IT1224636B - Esteri penem 6 sostituiti come agenti antinfiammatori e antidegenerativi. - Google Patents

Esteri penem 6 sostituiti come agenti antinfiammatori e antidegenerativi.

Info

Publication number
IT1224636B
IT1224636B IT8820990A IT2099088A IT1224636B IT 1224636 B IT1224636 B IT 1224636B IT 8820990 A IT8820990 A IT 8820990A IT 2099088 A IT2099088 A IT 2099088A IT 1224636 B IT1224636 B IT 1224636B
Authority
IT
Italy
Prior art keywords
esteri
penem
inflammatory
replaced
degenerative agents
Prior art date
Application number
IT8820990A
Other languages
English (en)
Other versions
IT8820990A0 (it
Inventor
Marco Alpegiani
Ettore Perrone
Piergiuseppe Orezzi
Paolo Carminati
Giuseppe Cassinelli
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of IT8820990A0 publication Critical patent/IT8820990A0/it
Application granted granted Critical
Publication of IT1224636B publication Critical patent/IT1224636B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT8820990A 1987-06-19 1988-06-16 Esteri penem 6 sostituiti come agenti antinfiammatori e antidegenerativi. IT1224636B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878714413A GB8714413D0 (en) 1987-06-19 1987-06-19 6-substituted penem esters

Publications (2)

Publication Number Publication Date
IT8820990A0 IT8820990A0 (it) 1988-06-16
IT1224636B true IT1224636B (it) 1990-10-04

Family

ID=10619222

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8820990A IT1224636B (it) 1987-06-19 1988-06-16 Esteri penem 6 sostituiti come agenti antinfiammatori e antidegenerativi.

Country Status (5)

Country Link
US (2) US4954493A (it)
JP (1) JPS6416790A (it)
DE (1) DE3820420A1 (it)
GB (2) GB8714413D0 (it)
IT (1) IT1224636B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8714413D0 (en) * 1987-06-19 1987-07-22 Erba Farmitalia 6-substituted penem esters
EP0544905B1 (en) * 1990-08-20 1998-10-14 Suntory Limited Antibacterial penem compounds
DE69225821T2 (de) * 1991-03-13 1998-11-05 Otsuka Kagaku Kk Penamderivate und Verfahren zu deren Herstellung
GB9110507D0 (en) * 1991-05-15 1991-07-03 Smithkline Beecham Plc Chemical compounds
US5229415A (en) * 1992-03-24 1993-07-20 Merck & Co., Inc. Alkylthio alkyl avermectins are active antiparasitic agents
WO2002098844A1 (de) * 2001-06-01 2002-12-12 Merck Patent Gmbh Verfahren zur herstellung perfluoralkansulfonsäureresten
JP2009160460A (ja) * 2009-04-24 2009-07-23 Daito Giken:Kk 遊技島の音響システム

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4482565A (en) * 1980-02-22 1984-11-13 Farmitalia Carlo Erba S.P.A. β-Lactam-containing antibacterial agents and β-lactamase inhibitors
GB2079744A (en) * 1980-07-04 1982-01-27 Erba Farmitalia 6-Alkyl-2-functionalized penems
IT1190842B (it) * 1981-06-30 1988-02-24 Erba Farmitalia Via di sintesi di derivati otticamente attivi dell'acido 2-penem-3-carbossilico
US4623645A (en) * 1983-04-18 1986-11-18 Merck & Co., Inc. Substituted cephalosporin sulfoxides as anti-inflammatory and antidegenerative agents
US4711886A (en) * 1984-07-02 1987-12-08 Merck & Co., Inc. β-lactam derivatives as anti-inflammatory and antidegenerative agents
US4797396A (en) * 1984-07-02 1989-01-10 Merck & Co., Inc. β-Lactam derivatives as anti-inflammatory and antidegenerative agents
US4847247A (en) * 1984-07-30 1989-07-11 Merck & Co., Inc. Penicillin derivatives as anti-inflammatory and antidegenerative agents
GB8714413D0 (en) * 1987-06-19 1987-07-22 Erba Farmitalia 6-substituted penem esters

Also Published As

Publication number Publication date
DE3820420A1 (de) 1988-12-29
US4954493A (en) 1990-09-04
GB2206113A (en) 1988-12-29
JPS6416790A (en) 1989-01-20
GB8813918D0 (en) 1988-07-20
IT8820990A0 (it) 1988-06-16
GB8714413D0 (en) 1987-07-22
US5089489A (en) 1992-02-18
GB2206113B (en) 1991-10-16

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