JP2000044455A - Dermal external agent - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a dermal external agent having excellent functional characteristic and a dampness keeping property by including a vegetable squalane containing a specific amount of isoparaffin fraction having a specific melting point. SOLUTION: This dermal external agent is obtained by subjecting a vegetable oil (e.g. soybean oil or a germ oil) to hydrogenation and fractionating extraction and contains a vegetable squalane containing >=5 wt.% of isoparaffin fraction having 25-40 deg.C melting point in an amount of preferably 0.01-100 wt.% based on a total weight of the composition. As a use shape of the external agent, e.g. an ointment, a cream, a lotion, a latex, a pack or a cosmetic oil is preferably exemplified. Further, as an oil agent mixed with the objective external agent, a known external base agent, e.g. a silicone oil such as methylphenylpolysiloxane or hydrocarbons such as paraffin can be used other than the squalane.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to an external preparation for skin having excellent sensory characteristics and moisturizing ability.

[0002]

2. Description of the Related Art External preparations for skin have various effects such as skin protective action, softening action and occlusive action by the functions of the oils to be incorporated, and their effects are higher than those of skin external preparations containing no oils.

However, oils which are liquid at room temperature, such as squalane, that is, oils having a melting point of 20 ° C. or less are mixed with an oily feeling,
It causes stickiness and lowers palatability. On the other hand, compounding only oils that are solid at room temperature, such as lecithin and cholesterol ester, that is, oils having a melting point of 40 ° C. or more, increases the hardness of the emulsion and makes it difficult to apply it to the skin. There are many. Thus, it has been difficult to obtain a skin external preparation having excellent sensory characteristics.

[0004]

In view of such circumstances, the present inventors have aimed at obtaining a skin external preparation having an excellent functional surface, and have an excellent feeling in use, no oiliness, no stickiness, and a good skin familiarity. As a result of various studies on a good oil agent, a composition containing vegetable squalane containing an isoparaffin fraction having a melting point of 25 to 40 ° C. in an amount of 5% by weight or more has excellent sensory characteristics, and is also unexpectedly excellent in moisturizing ability. The present invention has been completed and the object of the present invention is to provide an external preparation for skin having excellent sensory characteristics and moisturizing ability.

[0005]

SUMMARY OF THE INVENTION The above-mentioned object is to achieve a melting point of 2.
It is achieved by an external preparation for skin characterized by containing a vegetable squalane containing 5% by weight or more of an isoparaffin fraction at 5 to 40 ° C.

[0006]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, embodiments of the present invention will be described in detail.

[0007] The plant squalane used in the present invention comprises:
It is prepared by hydrogenating and fractionating and extracting vegetable oil.
What is necessary is just to contain an isoparaffin fraction having a melting point of 25 to 40 ° C in an amount of 5% by weight or more. Rice bran oil, soybean oil, rice germ oil and the like can be mentioned as the origin, and for example, Sarakos RS manufactured by Nisshin Seimitsu Oil Co., Ltd. can be used, but not limited thereto. The amount of the vegetable squalane in the present external preparation is preferably 0.01 to 100%, particularly preferably 0.1 to 80%, based on the total weight of the composition. In addition, the measurement of the ratio of isoparaffin having a melting point of 25 to 40 ° C. was performed as follows. About 10 grams of a vegetable squalane sample is placed in a test tube, centrifuged at 40 ° C. (3000 rpm, 5 minutes), and the supernatant is collected and weighed. Thereafter, the mixture was cooled to 20 ° C. and centrifuged again (3.
000 rpm, 5 minutes), remove the supernatant and weigh the precipitate. The precipitate at 20 ° C was replaced by the weight of the supernatant at 40 ° C, and the ratio of isoparaffin having a melting point of 20 to 40 ° C was determined.

[0008] Examples of the form of use of the external preparation include ointments, creams, lotions, emulsions, packs, cosmetic oils and the like.

As the oil agent to be incorporated in the present external preparation, known external bases other than the above-mentioned vegetable squalane may be used. For example, silicone oils such as methylphenylpolysiloxane, dimethylpolysiloxane, cyclomethicone, paraffin, Hydrocarbons such as petrolatum, olive squalane, jojoba oil, castor oil, safflower oil, sunflower oil, olive oil,
Vegetable oils such as macadamia nut oil, beeswax, mokuro, waxes such as carnauba wax, octyldodecyl myristate, ester oils such as cetyl palmitate, cetanol, behenyl alcohol, higher alcohols such as stearyl alcohol, cholesterol, phytosterol,
Sterols such as branched fatty acid cholesterol ester, macadamia nut oil fatty acid phytosterol ester,
Processing oils such as hardened oils, higher fatty acids such as stearic acid, myristic acid, isostearic acid, oleic acid, iso-type long-chain fatty acids, anteiso-type long-chain fatty acids, triisosotearate glyceride, capryli / caprate glyceride,
And triglycerides such as glyceryl 2-ethylhexanoate. In addition, tar pigments, coloring pigments such as iron oxide, preservatives such as paraben and phenoxyethanol, anionic surfactants such as sodium cetyl sulfate, N-stearoyl-L-glutamate, and glycyrrhizinate, polyoxyethylene alkyl ether Nonionic surfactants such as polyoxyethylene fatty acid esters, polyoxyethylene polyhydric alcohol fatty acid esters, polyoxyethylene hydrogenated castor oil, polyhydric alcohol fatty acid esters, polyglycerin fatty acid esters, modified silicones, sucrose esters, etc., tetraalkylammonium Cationic surfactants such as salts, amphoteric surfactants such as betaine type, sulfobetaine type, sulfoamino acid type, natural surfactants such as lecithin, lysophosphatidylcholine, ceramide, cerebroside, and titanium oxide , Pigments such as zinc oxide, antioxidants such as dibutylhydroxytoluene, primary alcohols such as ethanol, polyhydric alcohols such as dipropylene glycol, 1,3-butylene glycol, glycerin, propylene glycol, sorbitol, malbitol, diglycerin, chlorides Inorganic salts such as sodium, magnesium chloride, sodium sulfate, potassium nitrate and sodium silicate; organic acid salts such as sodium succinate and sodium aspartate; ethanolamine hydrochloride;
Salts such as ammonium nitrate, arginine hydrochloride, phosphate, citrate, acetate, carbonate, trishydroxymethylaminomethane hydrochloride, diisopropylamine dichloroacetate, xanthan gum, carboxyvinyl polymer, carrageenan, alkyl-modified carboxyvinyl polymer, etc. Thickeners, chelating agents such as edetic acid, potassium hydroxide,
Neutralizing agents such as diisopropanolamine and triethanolamine, biopolymers such as hyaluronic acid and collagen, lactic acid bacteria, culture products such as yeast, chamomile, assembly, aloe, peach, carrot, horsetail, mulberry, peach leaves, Sage, loquat leaf, cucumber, vegetative extract, hibiscus, turmeric, rosemary, ogon, plant extracts such as licorice, serine, threonine, N-methylglycine,
Amino acids such as N-methyl-L-serine, aminobutyric acid, and hydroxyaminobutyric acid; ultraviolet absorbers such as hydroxymethoxybenzophenone sulfonate; vitamins A;
Vitamins such as B, C and E can be used according to the purpose, but are not limited thereto.

[0010]

The present invention will be described in detail below with reference to examples and comparative examples.

The sensory test and the moisturizing test were conducted by the following methods. (1) Sensory test method The samples of Examples and Comparative Examples were applied to the faces of 30 adult women, and the results were indicated by the number of persons who felt moisture after application, the number of persons who did not feel sticky or slimy.

(2) Moisturizing test (method for measuring water content of stratum corneum)
Method In the upper arm of 20 people, the amount of horny water 30 minutes after application of the sample was measured using Skicon-200 (manufactured by IBS) based on the method of Tagami et al. As a control, the measurement was performed at the same time when nothing was applied. According to the composition (% by weight) shown in Table 1, each component was heated and dissolved at 80 ° C., and then cooled to 30 ° C. while mixing and stirring. The compositions of Examples 1-3 were prepared.

[0013]

[Table 1]

The paste squalane in the table is 25% of the present invention.
It is a vegetable squalane containing 5% by weight or more of isoparaffin fraction at ４０40 ° C., and olive squalane is 25 to 40%.
It is a vegetable squalane without isoparaffin fraction at ℃.

Table 2 shows the results of the sensory test and the moisture retention test.

[0016]

[Table 2]

As is evident from Table 2, the external preparation for skin of the present invention (Example 1) exhibited superior sensory properties and a moisturizing effect as compared with the compositions of Comparative Examples 1 to 3.

Examples 2 to 4 (skin cream) The components (A) and (B) having the compositions (% by weight) shown in Table 3 were each dissolved by heating to 80 ° C, and then mixed and stirred to 30 ° C. Upon cooling, a skin cream was prepared.

[0019]

[Table 3]

Examples 5 to 7 (Lotion)

Each component having the composition (% by weight) shown in Table 4 was mixed and dissolved to prepare a lotion.

[0022]

[Table 4]

Examples 8 to 10 (skin cream) The components (A) and (B) having the compositions (% by weight) shown in Table 5 were each dissolved by heating at 80 ° C., mixed, and stirred.
After cooling to ℃, a skin cream was prepared.

[0024]

[Table 5]

Examples 11 to 15 (Cosmetic oil) The components (A) and (B) were dissolved by heating at 60 ° C with the compositions (% by weight) shown in Table 6, then mixed and stirred to 30 ° C. Upon cooling, a cosmetic oil was prepared.

[0026]

[Table 6]

The skin external preparations of these examples were excellent in sensory characteristics and moisturizing ability.

[0028]

As described above, it is apparent that the present invention provides a skin external preparation excellent in sensory characteristics and moisturizing ability.

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Claims (1)

[Claims] An external preparation for skin, comprising vegetable squalane containing 5% by weight or more of an isoparaffin fraction having a melting point of 25 to 40 ° C.