JOP20210220A1 - معالجة الداء النشواني من النوع خفيف السلسلة بتوليفة من أجسام مضادة أحادية النسيلة ضد سلاسل الغلوبيولين المناعي الخفيفة وجزيء الغشاء الخلوي cd38 على خلايا مناعية منتجة للأجسام المضادة وخلايا مناعية أخرى - Google Patents
معالجة الداء النشواني من النوع خفيف السلسلة بتوليفة من أجسام مضادة أحادية النسيلة ضد سلاسل الغلوبيولين المناعي الخفيفة وجزيء الغشاء الخلوي cd38 على خلايا مناعية منتجة للأجسام المضادة وخلايا مناعية أخرىInfo
- Publication number
- JOP20210220A1 JOP20210220A1 JOP/2021/0220A JOP20210220A JOP20210220A1 JO P20210220 A1 JOP20210220 A1 JO P20210220A1 JO P20210220 A JOP20210220 A JO P20210220A JO P20210220 A1 JOP20210220 A1 JO P20210220A1
- Authority
- JO
- Jordan
- Prior art keywords
- light chains
- immunoglobulin light
- amyloidosis
- antibody
- producing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
يتعلق هذا الاختراع بمعالجة الداء النشواني من النوع خفيف السلسلة بتوليفة من أجسام مضادة أحادية النسيلة ضد سلاسل الغلوبيولين المناعي الخفيفة وتكتلات من سلاسل الغلوبيولين المناعي الخفيفة وجزيء الغشاء الخلوي CD38 على خلايا مناعية منتجة للأجسام المضادة وخلايا مناعية أخرى. الشكل 1.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962804721P | 2019-02-12 | 2019-02-12 | |
PCT/US2019/066648 WO2020167376A1 (en) | 2019-02-12 | 2019-12-16 | Treatment of al amyloidosis with the combination of monoclonal antibodies against immunoglobulin light chains and the cd38 cell membrane molecule on antibody-producing and other immune cells |
Publications (1)
Publication Number | Publication Date |
---|---|
JOP20210220A1 true JOP20210220A1 (ar) | 2023-01-30 |
Family
ID=69182616
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2021/0220A JOP20210220A1 (ar) | 2019-02-12 | 2019-12-16 | معالجة الداء النشواني من النوع خفيف السلسلة بتوليفة من أجسام مضادة أحادية النسيلة ضد سلاسل الغلوبيولين المناعي الخفيفة وجزيء الغشاء الخلوي cd38 على خلايا مناعية منتجة للأجسام المضادة وخلايا مناعية أخرى |
Country Status (16)
Country | Link |
---|---|
US (1) | US20220213223A1 (ar) |
EP (1) | EP3923954A1 (ar) |
JP (1) | JP2022520572A (ar) |
KR (1) | KR20210143752A (ar) |
CN (1) | CN113924099A (ar) |
AU (1) | AU2019429147A1 (ar) |
BR (1) | BR112021015870A2 (ar) |
CA (1) | CA3129890A1 (ar) |
CL (1) | CL2021002140A1 (ar) |
EA (1) | EA202192235A1 (ar) |
IL (1) | IL285480A (ar) |
JO (1) | JOP20210220A1 (ar) |
MA (1) | MA54923A (ar) |
MX (1) | MX2021009687A (ar) |
SG (1) | SG11202108767PA (ar) |
WO (1) | WO2020167376A1 (ar) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2022522889A (ja) | 2019-03-05 | 2022-04-20 | プロシーナ バイオサイエンシーズ リミテッド | Alアミロイドーシスを処置する方法 |
IL300059A (en) | 2020-07-23 | 2023-03-01 | Othair Prothena Ltd | Anti-Abata antibodies |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030147882A1 (en) | 1998-05-21 | 2003-08-07 | Alan Solomon | Methods for amyloid removal using anti-amyloid antibodies |
SI2511297T1 (sl) | 2004-02-06 | 2015-07-31 | Morphosys Ag | Proti -CD38 humana protitelesa in njihova uporaba |
EP2535355B1 (en) | 2005-03-23 | 2019-01-02 | Genmab A/S | Antibodies against CD38 for treatment of multiple myeloma |
AU2008345022B2 (en) | 2007-12-28 | 2014-11-06 | Prothena Biosciences Limited | Treatment and prophylaxis of amyloidosis |
WO2011154453A1 (en) | 2010-06-09 | 2011-12-15 | Genmab A/S | Antibodies against human cd38 |
KR102196009B1 (ko) | 2011-10-25 | 2021-01-04 | 프로테나 바이오사이언시즈 리미티드 | 항체 제형 및 방법 |
US9364542B2 (en) | 2011-10-28 | 2016-06-14 | Excelse Bio, Inc. | Protein formulations containing amino acids |
CR20170526A (es) | 2015-05-20 | 2018-04-03 | Janssen Biotech Inc | ANTICUERPOS ANTI-CD38 PARA EL TRATAMIENTO DE AMILOIDOSIS DE CADENA LIGERA y OTRAS ENFERMEDADES MALIGNAS HEMATOLÓGICAS POSITIVAS PARA CD38 |
MD3827845T2 (ro) | 2015-11-03 | 2022-09-30 | Janssen Biotech Inc | Formulări subcutanate de anticorpi anti-CD38 și utilizări ale acestora |
PT3478713T (pt) * | 2016-06-30 | 2022-05-27 | Prothena Biosciences Ltd | Composições para tratamento da amiloidose |
-
2019
- 2019-12-16 CN CN201980094744.5A patent/CN113924099A/zh active Pending
- 2019-12-16 MA MA054923A patent/MA54923A/fr unknown
- 2019-12-16 EP EP19839484.3A patent/EP3923954A1/en active Pending
- 2019-12-16 JP JP2021547075A patent/JP2022520572A/ja active Pending
- 2019-12-16 CA CA3129890A patent/CA3129890A1/en active Pending
- 2019-12-16 JO JOP/2021/0220A patent/JOP20210220A1/ar unknown
- 2019-12-16 KR KR1020217029118A patent/KR20210143752A/ko unknown
- 2019-12-16 BR BR112021015870A patent/BR112021015870A2/pt unknown
- 2019-12-16 US US17/429,876 patent/US20220213223A1/en active Pending
- 2019-12-16 AU AU2019429147A patent/AU2019429147A1/en active Pending
- 2019-12-16 SG SG11202108767PA patent/SG11202108767PA/en unknown
- 2019-12-16 WO PCT/US2019/066648 patent/WO2020167376A1/en active Application Filing
- 2019-12-16 EA EA202192235A patent/EA202192235A1/ru unknown
- 2019-12-16 MX MX2021009687A patent/MX2021009687A/es unknown
-
2021
- 2021-08-09 IL IL285480A patent/IL285480A/en unknown
- 2021-08-12 CL CL2021002140A patent/CL2021002140A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
BR112021015870A2 (pt) | 2021-11-03 |
WO2020167376A1 (en) | 2020-08-20 |
CL2021002140A1 (es) | 2022-04-18 |
US20220213223A1 (en) | 2022-07-07 |
CN113924099A (zh) | 2022-01-11 |
CA3129890A1 (en) | 2020-08-20 |
SG11202108767PA (en) | 2021-09-29 |
AU2019429147A1 (en) | 2021-09-09 |
KR20210143752A (ko) | 2021-11-29 |
EP3923954A1 (en) | 2021-12-22 |
EA202192235A1 (ru) | 2022-01-19 |
WO2020167376A8 (en) | 2020-10-29 |
MX2021009687A (es) | 2021-12-10 |
IL285480A (en) | 2021-09-30 |
MA54923A (fr) | 2021-12-22 |
JP2022520572A (ja) | 2022-03-31 |
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