ES2168276T3 - 1-arilsulfonil-3-fenil-1,4,5,6-tetrahidropiridazinas. - Google Patents

1-arilsulfonil-3-fenil-1,4,5,6-tetrahidropiridazinas.

Info

Publication number
ES2168276T3
ES2168276T3 ES93917006T ES93917006T ES2168276T3 ES 2168276 T3 ES2168276 T3 ES 2168276T3 ES 93917006 T ES93917006 T ES 93917006T ES 93917006 T ES93917006 T ES 93917006T ES 2168276 T3 ES2168276 T3 ES 2168276T3
Authority
ES
Spain
Prior art keywords
tetrahydropiridazines
arilsulfonil
phenyl
tetrahydropiridazinas
recontagers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93917006T
Other languages
English (en)
Inventor
Donald W Combs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Pharmaceutical Corp
Original Assignee
Ortho Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharmaceutical Corp filed Critical Ortho Pharmaceutical Corp
Application granted granted Critical
Publication of ES2168276T3 publication Critical patent/ES2168276T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650905—Six-membered rings having the nitrogen atoms in the positions 1 and 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

SE DESCRIBEN TETRAHIDROPIRIDAZINAS ONILO, 1FENILOCARBONILO, 1-FENILOTIOCARBONILO Y 1-FENILOFOSFENILO-3-ARILO PARA FAVORECER EL CRECIMIENTO DE LAS CELULAS DE LOS HUESOS PARA SER ANTAGONISTAS Y AGONISTAS DE LA PROGESTINA Y ENLAZAR CON EL RECEPTOR GABA A.
ES93917006T 1992-07-01 1993-07-01 1-arilsulfonil-3-fenil-1,4,5,6-tetrahidropiridazinas. Expired - Lifetime ES2168276T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90698492A 1992-07-01 1992-07-01
US8098693A 1993-06-21 1993-06-21

Publications (1)

Publication Number Publication Date
ES2168276T3 true ES2168276T3 (es) 2002-06-16

Family

ID=26764215

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93917006T Expired - Lifetime ES2168276T3 (es) 1992-07-01 1993-07-01 1-arilsulfonil-3-fenil-1,4,5,6-tetrahidropiridazinas.

Country Status (14)

Country Link
US (1) US5684151A (es)
EP (1) EP0650480B1 (es)
JP (1) JPH07508987A (es)
AT (1) ATE209189T1 (es)
AU (1) AU668206B2 (es)
BR (1) BR9306661A (es)
CA (1) CA2139307A1 (es)
DE (1) DE69331196T2 (es)
DK (1) DK0650480T3 (es)
ES (1) ES2168276T3 (es)
HU (1) HUT68424A (es)
NZ (1) NZ254534A (es)
PT (1) PT650480E (es)
WO (1) WO1994001412A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4430755A1 (de) * 1994-08-30 1996-03-07 Boehringer Mannheim Gmbh Neue Phosphanoxide, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US5707985A (en) * 1995-06-07 1998-01-13 Tanabe Seiyaku Co. Ltd. Naphthyl-, quinolyl- and isoquinolyl- sulfonamide derivatives as cell adhesion modulators
DE19632549A1 (de) 1996-08-13 1998-02-19 Merck Patent Gmbh Arylalkanoylpyridazine
DE19723722A1 (de) * 1997-05-30 1998-12-10 Schering Ag Nichtsteroidale Gestagene
US6107295A (en) * 1997-08-01 2000-08-22 Merck Patent Gesellschaft Mit Beschrankter Haftung Arylalkanoyl pyridazines
DE19850701A1 (de) 1998-11-04 2000-05-11 Merck Patent Gmbh Benzoylpyridazine
US6417189B1 (en) 1999-11-12 2002-07-09 Gpi Nil Holdings, Inc. AZA compounds, pharmaceutical compositions and methods of use
US7253169B2 (en) 1999-11-12 2007-08-07 Gliamed, Inc. Aza compounds, pharmaceutical compositions and methods of use
DE10064997A1 (de) 2000-12-23 2002-06-27 Merck Patent Gmbh Benzoylpyridazine
US7402704B2 (en) * 2004-04-14 2008-07-22 Amgen Inc. Arylsulfones and uses related thereto
ES2814343T3 (es) 2006-10-24 2021-03-26 Allergan Pharmaceuticals Int Ltd Composiciones y métodos para suprimir las proliferaciones endometriales
EA201070715A1 (ru) * 2007-12-20 2011-02-28 Тева Вимен'С Хелс, Инк. Режимы дозирования, фармацевтические композиции и упаковки для экстренной контрацепции
TWI539953B (zh) 2008-04-28 2016-07-01 瑞波若斯治療學公司 用於治療乳癌之組成物和方法
JP5894143B2 (ja) 2010-03-22 2016-03-23 リプロス セラピューティクス インコーポレイテッド 抗黄体ホルモンの無毒送達のための組成物および方法
EP3661917B1 (en) 2017-08-04 2022-05-11 Bayer Aktiengesellschaft 6-((3-trifluoromethyl)phenyl)-4,5-dihydropyridazin-3(2h)-one derivatives as pde3a and pde3b inhibitors for treating cancer
JOP20200024A1 (ar) 2017-08-04 2020-02-02 Bayer Ag مركبات ثنائي هيدروكساديازينون
AU2020215088A1 (en) 2019-02-01 2021-07-22 Bayer Aktiengesellschaft 1,2,4-triazin-3(2H)-one compounds for the treatment of hyperproliferative diseases

Also Published As

Publication number Publication date
HU9403841D0 (en) 1995-02-28
AU4667093A (en) 1994-01-31
DK0650480T3 (da) 2002-05-13
DE69331196T2 (de) 2002-07-25
WO1994001412A1 (en) 1994-01-20
PT650480E (pt) 2002-03-28
HUT68424A (en) 1995-06-28
EP0650480A1 (en) 1995-05-03
DE69331196D1 (de) 2002-01-03
ATE209189T1 (de) 2001-12-15
US5684151A (en) 1997-11-04
BR9306661A (pt) 1998-12-08
NZ254534A (en) 1997-12-19
JPH07508987A (ja) 1995-10-05
AU668206B2 (en) 1996-04-26
CA2139307A1 (en) 1994-01-20
EP0650480B1 (en) 2001-11-21

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