ITMI911662A0 - Processo per la purificazione del virus dell'epatite a(hav) virus cosi' purificato e composizioni vaccinali che lo contengono - Google Patents
Processo per la purificazione del virus dell'epatite a(hav) virus cosi' purificato e composizioni vaccinali che lo contengonoInfo
- Publication number
- ITMI911662A0 ITMI911662A0 IT91MI1662A ITMI911662A ITMI911662A0 IT MI911662 A0 ITMI911662 A0 IT MI911662A0 IT 91MI1662 A IT91MI1662 A IT 91MI1662A IT MI911662 A ITMI911662 A IT MI911662A IT MI911662 A0 ITMI911662 A0 IT MI911662A0
- Authority
- IT
- Italy
- Prior art keywords
- hav
- hepatitis
- virus
- purified
- purification
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title 1
- 208000006454 hepatitis Diseases 0.000 title 1
- 231100000283 hepatitis Toxicity 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32411—Hepatovirus, i.e. hepatitis A virus
- C12N2770/32434—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32411—Hepatovirus, i.e. hepatitis A virus
- C12N2770/32451—Methods of production or purification of viral material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI911662A IT1248075B (it) | 1991-06-18 | 1991-06-18 | Processo per la purificazione del virus dell'epatite a (hav), virus cosi` purificato e composizioni vaccinali che lo contengono. |
EP92109524A EP0522291B1 (en) | 1991-06-18 | 1992-06-05 | Process for purifying hepatitis a virus (HAV), virus thus purified and vaccine compositions containing it |
ES92109524T ES2104771T3 (es) | 1991-06-18 | 1992-06-05 | Procedimiento para purificar el virus de la hepatitis a (vha), el virus de dicha forma purificado y composiciones de vacunas que los contienen. |
DK92109524.6T DK0522291T3 (da) | 1991-06-18 | 1992-06-05 | Fremgangsmåde til rensning af hepatitis A-virus (HAV), således renset virus og vaccinepræparater indeholdende dette |
AT92109524T ATE156187T1 (de) | 1991-06-18 | 1992-06-05 | Verfahren zum reinigen von hepatits-a-virus (hav), so gereinigter virus und impfstoffzusammensetzungen, die ihn enthalten |
DE69221225T DE69221225T2 (de) | 1991-06-18 | 1992-06-05 | Verfahren zum Reinigen von Hepatits-A-Virus (HAV), so gereinigter Virus und Impfstoffzusammensetzungen, die ihn enthalten |
JP4181643A JPH07177882A (ja) | 1991-06-18 | 1992-06-17 | A型肝炎ウイルス(hav) の精製方法、こうして精製されたウイルス及びそれを含むワクチン組成物 |
US08/276,780 US5607851A (en) | 1991-06-18 | 1994-07-18 | Process for purifying hepatitis a virus (HAV), and vaccine compositions containing hepatitis a virus |
US08/457,310 US5719049A (en) | 1991-06-18 | 1995-06-01 | Process for purifying hepatitis A virus (HAV), virus thus purified and vaccine compositions containing it |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI911662A IT1248075B (it) | 1991-06-18 | 1991-06-18 | Processo per la purificazione del virus dell'epatite a (hav), virus cosi` purificato e composizioni vaccinali che lo contengono. |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI911662A0 true ITMI911662A0 (it) | 1991-06-18 |
ITMI911662A1 ITMI911662A1 (it) | 1992-12-18 |
IT1248075B IT1248075B (it) | 1995-01-05 |
Family
ID=11360137
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI911662A IT1248075B (it) | 1991-06-18 | 1991-06-18 | Processo per la purificazione del virus dell'epatite a (hav), virus cosi` purificato e composizioni vaccinali che lo contengono. |
Country Status (8)
Country | Link |
---|---|
US (2) | US5607851A (it) |
EP (1) | EP0522291B1 (it) |
JP (1) | JPH07177882A (it) |
AT (1) | ATE156187T1 (it) |
DE (1) | DE69221225T2 (it) |
DK (1) | DK0522291T3 (it) |
ES (1) | ES2104771T3 (it) |
IT (1) | IT1248075B (it) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ225583A (en) * | 1987-08-06 | 1991-07-26 | Merck & Co Inc | Process for purifying hepatitis a virions (hav) |
FR2686084B1 (fr) * | 1992-01-10 | 1995-12-22 | Bioprojet Soc Civ | Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques. |
USRE37303E1 (en) * | 1992-01-10 | 2001-07-31 | Institut National Del La Sante Et De La Recherche Medicale | Imidazole compounds and their therapeutic applications |
FR2696748B1 (fr) * | 1992-10-14 | 1994-12-30 | Pasteur Merieux Serums Vacc | Procédé de préparation d'antigènes et de vaccins de l'hépatite A (HAV). |
AU722196B2 (en) | 1995-08-30 | 2000-07-27 | Genzyme Corporation | Chromatographic purification of adenovirus and AAV |
US7732129B1 (en) * | 1998-12-01 | 2010-06-08 | Crucell Holland B.V. | Method for the production and purification of adenoviral vectors |
AU732703B2 (en) * | 1996-11-20 | 2001-04-26 | Crucell Holland B.V. | An improved method for the production and purification of adenoviral vectors |
US20080261289A1 (en) * | 1996-12-13 | 2008-10-23 | Schering-Plough Corporation | Compositions comprising viruses and methods for concentrating virus preparations |
DE69739961D1 (de) * | 1996-12-13 | 2010-09-23 | Schering Corp | Methoden zur Virus-Reinigung |
US6261823B1 (en) | 1996-12-13 | 2001-07-17 | Schering Corporation | Methods for purifying viruses |
US6544769B1 (en) * | 1996-12-13 | 2003-04-08 | Schering Corporation | Compostions comprising viruses and methods for concentrating virus preparations |
US6689600B1 (en) * | 1998-11-16 | 2004-02-10 | Introgen Therapeutics, Inc. | Formulation of adenovirus for gene therapy |
US6855535B2 (en) * | 2001-12-10 | 2005-02-15 | Baxter Healthcare S.A. | Method of large scale production of Hepatitis A virus |
US7901921B2 (en) * | 2004-10-22 | 2011-03-08 | Oncolytics Biotech Inc. | Viral purification methods |
EP1815029A4 (en) * | 2004-11-03 | 2009-06-10 | Introgen Therapeutics Inc | NEW PROCESS FOR THE PRODUCTION AND PURIFICATION OF ADENOVIRAL VECTORS |
JP4670583B2 (ja) * | 2005-10-20 | 2011-04-13 | チッソ株式会社 | 水溶性カチオン性磁気微粒子を用いた脂質ベシクルの分離又は検出方法 |
CA2713891A1 (en) * | 2008-02-12 | 2009-08-20 | Sanofi Pasteur Limited | Methods using ion exchange and gel filtration chromatography for poxvirus purification |
SG184833A1 (en) | 2010-04-14 | 2012-11-29 | Emd Millipore Corp | Methods of producing high titer, high purity virus stocks and methods of use thereof |
CN101816786B (zh) * | 2010-04-30 | 2012-09-05 | 长春生物制品研究所有限责任公司 | 一种甲型肝炎灭活疫苗及其制备方法 |
EP3695849A1 (en) | 2019-02-13 | 2020-08-19 | Mediagnost Gesellschaft für Forschung und Herstellung von Diagnostika GmbH | Method for extracting hepatitis a virus (hav) antigen from cell culture |
JP6898535B1 (ja) * | 2020-06-16 | 2021-07-07 | HOYA Technosurgical株式会社 | アパタイトカラムを使用したウイルスの精製方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8205892D0 (sv) * | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
US4624918A (en) * | 1984-07-09 | 1986-11-25 | Genentech, Inc. | Purification process for hepatitis surface antigen and product thereof |
JPS6147186A (ja) * | 1984-08-09 | 1986-03-07 | Chemo Sero Therapeut Res Inst | インフルエンザウイルスの精製方法 |
JPS6147185A (ja) * | 1984-08-09 | 1986-03-07 | Chemo Sero Therapeut Res Inst | 日本脳炎ウイルスの精製方法 |
US4673634A (en) * | 1985-03-08 | 1987-06-16 | The United States Of America As Represented By The Department Of Health And Human Services | Purified antigen from non-A, non-B hepatitis causing factor |
NZ225583A (en) * | 1987-08-06 | 1991-07-26 | Merck & Co Inc | Process for purifying hepatitis a virions (hav) |
US5011915A (en) * | 1987-10-26 | 1991-04-30 | Merck & Co., Inc. | Process for purifying recombinant hepatitis antigens |
EP0327801A1 (en) * | 1988-01-08 | 1989-08-16 | Deutsches Primatenzentrum Gesellschaft Mbh | HIV-2-type retroviruses of primates, vaccines, diagnostic and pharmaceutical compositions |
US5004688A (en) * | 1988-04-15 | 1991-04-02 | Phillips Petroleum Company | Purification of hepatitis proteins |
JPH085804B2 (ja) * | 1988-04-28 | 1996-01-24 | 財団法人化学及血清療法研究所 | A型及びb型肝炎混合アジュバントワクチン |
-
1991
- 1991-06-18 IT ITMI911662A patent/IT1248075B/it active IP Right Grant
-
1992
- 1992-06-05 DK DK92109524.6T patent/DK0522291T3/da active
- 1992-06-05 AT AT92109524T patent/ATE156187T1/de active
- 1992-06-05 ES ES92109524T patent/ES2104771T3/es not_active Expired - Lifetime
- 1992-06-05 DE DE69221225T patent/DE69221225T2/de not_active Expired - Lifetime
- 1992-06-05 EP EP92109524A patent/EP0522291B1/en not_active Expired - Lifetime
- 1992-06-17 JP JP4181643A patent/JPH07177882A/ja not_active Withdrawn
-
1994
- 1994-07-18 US US08/276,780 patent/US5607851A/en not_active Expired - Lifetime
-
1995
- 1995-06-01 US US08/457,310 patent/US5719049A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5607851A (en) | 1997-03-04 |
ITMI911662A1 (it) | 1992-12-18 |
ATE156187T1 (de) | 1997-08-15 |
EP0522291B1 (en) | 1997-07-30 |
ES2104771T3 (es) | 1997-10-16 |
DK0522291T3 (da) | 1997-08-18 |
EP0522291A1 (en) | 1993-01-13 |
DE69221225T2 (de) | 1998-03-19 |
US5719049A (en) | 1998-02-17 |
DE69221225D1 (de) | 1997-09-04 |
JPH07177882A (ja) | 1995-07-18 |
IT1248075B (it) | 1995-01-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970626 |