ITMI952431A0 - - Google Patents

Info

Publication number
ITMI952431A0
ITMI952431A0 ITMI952431A ITMI952431A ITMI952431A0 IT MI952431 A0 ITMI952431 A0 IT MI952431A0 IT MI952431 A ITMI952431 A IT MI952431A IT MI952431 A ITMI952431 A IT MI952431A IT MI952431 A0 ITMI952431 A0 IT MI952431A0
Authority
IT
Italy
Application number
ITMI952431A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of ITMI952431A0 publication Critical patent/ITMI952431A0/it
Priority to IT95MI002431A priority Critical patent/IT1276162B1/it
Priority to ES96941022T priority patent/ES2216075T3/es
Priority to JP9519409A priority patent/JP2000500758A/ja
Priority to BR9611642A priority patent/BR9611642A/pt
Priority to EP96941022A priority patent/EP0862575B1/en
Priority to PCT/EP1996/005202 priority patent/WO1997019091A1/en
Priority to AU10316/97A priority patent/AU1031697A/en
Priority to PT96941022T priority patent/PT862575E/pt
Priority to CA002238389A priority patent/CA2238389C/en
Priority to AT96941022T priority patent/ATE259369T1/de
Priority to DE69631542T priority patent/DE69631542T2/de
Priority to US09/077,196 priority patent/US6242433B1/en
Publication of ITMI952431A1 publication Critical patent/ITMI952431A1/it
Application granted granted Critical
Publication of IT1276162B1 publication Critical patent/IT1276162B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04—Diamides of sulfuric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04—Diamides of sulfuric acids
    • C07C307/06—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • C07F9/3821—Acyclic saturated acids which can have further substituents on alkyl substituted by B, Si, P or a metal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3826—Acyclic unsaturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT95MI002431A 1995-11-23 1995-11-23 Geranilgeranil-derivati,procedimento per la loro preparazione e relative composizioni farmaceutiche IT1276162B1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT95MI002431A IT1276162B1 (it) 1995-11-23 1995-11-23 Geranilgeranil-derivati,procedimento per la loro preparazione e relative composizioni farmaceutiche
AU10316/97A AU1031697A (en) 1995-11-23 1996-11-21 Novel geranylgeranyl-derivatives, process for the preparation thereof and related pharmaceutical compositions
CA002238389A CA2238389C (en) 1995-11-23 1996-11-21 Novel geranylgeranyl-derivatives, process for the preparation thereof and related pharmaceutical compositions
BR9611642A BR9611642A (pt) 1995-11-23 1996-11-21 Compostos composição farmacéutica e processo para a preparação de compostos
EP96941022A EP0862575B1 (en) 1995-11-23 1996-11-21 Novel geranylgeranyl-derivatives, process for the preparation thereof and related pharmaceutical compositions
PCT/EP1996/005202 WO1997019091A1 (en) 1995-11-23 1996-11-21 Novel geranylgeranyl-derivatives, process for the preparation thereof and related pharmaceutical compositions
ES96941022T ES2216075T3 (es) 1995-11-23 1996-11-21 Nuevos derivados de geranilgeranilo, procedimiento para la preparacion de estos y composiciones farmaceuticas relacionadas.
PT96941022T PT862575E (pt) 1995-11-23 1996-11-21 Novos derivados de geranilgeranilo processo para a sua preparacao e composicoes farmaceuticas relacionadas
JP9519409A JP2000500758A (ja) 1995-11-23 1996-11-21 新規なゲラニルゲラニル誘導体、その製造方法および関連する薬剤組成物
AT96941022T ATE259369T1 (de) 1995-11-23 1996-11-21 Neue geranylgeranylderivate, verfahren zu deren herstellung und entsprechende pharmazeutische zusammensetzungen
DE69631542T DE69631542T2 (de) 1995-11-23 1996-11-21 Neue geranylgeranylderivate, verfahren zu deren herstellung und entsprechende pharmazeutische zusammensetzungen
US09/077,196 US6242433B1 (en) 1995-11-23 1996-11-21 Geranylgeranyl-derivatives, process for the preparation thereof and related pharmaceutical compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95MI002431A IT1276162B1 (it) 1995-11-23 1995-11-23 Geranilgeranil-derivati,procedimento per la loro preparazione e relative composizioni farmaceutiche

Publications (3)

Publication Number Publication Date
ITMI952431A0 true ITMI952431A0 (it) 1995-11-23
ITMI952431A1 ITMI952431A1 (it) 1997-05-23
IT1276162B1 IT1276162B1 (it) 1997-10-27

Family

ID=11372579

Family Applications (1)

Application Number Title Priority Date Filing Date
IT95MI002431A IT1276162B1 (it) 1995-11-23 1995-11-23 Geranilgeranil-derivati,procedimento per la loro preparazione e relative composizioni farmaceutiche

Country Status (12)

Country Link
US (1) US6242433B1 (it)
EP (1) EP0862575B1 (it)
JP (1) JP2000500758A (it)
AT (1) ATE259369T1 (it)
AU (1) AU1031697A (it)
BR (1) BR9611642A (it)
CA (1) CA2238389C (it)
DE (1) DE69631542T2 (it)
ES (1) ES2216075T3 (it)
IT (1) IT1276162B1 (it)
PT (1) PT862575E (it)
WO (1) WO1997019091A1 (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117641A (en) 1996-04-11 2000-09-12 Mitotix, Inc. Assays and reagents for identifying anti-fungal agents and uses related thereto
US6727082B1 (en) 1996-04-11 2004-04-27 Gpc Biotech Inc. Assays and reagents for identifying anti-fungal agents, and uses related thereto
DE69713759T2 (de) 1996-04-11 2003-03-13 Mitotix Inc Assays und reaganzien zur identifizierung von fungiziden wirkstoffen und ihre verwendungen
CA2335366A1 (en) * 1998-06-24 1999-12-29 Merck & Co., Inc. Compositions and methods for treating elevated blood cholesterol
FR2781228B1 (fr) * 1998-07-16 2000-09-29 Pf Medicament Phosphonates insatures derives d'indole
FR2833266B1 (fr) * 2001-12-11 2004-10-22 Mayoly Spindler Lab Nouveaux derives phosphonates, leur procede de preparation, leur utilisation comme modulateurs de l'activite des lymphocytes tgamma9 delta2
US20050065205A1 (en) * 2002-03-07 2005-03-24 Daniel Alkon Methods for Alzheimer's disease treatment and cognitive enhance
DE10242106A1 (de) * 2002-09-11 2004-04-15 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Phosphorgruppenhaltige Carbonsäurederivate mit organisch polymerisierbaren Gruppen
US7517890B2 (en) 2003-11-20 2009-04-14 Children's Hospital Medical Center GTPase inhibitors and methods of use
JP2009508809A (ja) 2005-07-29 2009-03-05 チルドレンズ ホスピタル メディカル センター ＲＡＣ−１ＧＴＰａｓｅのＧＴＰａｓｅ阻害因子とその使用方法およびその結晶構造
US9980942B2 (en) 2012-05-02 2018-05-29 Children's Hospital Medical Center Rejuvenation of precursor cells
US9745331B2 (en) 2012-07-05 2017-08-29 University Of Iowa Research Foundation Therapeutic bisphosphonates
US10028503B2 (en) 2014-06-18 2018-07-24 Children's Hospital Medical Center Platelet storage methods and compositions for same
US20230193328A1 (en) * 2020-03-06 2023-06-22 Board Of Trustees Of Michigan State University Method to produce the anti-microbial diterpenoid leubethanol and related serrulatane-type diterpenes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0356866A3 (en) * 1988-08-29 1991-03-27 E.R. SQUIBB & SONS, INC. Phosphorus-containing squalene synthetase inhibitors and method
US5254715A (en) 1990-11-07 1993-10-19 Warner-Lambert Company Aminosulfonyl carbamates
JPH05239075A (ja) * 1991-08-27 1993-09-17 Eisai Co Ltd 含リンイソプレノイド誘導体
US5298655A (en) 1991-09-27 1994-03-29 Merck & Co., Inc. Farnesyl pyrophosphate analogs
WO1994019357A1 (en) 1993-02-23 1994-09-01 Merrell Dow Pharmaceuticals Inc. Farnesyl:protein transferase inhibitors as anticancer agents
US5510510A (en) * 1994-05-10 1996-04-23 Bristol-Meyers Squibb Company Inhibitors of farnesyl protein transferase
US5574025A (en) * 1994-10-26 1996-11-12 Merck & Co., Inc. Inhibitors of prenyl-protein transferases

Also Published As

Publication number Publication date
ITMI952431A1 (it) 1997-05-23
PT862575E (pt) 2004-06-30
DE69631542D1 (de) 2004-03-18
US6242433B1 (en) 2001-06-05
JP2000500758A (ja) 2000-01-25
DE69631542T2 (de) 2004-12-30
EP0862575A1 (en) 1998-09-09
IT1276162B1 (it) 1997-10-27
EP0862575B1 (en) 2004-02-11
ATE259369T1 (de) 2004-02-15
AU1031697A (en) 1997-06-11
WO1997019091A1 (en) 1997-05-29
CA2238389A1 (en) 1997-05-29
ES2216075T3 (es) 2004-10-16
BR9611642A (pt) 1999-06-01
CA2238389C (en) 2005-10-18

Similar Documents

Publication Publication Date Title
DE69638352D1 (it)
DE69637714D1 (it)
BRPI9612258B1 (it)
FR06C0033I1 (it)
BRPI9612138B1 (it)
DK143195A (it)
ECSDI950232S (it)
FR2729437B1 (it)
DK0727898T3 (it)
ECSDI950233S (it)
ECSDI950231S (it)
ECSDI950230S (it)
ECSDI950229S (it)
ECSDI950223S (it)
AU1627395A (it)
DK126096A (it)
BR7502120U (it)
BR7501503U (it)
CN3033771S (it)
CN3036463S (it)
CN3032568S (it)
CN3032692S (it)
CN3033225S (it)
CN3033635S (it)
CN3031926S (it)

Legal Events

Date Code Title Description
0001 Granted