ITRM20050390A1 - Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico. - Google Patents

Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.

Info

Publication number
ITRM20050390A1
ITRM20050390A1 IT000390A ITRM20050390A ITRM20050390A1 IT RM20050390 A1 ITRM20050390 A1 IT RM20050390A1 IT 000390 A IT000390 A IT 000390A IT RM20050390 A ITRM20050390 A IT RM20050390A IT RM20050390 A1 ITRM20050390 A1 IT RM20050390A1
Authority
IT
Italy
Prior art keywords
receptors
egf
compounds
medical fields
specific salts
Prior art date
Application number
IT000390A
Other languages
English (en)
Italian (it)
Inventor
Sergio Baroni
Giancarlo Naccari
Original Assignee
Giuliani Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giuliani Spa filed Critical Giuliani Spa
Priority to IT000390A priority Critical patent/ITRM20050390A1/it
Priority to EP06766083A priority patent/EP1910275B1/en
Priority to PCT/IE2006/000076 priority patent/WO2007010514A2/en
Priority to CA002615978A priority patent/CA2615978A1/en
Priority to US11/989,033 priority patent/US8138357B2/en
Priority to NZ566044A priority patent/NZ566044A/en
Priority to AU2006271163A priority patent/AU2006271163B2/en
Priority to BRPI0613398-3A priority patent/BRPI0613398A2/pt
Priority to CN2006800300279A priority patent/CN101243043B/zh
Priority to JP2008522168A priority patent/JP5193862B2/ja
Publication of ITRM20050390A1 publication Critical patent/ITRM20050390A1/it
Priority to NO20080323A priority patent/NO20080323L/no
Priority to US13/397,245 priority patent/US8450506B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/64—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/54—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/10—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT000390A 2005-07-22 2005-07-22 Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico. ITRM20050390A1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT000390A ITRM20050390A1 (it) 2005-07-22 2005-07-22 Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.
NZ566044A NZ566044A (en) 2005-07-22 2006-07-24 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field
PCT/IE2006/000076 WO2007010514A2 (en) 2005-07-22 2006-07-24 Compounds and their salts specific to the ppar receptors and the egf receptors and their use in the medical field
CA002615978A CA2615978A1 (en) 2005-07-22 2006-07-24 Compounds and their salts specific to the ppar receptors and the egf receptors and their use in the medical field
US11/989,033 US8138357B2 (en) 2005-07-22 2006-07-24 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field
EP06766083A EP1910275B1 (en) 2005-07-22 2006-07-24 Compounds and their salts specific to the ppar receptors and the egf receptors and their use in the medical field
AU2006271163A AU2006271163B2 (en) 2005-07-22 2006-07-24 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field
BRPI0613398-3A BRPI0613398A2 (pt) 2005-07-22 2006-07-24 composto, uso do mesmo, e, composição farmacêutica
CN2006800300279A CN101243043B (zh) 2005-07-22 2006-07-24 Ppar受体和egf受体特异性化合物及其盐以及它们在医药领域中的用途
JP2008522168A JP5193862B2 (ja) 2005-07-22 2006-07-24 Ｐｐａｒ受容体及びｅｇｆ受容体に特異的な化合物及びそれらの塩並びに医療分野におけるそれらの使用
NO20080323A NO20080323L (no) 2005-07-22 2008-01-18 Forbindelser og deres salter som er spesifikke overfor PPAR-reseptorer og EGF-reseptorer og deres anvendlse innen medisinen
US13/397,245 US8450506B2 (en) 2005-07-22 2012-02-15 Compounds and their salts specific to the PPAR receptors and the EGF Receptors and their use in the medical field

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000390A ITRM20050390A1 (it) 2005-07-22 2005-07-22 Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.

Publications (1)

Publication Number Publication Date
ITRM20050390A1 true ITRM20050390A1 (it) 2007-01-23

Family

ID=37574984

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000390A ITRM20050390A1 (it) 2005-07-22 2005-07-22 Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.

Country Status (11)

Country Link
US (2) US8138357B2 (https=)
EP (1) EP1910275B1 (https=)
JP (1) JP5193862B2 (https=)
CN (1) CN101243043B (https=)
AU (1) AU2006271163B2 (https=)
BR (1) BRPI0613398A2 (https=)
CA (1) CA2615978A1 (https=)
IT (1) ITRM20050390A1 (https=)
NO (1) NO20080323L (https=)
NZ (1) NZ566044A (https=)
WO (1) WO2007010514A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20050390A1 (it) 2005-07-22 2007-01-23 Giuliani Spa Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.
ITRM20050389A1 (it) 2005-07-22 2007-01-23 Giuliani Spa Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.
IE20070129A1 (en) * 2007-02-28 2008-12-24 Giuliani Int Ltd Ppar-gamma agonists stimulate enteric defensin expression
ITMI20072429A1 (it) 2007-12-24 2009-06-25 Giuliani Int Ltd Composti per il trattamento selettivo della componente immuno-infiammatoria intestinale della malattia celiaca
UA107562C2 (uk) * 2008-12-05 2015-01-26 Спосіб лікування псоріазу
WO2010091894A2 (en) 2009-02-16 2010-08-19 Giuliani International Limited Methods of treating hair related conditions
CN109999017A (zh) * 2012-02-09 2019-07-12 诺格拉制药有限公司 治疗纤维化的方法
CN104284655B (zh) 2012-04-18 2017-10-27 诺格拉制药有限公司 治疗乳糖不耐受的方法
AR105911A1 (es) 2015-09-03 2017-11-22 Forma Therapeutics Inc Inhibidores de hdac8 bicíclicos fusionados [6,6]
WO2020152350A1 (en) 2019-01-25 2020-07-30 Nogra Pharma Limited Compositions for use in preventing acne
EP4495101A3 (en) 2019-02-08 2025-04-30 Nogra Pharma Limited Process of making 3-(4'-aminophenyl)-2-methoxypropionic acid, and analogs and intermediates thereof
TW202541791A (zh) 2023-12-20 2025-11-01 愛爾蘭商諾格拉製藥有限公司 痤瘡局部用調配物

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ITRM20050389A1 (it) 2005-07-22 2007-01-23 Giuliani Spa Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.
ITRM20050390A1 (it) 2005-07-22 2007-01-23 Giuliani Spa Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.
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ITMI20072429A1 (it) 2007-12-24 2009-06-25 Giuliani Int Ltd Composti per il trattamento selettivo della componente immuno-infiammatoria intestinale della malattia celiaca
UA107562C2 (uk) 2008-12-05 2015-01-26 Спосіб лікування псоріазу
WO2010091894A2 (en) 2009-02-16 2010-08-19 Giuliani International Limited Methods of treating hair related conditions

Also Published As

Publication number Publication date
CN101243043A (zh) 2008-08-13
EP1910275B1 (en) 2013-02-13
AU2006271163A1 (en) 2007-01-25
US20090118357A1 (en) 2009-05-07
JP2009502775A (ja) 2009-01-29
NZ566044A (en) 2012-06-29
US20120316230A1 (en) 2012-12-13
BRPI0613398A2 (pt) 2011-01-11
US8450506B2 (en) 2013-05-28
WO2007010514A3 (en) 2007-03-29
CA2615978A1 (en) 2007-01-25
NO20080323L (no) 2008-04-15
AU2006271163B2 (en) 2012-03-15
WO2007010514A2 (en) 2007-01-25
EP1910275A2 (en) 2008-04-16
US8138357B2 (en) 2012-03-20
JP5193862B2 (ja) 2013-05-08
CN101243043B (zh) 2013-03-20

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