ATE209189T1 - 1-arylsulfonyl-3-phenyl-1,4,5,6- tetrahydropyridazinen - Google Patents
1-arylsulfonyl-3-phenyl-1,4,5,6- tetrahydropyridazinenInfo
- Publication number
- ATE209189T1 ATE209189T1 AT93917006T AT93917006T ATE209189T1 AT E209189 T1 ATE209189 T1 AT E209189T1 AT 93917006 T AT93917006 T AT 93917006T AT 93917006 T AT93917006 T AT 93917006T AT E209189 T1 ATE209189 T1 AT E209189T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- group
- chch
- radical
- proviso
- Prior art date
Links
- GVNVAWHJIKLAGL-UHFFFAOYSA-N 2-(cyclohexen-1-yl)cyclohexan-1-one Chemical compound O=C1CCCCC1C1=CCCCC1 GVNVAWHJIKLAGL-UHFFFAOYSA-N 0.000 abstract 3
- 101150065749 Churc1 gene Proteins 0.000 abstract 3
- 102100038239 Protein Churchill Human genes 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000000583 progesterone congener Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650905—Six-membered rings having the nitrogen atoms in the positions 1 and 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Physical Education & Sports Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90698492A | 1992-07-01 | 1992-07-01 | |
| US8098693A | 1993-06-21 | 1993-06-21 | |
| PCT/US1993/006394 WO1994001412A1 (en) | 1992-07-01 | 1993-07-01 | 1-arylsulphonyl, arylcarbonyl and 1-arylphosphonyl-3-phenyl-1,4,5,6-tetrahydropyridazines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE209189T1 true ATE209189T1 (de) | 2001-12-15 |
Family
ID=26764215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93917006T ATE209189T1 (de) | 1992-07-01 | 1993-07-01 | 1-arylsulfonyl-3-phenyl-1,4,5,6- tetrahydropyridazinen |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5684151A (de) |
| EP (1) | EP0650480B1 (de) |
| JP (1) | JPH07508987A (de) |
| AT (1) | ATE209189T1 (de) |
| AU (1) | AU668206B2 (de) |
| BR (1) | BR9306661A (de) |
| CA (1) | CA2139307A1 (de) |
| DE (1) | DE69331196T2 (de) |
| DK (1) | DK0650480T3 (de) |
| ES (1) | ES2168276T3 (de) |
| HU (1) | HUT68424A (de) |
| NZ (1) | NZ254534A (de) |
| PT (1) | PT650480E (de) |
| WO (1) | WO1994001412A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4430755A1 (de) * | 1994-08-30 | 1996-03-07 | Boehringer Mannheim Gmbh | Neue Phosphanoxide, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel |
| US5707985A (en) * | 1995-06-07 | 1998-01-13 | Tanabe Seiyaku Co. Ltd. | Naphthyl-, quinolyl- and isoquinolyl- sulfonamide derivatives as cell adhesion modulators |
| DE19632549A1 (de) * | 1996-08-13 | 1998-02-19 | Merck Patent Gmbh | Arylalkanoylpyridazine |
| DE19723722A1 (de) * | 1997-05-30 | 1998-12-10 | Schering Ag | Nichtsteroidale Gestagene |
| US6107295A (en) * | 1997-08-01 | 2000-08-22 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Arylalkanoyl pyridazines |
| DE19850701A1 (de) | 1998-11-04 | 2000-05-11 | Merck Patent Gmbh | Benzoylpyridazine |
| US7253169B2 (en) | 1999-11-12 | 2007-08-07 | Gliamed, Inc. | Aza compounds, pharmaceutical compositions and methods of use |
| US6417189B1 (en) | 1999-11-12 | 2002-07-09 | Gpi Nil Holdings, Inc. | AZA compounds, pharmaceutical compositions and methods of use |
| DE10064997A1 (de) * | 2000-12-23 | 2002-06-27 | Merck Patent Gmbh | Benzoylpyridazine |
| EP1735275B1 (de) * | 2004-04-14 | 2010-08-18 | Amgen Inc. | Arylsulfone und damit verbundene verwendungen |
| EP3693376A1 (de) | 2006-10-24 | 2020-08-12 | Allergan Pharmaceuticals International Limited | Zusammensetzungen zur unterdrückung der endometriumproliferation |
| JP2011507853A (ja) * | 2007-12-20 | 2011-03-10 | テバ ウィメンズ ヘルス インコーポレイテッド | 緊急避妊のための投与量レジメンならびに薬学的組成物およびパッケージ |
| TWI539953B (zh) | 2008-04-28 | 2016-07-01 | 瑞波若斯治療學公司 | 用於治療乳癌之組成物和方法 |
| EP2550288A1 (de) | 2010-03-22 | 2013-01-30 | Repros Therapeutics Inc. | Zusammensetzungen und verfahren zur nichttoxischen freisetzung von antiprogestinen |
| JOP20200024A1 (ar) | 2017-08-04 | 2020-02-02 | Bayer Ag | مركبات ثنائي هيدروكساديازينون |
| US11897867B2 (en) | 2017-08-04 | 2024-02-13 | Bayer Aktiengesellschaft | 6-phenyl-4,5-dihydropyridazin-3(2H)-one derivatives as PDE3A and PDE3B inhibitors for treating cancer |
-
1993
- 1993-07-01 AU AU46670/93A patent/AU668206B2/en not_active Expired
- 1993-07-01 CA CA002139307A patent/CA2139307A1/en not_active Abandoned
- 1993-07-01 EP EP93917006A patent/EP0650480B1/de not_active Expired - Lifetime
- 1993-07-01 BR BR9306661A patent/BR9306661A/pt not_active Application Discontinuation
- 1993-07-01 DE DE69331196T patent/DE69331196T2/de not_active Expired - Lifetime
- 1993-07-01 US US08/362,476 patent/US5684151A/en not_active Expired - Lifetime
- 1993-07-01 NZ NZ254534A patent/NZ254534A/en not_active IP Right Cessation
- 1993-07-01 WO PCT/US1993/006394 patent/WO1994001412A1/en active IP Right Grant
- 1993-07-01 HU HU9403841A patent/HUT68424A/hu unknown
- 1993-07-01 DK DK93917006T patent/DK0650480T3/da active
- 1993-07-01 AT AT93917006T patent/ATE209189T1/de active
- 1993-07-01 ES ES93917006T patent/ES2168276T3/es not_active Expired - Lifetime
- 1993-07-01 PT PT93917006T patent/PT650480E/pt unknown
- 1993-07-01 JP JP6503486A patent/JPH07508987A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2139307A1 (en) | 1994-01-20 |
| EP0650480B1 (de) | 2001-11-21 |
| DE69331196T2 (de) | 2002-07-25 |
| HUT68424A (en) | 1995-06-28 |
| US5684151A (en) | 1997-11-04 |
| DK0650480T3 (da) | 2002-05-13 |
| HU9403841D0 (en) | 1995-02-28 |
| DE69331196D1 (de) | 2002-01-03 |
| WO1994001412A1 (en) | 1994-01-20 |
| AU668206B2 (en) | 1996-04-26 |
| EP0650480A1 (de) | 1995-05-03 |
| PT650480E (pt) | 2002-03-28 |
| NZ254534A (en) | 1997-12-19 |
| ES2168276T3 (es) | 2002-06-16 |
| BR9306661A (pt) | 1998-12-08 |
| JPH07508987A (ja) | 1995-10-05 |
| AU4667093A (en) | 1994-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE209189T1 (de) | 1-arylsulfonyl-3-phenyl-1,4,5,6- tetrahydropyridazinen | |
| ATE168101T1 (de) | Arylpyridazinone | |
| ATE37179T1 (de) | Dihydropyridazinone. | |
| HUP0300268A2 (hu) | Herbicid hatású benzoilpirazolszármazékok, ilyeneket tartalmazó készítmények és alkalmazásuk | |
| ES8604854A1 (es) | Un procedimiento para la preparacion de un compuesto coulante para el tenido del cabello por oxidacion. | |
| CA2159817A1 (en) | Pyrimidine Acyclonucleoside Derivatives | |
| ES2000779A6 (es) | Un procedimiento para preparar derivados de piridazinona y metodo para reprimir plagas de insectos usando dichos derivados. | |
| AU560607B2 (en) | Pyridazinones their preparation and use and medicaments containing pyridazinones | |
| MX9306995A (es) | Derivados de acido orto-etenilfenilacetico sustituidos. | |
| ATE191465T1 (de) | Carbamoylcarbonsäureamide | |
| TW198680B (de) | ||
| ATE161844T1 (de) | Acyl-(2'-hydroxybiphenyl-2-yl)- phosphinsäuresalze, ihre herstellung und verwendung | |
| ES8402824A1 (es) | Procedimiento para la preparacion de un derivado de acido imidazolcarboxilico. | |
| DK0395527T3 (da) | Imidazobenzodiazepiner og deres salte, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og præparater med indhold deraf | |
| ZA965409B (en) | Iminooxybenzyl compounds, their preparation and their use. | |
| DE3467297D1 (en) | Benzobicyclononane amino derivatives with anticonvulsive properties | |
| ES8307798A1 (es) | Un procedimiento para la preparacion de derivados de piperazilmetil-4-dibenzofuranona, o, dibenzofuranol. | |
| TW289019B (de) |