BRPI0400284A - Uso de dm 43 e seus fragmentos como inibidor de metaloproteases de matriz - Google Patents
Uso de dm 43 e seus fragmentos como inibidor de metaloproteases de matrizInfo
- Publication number
- BRPI0400284A BRPI0400284A BR0400284-9A BRPI0400284A BRPI0400284A BR PI0400284 A BRPI0400284 A BR PI0400284A BR PI0400284 A BRPI0400284 A BR PI0400284A BR PI0400284 A BRPI0400284 A BR PI0400284A
- Authority
- BR
- Brazil
- Prior art keywords
- matrix metalloprotease
- metalloprotease inhibitor
- fragments
- inhibitor
- relates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Hospice & Palliative Care (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"USO DE DM43 E SEUS FRAGMENTOS COMO INIBIDOR DE METALOPROTEASES DE MATRIZ". A presente invenção está relacionada ao uso da proteína DM43 como inibidor de metaloproteases. Mais particularmente, a presente invenção está relacionada ao uso de DM43 para terapêutica de patologias como cânceres e osteoartrite, dependentes da inibição de metaloproteases de matriz, baseando-se na identidade estrutural com as SVMPs.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR0400284-9A BRPI0400284A (pt) | 2004-03-18 | 2004-03-18 | Uso de dm 43 e seus fragmentos como inibidor de metaloproteases de matriz |
PCT/BR2005/000036 WO2005087252A1 (en) | 2004-03-18 | 2005-03-18 | Use of dm43 and its fragments as matrix metalloproteinases inhibitor |
EP05714403A EP1786452A1 (en) | 2004-03-18 | 2005-03-18 | Use of dm43 and its fragments as matrix metalloproteinases inhibitor |
US10/593,527 US20080249005A1 (en) | 2004-03-18 | 2005-03-18 | Use of Dm43 and Its Fragments as Matrix Metalloproteinases Inhibitor |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR0400284-9A BRPI0400284A (pt) | 2004-03-18 | 2004-03-18 | Uso de dm 43 e seus fragmentos como inibidor de metaloproteases de matriz |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0400284A true BRPI0400284A (pt) | 2005-11-01 |
Family
ID=34975334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0400284-9A BRPI0400284A (pt) | 2004-03-18 | 2004-03-18 | Uso de dm 43 e seus fragmentos como inibidor de metaloproteases de matriz |
Country Status (4)
Country | Link |
---|---|
US (1) | US20080249005A1 (pt) |
EP (1) | EP1786452A1 (pt) |
BR (1) | BRPI0400284A (pt) |
WO (1) | WO2005087252A1 (pt) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993023075A1 (en) * | 1992-05-14 | 1993-11-25 | Oncologix, Inc. | Treatment of vascular leakage syndrome and collagenase induced disease by administration of matrix metalloproteinase inhibitors |
IT1277904B1 (it) * | 1995-08-07 | 1997-11-12 | Polifarma Spa | Metodo per determinare l'attivita' terapeutica di composti inibitori di metalloproteinasi, nuovi composti inibitori, e loro impiego |
IT1296305B1 (it) * | 1997-07-17 | 1999-06-25 | Polifarma Spa | Inibitori di metalloproteinasi loro uso terapeutico e procedimento per la produzione del composto di partenza nella loro |
WO2001078894A2 (en) * | 2000-04-13 | 2001-10-25 | Schering Corporation | Novel human gene relating to respiratory diseases, obesity, and inflammatory bowel disease |
-
2004
- 2004-03-18 BR BR0400284-9A patent/BRPI0400284A/pt not_active Application Discontinuation
-
2005
- 2005-03-18 US US10/593,527 patent/US20080249005A1/en not_active Abandoned
- 2005-03-18 EP EP05714403A patent/EP1786452A1/en not_active Withdrawn
- 2005-03-18 WO PCT/BR2005/000036 patent/WO2005087252A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
US20080249005A1 (en) | 2008-10-09 |
WO2005087252A1 (en) | 2005-09-22 |
EP1786452A1 (en) | 2007-05-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B03A | Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette] | ||
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] | ||
B11N | Dismissal: publication cancelled [chapter 11.14 patent gazette] |
Free format text: REFERENTE A RPI NO 1977 DE 25/11/2008. |
|
B04C | Request for examination: application reinstated [chapter 4.3 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |