ITMI951450A0 - Esteri acilici di amminoacidi achirali di gangiclovir e relativi derivati - Google Patents
Esteri acilici di amminoacidi achirali di gangiclovir e relativi derivatiInfo
- Publication number
- ITMI951450A0 ITMI951450A0 ITMI951450A ITMI951450A ITMI951450A0 IT MI951450 A0 ITMI951450 A0 IT MI951450A0 IT MI951450 A ITMI951450 A IT MI951450A IT MI951450 A ITMI951450 A IT MI951450A IT MI951450 A0 ITMI951450 A0 IT MI951450A0
- Authority
- IT
- Italy
- Prior art keywords
- gangiclovir
- derivatives
- amino acids
- achiral amino
- acylic
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/282,142 US5543414A (en) | 1994-07-28 | 1994-07-28 | Achiral amino acid acyl esters of ganciclovir and its derivatives |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI951450A0 true ITMI951450A0 (it) | 1995-07-06 |
ITMI951450A1 ITMI951450A1 (it) | 1997-01-06 |
IT1279045B1 IT1279045B1 (it) | 1997-12-04 |
Family
ID=23080291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT95MI001450A IT1279045B1 (it) | 1994-07-28 | 1995-07-06 | Esteri acilici di amminoacidi achirali di gangiclovir e relativi derivati |
Country Status (5)
Country | Link |
---|---|
US (1) | US5543414A (it) |
JP (1) | JPH0853452A (it) |
DE (1) | DE19526163A1 (it) |
FR (1) | FR2723093B1 (it) |
IT (1) | IT1279045B1 (it) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9800452D0 (sv) * | 1998-02-13 | 1998-02-13 | Medivir Ab | Antivirals |
US6458772B1 (en) | 1909-10-07 | 2002-10-01 | Medivir Ab | Prodrugs |
DE19535762A1 (de) * | 1995-09-26 | 1997-03-27 | Basf Ag | Verfahren zur Racematspaltung |
US5840890A (en) * | 1996-01-26 | 1998-11-24 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative |
US5869493A (en) * | 1996-02-16 | 1999-02-09 | Medivir Ab | Acyclic nucleoside derivatives |
US6703394B2 (en) | 1996-02-16 | 2004-03-09 | Medivir Ab | Acyclic nucleoside derivatives |
US5891881A (en) * | 1997-11-21 | 1999-04-06 | Clarion Pharmaceuticals Inc. | Aminoheterocycle-substituted glycerols |
US20020128301A1 (en) * | 1998-02-13 | 2002-09-12 | Medivir AB | Non-nucleoside reverse transcriptase inhibitors |
US6107303A (en) * | 1999-03-15 | 2000-08-22 | Demarco; Charlene C. | Treatment of Epstein Barr infection |
US7589233B2 (en) * | 2003-07-29 | 2009-09-15 | Signature R&D Holdings, Llc | L-Threonine derivatives of high therapeutic index |
US8173840B2 (en) * | 2003-07-29 | 2012-05-08 | Signature R&D Holdings, Llc | Compounds with high therapeutic index |
CN101027318B (zh) * | 2004-07-19 | 2016-05-25 | 比奥孔有限公司 | 胰岛素-低聚物共轭物,制剂及其用途 |
US7846937B2 (en) * | 2005-05-25 | 2010-12-07 | Eli Lilly And Company | Cyclopropanecarboxylate esters of acyclovir |
ZA200702234B (en) * | 2006-03-21 | 2008-07-30 | Cipla Ltd | Preparation of ester of purine derivatives |
US8853222B2 (en) * | 2008-03-07 | 2014-10-07 | Ray W. Exley | Treatment of herpes virus related diseases |
CN103562207B (zh) * | 2011-05-31 | 2016-08-17 | 法尔玛赞公司 | 用于制备缬更昔洛韦的2-氨基-9-((2-苯基-1,3-二噁烷-5-基氧基)甲基)-1h-嘌呤-6(9h)-酮化合物的制备方法 |
IN2014MN02105A (it) * | 2012-04-20 | 2015-09-11 | Annji Pharm Co Ltd | |
CN113880819A (zh) * | 2021-09-18 | 2022-01-04 | 浙江大学医学院附属第一医院 | 立他司特的制备方法及其中间体化合物 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1523865A (en) * | 1974-09-02 | 1978-09-06 | Wellcome Found | Purine compunds and salts thereof |
US4355032B2 (en) * | 1981-05-21 | 1990-10-30 | 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent | |
MC1475A1 (fr) * | 1981-08-11 | 1983-06-17 | Wellcome Found | Procede de preparation de derives de la purine a action anti-virale |
NL8202626A (nl) * | 1982-06-29 | 1984-01-16 | Stichting Rega V Z W | Derivaten van 9-(2-hydroxyethoxymethyl)guanine. |
ZW22283A1 (en) * | 1982-10-14 | 1985-05-22 | Wellcome Found | Antiviral compounds |
AP160A (en) * | 1987-08-15 | 1991-11-18 | The Wellcome Foundation Ltd | Therapeutic acyclic nucleosides. |
EP0375329B1 (en) * | 1988-12-19 | 1995-05-31 | The Wellcome Foundation Limited | Antiviral pyrimidine and purine compounds, process for their preparation and pharmaceutical compositions containing them |
US5831075A (en) * | 1993-06-10 | 1998-11-03 | Rolabo Sl | Amino acid ester of nucleoside analogues |
-
1994
- 1994-07-28 US US08/282,142 patent/US5543414A/en not_active Expired - Fee Related
-
1995
- 1995-07-06 IT IT95MI001450A patent/IT1279045B1/it active IP Right Grant
- 1995-07-18 DE DE19526163A patent/DE19526163A1/de not_active Withdrawn
- 1995-07-25 JP JP7188733A patent/JPH0853452A/ja active Pending
- 1995-07-26 FR FR9509077A patent/FR2723093B1/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
IT1279045B1 (it) | 1997-12-04 |
FR2723093A1 (fr) | 1996-02-02 |
FR2723093B1 (fr) | 1997-12-12 |
ITMI951450A1 (it) | 1997-01-06 |
JPH0853452A (ja) | 1996-02-27 |
DE19526163A1 (de) | 1996-02-01 |
US5543414A (en) | 1996-08-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted |