ITMI951670A0 - Peptidi ciclici analoghi della somatostatina ad attivita' inibitrice dell'ormone della crescita - Google Patents

Peptidi ciclici analoghi della somatostatina ad attivita' inibitrice dell'ormone della crescita

Info

Publication number
ITMI951670A0
ITMI951670A0 ITMI951670A ITMI951670A ITMI951670A0 IT MI951670 A0 ITMI951670 A0 IT MI951670A0 IT MI951670 A ITMI951670 A IT MI951670A IT MI951670 A ITMI951670 A IT MI951670A IT MI951670 A0 ITMI951670 A0 IT MI951670A0
Authority
IT
Italy
Prior art keywords
somatostatin
growth hormone
inhibiting activity
cyclic peptides
hormone inhibiting
Prior art date
Application number
ITMI951670A
Other languages
English (en)
Inventor
Romano Deghenghi
Original Assignee
Romano Deghenghi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romano Deghenghi filed Critical Romano Deghenghi
Publication of ITMI951670A0 publication Critical patent/ITMI951670A0/it
Priority to IT95MI001670A priority Critical patent/IT1277391B1/it
Priority to AU67009/96A priority patent/AU6700996A/en
Priority to CA002227980A priority patent/CA2227980A1/en
Priority to EP96927035A priority patent/EP0842193B1/en
Priority to DK96927035T priority patent/DK0842193T3/da
Priority to ES96927035T priority patent/ES2171704T3/es
Priority to KR1019980700622A priority patent/KR100321448B1/ko
Priority to PCT/EP1996/003149 priority patent/WO1997005167A1/en
Priority to PT96927035T priority patent/PT842193E/pt
Priority to AT96927035T priority patent/ATE213742T1/de
Priority to US08/983,363 priority patent/US5962409A/en
Priority to DE69619530T priority patent/DE69619530T2/de
Priority to JP9507186A priority patent/JPH11510147A/ja
Priority to BR9609801A priority patent/BR9609801A/pt
Publication of ITMI951670A1 publication Critical patent/ITMI951670A1/it
Application granted granted Critical
Publication of IT1277391B1 publication Critical patent/IT1277391B1/it
Priority to HK98109174A priority patent/HK1008225A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IT95MI001670A 1995-07-28 1995-07-28 Peptidi ciclici analoghi della somatostatina ad attivita' inibitrice dell'ormone della crescita IT1277391B1 (it)

Priority Applications (15)

Application Number Priority Date Filing Date Title
IT95MI001670A IT1277391B1 (it) 1995-07-28 1995-07-28 Peptidi ciclici analoghi della somatostatina ad attivita' inibitrice dell'ormone della crescita
PT96927035T PT842193E (pt) 1995-07-28 1996-07-17 Peptidos ciclicos analogos de somatostatina com actividade inibidora sobre a hormona do crescimento
US08/983,363 US5962409A (en) 1995-07-28 1996-07-17 Somatostatin-analogous cyclic peptides with inhibitory activity on growth hormone
EP96927035A EP0842193B1 (en) 1995-07-28 1996-07-17 Somatostatin-analogous cyclic peptides with inhibitory activity on growth hormone
DK96927035T DK0842193T3 (da) 1995-07-28 1996-07-17 Somatostatin-analoge cykliske peptider med hæmmende aktivitet på væksthormon
ES96927035T ES2171704T3 (es) 1995-07-28 1996-07-17 Peptidos ciclicos analogos de somatostatina con actividad inhibidora sobre la hormona del crecimiento.
KR1019980700622A KR100321448B1 (ko) 1995-07-28 1996-07-17 성장호르몬저해활성이있는소마토스타틴-유사체인고리형펩티드
PCT/EP1996/003149 WO1997005167A1 (en) 1995-07-28 1996-07-17 Somatostatin-analogous cyclic peptides with inhibitory activity on growth hormone
AU67009/96A AU6700996A (en) 1995-07-28 1996-07-17 Somatostatin-analogous cyclic peptides with inhibitory activity on growth hormone
AT96927035T ATE213742T1 (de) 1995-07-28 1996-07-17 Zyklische somatostatinanaloge mit wachstumhormon inhibierender aktivität
CA002227980A CA2227980A1 (en) 1995-07-28 1996-07-17 Somatostatin-analogous cyclic peptides with inhibitory activity on growth hormone
DE69619530T DE69619530T2 (de) 1995-07-28 1996-07-17 Zyklische somatostatinanaloge mit wachstumhormon inhibierender aktivität
JP9507186A JPH11510147A (ja) 1995-07-28 1996-07-17 成長ホルモンに対する阻害活性をもつソマトスタチン類似環状ペプチド
BR9609801A BR9609801A (pt) 1995-07-28 1996-07-17 Petídos cíclicos análogos de somatostina com atividade inibitória do desenvolvimento de hormónio
HK98109174A HK1008225A1 (en) 1995-07-28 1998-07-15 Somatostatin-analogous cyclic peptides with inhibitory activity on growth hormone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95MI001670A IT1277391B1 (it) 1995-07-28 1995-07-28 Peptidi ciclici analoghi della somatostatina ad attivita' inibitrice dell'ormone della crescita

Publications (3)

Publication Number Publication Date
ITMI951670A0 true ITMI951670A0 (it) 1995-07-28
ITMI951670A1 ITMI951670A1 (it) 1997-01-28
IT1277391B1 IT1277391B1 (it) 1997-11-10

Family

ID=11372091

Family Applications (1)

Application Number Title Priority Date Filing Date
IT95MI001670A IT1277391B1 (it) 1995-07-28 1995-07-28 Peptidi ciclici analoghi della somatostatina ad attivita' inibitrice dell'ormone della crescita

Country Status (15)

Country Link
US (1) US5962409A (it)
EP (1) EP0842193B1 (it)
JP (1) JPH11510147A (it)
KR (1) KR100321448B1 (it)
AT (1) ATE213742T1 (it)
AU (1) AU6700996A (it)
BR (1) BR9609801A (it)
CA (1) CA2227980A1 (it)
DE (1) DE69619530T2 (it)
DK (1) DK0842193T3 (it)
ES (1) ES2171704T3 (it)
HK (1) HK1008225A1 (it)
IT (1) IT1277391B1 (it)
PT (1) PT842193E (it)
WO (1) WO1997005167A1 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6579967B1 (en) 1999-12-14 2003-06-17 The Salk Institute For Biological Studies Receptor-selective somatostatin analogs
GB0018891D0 (en) 2000-08-01 2000-09-20 Novartis Ag Organic compounds
US7019109B2 (en) * 2001-03-16 2006-03-28 The Salk Institute For Bilogical Studies SSTR1-selective analogs
US20040121407A1 (en) * 2002-09-06 2004-06-24 Elixir Pharmaceuticals, Inc. Regulation of the growth hormone/IGF-1 axis
CN1317031C (zh) * 2005-09-14 2007-05-23 上海第二医科大学附属新华医院 增强实体肿瘤细胞化疗敏感性的高效混合制剂
BRPI0618808A2 (pt) 2005-11-21 2011-09-13 Novartis Ag uso de um inibidor de mtor
EP2752425A4 (en) * 2011-09-04 2015-04-22 Glytech Inc GLYCOSYLATED POLYPEPTIDE AND MEDICAMENT COMPOSITION WITH THIS POLYPEPTIDE

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
GR862206B (en) * 1985-09-12 1986-12-31 Univ Tulane Therapeutic somatostatin analogs
US4904642A (en) * 1985-09-12 1990-02-27 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
IT1240643B (it) * 1990-05-11 1993-12-17 Mediolanum Farmaceutici Spa Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano
HU207104B (en) * 1991-01-25 1993-03-01 Biosignal Kutato Fejlesztoe Kf Process for producing new somatostatin analogs inhibiting tumour growth and pharmaceutical compositions comprising such compounds
AU657770B2 (en) * 1991-06-03 1995-03-23 Mallinckrodt Medical, Inc. Radiolabelled somatostatin derivatives, their preparation and use
JPH07500259A (ja) * 1991-06-06 1995-01-12 ソマネチックス　コーポレイション 光学式大脳酸素濃度計

Also Published As

Publication number Publication date
DE69619530T2 (de) 2002-08-08
IT1277391B1 (it) 1997-11-10
JPH11510147A (ja) 1999-09-07
PT842193E (pt) 2002-06-28
US5962409A (en) 1999-10-05
KR19990035961A (ko) 1999-05-25
EP0842193B1 (en) 2002-02-27
EP0842193A1 (en) 1998-05-20
DK0842193T3 (da) 2002-04-29
HK1008225A1 (en) 1999-05-07
WO1997005167A1 (en) 1997-02-13
KR100321448B1 (ko) 2002-07-31
ATE213742T1 (de) 2002-03-15
AU6700996A (en) 1997-02-26
ITMI951670A1 (it) 1997-01-28
CA2227980A1 (en) 1997-02-13
BR9609801A (pt) 1999-07-06
ES2171704T3 (es) 2002-09-16
DE69619530D1 (de) 2002-04-04

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