ITMI20020951A0 - Derivati multifunzionali del polietilenglicole loro preparazione ed impiego - Google Patents

Derivati multifunzionali del polietilenglicole loro preparazione ed impiego

Info

Publication number
ITMI20020951A0
ITMI20020951A0 IT2002MI000951A ITMI20020951A ITMI20020951A0 IT MI20020951 A0 ITMI20020951 A0 IT MI20020951A0 IT 2002MI000951 A IT2002MI000951 A IT 2002MI000951A IT MI20020951 A ITMI20020951 A IT MI20020951A IT MI20020951 A0 ITMI20020951 A0 IT MI20020951A0
Authority
IT
Italy
Prior art keywords
preparation
polyethylene glycol
multifunctional derivatives
multifunctional
derivatives
Prior art date
Application number
IT2002MI000951A
Other languages
English (en)
Inventor
Gian Maria Bonora
Sara Drioli
Maurizio Ballico
Original Assignee
Univ Degli Studi Trieste
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Trieste filed Critical Univ Degli Studi Trieste
Priority to IT2002MI000951A priority Critical patent/ITMI20020951A1/it
Publication of ITMI20020951A0 publication Critical patent/ITMI20020951A0/it
Priority to PCT/EP2003/004620 priority patent/WO2003093346A1/en
Priority to AU2003229769A priority patent/AU2003229769A1/en
Publication of ITMI20020951A1 publication Critical patent/ITMI20020951A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/02—Applications for biomedical use
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polyethers (AREA)
  • Medicinal Preparation (AREA)
IT2002MI000951A 2002-05-06 2002-05-06 Derivati multifunzionali del polietilenglicole loro preparazione ed impiego ITMI20020951A1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT2002MI000951A ITMI20020951A1 (it) 2002-05-06 2002-05-06 Derivati multifunzionali del polietilenglicole loro preparazione ed impiego
PCT/EP2003/004620 WO2003093346A1 (en) 2002-05-06 2003-05-02 Multifunctional polyethylene glycol derivatives: preparation and use
AU2003229769A AU2003229769A1 (en) 2002-05-06 2003-05-02 Multifunctional polyethylene glycol derivatives: preparation and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2002MI000951A ITMI20020951A1 (it) 2002-05-06 2002-05-06 Derivati multifunzionali del polietilenglicole loro preparazione ed impiego

Publications (2)

Publication Number Publication Date
ITMI20020951A0 true ITMI20020951A0 (it) 2002-05-06
ITMI20020951A1 ITMI20020951A1 (it) 2003-11-06

Family

ID=11449835

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2002MI000951A ITMI20020951A1 (it) 2002-05-06 2002-05-06 Derivati multifunzionali del polietilenglicole loro preparazione ed impiego

Country Status (3)

Country Link
AU (1) AU2003229769A1 (it)
IT (1) ITMI20020951A1 (it)
WO (1) WO2003093346A1 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008509692A (ja) * 2004-08-16 2008-04-03 ノボ ノルディスク アクティーゼルスカブ ペプチドの多量体
CU23556A1 (es) * 2005-11-30 2010-07-20 Ct Ingenieria Genetica Biotech Estructura polimérica semejante a dendrímero para la obtención de conjugados de interés farmacéutico
RU2009114154A (ru) * 2006-09-15 2010-10-20 Энзон Фармасьютикалз, Инк. (Us) Полимерные пролекарства с направленной доставкой, содержащие полифункциональные линкеры
EP1955712A1 (en) * 2007-02-09 2008-08-13 Scil proteins GmbH Multimeric conjugate
US11725073B2 (en) 2020-12-29 2023-08-15 Hongene Biotech Corporation Compositions and methods for liquid phase oligonucleotide synthesis
US11851454B2 (en) 2021-12-30 2023-12-26 Hongene Biotech Corporation Compositions and methods for liquid phase oligonucleotide synthesis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643575A (en) * 1993-10-27 1997-07-01 Enzon, Inc. Non-antigenic branched polymer conjugates
US5932462A (en) * 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
CA2313225A1 (en) * 1997-12-12 1999-06-17 Macromed, Inc. Heterofunctionalized star-shaped poly(ethylene glycols) for protein modification

Also Published As

Publication number Publication date
ITMI20020951A1 (it) 2003-11-06
WO2003093346A1 (en) 2003-11-13
AU2003229769A1 (en) 2003-11-17

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