ITTO20060273A1 - Metodi ed apparati per la selezione e/o il processamento di particellle, in particolare per la lisi selettiva e/o ottimizzata di cellule - Google Patents

Metodi ed apparati per la selezione e/o il processamento di particellle, in particolare per la lisi selettiva e/o ottimizzata di cellule

Info

Publication number
ITTO20060273A1
ITTO20060273A1 IT000273A ITTO20060273A ITTO20060273A1 IT TO20060273 A1 ITTO20060273 A1 IT TO20060273A1 IT 000273 A IT000273 A IT 000273A IT TO20060273 A ITTO20060273 A IT TO20060273A IT TO20060273 A1 ITTO20060273 A1 IT TO20060273A1
Authority
IT
Italy
Prior art keywords
selective
particles
selection
equipment
methods
Prior art date
Application number
IT000273A
Other languages
English (en)
Inventor
Melanie Abonnenc
Nicolo' Manaresi
Gianni Medoro
Original Assignee
Silicon Biosystem S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Silicon Biosystem S P A filed Critical Silicon Biosystem S P A
Priority to IT000273A priority Critical patent/ITTO20060273A1/it
Priority to CN2007800215779A priority patent/CN101484245B/zh
Priority to CA2649017A priority patent/CA2649017C/en
Priority to JP2009504847A priority patent/JP5518466B2/ja
Priority to DK07734282.2T priority patent/DK2010331T3/da
Priority to ES07734282T priority patent/ES2902701T3/es
Priority to PCT/IB2007/000963 priority patent/WO2007116312A2/en
Priority to US12/296,952 priority patent/US9914135B2/en
Priority to EP07734282.2A priority patent/EP2010331B1/en
Priority to EP21203012.6A priority patent/EP3960300A3/en
Publication of ITTO20060273A1 publication Critical patent/ITTO20060273A1/it
Priority to US15/828,384 priority patent/US10166549B2/en
Priority to US16/202,718 priority patent/US11198902B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/02—Separators
    • B03C5/022—Non-uniform field separators
    • B03C5/026—Non-uniform field separators using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/06—Hydrolysis; Cell lysis; Extraction of intracellular or cell wall material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0424—Dielectrophoretic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
IT000273A 2006-04-12 2006-04-12 Metodi ed apparati per la selezione e/o il processamento di particellle, in particolare per la lisi selettiva e/o ottimizzata di cellule ITTO20060273A1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT000273A ITTO20060273A1 (it) 2006-04-12 2006-04-12 Metodi ed apparati per la selezione e/o il processamento di particellle, in particolare per la lisi selettiva e/o ottimizzata di cellule
ES07734282T ES2902701T3 (es) 2006-04-12 2007-04-12 Métodos para la selección y/o procesamiento de partículas para lisis selectiva y/u optimizada de células
CA2649017A CA2649017C (en) 2006-04-12 2007-04-12 Methods and apparatus for the selection and/or processing of particles, in particular for the selective and/or optimised lysis of cells
JP2009504847A JP5518466B2 (ja) 2006-04-12 2007-04-12 細胞の選択的溶解および／または最適化溶解に代表される粒子の選択および／または処理のための方法ならびに装置
DK07734282.2T DK2010331T3 (da) 2006-04-12 2007-04-12 Fremgangsmåder til udvælgelse og/eller behandling af partikler til selektiv og/eller optimeret lysering af celler
CN2007800215779A CN101484245B (zh) 2006-04-12 2007-04-12 用于选择和/或处理粒子，具体地用于选择性地和/或最优化地溶解细胞的方法和装置
PCT/IB2007/000963 WO2007116312A2 (en) 2006-04-12 2007-04-12 Methods and apparatus for the selection and/or processing of particles, in particular for the selective and/or optimised lysis of cells
US12/296,952 US9914135B2 (en) 2006-04-12 2007-04-12 Methods and apparatus for the selection and/or processing of particles, in particular for the selective and/or optimised lysis of cells
EP07734282.2A EP2010331B1 (en) 2006-04-12 2007-04-12 Methods for the selection and/or processing of particles for selective and/or optimized lysis of cells
EP21203012.6A EP3960300A3 (en) 2006-04-12 2007-04-12 Method and apparatus for the selection and/or processing of particles
US15/828,384 US10166549B2 (en) 2006-04-12 2017-11-30 Methods and apparatus for the selection and/or processing of particles, in particular for the selective and/or optimised lysis of cells
US16/202,718 US11198902B2 (en) 2006-04-12 2018-11-28 Methods and apparatus for the selection and/or processing of particles, in particular for the selective and/or optimised lysis of cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000273A ITTO20060273A1 (it) 2006-04-12 2006-04-12 Metodi ed apparati per la selezione e/o il processamento di particellle, in particolare per la lisi selettiva e/o ottimizzata di cellule

Publications (1)

Publication Number Publication Date
ITTO20060273A1 true ITTO20060273A1 (it) 2007-10-13

Family

ID=38491137

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000273A ITTO20060273A1 (it) 2006-04-12 2006-04-12 Metodi ed apparati per la selezione e/o il processamento di particellle, in particolare per la lisi selettiva e/o ottimizzata di cellule

Country Status (9)

Country Link
US (3) US9914135B2 (it)
EP (2) EP2010331B1 (it)
JP (1) JP5518466B2 (it)
CN (1) CN101484245B (it)
CA (1) CA2649017C (it)
DK (1) DK2010331T3 (it)
ES (1) ES2902701T3 (it)
IT (1) ITTO20060273A1 (it)
WO (1) WO2007116312A2 (it)

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Also Published As

Publication number Publication date
US20190143340A1 (en) 2019-05-16
CA2649017A1 (en) 2007-10-18
CA2649017C (en) 2014-12-02
US20090220974A1 (en) 2009-09-03
JP5518466B2 (ja) 2014-06-11
WO2007116312A2 (en) 2007-10-18
EP2010331A2 (en) 2009-01-07
US20180161782A1 (en) 2018-06-14
EP3960300A2 (en) 2022-03-02
EP2010331B1 (en) 2021-10-27
WO2007116312A3 (en) 2007-12-21
US10166549B2 (en) 2019-01-01
DK2010331T3 (da) 2022-01-10
US11198902B2 (en) 2021-12-14
EP3960300A3 (en) 2022-06-22
CN101484245A (zh) 2009-07-15
CN101484245B (zh) 2012-06-20
ES2902701T3 (es) 2022-03-29
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US9914135B2 (en) 2018-03-13
JP2009533044A (ja) 2009-09-17

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