ITUA20164448A1 - Metodo metagenomico per la diagnosi in vitro di disbiosi intestinale. - Google Patents

Metodo metagenomico per la diagnosi in vitro di disbiosi intestinale.

Info

Publication number
ITUA20164448A1
ITUA20164448A1 ITUA2016A004448A ITUA20164448A ITUA20164448A1 IT UA20164448 A1 ITUA20164448 A1 IT UA20164448A1 IT UA2016A004448 A ITUA2016A004448 A IT UA2016A004448A IT UA20164448 A ITUA20164448 A IT UA20164448A IT UA20164448 A1 ITUA20164448 A1 IT UA20164448A1
Authority
IT
Italy
Prior art keywords
vitro diagnosis
intestinal dysbiosis
metagenomic
metagenomic method
dysbiosis
Prior art date
Application number
ITUA2016A004448A
Other languages
English (en)
Inventor
Lorenza Putignani
Chierico Federica Del
Original Assignee
Ospedale Pediatrico Bambino Gesù
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ospedale Pediatrico Bambino Gesù filed Critical Ospedale Pediatrico Bambino Gesù
Priority to ITUA2016A004448A priority Critical patent/ITUA20164448A1/it
Priority to EP17755261.9A priority patent/EP3472611B1/en
Priority to CN201780037617.2A priority patent/CN109642895A/zh
Priority to PCT/IT2017/000119 priority patent/WO2017216820A1/en
Priority to CA3027832A priority patent/CA3027832A1/en
Priority to US16/310,760 priority patent/US20190136299A1/en
Priority to ES17755261T priority patent/ES2982081T3/es
Publication of ITUA20164448A1 publication Critical patent/ITUA20164448A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B10/00—ICT specially adapted for evolutionary bioinformatics, e.g. phylogenetic tree construction or analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Theoretical Computer Science (AREA)
  • Epidemiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Primary Health Care (AREA)
  • Software Systems (AREA)
  • Physiology (AREA)
ITUA2016A004448A 2016-06-16 2016-06-16 Metodo metagenomico per la diagnosi in vitro di disbiosi intestinale. ITUA20164448A1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITUA2016A004448A ITUA20164448A1 (it) 2016-06-16 2016-06-16 Metodo metagenomico per la diagnosi in vitro di disbiosi intestinale.
EP17755261.9A EP3472611B1 (en) 2016-06-16 2017-06-16 Metagenomic method for in vitro diagnosis of gut dysbiosis
CN201780037617.2A CN109642895A (zh) 2016-06-16 2017-06-16 用于体外诊断肠道生态失调的宏基因组方法
PCT/IT2017/000119 WO2017216820A1 (en) 2016-06-16 2017-06-16 Metagenomic method for in vitro diagnosis of gut dysbiosis
CA3027832A CA3027832A1 (en) 2016-06-16 2017-06-16 Metagenomic method for in vitro diagnosis of gut dysbiosis
US16/310,760 US20190136299A1 (en) 2016-06-16 2017-06-16 Metagenomic method for in vitro diagnosis of gut dysbiosis
ES17755261T ES2982081T3 (es) 2016-06-16 2017-06-16 Método metagenómico para el diagnóstico in vitro de la disbiosis intestinal

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUA2016A004448A ITUA20164448A1 (it) 2016-06-16 2016-06-16 Metodo metagenomico per la diagnosi in vitro di disbiosi intestinale.

Publications (1)

Publication Number Publication Date
ITUA20164448A1 true ITUA20164448A1 (it) 2017-12-16

Family

ID=57133340

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUA2016A004448A ITUA20164448A1 (it) 2016-06-16 2016-06-16 Metodo metagenomico per la diagnosi in vitro di disbiosi intestinale.

Country Status (7)

Country Link
US (1) US20190136299A1 (it)
EP (1) EP3472611B1 (it)
CN (1) CN109642895A (it)
CA (1) CA3027832A1 (it)
ES (1) ES2982081T3 (it)
IT (1) ITUA20164448A1 (it)
WO (1) WO2017216820A1 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200192889A1 (en) * 2017-08-16 2020-06-18 GenoRx Co.,Ltd A method of building gut microbiota database and a detection system of gut microbiota
IT201800011030A1 (it) * 2018-12-12 2020-06-12 Artemisia Lab Srl Metodo per la determinazione quali-quantitativa del microbiota intestinale
KR20210149127A (ko) * 2019-04-03 2021-12-08 4디 파마 코르크 리미티드 질환의 진단 방법
WO2021243380A1 (en) * 2020-05-29 2021-12-02 Figene, Llc Augmentation of fibroblast cell therapy efficacy by microbiome manipulation
WO2022159838A1 (en) * 2021-01-22 2022-07-28 Idbydna Inc. Methods and systems for metagenomics analysis
WO2022170124A1 (en) * 2021-02-04 2022-08-11 Idbydna Inc. Systems and methods for analysis of samples

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011140208A2 (en) * 2010-05-04 2011-11-10 University Of Florida Research Foundation, Inc. Methods and compositions for diagnosing and treating autoimmune disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015066625A1 (en) * 2013-11-01 2015-05-07 Washington University Methods to establish and restore normal gut microbiota function of subject in need thereof
CN103773887A (zh) * 2014-02-19 2014-05-07 大连大学 一种小鼠肠道菌群失调eric-pcr指纹图谱的制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011140208A2 (en) * 2010-05-04 2011-11-10 University Of Florida Research Foundation, Inc. Methods and compositions for diagnosing and treating autoimmune disorders

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
EMILY B. HOLLISTER ET AL: "Structure and function of the healthy pre-adolescent pediatric gut microbiome", MICROBIOME, vol. 3, no. 1, 26 August 2015 (2015-08-26), XP055339318, DOI: 10.1186/s40168-015-0101-x *
GEMMA LOUISE KAY ET AL: "Differences in the Faecal Microbiome in Schistosoma haematobium Infected Children vs. Uninfected Children", PLOS NEGLECTED TROPICAL DISEASES, 1 January 2015 (2015-01-01), United States, pages 1 - 14, XP055339317, Retrieved from the Internet <URL:http://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0003861&type=printable> DOI: 10.1371/journal.pntd.0003861 *
N. O. KAAKOUSH ET AL: "Microbial Dysbiosis in Pediatric Patients with Crohn's Disease", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 50, no. 10, 1 October 2012 (2012-10-01), US, pages 3258 - 3266, XP055237520, ISSN: 0095-1137, DOI: 10.1128/JCM.01396-12 *
OHAD MANOR ET AL: "Metagenomic evidence for taxonomic dysbiosis and functional imbalance in the gastrointestinal tracts of children with cystic fibrosis", SCIENTIFIC REPORTS, vol. 6, 4 March 2016 (2016-03-04), pages 22493, XP055339001, DOI: 10.1038/srep22493 *
SUSANNE MUELLER ET AL: "Differences in Fecal Microbiota in Different European Study Populations in Relation to Age, Gender, and Country: a Cross-Sectional Study", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 72, no. 2, 1 February 2006 (2006-02-01), pages 1027 - 1033, XP002623954, ISSN: 0099-2240, DOI: 10.1128/AEM.72.2.1027-1033.2006 *

Also Published As

Publication number Publication date
US20190136299A1 (en) 2019-05-09
CN109642895A (zh) 2019-04-16
CA3027832A1 (en) 2017-12-21
EP3472611C0 (en) 2024-05-15
WO2017216820A1 (en) 2017-12-21
EP3472611A1 (en) 2019-04-24
ES2982081T3 (es) 2024-10-14
EP3472611B1 (en) 2024-05-15

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