IT8322451A0 - Derivati n-sostituiti dell'1-(4'-alchiltiofenil)-2-ammino -1,3-propandiolo. - Google Patents

Derivati n-sostituiti dell'1-(4'-alchiltiofenil)-2-ammino -1,3-propandiolo.

Info

Publication number
IT8322451A0
IT8322451A0 IT8322451A IT2245183A IT8322451A0 IT 8322451 A0 IT8322451 A0 IT 8322451A0 IT 8322451 A IT8322451 A IT 8322451A IT 2245183 A IT2245183 A IT 2245183A IT 8322451 A0 IT8322451 A0 IT 8322451A0
Authority
IT
Italy
Prior art keywords
alkylthiophenyl
propandiol
amino
substituted derivatives
derivatives
Prior art date
Application number
IT8322451A
Other languages
English (en)
Other versions
IT1164389B (it
Inventor
Dario Chiarino
Angelo Carenzi
Davide Della Bella
Mario Fantucci
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of IT8322451A0 publication Critical patent/IT8322451A0/it
Priority to IT22451/83A priority Critical patent/IT1164389B/it
Priority to DE8484201115T priority patent/DE3466981D1/de
Priority to EP84201115A priority patent/EP0136736B1/en
Priority to AT84201115T priority patent/ATE30417T1/de
Priority to CA000460079A priority patent/CA1243319A/en
Priority to ZA845930A priority patent/ZA845930B/xx
Priority to US06/636,714 priority patent/US4638003A/en
Priority to AU31454/84A priority patent/AU581856B2/en
Priority to ES534858A priority patent/ES8604132A1/es
Priority to JP59164724A priority patent/JPS60120853A/ja
Application granted granted Critical
Publication of IT1164389B publication Critical patent/IT1164389B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT22451/83A 1983-08-05 1983-08-05 Derivati n-sostituiti dell'1-(4'-alchiltiofenil)-2-ammino-1,3-propandiolo IT1164389B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT22451/83A IT1164389B (it) 1983-08-05 1983-08-05 Derivati n-sostituiti dell'1-(4'-alchiltiofenil)-2-ammino-1,3-propandiolo
DE8484201115T DE3466981D1 (de) 1983-08-05 1984-07-27 1-(4'-alkylthiophenyl)-2-amino-1,3-propanediol n-substituted derivatives
EP84201115A EP0136736B1 (en) 1983-08-05 1984-07-27 1-(4'-alkylthiophenyl)-2-amino-1,3-propanediol n-substituted derivatives
AT84201115T ATE30417T1 (de) 1983-08-05 1984-07-27 N-substituierte 1-(4'-alkylthiophenyl)-2-amino1,3-propanediol-derivate.
CA000460079A CA1243319A (en) 1983-08-05 1984-07-31 Process for preparing novel n-substituted derivatives of 1-(4'-alkylthiophenyl)-2-amino-1,3-propanediol
ZA845930A ZA845930B (en) 1983-08-05 1984-07-31 1-(4'-alkylthiophenyl)-2-amino-1,3-propanediol n-substituted derivatives
US06/636,714 US4638003A (en) 1983-08-05 1984-08-01 1-(4-alkylthiophenyl)-2-(substituted or unsubstituted piperazine-1-yl)-1,3-propanediol, pharmaceutical compositions containing them useful as antiarrhythmic and vasodilating agents
AU31454/84A AU581856B2 (en) 1983-08-05 1984-08-02 1-(4'-alkylthiophenyl)-2-amino-1, 3-propanediol N-substituted derivatives
ES534858A ES8604132A1 (es) 1983-08-05 1984-08-03 Procedimiento para la obtencion de derivados de 1-(4'-alquiltiofenil)-2-amino-1,3-propandiol
JP59164724A JPS60120853A (ja) 1983-08-05 1984-08-06 １−（４′−アルキルチオフエニル）−２−アミノ−１，３−プロパンジオ−ルｎ−置換誘導体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22451/83A IT1164389B (it) 1983-08-05 1983-08-05 Derivati n-sostituiti dell'1-(4'-alchiltiofenil)-2-ammino-1,3-propandiolo

Publications (2)

Publication Number Publication Date
IT8322451A0 true IT8322451A0 (it) 1983-08-05
IT1164389B IT1164389B (it) 1987-04-08

Family

ID=11196476

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22451/83A IT1164389B (it) 1983-08-05 1983-08-05 Derivati n-sostituiti dell'1-(4'-alchiltiofenil)-2-ammino-1,3-propandiolo

Country Status (10)

Country Link
US (1) US4638003A (it)
EP (1) EP0136736B1 (it)
JP (1) JPS60120853A (it)
AT (1) ATE30417T1 (it)
AU (1) AU581856B2 (it)
CA (1) CA1243319A (it)
DE (1) DE3466981D1 (it)
ES (1) ES8604132A1 (it)
IT (1) IT1164389B (it)
ZA (1) ZA845930B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1164387B (it) * 1983-08-05 1987-04-08 Zambon Spa Derivati n-sostituiti dell'1-(4'-alchilsulfonilfenil)-2-ammino-1,3-propandiolo
IT1205124B (it) * 1987-06-05 1989-03-15 Simens Soteta Italiana Medicin Composto attivo nella terapia carciovascolare
DE3906540A1 (de) * 1989-03-02 1990-09-13 Behringwerke Ag Expressionsvektoren zur synthese von proteinen in der spalthefe schizosaccharomyces pombe
IT1237798B (it) * 1989-10-20 1993-06-17 Zambon Spa Processo per l'inversione stereochimica di (2s,3s)-2-ammino-3-fenil-1 ,3-propandioli nei corrispondenti enantiomeri (2r,3r).
IT1240676B (it) * 1990-04-24 1993-12-17 Agrimont Spa Composizioni ad attivita' erbicida
US5461148A (en) * 1993-09-27 1995-10-24 Schering Corporation Process for preparing benzazepine intermediates for the synthesis of D1 antagonists

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2759970A (en) * 1956-05-09 1956-08-21 Sterling Drug Inc Acylamidoaceto-mercaptophenones
US3056799A (en) * 1959-07-20 1962-10-02 Sterling Drug Inc Processes and intermediate products
GB1321701A (en) * 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same
JPS5245700B2 (it) * 1972-12-28 1977-11-17
JPS5245700A (en) * 1975-10-09 1977-04-11 Showa Denko Kk Excellent method for preparing ring orening polymers
JPS5852640B2 (ja) * 1977-06-06 1983-11-24 味の素株式会社 ペルオキシダ−ゼ活性の測定方法
US4226808A (en) * 1979-08-17 1980-10-07 Schering Corporation 1-Aryl-2-dihalogenodeuterioalkanoylamido-1,3-propanediol antibacterial agents
EP0066919B1 (en) * 1981-05-27 1985-03-20 MAGGIONI FARMACEUTICI S.p.A. 4-alkyl-thiophenyl-ethanolamines, having an activity on the cerebral circulation, the blood platelet-aggregation and the lipemia
IT1164387B (it) * 1983-08-05 1987-04-08 Zambon Spa Derivati n-sostituiti dell'1-(4'-alchilsulfonilfenil)-2-ammino-1,3-propandiolo

Also Published As

Publication number Publication date
DE3466981D1 (de) 1987-12-03
ES534858A0 (es) 1986-01-16
EP0136736B1 (en) 1987-10-28
US4638003A (en) 1987-01-20
AU581856B2 (en) 1989-03-09
CA1243319A (en) 1988-10-18
ZA845930B (en) 1985-06-26
EP0136736A1 (en) 1985-04-10
IT1164389B (it) 1987-04-08
ATE30417T1 (de) 1987-11-15
ES8604132A1 (es) 1986-01-16
JPS60120853A (ja) 1985-06-28
AU3145484A (en) 1985-02-07

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