成能が弱く、それぞれ単独の粘性が目立つ
ようになり、咽頭部への付着性や粘着感による飲み込み
難さを軽減することが困難となる。更に経時的安定性を
確保することもできなくなる。In the present invention, the mixing ratio of at least one selected from tara gum and locust bean gum to xanthan gum (tara gum, locust bean gum / xanthan gum) is 25/75 to 85/85 / wt% based on the total weight of the mixture. 15, preferably 30/70 to 7
5/25, more preferably 40/60 to 60/40. If the proportion of cod gum and / or locust bean gum is less than 25% by weight or more than 85% by weight, the gel-forming ability is weak, and the viscosity of each becomes noticeable, and the adhesion and adhesion to the pharynx It becomes difficult to reduce the difficulty of swallowing due to feeling. Further, the stability over time cannot be ensured.
【0013】本発明で用いられるサイリウムシードガム
とはPlantago種(オオバコの一種、Plant
aginaceae)植物の中の、主にPlantag
oovata Forskal等の種子から採った天然
植物ガムのことである。サイリウムシードガムは種子の
外側を包む外皮ハスクの部分を用い、サイリウムハスク
(Psyllium Husk)と呼ばれインドではイ
サゴール(Isapgol、Isabgol)とも呼ば
れている。このサイリウムシードガムの成分中の非セル
ロース多糖類はキシランを主鎖として高度に分岐した構
造を持ち、側鎖は、アラビノース、キシロース、ガラク
チュロン酸、ラムノースからなっている。冷水でも十分
に膨潤増粘し、高い保水性を示す。また耐酸、耐塩性に
優れ、その粘性は長期間安定で、非ニュートン流動の卵
白様粘性を示すが糊のような食感はなくあっさりとして
いる。本発明では市販されているサイリウムシードガム
をいずれも使用可能である。本発明において、サイリウ
ムシードガムの配合割合は、タラガムおよび/またはロ
ーカストビーンガムとキサンタンガムとの混合物を10
0とした重量%で2〜20重量%、好ましくは3〜15
重量%、より好ましくは4〜10重量%である。2重量
%より少ないと、サイリウムシードガムの効果が発揮で
きず、20重量%より多い場合ではサイリウムシードガ
ムの流動特性が支配的になり、スプーンでとることが困
難となったり、サイリムシードガムの特異な香味が目立
つようになる。[0013] The psyllium seed gum used in the present invention is Plantago species (Plant plant, Plant
aginaceae) Plants, mainly Plantag
Ovata Forskal and other natural plant gums. The psyllium seed gum uses a portion of a husk husk that wraps the outside of the seed, and is called a psyllium husk (Psylium Husk), and is also called Isapogol (Isabgol) in India. The non-cellulose polysaccharide in the component of the psyllium seed gum has a highly branched structure with xylan as a main chain, and the side chain is composed of arabinose, xylose, galacturonic acid, and rhamnose. It swells and thickens sufficiently even in cold water and shows high water retention. Also, it has excellent acid and salt resistance, and its viscosity is stable for a long period of time. In the present invention, any commercially available psyllium seed gum can be used. In the present invention, the compounding ratio of the psyllium seed gum is such that the mixture of tara gum and / or locust bean gum and xanthan gum is 10%.
2 to 20% by weight, preferably 3 to 15%
%, More preferably 4 to 10% by weight. If it is less than 2% by weight, the effect of the psyllium seed gum cannot be exerted. If it is more than 20% by weight, the flow characteristics of the psyllium seed gum become dominant, making it difficult to take with a spoon, The unique flavor of this becomes noticeable.
【0014】本発明の易嚥下補助組成物は、タラガムお
よび/またはローカストビーンガムとキサンタンガムと
の混合物、またはこれにサイリウムシードガムをさらに
配合させたものを含有するもので、これを例えば水、
湯、飲料、スープ等の各種水溶液に溶解させることによ
ってゲル化し、嚥下適性に優れた性状を呈する。本発明
の易嚥下補助組成物の製造方法は、上記の必須成分を含
む配合剤を混合するものであれば特に制限されず、例え
ば各原料粉末をリボンミキサー、Vブレンダー等で所定
量混合する方法でもよい。The composition for assisting swallowing according to the present invention contains a mixture of cod and / or locust bean gum and xanthan gum, or a composition further mixed with psyllium seed gum.
It gels when dissolved in various aqueous solutions such as hot water, beverages, and soups, and exhibits excellent swallowability. The method for producing the swallowing assisting composition of the present invention is not particularly limited as long as the compounding agent containing the above essential components is mixed. For example, a method of mixing a predetermined amount of each raw material powder with a ribbon mixer, a V blender or the like. May be.
【0015】また本発明の易嚥下補助組成物は、次の測
定方法によって測定される付着性の値が100g/m2
以下であることが好ましい。本発明における付着性の測
定方法は、まず易嚥下補助組成物を脱イオン水に完全に
溶解させてゲルを調製し、このゲルをPYREX200ml
ビーカーに高さ55mmになるように入れる。次にStab
le Micro Systems社製テクスチャーアナライザー(TA
−XT2)を用い、直径19mm、長さ75mmの円柱
形プランジャーに脱イオン水で充分洗浄したニッピ株式
会社製コラーゲン膜(製品名:コラーゲンケーシング2
70)を装着し、これを上記ビーカー内に入れたゲルに
貫入速度2.0mm/sで、深度45mmまで貫入し、
その後同速度で上昇させる。その時のコラーゲン膜への
ゲルの付着量を求め、単位面積当たりの付着量の値を付
着性(単位;g/m2)とする。この方法によれば、ヒ
トの皮膚を構成する主な蛋白質であるコラーゲンからな
る膜と易嚥下補助組成物を含むゲルとの付着性が測定さ
れ、その値は易嚥下補助組成物を含むゲルを嚥下する際
の、のどへの付着性を表す指標となる。そしてこの値が
100g/m2以下であれば、のどへの付着性が比較的
小さく、嚥下し易い易嚥下補助組成物であると評価でき
る。尚、付着性測定に供されるゲルにおける易嚥下補助
組成物の濃度は任意の濃度とすることができ、用途等に
応じて設定された食する際の濃度で測定を行うことによ
って、食する際のゲルの付着性の値が得られる。The composition for assisting swallowing according to the present invention has an adhesiveness value of 100 g / m 2 measured by the following measuring method.
The following is preferred. The method for measuring the adhesiveness in the present invention is to first prepare a gel by completely dissolving the swallowing auxiliary composition in deionized water, and prepare the gel with 200 ml of PYREX.
Put into a beaker so that the height is 55 mm. Then Stab
le Micro Systems Texture Analyzer (TA
-XT2), a collagen membrane (product name: collagen casing 2) manufactured by Nippi Co., Ltd. which was sufficiently washed with deionized water in a cylindrical plunger having a diameter of 19 mm and a length of 75 mm.
70), and penetrated the gel placed in the beaker at a penetration speed of 2.0 mm / s to a depth of 45 mm,
Then it is raised at the same speed. The amount of the gel adhered to the collagen membrane at that time is determined, and the value of the amount of the adhered per unit area is defined as the adhesiveness (unit: g / m 2 ). According to this method, the adhesion between the membrane comprising collagen, which is the main protein constituting human skin, and the gel containing the swallowing assisting composition is measured, and the value is measured using the gel containing the swallowing assisting composition. When swallowing, it is an index indicating the adhesion to the throat. If this value is 100 g / m 2 or less, it can be evaluated that the composition has relatively low adhesion to the throat and is easy to swallow. In addition, the concentration of the swallowing auxiliary composition in the gel used for the adhesion measurement can be any concentration, and the measurement is performed at the concentration at the time of eating set according to the application, etc., thereby eating. The value of the gel adhesion is obtained.
【0016】本発明の易嚥下補助組成物は、例えば後述
する食品用組成物素材や医薬品用組成物素材と好適に組
み合わせて用いられ、嚥下適性に優れた食品用組成物ま
たは医薬品用組成物が得られる。食品用組成物及び医薬
品用組成物中での易嚥下補助組成物の配合割合は特に規
定されないが、水、湯、飲料、スープ等の水溶液に溶解
させる場合には、易嚥下補助組成物(ゲル化剤)濃度と
して0.1〜10.0重量%とするのが好ましい。0.
1重量%未満では、組合せによっては食品の流動性を充
分に抑制できない場合があり、10.0重量%を越える
と粘度やゲル強度が強すぎて嚥下適性が著しく劣るおそ
れがある。またより好ましくは0.3〜6.0重量%で
あり、さらに好ましくは0.5〜2.0重量%である。The composition for assisting swallowing of the present invention is preferably used in combination with, for example, a composition material for food or a composition material for pharmaceuticals described below. can get. The mixing ratio of the swallowing auxiliary composition in the food composition and the pharmaceutical composition is not particularly limited. However, when the composition is dissolved in an aqueous solution such as water, hot water, a beverage, or a soup, the composition is easily swallowed. (Agent) The concentration is preferably 0.1 to 10.0% by weight. 0.
If the amount is less than 1% by weight, the fluidity of the food may not be sufficiently suppressed depending on the combination. If the amount is more than 10.0% by weight, the viscosity and gel strength may be too high, and the swallowability may be significantly deteriorated. Further, the content is more preferably 0.3 to 6.0% by weight, and still more preferably 0.5 to 2.0% by weight.
【0017】本発明で用いられる食品用組成物素材とし
ては、例えば糖質(ぶどう糖、果糖、砂糖、麦芽糖、乳
糖、トレハロース、粉末水飴、エリスリトール、キシリ
トール、ソルビトール、還元麦芽糖、還元乳糖、還元水
飴粉末、キシロオリゴ糖、ポリデキストロース等を1種
単独でまたは適宜混合)、酸味料(クエン酸、リンゴ
酸、乳酸、コハク酸、酒石酸、アスコルビン酸、クエン
酸塩、リンゴ酸塩、乳酸塩、コハク酸塩、酒石酸塩、ア
スコルビン酸塩等を1種単独でまたは適宜混合)、香
料、着色料、ビタミン類(ビタミンA、ビタミンB1、
ビタミンB2、ナイアシン、ビタミンB6、ビタミンB
12、ニコチン酸、ビタミンD群、ビタミンE、ビタミ
ンK、ビオチン、パントテン酸、葉酸等を1種単独でま
たは適宜混合)、ミネラル類(ナトリウム、カリウム、
カルシウム、マグネシウム、鉄、亜鉛、銅、リン、マン
ガン、ヨウ素等を含む塩類や食品素材を1種単独でまた
は適宜混合)、各種蛋白質(大豆蛋白、乳蛋白、小麦蛋
白、卵蛋白、魚肉蛋白、牛肉蛋白、豚肉蛋白、鶏肉蛋白
等を1種単独でまたは適宜混合)、各種油脂類(動植物
油脂、中鎖脂肪酸トリグリセライド等を1種単独でまた
は適宜混合)、甘味料(アスパルテーム、ステビア等を
1種単独でまたは適宜混合)、食物繊維(セルロース、
ガラクトマンナン、グアガム分解物、難消化性デキスト
リン、コーンファイバー、ペクチン等を1種単独でまた
は適宜混合)、各種果汁類(リンゴ、オレンジ、みか
ん、ぶどう、なし、もも、メロン、バナナ、パイン、す
いか等を1種単独でまたは適宜混合)、フレーバー粉末
(コーヒー粉末、抹茶粉末、煎茶粉末、ココア粉末等を
1種単独でまたは適宜混合)、安定化剤(グリセリン脂
肪酸エステル、ショ糖脂肪酸エステル、ソルビタン脂肪
酸エステル、プロピレングリコール脂肪酸エステル、リ
ン脂質、キラヤサポニン、大豆サポニン等を1種単独で
または適宜混合)、調味料(塩、味噌、醤油、酒類、み
りん、動植物エキス等を1種単独でまたは適宜混合)、
スパイス類(ホワイトペパー、ブラックペパー、バジ
ル、レッドペパー、わさび、からし、しょうが、ガーリ
ック、シナモン、クローブ等を1種単独でまたは適宜混
合)、野菜類(トマト、セロリ、オニオン等を1種単独
でまたは適宜混合)、種実類(アーモンド、ピーナッ
ツ、クルミ等を1種単独でまたは適宜混合)、山芋類ま
たはその粘質物質等が挙げられる。また医薬品用組成物
素材としては、例えば上記の各種ビタミン類や、アセト
アミノフェン、イブプロフェン、ケトプロフェン、メフ
ェナム酸等が挙げられる。Examples of the food composition material used in the present invention include sugars (glucose, fructose, sugar, maltose, lactose, trehalose, powdered syrup, erythritol, xylitol, sorbitol, reduced maltose, reduced lactose, reduced syrup) , Xylo-oligosaccharides, polydextroses, etc. alone or as appropriate), acidulants (citric acid, malic acid, lactic acid, succinic acid, tartaric acid, ascorbic acid, citrate, malate, lactate, succinate) , Tartrate, ascorbate, etc. alone or as appropriate), flavors, colorings, vitamins (vitamin A, vitamin B1,
Vitamin B2, niacin, vitamin B6, vitamin B
12, nicotinic acid, vitamin D group, vitamin E, vitamin K, biotin, pantothenic acid, folic acid, etc., alone or as appropriate, and minerals (sodium, potassium,
Salts and food materials containing calcium, magnesium, iron, zinc, copper, phosphorus, manganese, iodine, etc., singly or in an appropriate mixture, and various proteins (soy protein, milk protein, wheat protein, egg protein, fish protein, Beef protein, pork protein, chicken protein, etc., singly or as appropriate), various fats and oils (animal and vegetable oils, medium-chain fatty acid triglyceride, etc., singly or as appropriate), sweeteners (aspartame, stevia, etc.) Seeds alone or as appropriate), dietary fiber (cellulose,
Galactomannan, guar gum decomposed product, indigestible dextrin, corn fiber, pectin, etc., alone or appropriately mixed), various juices (apple, orange, tangerine, grape, none, peach, melon, banana, pine, Watermelon or the like alone or appropriately mixed), flavor powder (coffee powder, matcha powder, sencha powder, cocoa powder, etc. alone or appropriately mixed), stabilizer (glycerin fatty acid ester, sucrose fatty acid ester, Sorbitan fatty acid ester, propylene glycol fatty acid ester, phospholipid, quillain saponin, soybean saponin, etc., alone or as appropriate), seasoning (salt, miso, soy sauce, liquor, mirin, animal and plant extracts, etc. alone or Mix appropriately),
Spices (white pepper, black pepper, basil, red pepper, wasabi, mustard, ginger, garlic, cinnamon, clove, etc. alone or as appropriate) and vegetables (tomato, celery, onion, etc.) Or appropriately mixed), seeds and nuts (almonds, peanuts, walnuts, etc., singly or appropriately mixed), yams or a sticky substance thereof. Examples of the composition material for pharmaceuticals include the above-mentioned various vitamins, acetaminophen, ibuprofen, ketoprofen, mefenamic acid and the like.
【0018】なお、本発明における易嚥下補助組成物及
びそれを用いた食品組成物並びに医薬品組成物は、嚥下
が良好でかつ常温で長時間放置しても嚥下適性に優れる
ことを特徴とするものであって、他の成分、原料の使用
について制限されるものではない。例えば本発明で得ら
れる好ましい特性に悪影響を与えない範囲で、他のガム
類などを共存させてもよく、例えば、グアガム、ジェラ
ンガム、カラギーナン、ゼラチン、寒天、タピオカ澱
粉、馬鈴薯澱粉などを適宜配合することも可能である。The composition for assisting swallowing according to the present invention and the food and pharmaceutical compositions using the same are characterized by good swallowing and excellent swallowability even when left at room temperature for a long time. However, the use of other components and raw materials is not limited. For example, other gums and the like may be allowed to coexist within a range that does not adversely affect the preferable properties obtained in the present invention. For example, guar gum, gellan gum, carrageenan, gelatin, agar, tapioca starch, potato starch and the like are appropriately blended. It is also possible.
【0019】本発明の易嚥下補助組成物は、タラガムお
よび/またはローカストビーンガムと、キサンタンガム
とを必須成分として含有するものであり、液状食品の流
動性を適度に抑制するものであるので、高齢者や嚥下障
害者が安全に嚥下できるとともに、食品に添加しても食
品の外観や食感をほとんど損なわないので嗜好面での劣
化がほとんどないうえ、経時的な粘度の増加がなく、さ
らに付着性も著しく少ないという優れた嚥下適性が得ら
れるものである。また、さらにサイリウムシードガムを
併用すれば、飲み込み易さと食塊形成性を改善すること
ができる。したがって本発明の易嚥下補助組成物を用い
た食品用組成物および医薬品用組成物は、例えば病院や
高齢者を対象とした各種施設における給食や医薬品に好
適であるほか、嚥下が未熟な乳児の離乳食や医薬品、あ
るいはスプーンですくって口へ運ぶ動作が未発達の幼児
のための食品や医薬品としても好適である。The composition for assisting swallowing according to the present invention contains cod gum and / or locust bean gum and xanthan gum as essential components, and moderately suppresses the fluidity of a liquid food. Can be swallowed safely by the elderly and those with dysphagia, and when added to food, there is almost no deterioration in the appearance and texture of the food, so there is almost no deterioration in taste, and there is no increase in viscosity over time and further adhesion It has excellent swallowability, which is also extremely low. In addition, when psyllium seed gum is further used, swallowability and bolus formation can be improved. Therefore, the food composition and the pharmaceutical composition using the easy swallowing composition of the present invention are suitable for feeding and medicine in hospitals and various facilities for the elderly, and for swallowing immature infants. It is also suitable as baby food or medicine, or as food or medicine for infants who have yet to develop a spoon and carry it to the mouth.
【0020】[0020]
【実施例】以下、実施例及び比較例を示して本発明を具
体的に説明するが、本発明は下記実施例に制限されるも
のではない。尚、以下の例において%はすべて重量%を
意味する。 (実施例1〜11、比較例1〜10)下記表1および表
2に示した配合割合で調製した組成物を表1および表2
に示す濃度(ゲル化剤濃度)で用い、後述のようにして
ゲルを調製した。また得られたゲルについて官能試験お
よび付着性の測定を行って嚥下適性を評価した。その結
果を表に合わせて示す。EXAMPLES The present invention will be described in detail below with reference to examples and comparative examples, but the present invention is not limited to the following examples. In addition, in the following examples, all% means weight%. (Examples 1 to 11, Comparative Examples 1 to 10) Compositions prepared at the mixing ratios shown in Tables 1 and 2 below were prepared as shown in Tables 1 and 2.
(Gelling agent concentration), and a gel was prepared as described below. In addition, the obtained gel was subjected to a sensory test and adhesion measurement to evaluate swallowability. The results are shown in the table.
【0021】〈ゲルの調製〉表1および2に示す配合割
合の組成物(ゲル化剤)に粉糖3.8gを加えて粉体混
合し(全体で5gとなる)、これを5℃の脱イオン水9
5ccに徐々に加えて分散し、完全に溶解させた後、5
℃で一晩放置した。但し、ゲル化剤としてトロミアッ
プ、スルーソフトを用いる場合(比較例6,7)は、粉
糖を加えず、ゲル化剤3gに脱イオン水97ccを加え
てゲルを調製した。 〈官能試験〉調製したゲルの外観(透明感)・香味(異
味異臭)・粘つき感・飲み込み易さについては、専門パ
ネル3名で評価した。また粘つき感と飲み込み易さにつ
いては、上記のようにして調製したゲルを5℃に保持
し、調製してから10分後および5時間後にそれぞれ官
能試験を行った。 これらの官能試験の評価結果は◎:非常に良好、○:良
好、△:やや悪い、×:悪い で示した。 〈付着性〉ゲルの付着性は、上述したコラーゲン膜を用
いた測定方法により測定した。<Preparation of Gel> 3.8 g of powdered sugar was added to the compositions (gelling agents) shown in Tables 1 and 2 and mixed with powder (total 5 g). Deionized water 9
Add 5 cc gradually, disperse, and completely dissolve.
Left at 0 ° C. overnight. However, when using tolomi up and through soft as gelling agents (Comparative Examples 6 and 7), gel was prepared by adding 97 cc of deionized water to 3 g of gelling agent without adding powdered sugar. <Sensory Test> The appearance (transparency), flavor (unpleasant odor), stickiness, and ease of swallowing of the prepared gel were evaluated by three specialized panels. Regarding stickiness and ease of swallowing, the gel prepared as described above was kept at 5 ° C., and a sensory test was performed 10 minutes and 5 hours after preparation. The evaluation results of these sensory tests are shown as ◎: very good, :: good, Δ: slightly bad, ×: bad. <Adhesiveness> The adhesiveness of the gel was measured by the above-described measurement method using a collagen membrane.
【0022】[0022]
【表1】 [Table 1]
【0023】[0023]
【表2】 [Table 2]
【0024】表1および表2において (*1):大日本製薬株式会社製エコーガムRD (*2):三栄源エフエフ・アイ株式会社製ビストップ
D−1321 (*3):MRCポリサッカライド株式会社製精製タラ
ガム (*4):三晶株式会社MEYPRODYN200 (*5):大日本製薬株式会社ヘルシーガム (*6):日清サインス株式会社製トロミアップ(デキ
ストリン) (*7):キッセイ薬品工業株式会社製スルーソフトS
(デンプン)である。In Tables 1 and 2, (* 1): Echogum RD manufactured by Dainippon Pharmaceutical Co., Ltd. (* 2): Vistop D-1321 manufactured by Saneigen FFI Co., Ltd. (* 3): MRC Polysaccharide Co., Ltd. Purified cod gum (* 4): MEYPRODYN200 (* 5): Healthy gum (Dainippon Pharmaceutical Co., Ltd.) (* 6): Tolomiup (dextrin) manufactured by Nisshin Signs Co., Ltd. (* 7): Kissei Pharmaceutical Co., Ltd. Company-made through soft S
(Starch).
【0025】(実施例12,13)表3に示す配合割合
で各原料を均一に混合して易嚥下補助組成物を得た。表
3において、SLENDID 200(*8)はコペンハーゲンペ
クチンファクトリー社製脂肪代替物(ペクチン)であ
る。これ以外の配合剤は上記表1,2で使用したものと
同様のものを用いた。実施例12は、ゲルのなめらか
さ、外観的な均一性を訴求したもので、実施例13は、
食感的な「重さ」をSLENDIDを使用して調節した
ものである。また得られた易嚥下補助組成物(ゲル化
剤)5gを冷水95g(5℃)に入れてよくかき混ぜ、
上記実施例1と同様の方法で嚥下適性の評価を行った。
その結果を表3に併記した。ただし粘つき感と飲み込み
易さについては、調製したゲルを5℃に保持し、調製し
てから5時間後の評価結果のみを示した。(Examples 12 and 13) Each raw material was uniformly mixed at the compounding ratio shown in Table 3 to obtain an easy swallowing auxiliary composition. In Table 3, SLENDID 200 (* 8) is a fat substitute (pectin) manufactured by Copenhagen Pectin Factory. The other compounding agents used were the same as those used in Tables 1 and 2 above. Example 12 was directed to the smoothness and uniformity of appearance of the gel.
The texture "weight" is adjusted using SLENDID. In addition, 5 g of the obtained easy-to-swallow auxiliary composition (gelling agent) was placed in 95 g of cold water (5 ° C.) and stirred well.
Evaluation of swallowing suitability was performed in the same manner as in Example 1 above.
The results are shown in Table 3. However, with regard to stickiness and ease of swallowing, only the evaluation results 5 hours after the prepared gel was kept at 5 ° C. and prepared.
【0026】[0026]
【表3】 [Table 3]
【0027】(実施例14:嚥下困難者用グレープ風味
ゲル状飲料の素組成物)下記表4に示した成分原料を均
一に混合してグレープ風味ゲル状飲料の素を調製した。
得られた組成物17gを冷水83gに溶解させたゲル状
飲料を5℃に5時間保持した後に、上記実施例1と同様
にして嚥下適性を評価した。その結果を表に併記する。
本実施例で得られたゲル状飲料は長時間経過しても良好
な嚥下適性を有することが認められた。(Example 14: Elemental composition of grape-flavored gel drink for people with dysphagia) The ingredients shown in Table 4 below were uniformly mixed to prepare an element of a grape-flavored gel drink.
After maintaining a gel drink in which 17 g of the obtained composition was dissolved in 83 g of cold water at 5 ° C. for 5 hours, the swallowing suitability was evaluated in the same manner as in Example 1 above. The results are shown in the table.
It was confirmed that the gel beverage obtained in this example had good swallowability even after a long period of time.
【0028】[0028]
【表4】 [Table 4]
【0029】(実施例15:嚥下困難者用ゲル状煎茶飲
料の素組成物)下記表5に示した各粉末原料を均一に混
合してゲル状煎茶飲料の素組成物を調製した。得られた
組成物17.4gに冷水82.6gを入れてよくかき混
ぜたゲル状煎茶飲料を5℃に5時間保持した後、上記実
施例1と同様にして嚥下適性を評価した。その結果を表
に併記する。本実施例で得られたゲル状煎茶飲料は長時
間経過しても良好な嚥下適性を有することが認められ
た。(Example 15: Elementary composition of gel-type sencha beverage for people with dysphagia) The powdery ingredients shown in Table 5 below were uniformly mixed to prepare an elementary composition of a gel-type sencha beverage. A gel sencha beverage obtained by adding 82.6 g of cold water to 17.4 g of the obtained composition and stirring well was kept at 5 ° C. for 5 hours, and the swallowing suitability was evaluated in the same manner as in Example 1 above. The results are shown in the table. It was confirmed that the gel-like green tea beverage obtained in this example had good swallowability even after a long period of time.
【0030】[0030]
【表5】 [Table 5]
【0031】(実施例16:嚥下困難者用ゲル状アイソ
トニック飲料の素組成物)下記表6に示した各粉末原料
を均一に混合してゲル状アイソトニック飲料の素組成物
を調製した。得られた組成物8.036gに冷水91.
964gを入れてよくかき混ぜたゲル状アイソトニック
飲料を、上記実施例1と同様にして嚥下適性の評価を行
った。結果を表に併記する。本実施例のゲル状アイソト
ニック飲料は長時間経過しても良好な嚥下適性を有する
ことが認められた。(Example 16: Elementary composition of gel-like isotonic beverage for people with dysphagia) The powdery ingredients shown in Table 6 below were uniformly mixed to prepare an elementary composition of a gel-like isotonic beverage. Add 8.036 g of the obtained composition to 91.0 g of cold water.
The gel-like isotonic beverage containing 964 g and well mixed was evaluated for swallowing suitability in the same manner as in Example 1 above. The results are shown in the table. It was confirmed that the gel isotonic beverage of this example had good swallowability even after a long period of time.
【0032】[0032]
【表6】 [Table 6]
【0033】(実施例17:嚥下困難者用ゲル状栄養補
給飲料の素組成物)下記表7に示した各粉末原料を均一
に混合してゲル状栄養補給飲料の素組成物を調製した。
得られた組成物28.4gに冷水71.6gを入れよく
かき混ぜて得られたゲル状栄養補給飲料について、上記
実施例1と同様にして嚥下適性の評価を行った。結果を
表に併記する。本実施例のゲル状栄養補給飲料は長時間
経過しても良好な嚥下適性を有することが認められた。Example 17 Elementary Composition of Gel-Type Nutritional Supplement Drink for Difficult Swallowing Each elemental powder shown in Table 7 below was uniformly mixed to prepare an elemental composition of a gel-type nutritional supplement drink.
In the same manner as in Example 1, the evaluation of swallowing suitability was performed for a gel-type nutritional supplement drink obtained by adding 71.6 g of cold water to 28.4 g of the obtained composition and stirring well. The results are shown in the table. It was confirmed that the gel-type nutritional supplement beverage of this example had good swallowability even after a long period of time.
【0034】[0034]
【表7】 [Table 7]
【0035】(実施例18:嚥下困難者用ゲル状ビタミ
ン強化飲料の素組成物)下記表8に示した各粉末原料を
均一に混合してゲル状ビタミン強化飲料の素組成物を調
製した。得られた組成物19gに冷水81gを入れてよ
くかき混ぜたゲル状ビタミン強化飲料について実施例1
と同様にして嚥下適性の評価を行った。結果を表に併記
する。本実施例のゲル状ビタミン強化飲料は長時間経過
しても良好な嚥下適性を有することが認められた。Example 18 Elementary Composition of Gelled Vitamin-Enhanced Beverage for Persons with Difficulty Swallowing Each elemental powder shown in Table 8 below was uniformly mixed to prepare an elementary composition of a gel-type vitamin-enriched beverage. Example 1 Regarding a gel-form vitamin-enriched beverage obtained by adding 81 g of cold water to 19 g of the obtained composition and stirring well.
Evaluation of swallowing suitability was performed in the same manner as described above. The results are shown in the table. It was confirmed that the gel-form vitamin-enriched beverage of this example had good swallowability even after a long period of time.
【0036】[0036]
【表8】 [Table 8]
【0037】(実施例19:嚥下困難者用ゲル状アセト
アミノフェン含有飲料の素組成物)下記表9に示した各
粉末原料を均一に混合してゲル状アセトアミノフェン含
有飲料の素組成物を調製した。得られた組成物12.2
gに冷水87.8gを入れよくかき混ぜたゲル状アセト
アミノフェン含有飲料について、上記実施例1と同様に
して嚥下適性の評価を行った。結果を表に併記する。本
実施例のゲル状アセトアミノフェン含有飲料は長時間経
過しても良好な嚥下適性を有することが認められた。Example 19 Elementary Composition of Gel-Type Acetaminophen-Containing Beverage for Persons with Difficult Swallowing Elementary Composition of Gel-Type Acetaminophen-Containing Beverage by Uniformly Mixing Powdered Materials shown in Table 9 below Was prepared. The resulting composition 12.2
The swallowing suitability was evaluated in the same manner as in Example 1 above, for a gel-containing acetaminophen-containing beverage in which 87.8 g of cold water was added and stirred well. The results are shown in the table. It was confirmed that the gelled acetaminophen-containing beverage of this example had good swallowability even after a long period of time.
【0038】[0038]
【表9】 [Table 9]
【0039】(実施例20:オブラート代替え易嚥下ゲ
ル状製剤組成物)下記表10に示した各粉末原料を均一
に混合してオブラート代替え易嚥下ゲル状製剤組成物を
調製した。この組成物は、冷水や温湯等に溶かして非常
に柔らかいゲル状物としたところに風邪薬等の散剤を分
散することによって、高齢者や幼児等が飲み込みやすく
したものである。また得られた組成物20gを冷水80
g(5℃)に入れてかきまぜたゲル状物について上記実
施例1と同様にして嚥下適性の評価を行った。本実施例
のオブラート代替え易嚥下ゲル物は長時間経過しても良
好な嚥下適性を有することが認められた。(Example 20: Gel-form formulation for swallow-replacement easy swallowing) Each raw material shown in Table 10 below was uniformly mixed to prepare a gel-form formulation for swallow-replacement easy swallowing. This composition is intended to be easily swallowed by elderly people, infants and the like by dispersing a powder such as a cold medicine in a very soft gel when dissolved in cold water or hot water. Also, 20 g of the obtained composition was added to 80 ml of cold water.
g (5 ° C.) and stirred to evaluate the swallowing suitability in the same manner as in Example 1 above. It was confirmed that the swallow-replaceable easy-to-swallow gel product of this example had good swallowability even after a long period of time.
【0040】[0040]
【表10】 [Table 10]
【0041】[0041]
【発明の効果】以上説明したように、本発明によれば、
高齢者や嚥下障害者が、安全に且つ食品本来の美味し
さを楽しみながら嚥下でき、常温で長時間放置しても嚥
下に適した物性を維持できる易嚥下補助組成物が得られ
る。この易嚥下補助組成物は食品用組成物並びに医薬品
用組成物などの用途に幅広く応用できるものである。As described above, according to the present invention,
An easy swallowing auxiliary composition can be obtained that can be swallowed safely by the elderly and persons with dysphagia while enjoying the original taste of food, and maintain physical properties suitable for swallowing even when left at room temperature for a long time. The composition for assisting swallowing can be widely applied to applications such as food compositions and pharmaceutical compositions.
フロントページの続き (51)Int.Cl.7 識別記号 FI テーマコート゛(参考) A61K 9/00 A23L 2/38 B // A23F 3/30 A61K 31/165 A23L 2/38 A23L 1/04 A61K 31/165 2/00 E F (72)発明者 尾杉 孝夫 東京都墨田区本所一丁目3番7号 ライオ ン株式会社内 Fターム(参考) 4B017 LC02 LC03 LE06 LK06 LK08 LK10 LK12 LK13 LK16 LK18 LK20 LL01 4B027 FB13 FC10 FE02 FE05 FK04 FP85 4B041 LC10 LD10 LE10 LH01 LH16 LK07 LK11 LK37 LK39 4C076 AA11 AA99 BB01 CC01 CC24 CC40 DD43 DD67 EE58 FF36 FF52 FF68 FF70 4C206 AA01 AA02 GA31 MA03 MA05 MA36 MA72 NA03 NA09 NA10 NA20 ZA07 ZA08 Continued on the front page (51) Int.Cl. 7 Identification symbol FI Theme coat II (Reference) A61K 9/00 A23L 2/38 B // A23F 3/30 A61K 31/165 A23L 2/38 A23L 1/04 A61K 31 / 165 2/00 EF (72) Inventor Takao Osugi 1-37 Honjo, Sumida-ku, Tokyo F-term in Lion Corporation (reference) 4B017 LC02 LC03 LE06 LK06 LK08 LK10 LK12 LK13 LK16 LK18 LK20 LL01 4B027 FB13 FC10 FE02 FE05 FK04 FP85 4B041 LC10 LD10 LE10 LH01 LH16 LK07 LK11 LK37 LK39 4C076 AA11 AA99 BB01 CC01 CC24 CC40 DD43 DD67 EE58 FF36 FF52 FF68 FF70 4C206 AA01 AA03 NA03 MA05 MA05
Claims (5)
ンガムと、キサンタンガムとを併用してなることを特徴
とする易嚥下補助組成物。1. A swallowing auxiliary composition comprising a combination of tara gum and / or locust bean gum and xanthan gum.
なることを特徴とする請求項1記載の易嚥下補助組成
物。2. The composition according to claim 1, further comprising psyllium seed gum.
嚥下補助組成物において、食する際のゲルの付着性が1
00g/m2以下であることを特徴とする易嚥下補助組
成物。3. The composition for swallowing according to claim 1, wherein the gel has an adhesion of 1 when eaten.
An easy-swallowing auxiliary composition characterized by being at most 00 g / m 2 .
嚥下補助組成物からなる食品用組成物。4. A food composition comprising the swallowing aid composition according to claim 1.
嚥下補助組成物からなる医薬品用組成物。5. A pharmaceutical composition comprising the auxiliary swallowing composition according to any one of claims 1 to 3.
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