ITMI921235A1 - Oligonucleotidi antisenso ad attivita' antitumorale, composizioni farmaceutiche che li comprendono, e loro impieghi - Google Patents
Oligonucleotidi antisenso ad attivita' antitumorale, composizioni farmaceutiche che li comprendono, e loro impieghiInfo
- Publication number
- ITMI921235A1 ITMI921235A1 IT001235A ITMI921235A ITMI921235A1 IT MI921235 A1 ITMI921235 A1 IT MI921235A1 IT 001235 A IT001235 A IT 001235A IT MI921235 A ITMI921235 A IT MI921235A IT MI921235 A1 ITMI921235 A1 IT MI921235A1
- Authority
- IT
- Italy
- Prior art keywords
- pharmaceutical compositions
- antisense oligonucleotides
- tumor activity
- tumor
- activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Plant Pathology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI921235A IT1255770B (it) | 1992-05-22 | 1992-05-22 | Oligonucleotidi antisenso ad attivita' antitumorale, composizioni farmaceutiche che li comprendono, e loro impieghi |
PCT/EP1993/001287 WO1993024653A1 (en) | 1992-05-22 | 1993-05-21 | Antisense oligonucleotides with antitumoral activity, pharmaceutical compositions which comprise them, and their uses |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI921235A IT1255770B (it) | 1992-05-22 | 1992-05-22 | Oligonucleotidi antisenso ad attivita' antitumorale, composizioni farmaceutiche che li comprendono, e loro impieghi |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI921235A0 ITMI921235A0 (it) | 1992-05-22 |
ITMI921235A1 true ITMI921235A1 (it) | 1993-11-22 |
IT1255770B IT1255770B (it) | 1995-11-15 |
Family
ID=11363352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI921235A IT1255770B (it) | 1992-05-22 | 1992-05-22 | Oligonucleotidi antisenso ad attivita' antitumorale, composizioni farmaceutiche che li comprendono, e loro impieghi |
Country Status (2)
Country | Link |
---|---|
IT (1) | IT1255770B (it) |
WO (1) | WO1993024653A1 (it) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1189573A (ja) * | 1994-10-14 | 1999-04-06 | Yutaka Shindo | アポトーシス関与遺伝子 |
IT1276642B1 (it) * | 1995-03-03 | 1997-11-03 | Consiglio Nazionale Ricerche | Trascritto antisenso presente in linfociti b ed oligodeossinucleotidi sintetici utili per inibirne l'azione |
IT1275862B1 (it) * | 1995-03-03 | 1997-10-24 | Consiglio Nazionale Ricerche | Trascritto antisenso associato ad alcuni tipi di cellule tumorali ed oligodeossinucleotidi sintetici utili nella diagnosi e nel trattamento |
DE19610255B4 (de) * | 1996-03-15 | 2004-11-04 | Universität Heidelberg | Verfahren zur Herstellung von Nukleinsäuresequenzen und Verfahren zum Nachweis von Translokationen zwischen Chromosomen |
US6977244B2 (en) | 1996-10-04 | 2005-12-20 | Board Of Regents, The University Of Texas Systems | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
GB9711919D0 (en) * | 1997-06-09 | 1997-08-06 | Ciba Geigy Ag | Oligonucleotide derivatives |
US7704962B1 (en) | 1997-10-03 | 2010-04-27 | Board Of Regents, The University Of Texas System | Small oligonucleotides with anti-tumor activity |
US7285288B1 (en) | 1997-10-03 | 2007-10-23 | Board Of Regents, The University Of Texas System | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5015568A (en) * | 1986-07-09 | 1991-05-14 | The Wistar Institute | Diagnostic methods for detecting lymphomas in humans |
JPH06501160A (ja) * | 1990-09-17 | 1994-02-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 細胞の増殖をコントロールするための方法及び組成物 |
JPH06508622A (ja) * | 1991-06-18 | 1994-09-29 | テンプル ユニバーシティ−オブ ザ コモンウェルス システム オブ ハイヤーエデュケーション | bcr−ab1アンチセンスオリゴヌクレオチドによる白血球増殖の選択的抑制 |
-
1992
- 1992-05-22 IT ITMI921235A patent/IT1255770B/it active IP Right Grant
-
1993
- 1993-05-21 WO PCT/EP1993/001287 patent/WO1993024653A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO1993024653A1 (en) | 1993-12-09 |
IT1255770B (it) | 1995-11-15 |
ITMI921235A0 (it) | 1992-05-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ITRM930334A0 (it) | Tassano ad attivita' antitumorale. | |
IT1229195B (it) | Derivati xantinici ad attivita' broncodilatatrice e loro applicazioni terapeutiche. | |
IT1277025B1 (it) | Classe di oligonucleotidi fosfodiesterici ad attivita' citotossica composizioni farmaceutiche che li contengono e loro uso | |
IT9019754A0 (it) | Composizioni farmaceutiche,dietetiche o veterinarie ad attivita' eumetabolica | |
ITMI921235A1 (it) | Oligonucleotidi antisenso ad attivita' antitumorale, composizioni farmaceutiche che li comprendono, e loro impieghi | |
IT1271417B (it) | Composti ad attivita' antiistaminica procedimento per la loro preperazione e composizioni farmaceutiche che li contengono. | |
IT1281498B1 (it) | Pirazolo - derivati ad attivita' antitumorale, processo per la loro preparazione e composizioni farmaceutiche che li contengono , e | |
IT8721990A0 (it) | Composizione ad uso topico avente attivita' tricogena, antiforfora ed antiseborroica. | |
IT9047551A0 (it) | Impiego di a-amminofluorochetoni per la preparazione di medicamenti ad attivita' cardiovascolare e antipertensiva. | |
ITMI931806A0 (it) | Composti inibitpri di acil enzima-a-colesterolo-o-acil transferasi ad attivita' terapeutica , loro uso e composizioni farmaceutiche che li contengono | |
NO306672B1 (no) | N,N-dietyl-8,8-dipropyl-2-azaspiro[4,5]decan-2-propanamindimaleat, farmasöytisk blanding omfattende forbindelsen samt anvendelse derav | |
ITMI912652A1 (it) | Medicamento ad attivita' antielastasica. | |
IT8520653A0 (it) | Composti ad attivita'antibatterica, loro preparazione e composizioni farmaceutiche relative. | |
ES1022839Y (es) | Bragas monouso. | |
HUP9901165A3 (en) | Thiamorphinans with neuroprotective activity, pharmaceutical compositions and use of the same | |
IT1243702B (it) | Composti ad attivita' nootropa, procedimento per la loro preparazione e relative composizioni farmaceutiche | |
ITRM920605A0 (it) | Oligonucleotidi antisenso e loro uso | |
ITMI921252A0 (it) | Composizione farmaceutica ad attivita' antitosse | |
ITMI921950A0 (it) | Composizioni farmaceutiche ad attivita' epato-trofica ed anti-aging | |
ITMI951575A0 (it) | Diammine ad attivita' antinfiammatoria | |
ITRM920045A1 (it) | Composizioni farmaceutiche ad attivita' anti-aging. | |
IT8721539A0 (it) | Composti ad attivita'antibatterica, loro preparazione e composizioni farmaceutiche relative. | |
ITMI910759A0 (it) | Composizione farmaceutica ad attivita' antivirale | |
IT1275533B (it) | Composti dotati di attivita' antivirale e antitumorale,loro preparazione e loro uso farmaceutico | |
IT8921708A0 (it) | Composizioni farmaceutiche ad attivita' immunostimolante. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970522 |