ITRM970441A0 - - Google Patents

Info

Publication number
ITRM970441A0
ITRM970441A0 ITRM970441A ITRM970441A ITRM970441A0 IT RM970441 A0 ITRM970441 A0 IT RM970441A0 IT RM970441 A ITRM970441 A IT RM970441A IT RM970441 A ITRM970441 A IT RM970441A IT RM970441 A0 ITRM970441 A0 IT RM970441A0
Authority
IT
Italy
Application number
ITRM970441A
Other languages
Italian (it)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of ITRM970441A0 publication Critical patent/ITRM970441A0/it
Priority to IT97RM000441A priority Critical patent/IT1296305B1/it
Priority to PCT/IT1998/000202 priority patent/WO1999003878A2/en
Priority to EP98932516A priority patent/EP1019434B1/en
Priority to JP2000503100A priority patent/JP3325017B2/ja
Priority to US09/462,932 priority patent/US6339160B1/en
Priority to ES98932516T priority patent/ES2206955T3/es
Priority to DE69818698T priority patent/DE69818698T2/de
Priority to AU82418/98A priority patent/AU8241898A/en
Publication of ITRM970441A1 publication Critical patent/ITRM970441A1/it
Application granted granted Critical
Publication of IT1296305B1 publication Critical patent/IT1296305B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IT97RM000441A 1997-07-17 1997-07-17 Inibitori di metalloproteinasi loro uso terapeutico e procedimento per la produzione del composto di partenza nella loro IT1296305B1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT97RM000441A IT1296305B1 (it) 1997-07-17 1997-07-17 Inibitori di metalloproteinasi loro uso terapeutico e procedimento per la produzione del composto di partenza nella loro
US09/462,932 US6339160B1 (en) 1997-07-17 1998-07-17 Metalloproteinase inhibitors, their therapeutic use and process for the production of the starting compound in the synthesis thereof
EP98932516A EP1019434B1 (en) 1997-07-17 1998-07-17 Inhibitors of metalloproteinases, their therapeutic use, and process for the production of the starting compound in their synthesis
JP2000503100A JP3325017B2 (ja) 1997-07-17 1998-07-17 新規メタロプロテアーゼ阻害剤、その治療的利用およびその合成における開始化合物の製造方法
PCT/IT1998/000202 WO1999003878A2 (en) 1997-07-17 1998-07-17 Inhibitors of metalloproteinases, their therapeutic use, and process for the production of the starting compound in their synthesis
ES98932516T ES2206955T3 (es) 1997-07-17 1998-07-17 Inhibidores de metaloproteinasas, su empleo terapeutico y procedimiento para la produccion del compuesto de partida en su sintesis.
DE69818698T DE69818698T2 (de) 1997-07-17 1998-07-17 Inhibitoren von metalloproteinasen, ihre therapeutische verwendung und verfahren zur herstellung der grundstoffe für ihre synthese
AU82418/98A AU8241898A (en) 1997-07-17 1998-07-17 New metalloproteinase inhibitors, their therapeutic use and process for the pro duction of the starting compound in the synthesis thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97RM000441A IT1296305B1 (it) 1997-07-17 1997-07-17 Inibitori di metalloproteinasi loro uso terapeutico e procedimento per la produzione del composto di partenza nella loro

Publications (3)

Publication Number Publication Date
ITRM970441A0 true ITRM970441A0 (enExample) 1997-07-17
ITRM970441A1 ITRM970441A1 (it) 1999-01-17
IT1296305B1 IT1296305B1 (it) 1999-06-25

Family

ID=11405183

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97RM000441A IT1296305B1 (it) 1997-07-17 1997-07-17 Inibitori di metalloproteinasi loro uso terapeutico e procedimento per la produzione del composto di partenza nella loro

Country Status (8)

Country Link
US (1) US6339160B1 (enExample)
EP (1) EP1019434B1 (enExample)
JP (1) JP3325017B2 (enExample)
AU (1) AU8241898A (enExample)
DE (1) DE69818698T2 (enExample)
ES (1) ES2206955T3 (enExample)
IT (1) IT1296305B1 (enExample)
WO (1) WO1999003878A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040122011A1 (en) * 1998-12-23 2004-06-24 Pharmacia Corporation Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy
US6683165B1 (en) 1999-04-13 2004-01-27 Genome Therapeutics Corporation Human gene relating to respiratory diseases and obesity
GB9922577D0 (en) * 1999-09-23 1999-11-24 Center For Clinical & Basic Re Substituted phosphinate based peptide derivatives
WO2001078894A2 (en) * 2000-04-13 2001-10-25 Schering Corporation Novel human gene relating to respiratory diseases, obesity, and inflammatory bowel disease
US7364719B2 (en) * 2002-10-04 2008-04-29 The United States Of America As Represented By The Department Of Health And Human Services Vasoregulating compounds and methods of their use
AU2003295422B2 (en) * 2002-11-07 2009-01-29 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services A new target for angiogenesis and anti-angiogenesis therapy
BRPI0400284A (pt) * 2004-03-18 2005-11-01 Fundacao Oswaldo Cruz Uso de dm 43 e seus fragmentos como inibidor de metaloproteases de matriz
DK2041181T3 (da) * 2006-06-08 2011-08-29 Helmholtz Zentrum Muenchen Specifikke proteaseinhibitorer og deres anvendelse i cancerterapi
GB0708507D0 (en) * 2007-05-02 2007-06-13 Queen Mary & Westfield College Substituted phosphonates and their use
WO2017117130A1 (en) 2015-12-28 2017-07-06 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for inhibiting human immunodeficiency virus (hiv) release from infected cells
EP3860608A1 (en) 2018-10-04 2021-08-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Egfr inhibitors for treating keratodermas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0401963A1 (en) 1989-04-13 1990-12-12 Beecham Group p.l.c. Phosphonopeptides with collagenase inhibiting activity
IT1242002B (it) * 1990-10-03 1994-02-02 Polifarma Spa Composti con attivita' farmacologica antiipertensiva, analgesica, immunomodulante e antiinfiammatoria, che presentano nella molecola una sequenza di tre radicali, essendo alfa-amminoacido quello centrale
IT1277904B1 (it) * 1995-08-07 1997-11-12 Polifarma Spa Metodo per determinare l'attivita' terapeutica di composti inibitori di metalloproteinasi, nuovi composti inibitori, e loro impiego

Also Published As

Publication number Publication date
IT1296305B1 (it) 1999-06-25
AU8241898A (en) 1999-02-10
ITRM970441A1 (it) 1999-01-17
EP1019434B1 (en) 2003-10-01
WO1999003878A3 (en) 1999-04-01
JP3325017B2 (ja) 2002-09-17
WO1999003878A2 (en) 1999-01-28
JP2001525315A (ja) 2001-12-11
DE69818698D1 (de) 2003-11-06
DE69818698T2 (de) 2004-08-19
US6339160B1 (en) 2002-01-15
EP1019434A2 (en) 2000-07-19
ES2206955T3 (es) 2004-05-16

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Legal Events

Date Code Title Description
0001 Granted