ITBO960609A1 - Composto naturale ad azione antibiotica ed analgesica - Google Patents
Composto naturale ad azione antibiotica ed analgesica Download PDFInfo
- Publication number
- ITBO960609A1 ITBO960609A1 IT96BO000609A ITBO960609A ITBO960609A1 IT BO960609 A1 ITBO960609 A1 IT BO960609A1 IT 96BO000609 A IT96BO000609 A IT 96BO000609A IT BO960609 A ITBO960609 A IT BO960609A IT BO960609 A1 ITBO960609 A1 IT BO960609A1
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- IT
- Italy
- Prior art keywords
- antibiotic
- natural
- analgesic action
- natural compound
- rev
- Prior art date
Links
- 230000000202 analgesic effect Effects 0.000 title claims abstract description 6
- 230000003115 biocidal effect Effects 0.000 title claims abstract description 6
- 229930014626 natural product Natural products 0.000 title claims description 3
- 241000241413 Propolis Species 0.000 claims abstract description 8
- 229940069949 propolis Drugs 0.000 claims abstract description 8
- 241000899950 Salix glauca Species 0.000 claims abstract description 5
- 239000002253 acid Substances 0.000 claims abstract description 5
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims abstract description 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims abstract description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims abstract description 3
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 3
- 239000011734 sodium Substances 0.000 claims abstract description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 4
- 239000007938 effervescent tablet Substances 0.000 claims description 3
- 238000011005 laboratory method Methods 0.000 claims description 3
- 239000002775 capsule Substances 0.000 claims description 2
- 239000001569 carbon dioxide Substances 0.000 claims description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 238000004040 coloring Methods 0.000 claims 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract description 6
- 240000008530 Rosa canina Species 0.000 abstract description 3
- 235000000539 Rosa canina Nutrition 0.000 abstract description 3
- 235000010337 Rosa dumalis Nutrition 0.000 abstract description 3
- 150000001875 compounds Chemical class 0.000 abstract description 3
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 235000013361 beverage Nutrition 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 description 5
- 239000011782 vitamin Substances 0.000 description 5
- 235000013343 vitamin Nutrition 0.000 description 5
- 229940088594 vitamin Drugs 0.000 description 5
- 229940079593 drug Drugs 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 239000003826 tablet Substances 0.000 description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 241000257303 Hymenoptera Species 0.000 description 2
- 241000220317 Rosa Species 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 239000002221 antipyretic Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229930003935 flavonoid Natural products 0.000 description 2
- 235000017173 flavonoids Nutrition 0.000 description 2
- 150000002215 flavonoids Chemical class 0.000 description 2
- 235000003599 food sweetener Nutrition 0.000 description 2
- 238000002483 medication Methods 0.000 description 2
- 150000007524 organic acids Chemical class 0.000 description 2
- 235000005985 organic acids Nutrition 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 239000003765 sweetening agent Substances 0.000 description 2
- -1 usually Substances 0.000 description 2
- WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 1
- WBYWAXJHAXSJNI-SREVYHEPSA-N Cinnamic acid Chemical compound OC(=O)\C=C/C1=CC=CC=C1 WBYWAXJHAXSJNI-SREVYHEPSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000005141 Otitis Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 241000109365 Rosa arkansana Species 0.000 description 1
- 235000005066 Rosa arkansana Nutrition 0.000 description 1
- NGFMICBWJRZIBI-JZRPKSSGSA-N Salicin Natural products O([C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](CO)O1)c1c(CO)cccc1 NGFMICBWJRZIBI-JZRPKSSGSA-N 0.000 description 1
- 241001278097 Salix alba Species 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- NGFMICBWJRZIBI-UHFFFAOYSA-N alpha-salicin Natural products OC1C(O)C(O)C(CO)OC1OC1=CC=CC=C1CO NGFMICBWJRZIBI-UHFFFAOYSA-N 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 235000021028 berry Nutrition 0.000 description 1
- 125000005587 carbonate group Chemical group 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229930016911 cinnamic acid Natural products 0.000 description 1
- 235000013985 cinnamic acid Nutrition 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 208000019258 ear infection Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000000762 glandular Effects 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000003308 immunostimulating effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 201000009240 nasopharyngitis Diseases 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- NGFMICBWJRZIBI-UJPOAAIJSA-N salicin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=CC=C1CO NGFMICBWJRZIBI-UJPOAAIJSA-N 0.000 description 1
- 229940120668 salicin Drugs 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 206010044008 tonsillitis Diseases 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/76—Salicaceae (Willow family), e.g. poplar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Insects & Arthropods (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Non-Alcoholic Beverages (AREA)
- Seeds, Soups, And Other Foods (AREA)
Description
DESCRIZIONE
dell ? invenzione industriale dal titolo : ?COMPOSTO NATURALE AD AZIONE ANTIBIOTIC A ED ANALGESICA.?
RIAS SUNTO
Composto a base di propoli, rosa canina e salice bianco miscelato ad un carbonato e/o bicarbonato di un metallo alcalino (per esempio sodio) e ad un acido ( per esempio citrico) per ottenere una bevanda effervescente con azione antibiotica ed analgesica.
DESCRIZIONE
E ? noto che attualmente sono facilmente reperibili sul mercato prodotti farmaceutici effervescenti, per rendere pi ? rapida e facile l ? assunzione di farmaci siano essi analgesici, vitaminici o simili.
Ci? diventa molto importante quando c? ? difficolt? a deglutire una compressa, o quando si deve somministrare un farmaco ad un bambino.
E ? altres? noto che nelle malattie da raffreddamento spesso vengono prescritti farmaci ad azione antipiretica ad analgesica e antibiotica, che richiedono un ulteriore apporto di vitamine.
Attualmente in commercio non ? reperibile un prodotto che riunisca in s? tutte le suddette caratteristiche, pertanto si devono somministrare pi? farmaci .
E ? scopo del presente trovato consentire la realizzazione di un prodotto naturale effervescente a base di propoli, rosa canina e salice bianco .
Le propriet? di questi componenti sono note da molto tempo.
La propoli ? una resina che le api raccolgono dalle gemme e dalla corteccia degli alberi e che viene rielaborata dalle api stesse mediante secrezioni ghiandolari . Gi? nell ? antico Egitto la propoli veniva usata per curare alcune malattie e questo uso ? stato poi tramandato anche in Grecia e nell ? antica Roma.
La sua composizione varia ovviamente a seconda dell? habitat naturale in cui il prodotto viene prima elaborato e poi raccolto. Ma fra le sostanze principali sempre presenti ci sono i flavonoidi, l ? acido cinnamico, aminoacidi, vitamine del gruppo B, vitamine del gruppo C e PP.
Di conseguenza la propoli svolge un? azione anestetizzante, antibatterica, antivirale, antimicotica, cicatrizzante, immunostimolante . Per queste caratteristiche ? molto usata in odontoiatria, stomatologia, dermatologia e otorinolaringoiatria.
La rosa canina ? una rosa selvatica i cui fiori danno origine ai frutti, i cinorrodi, che contengono zuccheri, tannini, acidi organici e vitamine naturali : carotenoidi, flavonoidi e vitamina C . La percentuale di quest? ultima ? molto elevata nelle bacche fresche : fino al 1 -2% del peso secco. Grazie a questi componenti la rosa canina presenta delle caratteristiche che la rendono particolarmente adatta in casi di cefalea, rinofaringiti, tonsi lliti, otiti, asma provocata da allergie.
Il salice bianco ha un alto contenuto di salicina che ? il glicoside naturale dell? acido salicilico, principio attivo di molti preparati dell? industria farmaceutica, le cui propriet? antiinfiammatorie, antidolorifiche ed antipiretiche sono note.
Per la preparazione di pastiglie effervescenti, usualmente, si mescolano allo stato secco carbonato o bicarbonato sodico, acidi organici solidi come ad esempio, l ? acido citrico, malico o simili, edulcoranti ed agenti atti a conferire sapore, colore ed aroma alla compressa. Quando la compressa stessa viene introdotta in acqua, il carbonato forma l ? anidride carbonica sotto l ? azione degli acidi e in questo modo si ottiene una bevanda frizzante in cui sono disciolti i vari componenti .
Il composto oggetto della presente invenzione pu? essere preparato anche come polvere solubile, liquido da bere, capsule usando le usuali tecniche note di laboratorio .
A titolo di esempio si cita una compressa effervescente di 4,500 mg. ottenuta con le usuali tecniche di laboratorio, che contiene :
Propoli 12,500 mg.
Salice bianco 25 ,000 mg.
Rosa canina 12,500 mg.
Acido citrico 2.360 mg.
Bicarbonato di sodio 1 .693 ,5 mg.
uniti con edulcoranti, amido , aromi e coloranti .
Il presente trovato descritto in via di esempio, deve intendersi estensibile a quelle varianti accessorie che, come tali, ne rientrano nell ? ambito.
Claims (1)
- RIVENDICAZIONI 1 - COMPOS TO NATURALE AD AZIONE ANTIBIOTIC A ED ANALGESICA caratterizzato dal fatto che ? costituito da estratto di propoli miscelato ad un acido , (per esempio citrico) e da un carbonato o bicarbonato (per esempio di sodio) per originare anidride carbonica a contatto con l? acqua. 2- COMPOSTO NATURALE come alla riv. 1 caratterizzato dal fatto di avere fra i suoi componenti estratto di salice bianco e di rosa canina. 3 - COMPO STO NATURALE come alle rivv. 1 e 2 caratterizzato dal fatto di avere fra i suoi componenti sostanze edulcoranti, coloranti e aromatizzanti . 4- COMPO STO NATURALE come al l e rivv. precedenti caratterizzato dal fatto che pu? essere sotto forma di compressa effervescente, polvere solubile, liquido da bere e capsule; dette forme di realizzazione essendo ottenute con i noti procedimenti di laboratorio .
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96BO000609A IT1286788B1 (it) | 1996-11-28 | 1996-11-28 | Composto naturale ad azione antibiotica ed analgesica |
| PT97830623T PT845262E (pt) | 1996-11-28 | 1997-11-26 | Composicoes efervescente a base de propolis |
| ES97830623T ES2195108T3 (es) | 1996-11-28 | 1997-11-26 | Composiciones efervescentes a base de prepoleos. |
| AT97830623T ATE234074T1 (de) | 1996-11-28 | 1997-11-26 | Brausende propoliszusammensetzungen |
| EP97830623A EP0845262B1 (en) | 1996-11-28 | 1997-11-26 | Effervescent propolis compositions |
| DE69719682T DE69719682D1 (de) | 1996-11-28 | 1997-11-26 | Brausende Propoliszusammensetzungen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96BO000609A IT1286788B1 (it) | 1996-11-28 | 1996-11-28 | Composto naturale ad azione antibiotica ed analgesica |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITBO960609A0 ITBO960609A0 (it) | 1996-11-28 |
| ITBO960609A1 true ITBO960609A1 (it) | 1998-05-28 |
| IT1286788B1 IT1286788B1 (it) | 1998-07-17 |
Family
ID=11341742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT96BO000609A IT1286788B1 (it) | 1996-11-28 | 1996-11-28 | Composto naturale ad azione antibiotica ed analgesica |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0845262B1 (it) |
| AT (1) | ATE234074T1 (it) |
| DE (1) | DE69719682D1 (it) |
| ES (1) | ES2195108T3 (it) |
| IT (1) | IT1286788B1 (it) |
| PT (1) | PT845262E (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5948439A (en) * | 1997-10-31 | 1999-09-07 | Farmo-Nat Ltd. | Effervescent granules |
| CA2317328C (en) * | 1999-09-10 | 2008-01-08 | Dainichiseika Color & Chemicals Mfg. Co., Ltd. | Freshness-retaining agent and method for agricultural/horticultural products |
| KR20020076979A (ko) * | 2001-03-28 | 2002-10-11 | 진승관 | 프로필렌글리콜을 용제로 사용한 수용성 프로폴리스의제조방법 |
| CN104997716B (zh) * | 2015-08-17 | 2020-03-17 | 杭州华胄科技有限公司 | 含蜂胶醇提物的具有抗幽门螺杆菌功效的口腔护理产品 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RO88060A2 (ro) * | 1983-07-20 | 1986-02-28 | Intreprinderea De Medicamente,Ro | Compozitie medicamentoasa cu efect reversor |
| RU2065278C1 (ru) * | 1993-08-30 | 1996-08-20 | Владимир Петрович Чижов | Натуральный поливитаминный комплекс "тонус-м" |
-
1996
- 1996-11-28 IT IT96BO000609A patent/IT1286788B1/it active IP Right Grant
-
1997
- 1997-11-26 DE DE69719682T patent/DE69719682D1/de not_active Expired - Lifetime
- 1997-11-26 PT PT97830623T patent/PT845262E/pt unknown
- 1997-11-26 AT AT97830623T patent/ATE234074T1/de not_active IP Right Cessation
- 1997-11-26 ES ES97830623T patent/ES2195108T3/es not_active Expired - Lifetime
- 1997-11-26 EP EP97830623A patent/EP0845262B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2195108T3 (es) | 2003-12-01 |
| PT845262E (pt) | 2003-08-29 |
| DE69719682D1 (de) | 2003-04-17 |
| IT1286788B1 (it) | 1998-07-17 |
| ITBO960609A0 (it) | 1996-11-28 |
| ATE234074T1 (de) | 2003-03-15 |
| EP0845262B1 (en) | 2003-03-12 |
| EP0845262A1 (en) | 1998-06-03 |
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