IT201800011030A1 - Metodo per la determinazione quali-quantitativa del microbiota intestinale - Google Patents

Metodo per la determinazione quali-quantitativa del microbiota intestinale

Info

Publication number
IT201800011030A1
IT201800011030A1 IT102018000011030A IT201800011030A IT201800011030A1 IT 201800011030 A1 IT201800011030 A1 IT 201800011030A1 IT 102018000011030 A IT102018000011030 A IT 102018000011030A IT 201800011030 A IT201800011030 A IT 201800011030A IT 201800011030 A1 IT201800011030 A1 IT 201800011030A1
Authority
IT
Italy
Prior art keywords
quali
quantitative determination
intestinal microbiota
microbiota
intestinal
Prior art date
Application number
IT102018000011030A
Other languages
English (en)
Inventor
Concetta Cafiero
Marina Trombetti
Erika Cione
Filippo Cocozza
Original Assignee
Artemisia Lab Srl
Galascreen Srl
Marina Trombetti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Artemisia Lab Srl, Galascreen Srl, Marina Trombetti filed Critical Artemisia Lab Srl
Priority to IT102018000011030A priority Critical patent/IT201800011030A1/it
Publication of IT201800011030A1 publication Critical patent/IT201800011030A1/it

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
IT102018000011030A 2018-12-12 2018-12-12 Metodo per la determinazione quali-quantitativa del microbiota intestinale IT201800011030A1 (it)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IT102018000011030A IT201800011030A1 (it) 2018-12-12 2018-12-12 Metodo per la determinazione quali-quantitativa del microbiota intestinale

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102018000011030A IT201800011030A1 (it) 2018-12-12 2018-12-12 Metodo per la determinazione quali-quantitativa del microbiota intestinale

Publications (1)

Publication Number Publication Date
IT201800011030A1 true IT201800011030A1 (it) 2020-06-12

Family

ID=66049420

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102018000011030A IT201800011030A1 (it) 2018-12-12 2018-12-12 Metodo per la determinazione quali-quantitativa del microbiota intestinale

Country Status (1)

Country Link
IT (1) IT201800011030A1 (it)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2955232A1 (en) * 2014-06-12 2015-12-16 Peer Bork Method for diagnosing adenomas and/or colorectal cancer (CRC) based on analyzing the gut microbiome
WO2017216820A1 (en) * 2016-06-16 2017-12-21 Ospedale Pediatrico Bambino Gesu' Metagenomic method for in vitro diagnosis of gut dysbiosis
US20180080065A1 (en) * 2016-09-15 2018-03-22 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
WO2018115519A1 (en) * 2016-12-22 2018-06-28 Institut Gustave Roussy Microbiota composition, as a marker of responsiveness to anti-pd1/pd-l1/pd-l2 antibodies and use of microbial modulators for improving the efficacy of an anti-pd1/pd-l1/pd-l2 ab-based treatment

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2955232A1 (en) * 2014-06-12 2015-12-16 Peer Bork Method for diagnosing adenomas and/or colorectal cancer (CRC) based on analyzing the gut microbiome
WO2017216820A1 (en) * 2016-06-16 2017-12-21 Ospedale Pediatrico Bambino Gesu' Metagenomic method for in vitro diagnosis of gut dysbiosis
US20180080065A1 (en) * 2016-09-15 2018-03-22 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
WO2018115519A1 (en) * 2016-12-22 2018-06-28 Institut Gustave Roussy Microbiota composition, as a marker of responsiveness to anti-pd1/pd-l1/pd-l2 antibodies and use of microbial modulators for improving the efficacy of an anti-pd1/pd-l1/pd-l2 ab-based treatment

Non-Patent Citations (30)

* Cited by examiner, † Cited by third party
Title
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CLAVEL T; DESMARCHELIER C; HALLER D; GERARD P; ROHN S; LEPAGE P; DANIEL H: "Intestinal microbiota in metabolic diseases: from bacterial community structure and functions to species of pathophysiological relevance", GUT MICROBES, vol. 5, 2014, pages 544 - 51
DANIEL E ALMONACID ET AL: "16S rRNA gene sequencing and healthy reference ranges for 28 clinically relevant microbial taxa from the human gut microbiome", 3 May 2017 (2017-05-03), pages 1 - 15, XP055610413, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414997/pdf/pone.0176555.pdf> [retrieved on 20190801] *
EMILEY A. ELOE-FADROSH ET AL: "Functional Dynamics of the Gut Microbiome in Elderly People during Probiotic Consumption", MBIO, vol. 6, no. 2, 14 April 2015 (2015-04-14), pages e00231 - 15, XP055432493, DOI: 10.1128/mBio.00231-15 *
FRASER CM; RINGEL BACKHED F, Y; SANDERS ME; SARTOR RB; SHERMAN PM ET AL.: "Defining a healthy human gut microbiome: current concepts, future directions, and clinical applications", HOST CELL MICROBE, vol. 12, 2012, pages 611 - 22
GUARNER F; KHAN AG; GARISCH J; ELIAKIM R; GANGL A; THOMSON ET AL.: "World Gastroenterology Organization Global Guidelines: probiotics and prebiotics", J CLIN GASTROENTEROL, vol. 46, 2012, pages 468 - 81
HIROKAZU TSUJI ET AL: "Counting the Countless: Bacterial Quantification by Targeting rRNA Molecules to Explore the Human Gut Microbiota in Health and Disease", FRONTIERS IN MICROBIOLOGY, vol. 9, 29 June 2018 (2018-06-29), XP055610245, DOI: 10.3389/fmicb.2018.01417 *
JONNA JALANKA-TUOVINEN ET AL: "Faecal microbiota composition and host-microbe cross-talk following gastroenteritis and in postinfectious irritable bowel syndrome", GUT, vol. 63, no. 11, 2 November 2014 (2014-11-02), UK, pages 1737 - 1745, XP055610139, ISSN: 0017-5749, DOI: 10.1136/gutjnl-2013-305994 *
JOOSSENS MARIE ET AL: "Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives", 20110501, vol. 60, no. 5, 1 May 2011 (2011-05-01), pages 631 - 637, XP009186692, ISSN: 0017-5749, DOI: 10.1136/GUT.2010.223263 *
KARLSSON FH; TREMAROLI V; NOOKAEW I ET AL., NATURE, vol. 498, 2013, pages 99 - 10
LIU SHIRONG ET AL: "The Host Shapes the Gut Microbiota via Fecal MicroRNA", CELL HOST & MICROBE, ELSEVIER, NL, vol. 19, no. 1, 2 February 2016 (2016-02-02), pages 32 - 43, XP029386802, ISSN: 1931-3128, DOI: 10.1016/J.CHOM.2015.12.005 *
M, LYNCH RAUCH SV: "The potential for probiotic manipulation of the gastrointestinal microbiome", CURR OPIN BIOTECHNOL, vol. 23, 2017, pages 192 - 201
MARCHESI JR. ET AL., GUT., vol. 65, no. 2, February 2016 (2016-02-01), pages 330 - 9
MAYNARD CL; ELSON CO; HATTON RD; WEAVER CT: "Return interactions of the intestinal microbiota and immune system", NATURE, vol. 489, 2012, pages 231 - 241
NAVA GM; STAPPENBECK TS: "Diversity of the autochthonous colonies microbiota", GUT MICROBES, vol. 2, 2011, pages 99 - 104
OR'HARA AM; SHANAHAN F: "The gut flora as a forgotten organ", EMBO REP, vol. 7, 2006, pages 688 - 93, XP055083032, DOI: doi:10.1038/sj.embor.7400731
P. D. SCANLAN ET AL: "Culture-Independent Analyses of Temporal Variation of the Dominant Fecal Microbiota and Targeted Bacterial Subgroups in Crohn's Disease", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 44, no. 11, 1 November 2006 (2006-11-01), US, pages 3980 - 3988, XP055610217, ISSN: 0095-1137, DOI: 10.1128/JCM.00312-06 *
PRESCOTT SL; BJORKSTEN B: "Probiotics for the prevention or treatment of allergies diseases", J ALLERGY CLIN IMMUNOL, vol. 120, 2007, pages 255 - 62
QIN J, Y, Z, CAI ET AL., NATURE, vol. 490, 2012, pages 55 - 60
ROUND JL; MAZMANIAN SK: "The gut microbiota shapes intestinal immune responses in health and disease", NATURE REVIEWS IMMUNOLOGY, vol. 9, 2009, pages 313 - 323, XP055252815, DOI: doi:10.1038/nri2515
SCHIRMER MELANIE ET AL: "Dynamics of metatranscription in the inflammatory bowel disease gut microbiome", NATURE MICROBIOLOGY, NATURE PUBLISHING GROUP UK, LONDON, vol. 3, no. 3, 8 January 2018 (2018-01-08), pages 337 - 346, XP036431745, DOI: 10.1038/S41564-017-0089-Z *
SEUNGHA KANG ET AL: "Dysbiosis of fecal microbiota in Crohn?s disease patients as revealed by a custom phylogenetic microarray", INFLAMMATORY BOWEL DISEASES, vol. 16, no. 12, 1 December 2010 (2010-12-01), pages 2034 - 2042, XP055149327, ISSN: 1078-0998, DOI: 10.1002/ibd.21319 *
SINHA ET AL., BIOMARKERS PREV BIOMARKERS PREV., vol. 25, no. 2, February 2016 (2016-02-01), pages 407 - 416
THE SEKIROV; RUSSELL S; ANTUNES L; FINLAY B: "Gut microbiota in health and disease", PHYSIOL, vol. 90, 2010, pages 859 - 904, XP002674206, DOI: doi:10.1152/PHYSREV.00045.2009
TOMOYA YAMASHITA ET AL: "Gut Microbiota and Coronary Artery Disease", INTERNATIONAL HEART JOURNAL, vol. 57, no. 6, 1 January 2016 (2016-01-01), JP, pages 663 - 671, XP055525603, ISSN: 1349-2365, DOI: 10.1536/ihj.16-414 *
VIRGINIE LECOMTE ET AL: "Changes in Gut Microbiota in Rats Fed a High Fat Diet Correlate with Obesity-Associated Metabolic Parameters", PLOS ONE, vol. 10, no. 5, 18 May 2015 (2015-05-18), pages e0126931, XP055439774, DOI: 10.1371/journal.pone.0126931 *
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