ITMI20001093A0 - Composizioni a rilascio controllato contenenti un principio attivo, preferibilmente melatonina, e processo di preparazione delle stesse. - Google Patents
Composizioni a rilascio controllato contenenti un principio attivo, preferibilmente melatonina, e processo di preparazione delle stesse.Info
- Publication number
- ITMI20001093A0 ITMI20001093A0 IT2000MI001093A ITMI20001093A ITMI20001093A0 IT MI20001093 A0 ITMI20001093 A0 IT MI20001093A0 IT 2000MI001093 A IT2000MI001093 A IT 2000MI001093A IT MI20001093 A ITMI20001093 A IT MI20001093A IT MI20001093 A0 ITMI20001093 A0 IT MI20001093A0
- Authority
- IT
- Italy
- Prior art keywords
- active ingredient
- preparation process
- controlled release
- compositions containing
- release compositions
- Prior art date
Links
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 title 1
- 239000004480 active ingredient Substances 0.000 title 1
- 238000013270 controlled release Methods 0.000 title 1
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 title 1
- 229960003987 melatonin Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Medicinal Preparation (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2000MI001093A IT1318524B1 (it) | 2000-05-17 | 2000-05-17 | Composizioni a rilascio controllato contenenti un principio attivo,preferibilmente melatonina, e processo di preparazione delle stesse. |
US09/854,802 US20040043065A1 (en) | 2000-05-17 | 2001-05-14 | Controlled release formulations containing an active ingredient, preferably melatonin, and the method of preparation |
US11/983,958 US7858656B2 (en) | 2000-05-17 | 2007-11-13 | Controlled release formulations containing an active ingredient, preferably melatonin and the method of preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2000MI001093A IT1318524B1 (it) | 2000-05-17 | 2000-05-17 | Composizioni a rilascio controllato contenenti un principio attivo,preferibilmente melatonina, e processo di preparazione delle stesse. |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI20001093A0 true ITMI20001093A0 (it) | 2000-05-17 |
ITMI20001093A1 ITMI20001093A1 (it) | 2001-11-19 |
IT1318524B1 IT1318524B1 (it) | 2003-08-27 |
Family
ID=11445069
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT2000MI001093A IT1318524B1 (it) | 2000-05-17 | 2000-05-17 | Composizioni a rilascio controllato contenenti un principio attivo,preferibilmente melatonina, e processo di preparazione delle stesse. |
Country Status (2)
Country | Link |
---|---|
US (2) | US20040043065A1 (it) |
IT (1) | IT1318524B1 (it) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080171085A1 (en) * | 2007-01-11 | 2008-07-17 | Natrol, Inc. | Novel biphasic delivery system for a pharmaceutical or nutraceutical composition and method of administration |
CA2681158C (en) | 2007-03-13 | 2018-09-18 | Nutrition 21, Inc. | Methods and compositions for the sustained release of chromium |
US20080254121A1 (en) * | 2007-04-10 | 2008-10-16 | Iomedix Sleep International Srl | Multi-layer melatonin composition |
WO2009002867A2 (en) | 2007-06-26 | 2008-12-31 | Nutrition 21, Inc. | Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement |
IT1401142B1 (it) * | 2010-07-26 | 2013-07-12 | Ambros Pharma S R L | Procedimento per la preparazione di compresse a rilascio controllato comprendenti melatonina |
US9532952B2 (en) | 2011-01-28 | 2017-01-03 | Physician's Seal, LLC | Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients |
WO2012103411A2 (en) | 2011-01-28 | 2012-08-02 | Zx Pharma, Llc | Controlled-release melatonin composition and related methods |
ITMI20110332A1 (it) * | 2011-03-03 | 2012-09-04 | Ambros Pharma S R L | Formulazioni contenenti melatonina a rilascio pulsatile o sequenziale e procedimento per la loro preparazione |
CN104840439B (zh) * | 2014-02-17 | 2019-07-23 | 中国科学院上海药物研究所 | 一种褪黑素仿生释药制剂及其制备方法 |
ES2677247T3 (es) | 2014-05-28 | 2018-07-31 | Valpharma S.P.A. | Formulación para administración oral que comprende melatonina en forma estable y método de producción de la misma |
CN104546777A (zh) * | 2014-12-16 | 2015-04-29 | 深圳翰宇药业股份有限公司 | 美乐托宁缓释组合物的制备方法、美乐托宁缓释片的制备方法 |
AU2017217466A1 (en) | 2016-02-11 | 2018-08-23 | Nutrition 21, Llc | Chromium containing compositions for improving health and fitness |
WO2019038586A1 (en) | 2017-08-19 | 2019-02-28 | Ftf Pharma Private Limited | PHARMACEUTICAL COMPOSITION OF MELATONIN |
CN109350605A (zh) * | 2018-10-24 | 2019-02-19 | 中国药科大学 | 一种褪黑素迟释片及其制备方法 |
CN114259490A (zh) * | 2021-12-23 | 2022-04-01 | 宁波玉健医药有限公司 | 一种褪黑素制剂及其制备方法 |
GB2617102A (en) * | 2022-03-29 | 2023-10-04 | John Hemming Trading Ltd | Sleep therapy |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2718020B1 (fr) * | 1994-04-01 | 1996-05-31 | Biotec Centre Sa | Composition galénique mucoadhésive hétérofonctionnelle. |
-
2000
- 2000-05-17 IT IT2000MI001093A patent/IT1318524B1/it active
-
2001
- 2001-05-14 US US09/854,802 patent/US20040043065A1/en not_active Abandoned
-
2007
- 2007-11-13 US US11/983,958 patent/US7858656B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
IT1318524B1 (it) | 2003-08-27 |
US20040043065A1 (en) | 2004-03-04 |
ITMI20001093A1 (it) | 2001-11-19 |
US20080187587A1 (en) | 2008-08-07 |
US7858656B2 (en) | 2010-12-28 |
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