ITPD930044A1 - Derivati solfatati dei lisogangliosidi - Google Patents

Derivati solfatati dei lisogangliosidi

Info

Publication number
ITPD930044A1
ITPD930044A1 IT93PD000044A ITPD930044A ITPD930044A1 IT PD930044 A1 ITPD930044 A1 IT PD930044A1 IT 93PD000044 A IT93PD000044 A IT 93PD000044A IT PD930044 A ITPD930044 A IT PD930044A IT PD930044 A1 ITPD930044 A1 IT PD930044A1
Authority
IT
Italy
Prior art keywords
lysogangliosides
sulphated derivatives
derivatives
group
sulphated
Prior art date
Application number
IT93PD000044A
Other languages
English (en)
Inventor
Aurelio Romeo
Gunter Kirschner
Carlo Chizzolini
Hari Manev
Laura Facci
Original Assignee
Fidia S P A In Amministrazione
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia S P A In Amministrazione filed Critical Fidia S P A In Amministrazione
Publication of ITPD930044A0 publication Critical patent/ITPD930044A0/it
Priority to IT93PD000044A priority Critical patent/IT1267955B1/it
Priority to AU63935/94A priority patent/AU685787B2/en
Priority to PCT/US1994/001966 priority patent/WO1994020516A1/en
Priority to ES94911404T priority patent/ES2157257T3/es
Priority to DE69427468T priority patent/DE69427468T2/de
Priority to EP94911404A priority patent/EP0688331B1/en
Priority to CA002157357A priority patent/CA2157357A1/en
Priority to AT94911404T priority patent/ATE202112T1/de
Priority to US08/530,267 priority patent/US5795869A/en
Priority to JP6520042A priority patent/JPH08507308A/ja
Publication of ITPD930044A1 publication Critical patent/ITPD930044A1/it
Application granted granted Critical
Publication of IT1267955B1 publication Critical patent/IT1267955B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invenzione si riferisce a nuovi derivati di lisogangliosidi N-ed N'-sostituiti, in cui N indica il gruppo aminico della sfingosina ed N' quello dello acido neuroaminico, ed in cui l'acile naturale è sostituito da un gruppo solfato o solfonato. Ulteriore oggetto dell'invenzione sono i corrispondenti derivati Osolfatati.
IT93PD000044A 1993-03-04 1993-03-04 Derivati solfatati dei lisogangliosidi IT1267955B1 (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT93PD000044A IT1267955B1 (it) 1993-03-04 1993-03-04 Derivati solfatati dei lisogangliosidi
DE69427468T DE69427468T2 (de) 1993-03-04 1994-03-04 Neue sulfatierte lyso-gangliosidederivate
PCT/US1994/001966 WO1994020516A1 (en) 1993-03-04 1994-03-04 New sulfated lyso-ganglioside derivatives
ES94911404T ES2157257T3 (es) 1993-03-04 1994-03-04 Nuevos derivados liso-gangliosidos sulfatados.
AU63935/94A AU685787B2 (en) 1993-03-04 1994-03-04 New sulfated lyso-ganglioside derivatives
EP94911404A EP0688331B1 (en) 1993-03-04 1994-03-04 New sulfated lyso-ganglioside derivatives
CA002157357A CA2157357A1 (en) 1993-03-04 1994-03-04 New sulfated lyso-ganglioside derivatives
AT94911404T ATE202112T1 (de) 1993-03-04 1994-03-04 Neue sulfatierte lyso-gangliosidederivate
US08/530,267 US5795869A (en) 1993-03-04 1994-03-04 Sulfated lyso-ganglioside derivatives
JP6520042A JPH08507308A (ja) 1993-03-04 1994-03-04 新規硫酸化リゾ−ガングリオシド誘導体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93PD000044A IT1267955B1 (it) 1993-03-04 1993-03-04 Derivati solfatati dei lisogangliosidi

Publications (3)

Publication Number Publication Date
ITPD930044A0 ITPD930044A0 (it) 1993-03-04
ITPD930044A1 true ITPD930044A1 (it) 1994-09-04
IT1267955B1 IT1267955B1 (it) 1997-02-18

Family

ID=11390208

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93PD000044A IT1267955B1 (it) 1993-03-04 1993-03-04 Derivati solfatati dei lisogangliosidi

Country Status (9)

Country Link
EP (1) EP0688331B1 (it)
JP (1) JPH08507308A (it)
AT (1) ATE202112T1 (it)
AU (1) AU685787B2 (it)
CA (1) CA2157357A1 (it)
DE (1) DE69427468T2 (it)
ES (1) ES2157257T3 (it)
IT (1) IT1267955B1 (it)
WO (1) WO1994020516A1 (it)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1238346B (it) * 1989-11-14 1993-07-13 Gangliosidi modificati e loro derivati funzionali.
JPH03246297A (ja) * 1990-02-22 1991-11-01 Nippon Koutai Kenkyusho:Kk ガングリオシド誘導体及びこれを含有する抗ｈｉｖ剤
IT1253832B (it) * 1991-08-01 1995-08-29 Fidia Spa Derivati di gangliosidi
IT1267956B1 (it) * 1993-03-04 1997-02-18 Fidia S P A In Amministrazione Derivati o-solfatati di gangliosidi e lisogangliosidi

Also Published As

Publication number Publication date
CA2157357A1 (en) 1994-09-15
AU6393594A (en) 1994-09-26
IT1267955B1 (it) 1997-02-18
DE69427468D1 (de) 2001-07-19
AU685787B2 (en) 1998-01-29
DE69427468T2 (de) 2002-04-18
EP0688331A1 (en) 1995-12-27
ES2157257T3 (es) 2001-08-16
JPH08507308A (ja) 1996-08-06
WO1994020516A1 (en) 1994-09-15
EP0688331B1 (en) 2001-06-13
ATE202112T1 (de) 2001-06-15
ITPD930044A0 (it) 1993-03-04

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19990210